Mary McGahon

Dr

  • Room 01.014 - Whitla Medical Building

    United Kingdom

19972020

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Article
2020

Ion channels and myogenic activity in retinal arterioles

Barabas, P., Augustine, J., Fernandez Gonzalez, J., McGeown, G., McGahon, M. & Curtis, T., 26 Feb 2020, In : Current Topics in Membranes. 85, 44 p.

Research output: Contribution to journalArticle

2019

Involvement of TRPV1 and TRPV4 Channels in Retinal Angiogenesis

O'Leary, C., McGahon, M. K., Ashraf, S., McNaughten, J., Friedel, T., Cincolà, P., Barabas, P., Fernandez, J. A., Stitt, A. W., McGeown, J. G. & Curtis, T. M., 01 Aug 2019, In : Investigative ophthalmology & visual science. 60, 10, p. 3297-3309

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
154 Downloads (Pure)
2018

A Widening Participation and Outreach Pilot Project

Quinn, J. & McGahon, M., 01 Jun 2018, Queens University Belfast Reflections , 26, p. 5 2 p.

Research output: Contribution to specialist publicationArticle

Open Access
File
20 Downloads (Pure)

Isolation of Retinal Arterioles for Ex Vivo Cell Physiology Studies

Curtis, T. M., McLaughlin, D., O'Hare, M., Kur, J., Barabas, P., Revolta, G., Scholfield, C. N., McGeown, G. & McGahon, M. K., 14 Jul 2018, In : Journal of visualized experiments : JoVE. 137, 19 p., e57944.

Research output: Contribution to journalArticle

Open Access
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53 Downloads (Pure)
2017

Actions of PGLa-AM1 and its [A14K] and [A20K] analogues and their therapeutic potential as anti-diabetic agents

Owolabi, B. O., Musale, V., Ojo, O. O., Moffett, R. C., McGahon, M. K., Curtis, T. M., Conlon, J. M., Flatt, P. R. & Abdel-Wahab, Y. H. A., Jul 2017, In : Biochimie. 138, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
184 Downloads (Pure)

Esculentin-2CHa(1–30) and its analogues: stability and mechanisms of insulinotropic action

Vasu, S., McGahon, M. K., Moffett, R. C., Curtis, T. M., Conlon, J. M., Abdel-Wahab, Y. H. A. & Flatt, P. R., Mar 2017, In : The Journal of endocrinology. 232, p. 423-435 13 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
191 Downloads (Pure)
2016

Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells

El Karim, I. A., McCrudden, M. T. C., McGahon, M. K., Curtis, T. M., Jeanneau, C., Giraud, T., Irwin, C. R., Linden, G. J., Lundy, F. T. & About, I., Apr 2016, In : Journal of Endodontics. 42, 4, p. 589-595 7 p.

Research output: Contribution to journalArticle

File
8 Citations (Scopus)
288 Downloads (Pure)

Diabetes Impairs the Aldehyde Detoxifying Capacity of the Retina

McDowell, R. E., McGahon, M. K., Augustine, J., Chen, M., McGeown, G. & Curtis, T. M., 01 Sep 2016, In : Investigative ophthalmology & visual science. 57, 11, p. 4762-4771 10 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
266 Downloads (Pure)

Molecular mechanisms mediating the beneficial metabolic effects of [Arg4]tigerinin-1R in mice with diet-induced obesity and insulin resistance

Ojo, O. O., Srinivasan, D. K., Owolabi, B. O., McGahon, M. K., Moffett, R. C., Curtis, T. M., Conlon, J. M., Flatt, P. R. & Abdel-Wahab, Y. H. A., Aug 2016, In : Biological Chemistry. 397, 8, p. 753-764 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles

McGahon, M. K., Fernández, J. A., Dash, D. P., McKee, J., Simpson, D. A., Zholos, A. V., McGeown, J. G. & Curtis, T. M., 01 Oct 2016, In : Investigative ophthalmology & visual science. 57, 13, p. 5637-5647 11 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
334 Downloads (Pure)
2015

CaV3.1 T-Type Ca2+ Channels Contribute to Myogenic Signalling in Rat Retinal Arterioles

Fernandez, J. A., McGahon, M. K., McGeown, J. G. & Curtis, T. M., Aug 2015, In : Investigative Ophthalmology and Visual Science. 56, 9, p. 5125-5132 8 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
213 Downloads (Pure)

Exendin-4 protects against post-myocardial infarction remodelling via specific actions on inflammation and the extracellular matrix

Robinson, E., Cassidy, R. S., Tate, M., Zhao, Y., Lockhart, S., Calderwood, D., Church, R., McGahon, M. K., Brazil, D. P., McDermott, B. J., Green, B. D. & Grieve, D. J., 01 Mar 2015, In : Basic Research in Cardiology. 110, 20, p. 20 15 p.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
235 Downloads (Pure)

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

Monaghan, K., McNaughten, J., McGahon, M. K., Kelly, C., Kyle, D., Yong, P. H., McGeown, G. & Curtis, T. M., 05 Jun 2015, In : PloS one. 10, 6, 16 p., e0128359.

Research output: Contribution to journalArticle

Open Access
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26 Citations (Scopus)
299 Downloads (Pure)

TNF alpha-Induced p38MAPK Activation Regulates TRPA1 and TRPV4 Activity in Odontoblast-Like Cells

El Karim, I., McCrudden, M. T. C., Linden, G. J., Abdullah, H., Curtis, T. M., McGahon, M., About, I., Irwin, C. & Lundy, F. T., Nov 2015, In : American Journal of Pathology. 185, 11, p. 2994-3002 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2014

Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in severe asthma

McGarvey, L. P., Butler, C. A., Stokesberry, S., Polley, L., McQuaid, S., Abdullah, H., Ashraf, S., McGahon, M. K., Curtis, T. M., Arron, J., Choy, D., Warke, T. J., Bradding, P., Ennis, M., Zholos, A., Costello, R. W. & Heaney, L. G., Mar 2014, In : Journal of Allergy and Clinical Immunology. 133, 3, p. 704-712 9 p.

Research output: Contribution to journalArticle

Open Access
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68 Citations (Scopus)
391 Downloads (Pure)

Role of ion channels and subcellular Ca2+ signalling in arachidonic acid induced dilation of pressurised retinal arterioles

Kur, J., McGahon, M., Fernández, J. A., Scholfield, N., McGeown, G. & Curtis, T., 02 May 2014, In : Investigative ophthalmology & visual science. 55, 5, p. 2893-2902

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
153 Downloads (Pure)

The Role of K+ and Cl- Channels in the Regulation of Retinal Arteriolar Tone and Blood Flow

Needham, M., McGahon, M. K., Bankhead, P., Gardiner, T. A., Scholfield, C. N., Curtis, T. M. & McGeown, J. G., 07 Apr 2014, In : Investigative ophthalmology & visual science. 55, 4, p. 2157-2165 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2013

Distinctive Profile of IsomiR Expression and Novel MicroRNAs in Rat Heart Left Ventricle

McGahon, M. K., Yarham, J. M., Daly, A., Guduric-Fuchs, J., Ferguson, L. J., Simpson, D. A. & Collins, A., 14 Jun 2013, In : PLoS ONE. 8, 6, 17 p., e65809.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
258 Downloads (Pure)
2012
13 Citations (Scopus)

Pharmacological profiling of store-operated Ca(2+) entry in retinal arteriolar smooth muscle

McGahon, M. K., McKee, J., Dash, D. P., Brown, E., Simpson, D. A., Curtis, T. M., McGeown, J. G. & Scholfield, C. N., Oct 2012, In : Microcirculation (New York, N.Y. : 1994). 19, 7, p. 586-597 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2011

Human Dental Pulp Fibroblasts Express the “Cold-sensing” Transient Receptor Potential Channels TRPA1 and TRPM8

El Karim, I., Linden, G., Curtis, T., About, I., McGahon, M., Irwin, C., Killough, S. & Lundy, F., Apr 2011, In : Journal of Endodontics. 37, 4, p. 473-478 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Human odontoblasts express functional thermo-sensitive TRP channels: implications for dentin sensitivity

El Karim, I., Linden, G., Curtis, T., About, I., McGahon, M., Irwin, C. & Lundy, F., Oct 2011, In : Pain. 152, 10, p. 2211-2223 13 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2010

cAMP/PKA-dependent increases in Ca Sparks, oscillations and SR Ca stores in retinal arteriolar myocytes after exposure to vasopressin.

Jeffries, O., McGahon, M., Bankhead, P., Lozano, M. M., Scholfield, N., Curtis, T. & McGeown, G., Mar 2010, In : Investigative Ophthalmology and Visual Science. 51, 3, p. 1591-1598 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

PAR-2 Regulates Dental Pulp Inflammation Associated with Caries

Lundy, F., About, I., Curtis, T., McGahon, M., Linden, G., Irwin, C. & El Karim, I., Jul 2010, In : Journal of Dental Research. 89, 7, p. 684-688 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2009

Ca2+-activated Cl- current in retinal arteriolar smooth muscle.

McGahon, M., Needham, M. A., Scholfield, C. N., McGeown, G. & Curtis, T., Jan 2009, In : Investigative Ophthalmology and Visual Science. 50(1), 1, p. 364-371 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2008

Modification of smooth muscle Ca2+-sparks by tetracaine: evidence for sequential RyR activation.

Curtis, T., Tumelty, J., Stewart, M., Arora, A., Lai, F. A., McGahon, M., Scholfield, N. & McGeown, G., Feb 2008, In : Cell Calcium. 43(2), 2, p. 142-154 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2007

Diabetes downregulates large-conductance Ca2+-activated potassium beta 1 channel subunit in retinal arteriolar smooth muscle

McGahon, M. K., Dash, D. P., Arora, A., Wall, N., Dawicki, J., Simpson, D. A., Scholfield, C. N., McGeown, G. & Curtis, T., Mar 2007, In : Circulation Research. 100, 5, p. 703-11 9 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.

McGahon, M., Dawicki, J., Arora, A., Simpson, D., Gardiner, T., Stitt, A., Scholfield, N., McGeown, G. & Curtis, T., Oct 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 2, p. H1001-H1008 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

New Developments in Diabetic Retinopathy

Curtis, T., Stitt, A., McGahon, M., Scholfield, N. & McGeown, G., 2007, In : Expert Review of Ophthalmology. 2, p. 947-956 10 p.

Research output: Contribution to journalArticle

Selective downregulation of the BKbeta1 subunit in diabetic arteriolar myocytes

McGahon, M., Zhang, X., Scholfield, N., Curtis, T. & McGeown, G., May 2007, In : Channels (Austin, Tex.). 1 (3), 3, p. e1-e3 3 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2005

A-type K+ current in retinal arteriolar smooth muscle.

McGahon, M., Dawicki, J., Scholfield, N., Gardiner, T., McGeown, G. & Curtis, T., 2005, In : Investigative Ophthalmology and Visual Science. 46, p. 3281-3287 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2003
15 Citations (Scopus)
2000

Effects of BDF 9198 on action potentials and ionic currents from guinea-pig isolated ventricular myocytes.

Yuill, K., McGahon, M., Dooley, P., Doggrell, S. & Hancox, J., 2000, In : British Journal of Pharmacology. 130, 8, p. 1753-1766 14 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
15 Citations (Scopus)
1999
33 Citations (Scopus)
1998
14 Citations (Scopus)