Murali Shyamsundar

Clinical Senior Lecturer, School of Medicine, Dentistry and Biomedical Sciences
Centre for Experimental Medicine

https://orcid.org/0000-0003-3797-8080

Phone+44 (0)28 9097 6381
EmailMurali.Shyamsundar@qub.ac.uk

Room 02.019 - CEM
United Kingdom

Research output per year

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Personal profile

Research Interests

I am a clinical researcher working as a Consultant in Intensive Care Medicine in the Royal Victoria Hospital Belfast and Senior Lecturer in Queen's University Belfast.

My research programme has two themes; Discovery science and critical care big data.

1. The discovery science theme is focussed on using human in vivo models of infection and inflammation in the pulmonary compartment. I use the inhaled lipopolysaccharide model of pulmonary inflammation and surgical one lung model of inflammation. My current reserach projects in these lines include

a. Prevention HARP 2 study - UK multicentre trial aimed at reducing post-operative pulmonary and cardiac complications

b. SELECT - Understanding the in vivo effects of e-cigarettes

c. Role of T regulatory cells in acute respiratory distress syndrome

Current study in set up is "Hyperoxia mediated lung injury" to study the effect of liberal oxygen on pulmonary inflammation.

I have other grants in submission with a similar focus including the role of lung microbiome in increasing the risk of post-operative pulmonary infections.

I collaborate with the Centre for Experimental Medicine and externally with University of California San Francisco for these projects.

2. The critical care big data theme is focussed on supporting clinicians using real time data analytics. There is also a significant component of behavioural sciences in this theme. I collaborate with ECIT, School for Mathematics and Physics and Centre for Public Health in this theme.

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Projects

1 Finished

R1608CII: MRC P2D 2015 - Accelerating the discovery and development of new medicines for the treatment of Acute Respiratory Distress Syndrome (ARDS) through knowledge exchange

McAuley, D. & Shyamsundar, M.

02/03/2016 → 30/11/2016

Project: Research

Research Output

14 Article
4 Poster
2 Editorial
2 Letter
5 More

Mucoactive agents for acute respiratory failure in the critically ill a systematic review and meta-analysis

Anand, R., McAuley, D. F., Blackwood, B., Yap, C., ONeill, B., Connolly, B., Borthwick, M., Shyamsundar, M., Warburton, J., Meenen, D. V., Paulus, F., Schultz, M. J., Dark, P. & Bradley, J. M., 08 Jun 2020, In : Thorax.

Research output: Contribution to journal › Article

Open Access

File

4 Downloads (Pure)

Mucoactive agent use in adult UK Critical Care Units: a survey of health care professionals’ perception, pharmacists’ description of practice, and point prevalence of mucoactive use in invasively mechanically ventilated patients

MICCS collaborators—Critical Care Pharmacists, 04 May 2020, In : PeerJ. 8, 12 p., e8828.

Research output: Contribution to journal › Article

Open Access

File

2 Downloads (Pure)

The weekend effect in status epilepticus: a national cohort study

Goulden, R., Whitehouse, T., Murphy, N., Hayton, T., Khan, Z., Shyamsundar, M., Gao-Smith, F., Snelson, C., Bion, J. & Veenith, T., 03 Jan 2019, In : Anaesthesia.

Research output: Contribution to journal › Article

Open Access

File