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Interests

Dr. Greene completed her PhD within the School of Pharmacy at Queen’s University Belfast, which focused on the therapeutic evaluation of a novel immunomodulatory nanoparticle in models of Acute Respiratory Distress Syndrome. Within her present role as a postdoctoral researcher, Dr. Greene has continued to apply her expertise in nanomedicine, particularly in the field of oncology. She is currently engaged in a US-Ireland R&D Partnership Programme that aims to develop more effective therapies for pancreatic cancer, by combining nanomedicines with agents that can overcome the drug delivery barriers posed by the tumour microenvironment. 

Fingerprint Dive into the research topics where Michelle Greene is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Nanoparticles Medicine & Life Sciences
glycolic acid Chemical Compounds
Nanoconjugates Chemical Compounds
Sialic Acid Binding Immunoglobulin-like Lectins Medicine & Life Sciences
Klebsiella Infections Medicine & Life Sciences
Ubiquitin-Specific Proteases Medicine & Life Sciences
Tumors Chemical Compounds
Camptothecin Medicine & Life Sciences

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Research Output 2014 2019

1 Citation (Scopus)

Oriented attachment of VNAR proteins, via site-selective modification, on PLGA-PEG nanoparticles enhances nanoconjugate performance

Nogueira, J. C. F., Greene, M. K., Richards, D. A., Furby, A. O., Steven, J., Porter, A., Barelle, C., Scott, C. J. & Chudasama, V., 27 Jun 2019, In : Chemical Communications. 55, 53, p. 7671-7674

Research output: Contribution to journalArticle

Open Access
File
glycolic acid
Nanoconjugates
Antigen Receptors
Lactic acid
Antigens

Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours

McDaid, W. J., Greene, M. K., Johnston, M. C., Pollheimer, E., Smyth, P., McLaughlin, K., Van Schaeybroeck, S., Straubinger, R. M., Longley, D. B. & Scott, C. J., 18 Oct 2019, In : Nanoscale. 13 p.

Research output: Contribution to journalArticle

Chemotherapy
Epidermal Growth Factor Receptor
Antibodies
Tumors
Nanoparticles
3 Citations (Scopus)
Open Access
File
Klebsiella Infections
Klebsiella pneumoniae
Gentamicins
Nanoparticles
Microbial Viability
19 Citations (Scopus)

Generating Next-Generation Antibody-Nanoparticle Conjugates through the Oriented Installation of Non-Engineered Antibody Fragments

Greene, M. K., Richards, D. A., Nogueira, J. C. F., Campbell, K., Smyth, P., Fernańdez, M., Scott, C. J. & Chudasama, V., 14 Aug 2017, In : Chemical Science. 1, p. 79-87 9 p.

Research output: Contribution to journalArticle

Open Access
File
Immunoglobulin Fragments
Nanoparticles
Antibodies
Antibody Binding Sites
Ligands

Encapsulation of the p38 MAPK inhibitor GSK 678361A in nanoparticles for inflammatory‐based disease states

Bains, B., Greene, M. K., McGirr, L., Dorman, J., Farrow, S. & Scott, C., 29 May 2016, In : Journal of Interdisciplinary Nanomedicine. 1, 3, p. 85-92

Research output: Contribution to journalArticle

Open Access
File
p38 Mitogen-Activated Protein Kinases
Protein Kinase Inhibitors
Nanoparticles
Lipopolysaccharides
Anti-Inflammatory Agents