Projects per year
Personal profile
Particulars
Dr Meilan Huang joined Queen’s University Belfast in 2007 as a lecturer. She worked with Prof Fengling Qing's in the Key Laboratory of Organoflorine Chemistry at Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences in 1998-1999. After awarded a PhD degree in Computational Chemistry at Zhejiang University in Feb 2003, she was a postdoc working with Prof Arvi Rauk in the Department of Chemistry at University of Calgary Canada. She was a Welcome Trust research fellow in the Laboratory of Physical and Theoretical Chemistry at University of Oxford working with Prof W. Graham Richards, FRS in 2004-2006 and a research fellow working with Prof Artem Cherkasov in Department of Medicine, University of British Columbia, Canada in 2006-2007. She is a Fellow of Royal Society of Chemistry (FRSC) and a Fellow of Royal Society of Biology (FRSB).
Her main research area is developing and applying Computational methods for biocatalysis and photocatalysis. She studies the interactions and catalytic mechanism of various enzymes to direct the rational design of novel biocatalysts for chemical transformations. She published over 70 full research articles in high-impact peer-reviewed journals. She is the corresponding author of many publications in top chemistry journals including ACS Catalysis (2022, 12: 4037), ACS Applied Materials and Interfaces (2022, 14:47872); SOLAR RRL (2022, 6: 2270071); Chem Comm (2020, 56: 9356 & 2019, 55: 2198), J Am Chem Soc (2019, 141: 19, 7934), Nature Communications (2019, 10: 3198), ACS Catalysis (2016, 6: 11, 7749). She is an Associate Editor of Frontiers in Chemistry.
She has led the Computational team in several major interdisciplinary research projects. She was the PI of Chemistry in the interdisciplinary biotechnological project “Development of a computational and molecular biology platform between QUB and Almac” (2015-2019). She is the PI of chemistry in a new 3-year project (2021-2024) INSIGHT@ "IN Silico-Informed metaGenomic Harvesting Technology", in close collaboration with experimentalists and industry. So far, she has secured over £2m research income with a share of £688k. As the principle supervisor, she has supervised 2 computational postdocs and currently is supervising a postdoc in machine learning.
Research Interests
Computational Chemistry and Biology;
Biocatalysis;
Rational Molecular Design;
Photocatalytis;
Electric Field in Catalysis;
Machine Learning and Statistical Potential
Teaching
Current teaching commitments:
CCE Summer School Programme (Programme Lead)
Advisor of Stuides Chemistry
Advisor of Studies (Intenational students)
CHE1107: Maths for Chemists and Engineers
CCE1102: Physical Chemistry Practical labs
CHM3005C: Computational Chemistry in Drug Discovery (Module Coordinator)
CHM4003: Advanced Physical Chemistry (Module Coordinator)
CHM3010: Practical Skills in Chemistry (Module Coordinator)
CHM3016: Drug Development
CHM4001: Chemistry Research Project
CHM7004: Research Project
Achievements
2021-2024: "INSIGHT: IN Silico Informed metaGenomic Harvesting Technology platform - Development of an advanced and secure enzyme discovery platform for Almac and QUB" Invest NI, RD11181114, £1,299,329. PI of Chemistry
2021-2023: Royal Society: IEC\NSFC\201177 - International Exchanges 2020 “Machine Learning-assisted Directed Evolution of Enzymes”. PI
2021: Newton Fund Research Links Workshop grant-2020-RLWK12-10149 "Catalytic Chemistry and Chemical Technology of C1 process" British Council. PI
2015-2019: "New Biotechnology: Development of Computational and Molecular Biology Platforms for Almac and QUB" Invest NI, RD3014092, £981,360. PI of Chemistry
2017: Queen's Student Union "Education Excellence Award"
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Network
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R3253GFS: IN Silico Informed metaGenomic Harvesting Technology platform (INSIGHT)
Allen, C. C. R., Gilmore, B., Huang, M. & Law, C.
06/01/2021 → …
Project: Research
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R3292CCE: Catalytic Chemistry and Chemical Technology of C1 Process
17/05/2021 → 31/12/2021
Project: Research
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R3671BSC: Development of computational and molecular biology platforms for Almac and QUB
Allen, C. C. R., Huang, M. & Kulakov, L.
21/11/2014 → 30/03/2019
Project: Research
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The substrate specificity in the O-demethylation of 4-alkylguaiacols by Cytochrome P450 AgcAP450
Santos, S., Bommareddy, R., Black, G., Singh, W. & Huang, M., 28 Feb 2023, (Early online date) In: Catalysis Science & Technology.Research output: Contribution to journal › Article › peer-review
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2D/3D heterostructured CsPbI2Br solar cells: a choice for a monolithic all-perovskite tandem device
Yan, L., Li, Y., Li, S., Sun, X., Li, Y., Han, X., Huang, M. & Tao, X., 15 Jun 2022, (Early online date) In: Journal of Materials Chemistry A.Research output: Contribution to journal › Article › peer-review
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An autonomously self-gel-breaking, highly reservoir protective completion fluid tailored for gel-free processing in multi-lateral well construction
Xu, L., Xu, M., Wei, Y., Jie, F., Huang, M., Huang, Y., Xu, J., Wang, L. & Xu, L., Apr 2022, In: Journal of Petroleum Science and Engineering. 211, 110136.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Computer-directed biocatalyst design
Huang, M., 06 Jul 2022.Research output: Contribution to conference › Paper › peer-review
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Computer-Informed Engineering: A New Class I Sesquiterpene Synthase JeSTS4 for the Synthesis of an Unusual C10-(S)-Bicyclogermacrene
Yan, X., Zhou, J., Ge, J., Li, W., Liang, D., Singh, W., Black, G., Nie, S., Liu, J., Sun, M., Qiao, J. & Huang, M., 01 Apr 2022, In: ACS Catalysis. 12, 7, p. 4037-4045 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Prizes
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Fellow of Royal Society of Biology (FRSB)
Huang, Meilan (Recipient), Jan 2022
Prize: Election to learned society
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Fellow of Royal Society of Chemistry (FRSC)
Huang, Meilan (Recipient), May 2021
Prize: Election to learned society
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Guest Research Fellowship awarded by Shanghai Jiaotong University (06/12-06/15)
Huang, Meilan (Recipient), Jun 2012
Prize: National/international honour
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Activities
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Faraday Discussion on Biocatalysis
Meilan Huang (Member of the organising committee)
22 May 2023 → 24 May 2023Activity: Participating in or organising an event types › Participation in conference
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Science at Queen's
Meilan Huang (Participant)
23 Feb 2023Activity: Participating in or organising an event types › Participation in Festival/Exhibition
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ACS Catalysis (Journal)
Meilan Huang (Peer reviewer)
Feb 2023 → …Activity: Publication peer-review and editorial work types › Publication peer-review
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CCE 2023 Summer School
Meilan Huang (Organiser)
2023 → …Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Online promotional talk to BUCT
Meilan Huang (Presenter)
14 Dec 2022Activity: Participating in or organising an event types › Participation in Festival/Exhibition
Press/Media
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£5m national supercomputer at Queen’s set to revolutionise research
11/11/2022
1 Media contribution
Press/Media: Research
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Queen’s scientists awarded significant funding to develop the enzymes of tomorrow
22/03/2021
1 Media contribution
Press/Media: Research
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New Biotechnology: Development of Computational and Molecular Biology Platforms for Almac and QUB
02/02/2015
1 Media contribution
Press/Media: Research