Projects per year
Personal profile
Research Statement
Prof Clarke has 30 years experience in the rigourous evaluation of the effects of health and social care, including numerous randomised trials, systematic reviews and other prospective studies. He has been actively involved in the design, conduct, monitoring and reporting of dozens of randomised trials, including several that have recruited more than 1000 participants (in breast cancer, maternity care, poisoning and sub-arachnoid haemorrhage). He has provided detailed advice for hundreds of other trials, processed and interpreted the individual participant data (IPD) from more than a thousand trials included in systematic reviews, and assessed reports for tens of thousands more as part of initiatives to improve access to research information. His work on systematic reviews includes the collection of IPD from randomised trials across all treatments for women with breast cancer, leading to internationally-renowned reports that influence the care of millions of women worldwide.
Prof Clarke's research, coupled with more than two decades of teaching about randomised trials and systematic reviews (including establishing the relevant modules on the University of Oxford's MSc in Evidence Based Health Care) have provided him with unique insights into the evaluation of health and social care. He is building on this experience when designing and conducting research into research methodoogly, and established the SWAT and SWAR (Studies Within A Trial / Review) initiatives to facilitate this.
Prof Clarke is the Director of the Northern Ireland Clinical Trials Unit and the Northern Ireland Methodology Hub, and Co-ordinating Editor of the Cochrane Methodology Review Group. He has been a leading proponent of the importance of using systematic reviews in the design and reporting of clinical trials for some time, and his work on core outcome sets (as part of the COMET Initiative) also serves to improve the quality and usefulness of trials and reviews. His research reflects his strong interest in increasing the capacity for reviews and trials, and in improving their accessibility, in particular in low- and middle-income countries. He is Podcast Editor for the Cochrane Library and a founder of Evidence Aid, seeking to make it easier to use evidence from reviews in natural disasters and other humanitarian emergencies, and is the charity's Research Director and Chair of the Board of Trustees.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Network
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R2821CPH: ENGINE, STABLE (Eyecare Nurtures Good-health, Innovation, driviNg-safety and Education)
Congdon, N., Azuara-Blanco, A., Chan, V. F., Clarke, M., Lohfeld, L. & O'Neill, C.
13/08/2021 → …
Project: Research
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An umbrella review of the acceptability of fiscal and pricing policies to reduce diet-related noncommunicable disease
Barry, L. E., Kee, F., Woodside, J., Cawley, J., Doherty, E., Clarke, M., Crealey, G. E., Duggan, J. & O'Neill, C., 28 Feb 2023, (Early online date) In: Nutrition Reviews. 22 p., nuad011.Research output: Contribution to journal › Review article › peer-review
Open AccessFile9 Downloads (Pure) -
An umbrella review of the effectiveness of fiscal and pricing policies on food and non-alcoholic beverages to improve health
Barry, L. E., Kee, F., Woodside, J., Clarke, M., Cawley, J., Doherty, E., Crealey, G. E., Duggan, J. & O'Neill, C., 24 Apr 2023, (Early online date) In: Obesity Reviews. 18 p., e13570.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Downloads (Pure) -
Diabetic macular edema and diode subthreshold micropulse laser: A randomized double-masked noninferiority clinical trial
Lois, N., Campbell, C., Waugh, N., Azuara-Blanco, A., Maredza, M., Mistry, H., McAuley, D., Acharya, N., Aslam, T. M., Bailey, C., Chong, V., Downey, L., Eleftheriadis, H., Fatum, S., George, S., Ghanchi, F., Groppe, M., Hamilton, R., Menon, G., Saad, A., & 7 others , Jan 2023, In: Ophthalmology. 130, 1, p. 14-27 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
Establishing healthy eating ‘habits’: a pilot randomised controlled trial of a habit-based dietary intervention following oral rehabilitation for older adults
Watson, S., McCrum, L-A., McGuinness, B., Cardwell, C., Clarke, M., Woodside, J. V., McKenna, G. & McGowan, L., 01 Feb 2023, In: Nutrients. 15, 3, 21 p., 731.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Fiscal and pricing policies related to food and nonalcoholic drinks A review of the evidence
O'Neill, C., Barry, L., Clarke, M., Kee, F. & Woodside, J., 16 May 2023, 236 p.Research output: Book/Report › Commissioned report
Open Access
Activities
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Cochrane Database of Systematic Reviews (Journal)
Mike Clarke (Peer reviewer) & Rohan Anand (Peer reviewer)
2021Activity: Publication peer-review and editorial work types › Publication peer-review
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Involving Men and Boys in Family Planning Webinar Series
Aine Aventin (Chair), Martin Robinson (Organiser), Maria Lohan (Organiser) & Mike Clarke (Organiser)
20 Oct 2020 → 31 Dec 2021Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Supporting advance care planning in dementia palliative care; Evaluation of the family carer decision support intervention
Kevin Brazil (Presenter), Gillian Carter (Advisor), Christopher Cardwell (Advisor), Michael Clarke (Advisor), Peter Hudson (Advisor), K Froggatt (Contributor), Anthony Passmore (Advisor) & G Kernohan (Contributor)
02 Oct 2018 → 05 Oct 2018Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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Cochrane Database of Systematic Reviews (Journal)
Mike Clarke (Peer reviewer) & Rohan Anand (Peer reviewer)
2018Activity: Publication peer-review and editorial work types › Publication peer-review
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COMET workshop, at UK and Ireland Cochrane Contributors' meeting
Mike Clarke (Keynote/plenary speaker)
23 Apr 2015Activity: Participating in or organising an event types › Participation in workshop, seminar, course
Press/Media
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Biggest ever study on child ICU patients reveals major improvements with nurse centred care
Bronagh Blackwood, Danny McAuley, Mike Clarke & Lisa McIlmurray
25/08/2021 → 26/08/2021
4 Media contributions
Press/Media: Research