Research Output per year
Research Output per year
Personal profile
Interests
Dr. Greene completed her PhD within the School of Pharmacy at Queen’s University Belfast, which focused on the therapeutic evaluation of a novel immunomodulatory nanoparticle in models of Acute Respiratory Distress Syndrome. Within her present role as a postdoctoral researcher, Dr. Greene has continued to apply her expertise in nanomedicine, particularly in the field of oncology. She is currently engaged in a US-Ireland R&D Partnership Programme that aims to develop more effective therapies for pancreatic cancer, by combining nanomedicines with agents that can overcome the drug delivery barriers posed by the tumour microenvironment.
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Research Output
- 13 Article
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Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature
Leach, A., Smyth, P., Ferguson, L., Steven, J., Greene, M. K., Branco, C. M., McCann, A. P., Porter, A., Barelle, C. J. & Scott, C. J., 21 Jul 2020, In : Nanoscale. 12, 27, p. 14751-14763 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)17 Downloads (Pure) -
Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer
Greene, M. K., Chen, T., Robinson, E., Straubinger, N. L., Minx, C., Chan, D. K. W., Wang, J., Burrows, J. F., Van Schaeybroeck, S., Baker, J. R., Caddick, S., Longley, D. B., Mager, D. E., Straubinger, R. M., Chudasama, V. & Scott, C. J., 11 Sep 2020, In : British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
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DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models
Johnston, M., Nicoll, J., Redmond, K., Smyth, P., Greene, M., McDaid, W., Crawford, N., Stott, K., Fox, J., Longley, D. & Scott, C., 10 Aug 2020, In : Journal of Controlled Release. 324, p. 610-619 10 p.Research output: Contribution to journal › Article › peer-review
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Refined construction of antibody-targeted nanoparticles leads to superior antigen binding and enhanced delivery of an entrapped payload to pancreatic cancer cells
Greene, M., Nogueira, J., Tracey, S., Richards, D., McDaid, W., Burrows, J., Campbell, K., Longley, D., Chudasama, V. & Scott, C., 14 May 2020, In : Nanoscale.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Oriented attachment of VNAR proteins, via site-selective modification, on PLGA-PEG nanoparticles enhances nanoconjugate performance
Nogueira, J. C. F., Greene, M. K., Richards, D. A., Furby, A. O., Steven, J., Porter, A., Barelle, C., Scott, C. J. & Chudasama, V., 27 Jun 2019, In : Chemical Communications. 55, 53, p. 7671-7674Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)109 Downloads (Pure)