Research output per year
Research output per year
- 1 - 50 out of 320 results
Search results
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2024
Antibiofilm activity of Prevotella species from the cystic fibrosis lung microbiota against Pseudomonas aeruginosa
Grassi, L., Asfahl, K. L., Van den Bossche, S., Maenhout, I., Sass, A., Vande Weygaerde, Y., Van Braeckel, E., Verhasselt, B., Boelens, J., Tunney, M. M., Dandekar, A. A., Coenye, T. & Crabbé, A., 13 Jun 2024, In: Biofilm. 7, 11 p., 100206.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
Diminished airway host innate response in people with cystic fibrosis who experience frequent pulmonary exacerbations
Houston, C. J., Alkhatib, A., Einarsson, G. G., Tunney, M. M., Taggart, C. C. & Downey, D. G., 01 Feb 2024, In: European Respiratory Journal. 63, 2, 15 p., 2301228.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)22 Downloads (Pure) -
Inhaled dry powder liposomal azithromycin for treatment of chronic lower respiratory tract infection
Dallal Bashi, Y. H., Ali, A., Al Ayoub, Y., Assi, K. H., Mairs, R., McCarthy, H. O., Tunney, M. M. & Kett, V. L., 25 Mar 2024, In: International Journal of Pharmaceutics. 653, 11 p., 123841.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)77 Downloads (Pure) -
In vitro activity of cefiderocol against Gram-negative pathogens isolated from people with cystic fibrosis and bronchiectasis
Tunney, M. M., Elborn, J. S., McLaughlin, C. S. & Longshaw, C. M., 02 Mar 2024, In: Journal of Global Antimicrobial Resistance. 36, p. 407-410 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)9 Downloads (Pure) -
Longitudinal changes in the cystic fibrosis airway microbiota with time and treatment
Einarsson, G. G., Sherrard, L. J., Hatch, J. E., Zorn, B., Johnston, E., McGettigan, C., O'Neill, K., Gilpin, D. F., Downey, D. G., Murray, M., Lavelle, G., McElvaney, G., Wolfgang, M. C., Boucher, R., Muhlebach, M. S., Bradbury, I., Elborn, J. S. & Tunney, M. M., Mar 2024, In: Journal of Cystic Fibrosis. 23, 2, p. 252-261 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)63 Downloads (Pure) -
Reversal of levofloxacin resistance in cystic fibrosis-associated Pseudomonas aeruginosa through dual inhibition of efflux pumps and DNA topoisomerases
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 07 Jun 2024, In: Journal of Cystic Fibrosis. 23, Supplement 1, p. S41 1 p., EPS3.04.Research output: Contribution to journal › Meeting abstract › peer-review
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WS09.04 Airway microbial dynamics and inflammation: insights from the Mountain West CF Consortium’s research findings
Einarsson, G. G., Carson, J. P., Elborn, J. S., Adler, F. R., Tunney, M. M. & Liou, T. G., 07 Jun 2024, In: Journal of Cystic Fibrosis. 23, Supplement 1, p. S17 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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2023
A mechanistic analysis of the effect of valaciclovir for EBV suppression on airway inflammation and microbiome in COPD
Linden, D., Guo-Parke, H., Einarsson, G., Carson, S., Lee, A., Fairley, D., Singh, D., Tunney, M., Mcauley, D., Taggart, C. & Kidney, J., 19 May 2023, In: ERJ Open Research. 9, Suppl. 10, 1 p., 59.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Changes in biofilm-tolerance of Pseudomonas aeruginosa to tobramycin following treatment with tobramycin inhalation powder (TIP)
McCleave, R., Einarsson, G., Loebinger, M., Chalmers, J., Elborn, S. J., Haworth, C., Tunney, M. & Sherrard, L., 09 Jun 2023, In: Journal of Cystic Fibrosis. 22, p. S61-S62 2 p., EPS9.04 .Research output: Contribution to journal › Meeting abstract › peer-review
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Characterisation of the CF sputum proteome reveals that innate host defence proteins are depleted in frequent exacerbators
Houston, C., Alkhatib, A., Einarsson, G., Tunney, M., Taggart, C. & Downey, D., 09 Sept 2023, In: European Respiratory Journal. 62, suppl 67, OA1536.Research output: Contribution to journal › Meeting abstract › peer-review
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Development of levofloxacin resistance in clinical Pseudomonas aeruginosa isolates from people with cystic fibrosis in an in vitro variable exposure model
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 01 Jun 2023, In: Journal of Cystic Fibrosis. 22 , Supplement 2, p. S62 1 p., EPS9.06.Research output: Contribution to journal › Meeting abstract › peer-review
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Fusobacterium nucleatum: a novel immune modulator in breast cancer?
Little, A., Tangney, M., Tunney, M. M. & Buckley, N. E., 03 Apr 2023, In: Expert Reviews in Molecular Medicine. 25, 10 p., e15.Research output: Contribution to journal › Review article › peer-review
Open AccessFile13 Citations (Scopus)383 Downloads (Pure) -
In vitro evolution of levofloxacin resistance in lineages of clinical Pseudomonas aeruginosa isolates cultured at different stages of infection from people with cystic fibrosis
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Hoffman, L. R., Tunney, M. M. & Downey, D. G., 01 Jun 2023, In: Journal of Cystic Fibrosis. 22, Supplement 2, p. S135 1 p., P228.Research output: Contribution to journal › Meeting abstract › peer-review
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Long-term therapy with elexacaftor/tezacaftor/ivacaftor (ETI) in cystic fibrosis: improved clinical outcomes but infection and inflammation persist
Tunney, M. M. & Wark, P., 03 Aug 2023, (Early online date) In: European Respiratory Journal. 62, 2, 2301008.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
PharmaCast: COVID and the LAMP Lab
Corbett, D. (Producer), Brown, V., Tunney, M. & Gilpin, D., 27 Feb 2023Research output: Non-textual form › Digital or Visual Products
Open AccessFile19 Downloads (Pure) -
2022
556 Evaluation of total bacterial 16S load and inflammation during intravenously treated pulmonary exacerbations in infrequent and frequent exacerbators
Houston, C., Tunney, M., Taggart, C. & Downey, D., 01 Oct 2022, In: Journal of Cystic Fibrosis. 21, Supplement 2, p. S309-S310 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Antimicrobial resistance in urinary pathogens and culture-independent detection of trimethoprim resistance in urine from patients with urinary tract infection
Somorin, Y. M., Weir, N.-J. M., Pattison, S. H., Crockard, M. A., Hughes, C. M., Tunney, M. M. & Gilpin, D. F., 24 May 2022, In: BMC Microbiology. 22, 144.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)89 Downloads (Pure) -
Characterization of bacteria using Surface-Enhanced Raman Spectroscopy (SERS): influence of microbiological factors on the SERS spectra
Allen, D. M., Einarsson, G. G., Tunney, M. M. & Bell, S. E. J., 05 Jul 2022, In: Analytical Chemistry. 94, 26, p. 9327–9335 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)189 Downloads (Pure) -
Cystic fibrosis airway mucus hyperconcentration produces a vicious cycle of mucin, pathogen, and inflammatory interactions that promote disease persistence
Batson, B. D., Zorn, B. T., Radicioni, G., Livengood, S. S., Kumagai, T., Dang, H., Ceppe, A., Clapp, P. W., Tunney, M., Elborn, J. S., McElvaney, N. G., Muhlebach, M. S., Boucher, R. C., Tiemeyer, M., Wolfgang, M. C. & Kesimer, M., 01 Aug 2022, In: American Journal of Respiratory Cell and Molecular Biology. 67, 2, p. 253-265 13 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Establishing Antimicrobial Susceptibility Testing Methods and Clinical Breakpoints for Inhaled Antibiotic Therapy
Ekkelenkamp, M. B., Díez-Aguilar, M., Tunney, M. M., Elborn, J. S., Fluit, A. C. & Cantón, R., 14 Feb 2022, In: Open Forum Infectious Diseases. 9, 4, ofac082.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)83 Downloads (Pure) -
Induced levofloxacin resistance persists in evolved lineages of Pseudomonas aeruginosa isolates from people with cystic fibrosis after exposure to other inhaled antibiotics
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 01 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S50 1 p., ePS3.05.Research output: Contribution to journal › Meeting abstract › peer-review
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Inhaled powder tobramycin (TIP): cyclical versus continuous treatment: iBEST Study
Alkhatib, A., Einarsson, G. G., Lee, A. J., O’Neill, K., Brown, V., Gilpin, D. F., Angyalosi, G., Malaterre, V., Loebinger, M. R., Chalmers, J. D., Blasi, F., Haworth, C. S., Elborn, J. S. & Tunney, M. M., 10 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S51 1 p., ePS3.08.Research output: Contribution to journal › Meeting abstract › peer-review
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Microbial Community Composition in Explanted Cystic Fibrosis and Control Donor Lungs
Einarsson, G., Vanaudenaerde, B., Spence, C. D., Lee, A. J., Boon, M., Verleden, G. M., Elborn, J. S., Dupont, L., Van Raemdonck, D., Gilpin, D. F., Vos, R., Verleden, S. E. & Tunney, M. M., 16 Mar 2022, In: Frontiers in Cellular and Infection Microbiology. 11, 764585.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)65 Downloads (Pure) -
Modulation, microbiota and inflammation in the adult CF gut: A prospective study
Ronan, N., Einarsson, G., Deane, J., Fouhy, F., Rea, M., Hill, C., Shanahan, F., Elborn, J., Ross, R., McCarthy, M., Murphy, D., Eustace, J., Tunney, M., Stanton, C. & Plant, B., 25 Jun 2022, (Early online date) In: Journal of Cystic Fibrosis.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
P115 Comparison of total bacterial and Pseudomonas aeruginosa load during PEx between infrequent and frequent exacerbators
Houston, C., Tunney, M. M., Taggart, C. C. & Downey, D. G., 01 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S96 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Prevalence of LasB elastase variants from Pseudomonas aeruginosa respiratory isolates and their inhibition by novel LasB inhibitor ANT3273
Llanos, A., Lozano, C., Castandet, J., Zalacain, M., Tunney, M., Mairs, R., Einarsson, G. & Everett, M., 14 Nov 2022.Research output: Contribution to conference › Paper › peer-review
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Pseudomonas aeruginosa infection during long-term suppression treatment with tobramycin inhalation powder (TIP)
McCleave, R., Li, Z., Einarsson, G., Loebinger, M., Chalmers, J., Elborn, S., Haworth, C., McKenna, J., Fairley, D., Allen, D., Tunney, M. & Sherrard, L., 01 Jun 2022, In: Journal of Cystic Fibrosis. 21, Supplement 1, p. S99-S100 P126.Research output: Contribution to journal › Meeting abstract › peer-review
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Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
Rigauts, C., Aizawa, J., Taylor, S., Rogers, G. B., Govaerts, M., Cos, P., Ostyn, L., Sims, S., Vandeplassche, E., Sze, M., Dondelinger, Y., Vereecke, L., Van Acker, H., Simpson, J. L., Burr, L., Willems, A., Tunney, M. M., Cigana, C., Bragonzi, A. & Coenye, T. & 1 others, , 05 May 2022, In: European Respiratory Journal. 59, 5, 2101293.Research output: Contribution to journal › Article › peer-review
Open AccessFile83 Citations (Scopus)94 Downloads (Pure) -
Taxonomic position, antibiotic resistance and virulence factor production by Stenotrophomonas isolates from patients with cystic fibrosis and other chronic respiratory infections
Fluit, A. C., Bayjanov, J. R., Aguilar, M. D., Cantón, R., Elborn, S., Tunney, M. M., Scharringa, J., Benaissa-Trouw, B. J. & Ekkelenkamp, M. B., 12 May 2022, In: BMC Microbiology. 22, 129.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)67 Downloads (Pure) -
Taxonomic position, antibiotic resistance and virulence factors of clinical Achromobacter isolates
Fluit, A. C., Bayjanov, J. R., Aguilar, M. D., Benaissa-Trouw, B., Tunney, M. M., Westreenen, M. V., Meis, J. F., Elborn, J. S., Cantón, R. & Ekkelenkamp, M. B., Jun 2022, In: Frontiers in bioscience (Scholar edition). 14, 2, 12 p., 9.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)53 Downloads (Pure) -
The Effects of Agrimonia pilosa Ledeb, Anemone chinensis Bunge, and Smilax glabra Roxb on Broiler Performance, Nutrient Digestibility, and Gastrointestinal Tract Microorganisms
McMurray, R. L., Ball, M. E. E., Linton, M., Pinkerton, L., Kelly, C., Lester, J., Donaldson, C., Balta, I., Tunney, M. M., Corcionivoschi, N. & Situ, C., May 2022, In: Animals. 12, 9, e1110.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)120 Downloads (Pure) -
The EXIMIOUS project-Mapping exposure-induced immune effects: connecting the exposome and the immunome
Ronsmans, S., Sørig Hougaard, K., Nawrot, T. S., Plusquin, M., Huaux, F., Jesús Cruz, M., Moldovan, H., Verpaele, S., Jayapala, M., Tunney, M., Humblet-Baron, S., Dirven, H., Cecilie Nygaard, U., Lindeman, B., Duale, N., Liston, A., Meulengracht Flachs, E., Kastaniegaard, K., Ketzel, M. & Goetz, J. & 3 others, , 01 Feb 2022, In: Environmental epidemiology (Philadelphia, Pa.). 6, 1, e193.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)56 Downloads (Pure) -
Valaciclovir for Epstein-Barr virus suppression in chronic obstructive pulmonary disease: a randomised controlled trial (EViSCO)
Linden, D., Guo-Parke, H., McKelvey, M., Einarsson, G., Lee, A., Fairley, D., Brown, V., Logan, D., Campbell, C., Singh, D., Tunney, M., McAuley, D., Taggart, C. & Kidney, J., 04 Sept 2022, In: European Respiratory Journal. 60, Suppl 66, 856.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Whole-genome analysis of Haemophilus influenzae strains isolated from persons with cystic fibrosis
Fluit, A. C., Bayjanov, J. R., Benaissa-Trouw, B. J., Rogers, M. R. C., Díez-Aguilar, M., Cantón, R., Tunney, M. M., Elborn, J. S. & Ekkelenkamp, M. B., 25 Aug 2022, In: Journal of Medical Microbiology. 71, 8, 10 p., 001570.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
2021
Anti-biofilm activity of murepavadin against cystic fibrosis Pseudomonas aeruginosa isolates
Díez-Aguilar, M., Ekkelenkamp, M., Morosini, M.-I., Huertas, N., Del Campo, R., Zamora, J., Fluit, A. C., Tunney, M. M., Obrecht, D., Bernardini, F. & Cantón, R., 01 Oct 2021, In: The Journal of antimicrobial chemotherapy. 76, 10, p. 2578-2585 8 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
Changes in sputum bacterial density in people with bronchiectasis: BRONCH UK study data
Alfahl, Z., Einarsson, G. G., O'Neill, K., Gilpin, D. F., Elborn, J. S., Hill, A., Ferguson, K., Loebinger , M. R., Carroll, M., Gatheral, T., de Soyza, A., Johnson, C., Chalmers, J. D., Hurst, J., Brown, J., Bradley, J. M. & Tunney, M. M., 25 Nov 2021, In: European Respiratory Journal. 58, suppl 65Research output: Contribution to journal › Meeting abstract › peer-review
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Characterization of clinical Ralstonia strains and their taxonomic position
Fluit, A. C., Bayjanov, J. R., Aguilar, M. D., Cantón, R., Tunney, M. M., Elborn, J. S., van Westreenen, M. & Ekkelenkamp, M. B., 31 Aug 2021, (Early online date) In: Antonie Van Leeuwenhoek.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)114 Downloads (Pure) -
Development of a core outcome set for clinical trials aimed at improving antimicrobial stewardship in care homes
Nguyen, H. Q., Bradley, D. T., Tunney, M. M. & Hughes, C. M., 09 Mar 2021, In: Antimicrobial Resistance and Infection Control. 10, 52.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)119 Downloads (Pure) -
Efficacy and safety of TOBI Podhaler in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study
Loebinger, M. R., Polverino, E., Chalmers, J. D., Tiddens, H. A. W. M., Goossens, H., Tunney, M., Ringshausen, F. C., Hill, A. T., Pathan, R., Angyalosi, G., Blasi, F., Elborn, S. J. & Haworth, C. S., 05 Jan 2021, In: European Respiratory Journal. 57, 1, 2001451.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
Evolution of levofloxacin resistance and phenotypic characterisation of Pseudomonas aeruginosa clinical isolates from people with cystic fibrosis
Sloan, C. M., Sherrard, L. J., Einarsson, G. G., Tunney, M. M. & Downey, D. G., 01 Jun 2021, In: Journal of Cystic Fibrosis. 20, Supplement 1, p. S84-S85 P149.Research output: Contribution to journal › Meeting abstract › peer-review
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Extended-culture and culture-independent molecular analysis of the airway microbiota in cystic fibrosis following CFTR modulation with ivacaftor
Einarsson, G. G., Ronan, N. J., Mooney, D., McGettigan, C., Mullane, D., NiChroinin, M., Shanahan, F., Murphy, D. M., McCarthy, M., McCarthy, Y., Eustace, J. A., Gilpin, D. F., Elborn, J. S., Plant, B. J. & Tunney, M. M., 04 Feb 2021, (Early online date) In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)238 Downloads (Pure) -
Murepavadin antimicrobial activity against and resistance development in cystic fibrosis Pseudomonas aeruginosa isolates
Díez-Aguilar, M., Hernández-García, M., Morosini, M. I., Fluit, A., Tunney, M. M., Huertas, N., Del Campo, R., Obrecht, D., Bernardini, F., Ekkelenkamp, M. & Cantón, R., 01 Apr 2021, In: Journal of Antimicrobial Chemotherapy. 76, 4, p. 984-992 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
P147: Changes in Pseudomonas aeruginosa phenotypes following the development of tobramycin resistance
McCleave, R. P., Li, Z., Einarsson, G. G., Tunney, M. M., Loebinger, M. R., Chalmers, J. D., Elborn, S. J., Haworth, C. S. & Sherrard, L. J., 01 Jun 2021, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 20, Supplement 1, p. S84 1 p., P147.Research output: Contribution to journal › Meeting abstract › peer-review
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Poster Abstract: EPS3.01 Is variation in Pseudomonas aeruginosa (Pa) surface-enhanced Raman spectroscopy (SERS) spectra related to phenotype?
Allen, D., Einarsson, G. G., Elborn, J. S., Bell, S. & Tunney, M. M., 11 Jun 2021, In: Journal of Cystic Fibrosis. 20, S35, p. S35 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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2020
Antibacterial Activity of Four Plant Extracts Extracted from Traditional Chinese Medicinal Plants against Listeria monocytogenes, Escherichia coli, and Salmonella enterica subsp. enterica serovar Enteritidis
McMurray, R., Ball , E., Tunney, M., Corcionivoschi , N. & Situ, C., 26 Jun 2020, In: Microorganisms. 8, 962, 12 p., 962.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)304 Downloads (Pure) -
Antimicrobial Stewardship in Care Homes: Outcomes of Importance to Stakeholders
Nguyen, H. Q., Bradley, D. T., Tunney, M. M. & Hughes, C. M., 10 Jan 2020, (Early online date) In: The Journal of Hospital Infection.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)303 Downloads (Pure) -
Changes in Lung Clearance Index in the iBEST-1 study
O'Neill, K., Ferguson , K., Cosgrove, D., Chalmers, J. D., Loebinger, M. R., Angyalosi, G., Haworth, C. S., Elborn, J. S., Tunney, M. M. & Bradley, J. M., 16 Dec 2020, In: European Respiratory & Pulmonary Diseases. 6, 1, supp. 2, p. 24-25Research output: Contribution to journal › Meeting abstract › peer-review
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Composition of the airway bacterial community correlates with chest HRCT in adults with bronchiectasis
O'Neill, K., Einarsson, G., Rowan, S., McIlreavey, L., Lee, A., Lawson, J., Lynch, T., Horsley, A., Bradley, J., Elborn, J. & Tunney, M., Jan 2020, In: Respirology. 25, 1, p. 64-70Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)189 Downloads (Pure) -
Developing evidence-based guidance for assessment of suspected infections in care home residents
Hughes, C., Ellard, D. R., Campbell, A., Potter, R., Shaw, C., Gardner, E., Agus, A., O'Reilly, D., Underwood, M., Loeb, M., Stafford, B. & Tunney, M., 14 Feb 2020, In: BMC Geriatrics. 20, 1, p. 59Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)90 Downloads (Pure) -
Draft genome sequence of a haemophilus parainfluenzae strain isolated from a patient with chronic obstructive pulmonary disease
Fluit, A. C., Ekkelenkamp, M. B., Tunney, M. M., Elborn, J. S., Rogers, M. R. C. & Bayjanov, J. R., 26 Mar 2020, In: Microbiology resource announcements. 9, 13, 2 p., e00079-20.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Downloads (Pure)