• Room 06.019 - Medical Biology Centre

    United Kingdom

Accepting PhD Students

PhD projects

Open to PhD applications in the field of cancer research, personalised medicine, biomarkers and novel treatment options.

20052020

Research output per year

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Personal profile

Research Statement

Dr Niamh Buckley graduated from Trinity College, Dublin in 2002 with a First Class Honours Degree in Biochemistry.  She then carried out her Ph.D. training in the Department of Oncology (Queen’s University Belfast) under the supervision of Prof. Paul Harkin.  Following this, she then worked as a post-doctoral researcher with Dr Paul Mullan in the Centre for Cancer Research and Cell Biology (Queen’s University Belfast).  During this time she investigated the role of the breast and ovarian tumour suppressor gene, BRCA1, in stem cell regulation and mammary gland differentiation.

Dr Buckley was awarded the prestigious Breast Cancer Now fellowship in 2013 to develop novel biomarkers and therapeutic strategies in BRCA1-mutant and/or triple negative breast cancer.  In 2016 she was appointed as a Lecturer in Personalised Medicine and Pharmacogenomics in the School of Pharmacy (Queen’s University Belfast).  Her research focuses on the integration of in vitro, in vivo, bioinformatics and pathology approaches to identify key pathways underpinning poor outcome breast cancer and use detailed knowledge of this biology to identify appropriate targeted treatment options, personalising therapy in an area of unmet clinical need.

 

Achievements

Dr Buckley’s work has led to a number of significant publications in leading cancer research journals and she has been the recipient of several prestigious awards including European Association of Cancer Research (EACR) Young Scientist Award (2012), Roche Gold Medal Award (2011) and School of Medicine, Dentistry and Biomedical Sciences Post-Doctoral Researcher of the Year (2012).

Research Interests

Breast Cancer

Triple Negative Breast Cancer

BRCA1

Ovarian Cancer

Personalised Medicine

Targeted Treatments

Biomarkers

Teaching

Contributes to the following modules:

MPharm Degree

PMY3176 Advanced Delivery Systems for Large and Small Molecules (Module Co-ordinator)

PMY4005 Research Project

PMY4107 Advanced Pharmaceutical Care

BSc Pharmaceutical Sciences

PMY2021 Principles of Drug Action

PMY3176  Advanced Delivery Systems for Large and Small Molecules (Module Co-ordinator)

BSc Pharmaceutical Biotechnology

PMY2021 Principles fo Drug Action

PMY2026 Biochemistry and Molecular Biology

PMY3027 Applied Biotechnology and Regulatory Affairs (Module Co-ordinator)

PMY3028 Biological Approaches to Disease Prevention and Treatment

Distance Learning Supervisor

PG Diploma in Clinical Pharmacy

MSc Clinical Pharmacy

 

Postgraduate Courses within SMDBS

MSc(Res) Cancer Medicine

MSc Molecular Pathology of Cancer

 

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Research Output

Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation

Haughey, C. M., Mukherjee, D., Steele, R. E., Popple, A., Dura-Perez, L., Pickard, A., Jain, S., Mullan, P. B., Williams, R., Oliveira, P., Buckley, N. E., Honeychurch, J., Williams, R., McDade, S., Illidge, T., Mills, I. G. & Eddie, S. L., 2020

Research output: Other contribution

Open Access
  • Open Access
  • A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer

    Wilkinson, R., Burden, R., McDowell, S., McArt, D., McQuaid, S., Bingham, V., Williams, R., Cox, O., O'Connor, R., McCabe, N., Kennedy, R., Buckley, N. E. & Scott, C., 28 Jun 2019, In : Journal of Oncology.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 78 Downloads (Pure)

    Defining the molecular evolution of extrauterine high grade serous carcinoma

    Beirne, J. P., McArt, D. G., Roddy, A., McDermott, C., Ferris, J., Buckley, N. E., Coulter, P., McCabe, N., Eddie, S. L., Dunne, P. D., O'Reilly, P., Gilmore, A., Feeney, L., Ewing, D. L., Drapkin, R. I., Salto-Tellez, M., Kennedy, R. D., Harley, I. J. G., McCluggage, W. G. & Mullan, P. B., 04 Sep 2019, In : Gynecologic Oncology. 155, 2, p. 305-317 13 p.

    Research output: Contribution to journalArticle

  • Exploring the Potential of MicroRNA Let-7c as a Therapeutic for Prostate Cancer

    Mulholland, E. J., Green, W. P., Buckley, N. E. & McCarthy, H. O., 22 Oct 2019, In : Molecular Therapy: Nucleic Acids. 18, p. 927-937 11 p.

    Research output: Contribution to journalReview article

    Open Access
    File
  • Prizes

    All Ireland Researcher of the Year

    Niamh Buckley (Recipient), 2012

    Prize: Prize (including medals and awards)

  • CCRCB Researcher of the Year

    Niamh Buckley (Recipient), 2012

    Prize: Prize (including medals and awards)

    JD Williamson Prize for Research

    Niamh Buckley (Recipient), 2011

    Prize: Prize (including medals and awards)

    Keystone Travel Award

    Niamh Buckley (Recipient), 2004

    Prize: Prize (including medals and awards)

    Oral Presentation Award

    Niamh Buckley (Recipient), 2004

    Prize: Prize (including medals and awards)

    Activities

    Impact from Breast Cancer Research

    Niamh Buckley (Invited speaker)
    18 Sep 2019

    Activity: Talk or presentation typesInvited talk

    Personalised Medicine: Triple Negative Breast Cancer

    Niamh Buckley (Invited speaker)
    11 Nov 2019

    Activity: Talk or presentation typesInvited talk

    Irish Association for Cancer Research Annual Meeting 2019

    Niamh Buckley (Member of programme committee)
    20 Feb 201922 Feb 2019

    Activity: Participating in or organising an event typesParticipation in conference

    World CB and CDx Conference

    Niamh Buckley (Participant)
    15 Apr 201916 Apr 2019

    Activity: Participating in or organising an event typesParticipation in conference

    Irish Association for Cancer Research Annual Meeting 2019

    Niamh Buckley (Session chair)
    22 Feb 2019

    Activity: Participating in or organising an event typesParticipation in conference

    Press / Media

    Asda staff in the pink!

    Niamh Buckley

    10/10/2018

    1 item of Media coverage

    Press/Media: Public Engagement Activities

    Tickled Pink donations are helping to fund pioneering breast cancer research

    Niamh Buckley

    09/10/2018

    1 item of Media coverage

    Press/Media: Public Engagement Activities

    Asda Larne ‘in the pink’ for Breast Cancer Awareness Month

    Niamh Buckley

    03/10/2018

    1 item of Media coverage

    Press/Media: Public Engagement Activities

    Asda colleagues in Northern Ireland get ‘Tickled Pink’ for Breast Cancer Awareness Month

    Niamh Buckley

    03/10/2018

    1 item of Media coverage

    Press/Media: Public Engagement Activities

    Beating breast cancer with gene testing on the rise

    Niamh Buckley

    14/03/2018

    1 item of Media coverage

    Press/Media: Public Engagement Activities