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    United Kingdom

Accepting PhD Students

20052019
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Personal profile

Research Statement

Dr Niamh Buckley graduated from Trinity College, Dublin in 2002 with a First Class Honours Degree in Biochemistry.  She then carried out her Ph.D. training in the Department of Oncology (Queen’s University Belfast) under the supervision of Prof. Paul Harkin.  Following this, she then worked as a post-doctoral researcher with Dr Paul Mullan in the Centre for Cancer Research and Cell Biology (Queen’s University Belfast).  During this time she investigated the role of the breast and ovarian tumour suppressor gene, BRCA1, in stem cell regulation and mammary gland differentiation.

Dr Buckley was awarded the prestigious Breast Cancer Now fellowship in 2013 to develop novel biomarkers and therapeutic strategies in BRCA1-mutant and/or triple negative breast cancer.  In 2016 she was appointed as a Lecturer in Personalised Medicine and Pharmacogenomics in the School of Pharmacy (Queen’s University Belfast).  Her research focuses on the integration of in vitro, in vivo, bioinformatics and pathology approaches to identify key pathways underpinning poor outcome breast cancer and use detailed knowledge of this biology to identify appropriate targeted treatment options, personalising therapy in an area of unmet clinical need.

 

Achievements

Dr Buckley’s work has led to a number of significant publications in leading cancer research journals and she has been the recipient of several prestigious awards including European Association of Cancer Research (EACR) Young Scientist Award (2012), Roche Gold Medal Award (2011) and School of Medicine, Dentistry and Biomedical Sciences Post-Doctoral Researcher of the Year (2012).

Research Interests

Breast Cancer

Triple Negative Breast Cancer

BRCA1

Ovarian Cancer

Personalised Medicine

Targeted Treatments

Biomarkers

Teaching

Contributes to the following modules:

MPharm Degree

PMY3176 Advanced Delivery Systems for Large and Small Molecules (Module Co-ordinator)

PMY4005 Research Project

PMY4107 Advanced Pharmaceutical Care

BSc Pharmaceutical Sciences

PMY2021 Principles of Drug Action

PMY3176  Advanced Delivery Systems for Large and Small Molecules (Module Co-ordinator)

BSc Pharmaceutical Biotechnology

PMY2021 Principles fo Drug Action

PMY2026 Biochemistry and Molecular Biology

PMY3027 Applied Biotechnology and Regulatory Affairs (Module Co-ordinator)

PMY3028 Biological Approaches to Disease Prevention and Treatment

Distance Learning Supervisor

PG Diploma in Clinical Pharmacy

MSc Clinical Pharmacy

 

Postgraduate Courses within SMDBS

MSc(Res) Cancer Medicine

MSc Molecular Pathology of Cancer

 

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  • 61 Similar Profiles
Triple Negative Breast Neoplasms Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Biomarkers Medicine & Life Sciences
Breast Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
cathepsin S Medicine & Life Sciences
Ovarian Neoplasms Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2019

A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer

Wilkinson, R., Burden, R., McDowell, S., McArt, D., McQuaid, S., Bingham, V., Williams, R., Cox, O., O'Connor, R., McCabe, N., Kennedy, R., Buckley, N. E. & Scott, C., 28 Jun 2019, In : Journal of Oncology.

Research output: Contribution to journalArticle

Open Access
File
cathepsin S
Triple Negative Breast Neoplasms
Biomarkers
Neoplasms
DNA Repair

Defining the molecular evolution of extrauterine high grade serous carcinoma

Beirne, J. P., McArt, D. G., Roddy, A., McDermott, C., Ferris, J., Buckley, N. E., Coulter, P., McCabe, N., Eddie, S. L., Dunne, P. D., O'Reilly, P., Gilmore, A., Feeney, L., Ewing, D. L., Drapkin, R. I., Salto-Tellez, M., Kennedy, R. D., Harley, I. J. G., McCluggage, W. G. & Mullan, P. B., 04 Sep 2019, In : Gynecologic Oncology. 155, 2, p. 305-317 13 p.

Research output: Contribution to journalArticle

Molecular Evolution
Carcinoma
Fallopian Tubes
Carcinoma in Situ
Epithelium

Exploring the Potential of MicroRNA Let-7c as a Therapeutic for Prostate Cancer

Mulholland, E. J., Green, W. P., Buckley, N. E. & McCarthy, H. O., 22 Oct 2019, In : Molecular Therapy: Nucleic Acids. 18, p. 927-937 11 p.

Research output: Contribution to journalReview article

Open Access
File
MicroRNAs
Prostatic Neoplasms
Databases
Therapeutics
Neoplasms
1 Citation (Scopus)

NUP98 – a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer

Mullan, P. B., Bingham, V., Haddock, P., Irwin, G. W., Kay, E., McQuaid, S. & Buckley, N. E., 02 Apr 2019, In : BMC Cancer. 19, 13 p., 236.

Research output: Contribution to journalArticle

Open Access
File
Triple Negative Breast Neoplasms
Anthracyclines
Drug Therapy
Standard of Care
Biomarkers
1 Citation (Scopus)

PDLIM2 is a marker of adhesion and β-catenin activity in triple-negative breast cancer

Cox, O., Edmunds, S., Simon-Keller, K., Li, B., Moran, B., Buckley, N. E., Bustamante-Garrido, M., Healy, N., O'Flanagan, C. H., Gallagher, W. M., Kennedy, R., Bernards, R., Caldos, C., Chin, S-F., Marx, A. & O'Connor, R., 18 Mar 2019, In : Cancer Research.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
beta Catenin
Phenotype
Neoplasms
Cytoplasm

Prizes

All Ireland Researcher of the Year

Niamh Buckley (Recipient), 2012

Prize: Prize (including medals and awards)

applied science

CCRCB Researcher of the Year

Niamh Buckley (Recipient), 2012

Prize: Prize (including medals and awards)

JD Williamson Prize for Research

Niamh Buckley (Recipient), 2011

Prize: Prize (including medals and awards)

Keystone Travel Award

Niamh Buckley (Recipient), 2004

Prize: Prize (including medals and awards)

Oral Presentation Award

Niamh Buckley (Recipient), 2004

Prize: Prize (including medals and awards)

Activities 2004 2019

Where we are and where we are going: The winding road of Cancer Immunotherapy Biomarkers

Niamh Buckley (Invited speaker)
09 Aug 2019

Activity: Talk or presentation typesInvited talk

Pathology Horizons

Niamh Buckley (Session chair)
09 Aug 2019

Activity: Participating in or organising an event typesParticipation in conference

World CB and CDx Conference

Niamh Buckley (Participant)
15 Apr 201916 Apr 2019

Activity: Participating in or organising an event typesParticipation in conference

Irish Association for Cancer Research Annual Meeting 2019

Niamh Buckley (Session chair)
22 Feb 2019

Activity: Participating in or organising an event typesParticipation in conference

BRCALinkNI Annual Information day 2019

Niamh Buckley (Organiser)
01 Feb 2019

Activity: Participating in or organising an event typesParticipation in conference

Press / Media

Asda staff in the pink!

Niamh Buckley

10/10/2018

1 item of media coverage

Press/Media: Public Engagement Activities

Tickled Pink donations are helping to fund pioneering breast cancer research

Niamh Buckley

09/10/2018

1 item of media coverage

Press/Media: Public Engagement Activities

Asda Larne ‘in the pink’ for Breast Cancer Awareness Month

Niamh Buckley

03/10/2018

1 item of media coverage

Press/Media: Public Engagement Activities

Asda colleagues in Northern Ireland get ‘Tickled Pink’ for Breast Cancer Awareness Month

Niamh Buckley

03/10/2018

1 item of media coverage

Press/Media: Public Engagement Activities

Beating breast cancer with gene testing on the rise

Niamh Buckley

14/03/2018

1 item of media coverage

Press/Media: Public Engagement Activities