Nick Orr

Dr

  • Room 01.003 - CCRCB

    United Kingdom

Accepting PhD Students

PhD projects

Dr Orr is open to wide-ranging PhD applications from candidates with a basic science or clinical background. His fields of interest include: - genetic epidemiology of cancer - biological mechanisms of cancer predisposition - functional genomics Previous research experience is desirable although not essential.

20062020

Research output per year

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  • A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

    Escala-Garcia, M., Abraham, J., Andrulis, I. L., Anton-Culver, H., Arndt, V., Ashworth, A., Auer, P. L., Auvinen, P., Beckmann, M. W., Beesley, J., Behrens, S., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Børresen-Dale, A-L., Brauch, H. & 125 others, Brenner, H., Brucker, S. Y., Burwinkel, B., Caldas, C., Canzian, F., Chang-Claude, J., Chanock, S. J., Chin, S-F., Clarke, C. L., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Dennis, J., Devilee, P., Dunn, J. A., Dunning, A. M., Dwek, M., Earl, H. M., Eccles, D. M., Eliassen, A. H., Ellberg, C., Evans, D. G., Fasching, P. A., Figueroa, J., Flyger, H., Gago-Dominguez, M., Gapstur, S. M., García-Closas, M., García-Sáenz, J. A., Gaudet, M. M., George, A., Giles, G. G., Goldgar, D. E., González-Neira, A., Grip, M., Guénel, P., Guo, Q., Haiman, C. A., Håkansson, N., Hamann, U., Harrington, P. A., Hiller, L., Hooning, M. J., Hopper, J. L., Howell, A., Huang, C-S., Huang, G., Hunter, D. J., Jakubowska, A., John, E. M., Kaaks, R., Kapoor, P. M., Keeman, R., Kitahara, C. M., Koppert, L. B., Kraft, P., Kristensen, V. N., Lambrechts, D., Le Marchand, L., Lejbkowicz, F., Lindblom, A., Lubiński, J., Mannermaa, A., Manoochehri, M., Manoukian, S., Margolin, S., Martinez, M. E., Maurer, T., Mavroudis, D., Meindl, A., Milne, R. L., Mulligan, A. M., Neuhausen, S. L., Nevanlinna, H., Newman, W. G., Olshan, A. F., Olson, J. E., Olsson, H., Orr, N., Peterlongo, P., Petridis, C., Prentice, R. L., Presneau, N., Punie, K., Ramachandran, D., Rennert, G., Romero, A., Sachchithananthan, M., Saloustros, E., Sawyer, E. J., Schmutzler, R. K., Schwentner, L., Scott, C., Simard, J., Sohn, C., Southey, M. C., Swerdlow, A. J., Tamimi, R. M., Tapper, W. J., Teixeira, M. R., Terry, M. B., Thorne, H., Tollenaar, R. A. E. M., Tomlinson, I., Troester, M. A., Truong, T., Turnbull, C., Vachon, C. M., van der Kolk, L. E., Wang, Q., Winqvist, R., Wolk, A., Yang, X. R., Ziogas, A., Pharoah, P. D. P., Hall, P., Wessels, L. F. A., Chenevix-Trench, G., Bader, G. D., Dörk, T., Easton, D. F., Canisius, S. & Schmidt, M. K., 16 Jan 2020, In : Nature Communications. 11, 1, p. 312

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    9 Citations (Scopus)
    22 Downloads (Pure)
  • Assessment of structural chromosomal instability phenotypes as biomarkers of carboplatin response in Triple Negative Breast Cancer: the TNT trial

    Sipos, O., Tovey, H., Quist, J., Haider, S., Nowinski, S., Gazinska, P., Kernaghan, S., Toms, C., Maguire, S., Orr, N., Linn, S., Owen, J., Gillet, C., Pinder, S., Bliss, J., Tutt, A., Cheang, M. & Grigoriadis, A., 20 Oct 2020, In : Annals of Oncology.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Combined associations of a polygenic risk score and classical risk factors with breast cancer risk

    ABCTB Investigators, 02 May 2020, In : Journal of the National Cancer Institute.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    35 Downloads (Pure)
  • Common susceptibility loci for male breast cancer

    Maguire, S., Perrakis, E., Tomczyk, K., Jones, M., Fletcher, O., Pugh, M., Winter, T., Thompson, K., Cooke, R., Trainer, A. H., Paul, J., Bojesen, S. E., Flyger, H., Nevanlinna, H., Mattson, J., Friedman, E., Laitman, Y., Palli, D., Masala, G., Zanna, I. & 23 others, Ottini, L., Silvestri, V., Hollestelle, A., Hooning, M. J., Novaković, S., Krajc, M., Gago-Dominguez, M., Castelao, J. E., Olsson, H., Hedenfalk, I., Saloustros, E., Georgoulias, V., Easton, D. F., Pharoah, P., Dunning, A. M., Timothy Bishop, D., Neuhausen, S. L., Steele, L., Ashworth, A., García-Closas, M., Houlston, R., Swerdlow, A. J. & Orr, N., 12 Aug 2020, In : Journal of the National Cancer Institute.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    74 Downloads (Pure)
  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

    GEMO Study Collaborators, 07 Jan 2020, In : Nature Genetics. 52, 1, p. 56-73

    Research output: Contribution to journalArticlepeer-review

    14 Citations (Scopus)
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