• Room 02.019 - WWIEM Block 6 MBC Site

    United Kingdom

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Personal profile

Research Interests

I am a clinical researcher working as a Consultant in Intensive Care Medicine in the Royal Victoria Hospital Belfast and Senior Lecturer in Queen's University Belfast.


My research programme has two themes; Discovery science and critical care big data.


1. The discovery science theme is focussed on using human in vivo models of infection and inflammation in the pulmonary compartment. I use the inhaled lipopolysaccharide model of pulmonary inflammation and surgical one lung model of inflammation. My current reserach projects in these lines include

a. Prevention HARP 2 study - UK multicentre trial aimed at reducing post-operative pulmonary and cardiac complications

b. SELECT - Understanding the in vivo effects of e-cigarettes

c. Role of T regulatory cells in acute respiratory distress syndrome

Current study in set up is "Hyperoxia mediated lung injury" to study the effect of liberal oxygen on pulmonary inflammation.

I have other grants in submission with a similar focus including the role of lung microbiome in increasing the risk of post-operative pulmonary infections.

I collaborate with the Centre for Experimental Medicine and externally with University of California San Francisco for these projects.

2. The critical care big data theme is focussed on supporting clinicians using real time data analytics. There is also a significant component of behavioural sciences in this theme. I collaborate with ECIT, School for Mathematics and Physics and Centre for Public Health in this theme.

Fingerprint Dive into the research topics where Murali Shyamsundar is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Acute Lung Injury Medicine & Life Sciences
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Lipopolysaccharides Medicine & Life Sciences
Pneumonia Medicine & Life Sciences
Bronchoalveolar Lavage Medicine & Life Sciences
Randomized Controlled Trials Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2008 2019

The weekend effect in status epilepticus: a national cohort study

Goulden, R., Whitehouse, T., Murphy, N., Hayton, T., Khan, Z., Shyamsundar, M., Gao-Smith, F., Snelson, C., Bion, J. & Veenith, T., 03 Jan 2019, In : Anaesthesia.

Research output: Contribution to journalArticle

Status Epilepticus
Cohort Studies
Critical Care
Odds Ratio
1 Citation (Scopus)
Open Access
Intensive care units
Intensive Care Units
Confidence Intervals
Open Access
One-Lung Ventilation
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Randomized Controlled Trials
Ambulatory Surgical Procedures

Activities 2018 2018

  • 1 Participation in conference

UK Critical Care Research Forum

Cecilia O'Kane (Organiser), Murali Shyamsundar (Organiser), Bronagh Blackwood (Organiser), Danny McAuley (Organiser)
07 Jun 201808 Jun 2018

Activity: Participating in or organising an event typesParticipation in conference