Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

I am a clinical researcher working as a Consultant in Intensive Care Medicine in the Royal Victoria Hospital Belfast and Senior Lecturer in Queen's University Belfast.


My research programme has two themes; Discovery science and critical care big data.


1. The discovery science theme is focussed on using human in vivo models of infection and inflammation in the pulmonary compartment. I use the inhaled lipopolysaccharide model of pulmonary inflammation and surgical one lung model of inflammation. My current reserach projects in these lines include

a. Prevention HARP 2 study - UK multicentre trial aimed at reducing post-operative pulmonary and cardiac complications

b. SELECT - Understanding the in vivo effects of e-cigarettes

c. Role of T regulatory cells in acute respiratory distress syndrome

Current study in set up is "Hyperoxia mediated lung injury" to study the effect of liberal oxygen on pulmonary inflammation.

I have other grants in submission with a similar focus including the role of lung microbiome in increasing the risk of post-operative pulmonary infections.

I collaborate with the Centre for Experimental Medicine and externally with University of California San Francisco for these projects.

2. The critical care big data theme is focussed on supporting clinicians using real time data analytics. There is also a significant component of behavioural sciences in this theme. I collaborate with ECIT, School for Mathematics and Physics and Centre for Public Health in this theme.

Fingerprint Dive into the research topics where Murali Shyamsundar is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 39 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.


Research Output

Mucoactive agents for acute respiratory failure in the critically ill a systematic review and meta-analysis

Anand, R., McAuley, D. F., Blackwood, B., Yap, C., ONeill, B., Connolly, B., Borthwick, M., Shyamsundar, M., Warburton, J., Meenen, D. V., Paulus, F., Schultz, M. J., Dark, P. & Bradley, J. M., 08 Jun 2020, In : Thorax.

Research output: Contribution to journalArticle

Open Access
  • 4 Downloads (Pure)
    Open Access
  • 2 Downloads (Pure)

    The weekend effect in status epilepticus: a national cohort study

    Goulden, R., Whitehouse, T., Murphy, N., Hayton, T., Khan, Z., Shyamsundar, M., Gao-Smith, F., Snelson, C., Bion, J. & Veenith, T., 03 Jan 2019, In : Anaesthesia.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Citation (Scopus)
    64 Downloads (Pure)
    Open Access
  • 2 Citations (Scopus)
    134 Downloads (Pure)
    Open Access
  • 1 Citation (Scopus)
    194 Downloads (Pure)


    • 1 Participation in conference

    UK Critical Care Research Forum

    Cecilia O'Kane (Organiser), , Murali Shyamsundar (Organiser), , Bronagh Blackwood (Organiser), & Danny McAuley (Organiser)

    07 Jun 201808 Jun 2018

    Activity: Participating in or organising an event typesParticipation in conference