Projects per year
I am a clinical researcher working as a Consultant in Intensive Care Medicine in the Royal Victoria Hospital Belfast and Senior Lecturer in Queen's University Belfast.
My research programme has two themes; Discovery science and critical care big data.
1. The discovery science theme is focussed on using human in vivo models of infection and inflammation in the pulmonary compartment. I use the inhaled lipopolysaccharide model of pulmonary inflammation and surgical one lung model of inflammation. My current reserach projects in these lines include
a. Prevention HARP 2 study - UK multicentre trial aimed at reducing post-operative pulmonary and cardiac complications
b. SELECT - Understanding the in vivo effects of e-cigarettes
c. Role of T regulatory cells in acute respiratory distress syndrome
Current study in set up is "Hyperoxia mediated lung injury" to study the effect of liberal oxygen on pulmonary inflammation.
I have other grants in submission with a similar focus including the role of lung microbiome in increasing the risk of post-operative pulmonary infections.
I collaborate with the Centre for Experimental Medicine and externally with University of California San Francisco for these projects.
2. The critical care big data theme is focussed on supporting clinicians using real time data analytics. There is also a significant component of behavioural sciences in this theme. I collaborate with ECIT, School for Mathematics and Physics and Centre for Public Health in this theme.
Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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R4903CEM: Mucoactive drugs for acute respiratory failure: A 2x2 factorial, randomised, controlled, allocation concealed, open-label, Phase 3, pragmatic, clinical and cost effectiveness trial with internal pilot
24/07/2020 → …
Gillan, C., Hagan, R. & Shyamsundar, M., 25 Jan 2021, (Accepted) Technologies and Applications for Big Data Value. Springer
Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
High-flow nasal cannula therapy for initial oxygen administration in acute hypercapnic respiratory failure: study protocol of randomised controlled unblinded trialAlnajada, A., Blackwood, B., Mobrad, A., Akhtar, A. & Shyamsundar, M., 08 Jan 2021, In: BMJ Open Respiratory Research. 8, 1, 8 p., e000853.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile17 Downloads (Pure)
Alnajada, A. A. R., Blackwood, B., Shyamsundar, M., Almobrad, A. & Akhter, Feb 2021.
Research output: Contribution to conference › Poster › peer-review
Airway clearance techniques and use of mucoactive agents for adult critically ill patients with acute respiratory failure: a qualitative study exploring UK physiotherapy practiceConnolly, B., Barclay, M., Blackwood, B., Bradley, J., Anand, R., Borthwick, M., Chikhani, M., Dark, P., Shyamsundar, M., Warburton, J., McAuley, D. F. & O'Neill, B., 01 Sep 2020, In: Physiotherapy (United Kingdom). 108, p. 78-87 10 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile49 Downloads (Pure)
Comparing regression and neural network techniques for personalized predictive analytics to promote lung protective ventilation in Intensive Care UnitsHagan, R., Gillan, C., Spence, I., McAuley, D. & Shyamsundar, M., 01 Nov 2020, In: Computers in Biology and Medicine. 126
Research output: Contribution to journal › Article › peer-review
Mucoactive agent use in adult UK Critical Care Units: a survey of health care professionals perception, pharmacists’ description of practice, and point prevalence of mucoactive use in invasively mechanically ventilated patients
Shyamsundar, M. (Creator), Queen's University Belfast, 30 Aug 2019