Projects per year
Personal profile
Research Statement
Dr Niamh Buckley graduated from Trinity College, Dublin in 2002 with a First Class Honours Degree in Biochemistry. She then carried out her Ph.D. training in the Department of Oncology (Queen’s University Belfast) under the supervision of Prof. Paul Harkin. Following this, she then worked as a post-doctoral researcher with Dr Paul Mullan in the Centre for Cancer Research and Cell Biology (Queen’s University Belfast). During this time, she investigated the role of the breast and ovarian tumour suppressor gene, BRCA1, in stem cell regulation and mammary gland differentiation.
Dr Buckley was awarded the prestigious Breast Cancer Now fellowship in 2013 to develop novel biomarkers and therapeutic strategies in BRCA1-mutant and/or triple negative breast cancer. In 2016 she was appointed as a Lecturer in Personalised Medicine and Pharmacogenomics in the School of Pharmacy (Queen’s University Belfast). She was then promoted to Senior Lecturer in 2020 and is an active member of the Nanomedicine and Biotherapeutics Cluster. Dr Buckley is also an associate member of the Patrick G Johnson Centre for Cancer Research (PGJCCR) at QUB. Her research focuses on the integration of in vitro, in vivo, bioinformatics and pathology approaches to identify key pathways underpinning poor outcome breast cancer and use detailed knowledge of this biology to identify appropriate targeted treatment options, personalising therapy in an area of unmet clinical need.
Achievements
Dr Buckley has secured ~£5 million in competitive grant income from national and international funding boards in the last 2 years with >£750,000 as PIand has published in over 30 articles in leading Q1 journals with over 1100 citations. Her knowledge and expertise have been recognised by invitations to speak at national and international conferences and membership of the Breast Cancer Now Grant Review Committee and Tissue Access Committee. She has also been the recipient of several prestigious awards including European Association of Cancer Research (EACR) Young Scientist Award (2012), Roche Gold Medal Award (2011) and School of Medicine, Dentistry and Biomedical Sciences Post-Doctoral Researcher of the Year (2012).
Research Interests
Breast Cancer
Triple Negative Breast Cancer
BRCA1
Ovarian Cancer
Personalised Medicine
Targeted Treatments
Biomarkers
Teaching
Contributes to the following modules:
MPharm Degree
PMY3176 Advanced Delivery Systems for Large and Small Molecules (Module Co-ordinator)
PMY4005 Research Project
PMY4107 Advanced Pharmaceutical Care
BSc Pharmaceutical Sciences
PMY2021 Principles of Drug Action
PMY3176 Advanced Delivery Systems for Large and Small Molecules (Module Co-ordinator)
BSc Pharmaceutical Biotechnology
PMY2021 Principles fo Drug Action
PMY2026 Biochemistry and Molecular Biology
PMY3027 Applied Biotechnology and Regulatory Affairs (Module Co-ordinator)
PMY3028 Biological Approaches to Disease Prevention and Treatment
Distance Learning Supervisor
PG Diploma in Clinical Pharmacy
MSc Clinical Pharmacy
Postgraduate Courses within SMDBS
MSc(Res) Cancer Medicine
MSc Molecular Pathology of Cancer
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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R2652CNR: High Parameter Flow Cytometry in Health and Disease - Full application
Small, D. (PI), Buckley, N. (CoI), Fitzgerald, D. (CoI), Guzman de la Fuente, A. (CoI), Ingram, B. (CoI), Kerr, E. (CoI) & Longley, D. (CoI)
28/10/2019 → 29/09/2025
Project: Research
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A five-biomarker IHC-based signature predicting outcome in breast cancer patients following adjuvant anthracycline-based chemotherapy
Wang, S., Gilmore, E., Umbreen, S., Fines, C., Burden, R., McQuaid, S. & Buckley, N., Apr 2026, In: Cancers. 18, 7, 21 p., 1092.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Chemotherapeutics as immune modulators for the treatment of triple-negative breast cancer
Fines, C. B., Kelly, S., McCarthy, H. O. & Buckley, N. E., 09 May 2026, In: Cancers. 18, 10, 17 p., 1537.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Downloads (Pure) -
Development of a nano-vaccine for high-grade serous ovarian cancer
Saha, C., Elkashif, A., Gilmore, E. J., Jiang, B., Sun, Y., Duary, R. K., Buckley, N., Dunne, N. J. & McCarthy, H. O., 07 Jun 2025, In: Biomaterials Science. 13, 11, p. 2908-2924 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)18 Downloads (Pure) -
Exploring the prognostic and predictive potential of bacterial biomarkers in non-gastrointestinal solid tumors
Burke, C., Glynn, T., Jahangir, C., Murphy, C., Buckley, N., Tangney, M., Rahman, A. & Gallagher, W. M., 26 Feb 2025, In: Expert Review of Molecular Diagnostics. 25, 4, p. 117-128 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Link opens in a new tab Citations (Scopus)115 Downloads (Pure) -
The immunomodulatory role of gemcitabine in triple negative breast cancer
Fines, C., Umbreen, S., Gilmore, E., McCarthy, H. & Buckley, N., 16 Oct 2025, In: Cells. 14, 20Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)19 Downloads (Pure)
Prizes
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All Ireland Researcher of the Year
Buckley, N. (Recipient), 2012
Prize: Prize (including medals and awards)
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JD Williamson Prize for Research
Buckley, N. (Recipient), 2011
Prize: Prize (including medals and awards)
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Activities
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NI Genetics:
Buckley, N. (Advisor)
14 May 2026Activity: Talk or presentation types › Public lecture/debate/seminar
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PhD External Examiner
Buckley, N. (Examiner)
Dec 2025Activity: Examination types › PhD external examination
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PhD External Examiner
Buckley, N. (Examiner)
Jun 2025Activity: Examination types › PhD external examination
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Cancer Nanotechnology (Journal)
Buckley, N. (Peer reviewer)
2025 → …Activity: Publication peer-review and editorial work types › Publication peer-review
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External Examiner
Buckley, N. (Examiner)
2025 → 2028Activity: Examination types › UG external examination
Press/Media
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Personalized mRNA Vaccine Spurs Lasting Immunity in TNBC
27/02/2026
1 Media contribution
Press/Media: Expert Comment
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Asda Celebrating 20 years in NI
17/10/2025
1 item of Media coverage
Press/Media: Public Engagement Activities
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The test that told me a gum infection caused my breast cancer
22/09/2024
1 Media contribution
Press/Media: Expert Comment
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A new jab may prevent my daughter suffering breast cancer like I did
20/07/2023
1 Media contribution
Press/Media: Expert Comment