Projects per year
Personal profile
Research Interests
Bio sketch: Noemi Lois, MD, PhD, FRCS(Ed), FRCOphth
Noemi Lois is a Clinical Professor of Ophthalmology at Queens University and an Honorary Consultant Ophthalmologist and Vitreoretinal Surgeon at the Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
After finishing her training in Ophthalmology she completed clinical fellowships in 1) Ocular Oncology at Wills Eye Hospital, Philadelphia, with Drs Jerry and Carol Shields, 2) Medical Retina at Moorfields Eye Hospital, London, with Prof Alan Bird, and 3) Vitreoretinal Surgery at The Royal Liverpool University Hospital with Prof David Wong. Noemi then moved to Aberdeen, Scotland, where she worked as full time Consultant Ophthalmic Surgeon for 13 years.
Noemi joined Queens University in 2013 where she has been leading a programme of preclinical and clinical research focused on diabetic retinopathy and its complications. This programme of research extends from pathogenic mechanisms of disease and risk stratification to new therapies, including determining the most cost-effective therapeutic alternatives for this disease. Other research interests include retinal vein occlusion, vitreoretinal surgery and Stargardt disease.
Noemi is Chief Investigator of two large multicentre trials funded by NIHR-HTA, EMERALD (Effectiveness of Multimodal imaging for the Evaluation of Retinal oedema And New vesseLs in Diabetic retinopathy) and DIAMONDS (Diabetic Macular Oedema aNd Diode Subthreshold micropulse laser), and co-lead of the EU H2020 funded RECOGNISED (Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia).
Noemi has published over 150 articles in peer review journals [Scopus h-index (September 2023) = 45)], 13 book chapters and is editor of 3 textbooks, one on its second edition. Noemi is ad-hoc referee for numerous peer-review journals and funding bodies and has given numerous lectures as guest speaker at national and international meetings in China, Denmark, India, Indonesia, Ireland, Italy, Japan, Malaysia, Mexico, Pakistan, Singapore, South Africa, Spain, Switzerland, USA and the UK. Noemi is editorial board member for several journals including the Cochrane Eyes and Vision Group and has participated, as a member of the Evidence Review Group, in 10 Single Technology Appraisals for the UK National Institute of Health and Care Excellence (NICE) on new therapies for eye diseases.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R6636CEM: Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia (RECOGNISED)
Lois, N. (PI) & Stitt, A. (CoI)
18/12/2019 → …
Project: Research
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R1553CII: A GMP cell therapy facility to test cell based therapies
McAuley, D. (PI), Elborn, S. (CoI), Johnston, P. (CoI), Lois, N. (CoI) & McGarvey, L. (CoI)
17/08/2014 → …
Project: Research
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R1607CPH: Performance of EArly Retinal Laser (PEARL)
Congdon, N. (PI), Clarke, M. (CoI) & Lois, N. (CoI)
08/03/2016 → 31/03/2019
Project: Research
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R1437CEM: Stratifying treatment for diabetic macular oedema using induced plurlpotent stem cells
Stitt, A. (PI), Lois, N. (CoI) & Margariti, A. (CoI)
21/07/2014 → 31/08/2015
Project: Research
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R8335CEM: Targeting STAT3 for the management of diabetic retinopathy
Xu, H. (PI), Chen, M. (CoI), Lois, N. (CoI) & Lyons, T. (CoI)
27/03/2014 → 31/12/2016
Project: Research
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Face-down positioning or posturing after pars plana vitrectomy for macula-involving rhegmatogenous retinal detachments
Fung, T. H., Yim, T. W., Lois, N., Wright, D. M., Liu, S. H. & Williamson, T., 15 Mar 2024, In: Cochrane Database of Systematic Reviews. 2024, 3, 46 p., CD015514.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
Retinal vascular regeneration
Pathak, V., Bertelli, P. M., Guduric-Fuchs, J., Eyre, J., Reid, E., Lois, N., Stitt, A. W. & Medina, R. J., 09 Mar 2024, Retinal and choroidal vascular diseases of the eye. Chhablani, J. (ed.). Academic Press, p. 581-588Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids
Naderi-Meshkin, H., Setyaningsih, W. A. W., Yacoub, A., Carney, G., Cornelius, V. A., Nelson, C.-A., Kelaini, S., Donaghy, C., Dunne, P. D., Amirkhah, R., Zampetaki, A., Zeng, L., Stitt, A. W., Lois, N., Grieve, D. J. & Margariti, A., Sept 2024, In: Stem Cells. 42, 9, p. 791-808 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
Design and conduct of randomized clinical trials evaluating surgical innovations in ophthalmology: a systematic review
Azuara-Blanco, A., Carlisle, A., O'Donnell, M., Jayaram, H., Gazzard, G., Larkin, D. F. P., Wickham, L. & Lois, N., Apr 2023, In: American Journal of Ophthalmology. 248, p. 164-175 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)69 Downloads (Pure) -
Diabetic macular edema and diode subthreshold micropulse laser: A randomized double-masked noninferiority clinical trial
Lois, N., Campbell, C., Waugh, N., Azuara-Blanco, A., Maredza, M., Mistry, H., McAuley, D., Acharya, N., Aslam, T. M., Bailey, C., Chong, V., Downey, L., Eleftheriadis, H., Fatum, S., George, S., Ghanchi, F., Groppe, M., Hamilton, R., Menon, G. & Saad, A. & 7 others, , Jan 2023, In: Ophthalmology. 130, 1, p. 14-27 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)60 Downloads (Pure)
Activities
- 4 Invited talk
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Venice Ophthalmology Summer School, Venice, Italy. Activity: Giving lectures and commenting on case presentations
Lois, N. (Speaker)
10 Jul 2013 → 13 Jul 2013Activity: Talk or presentation types › Invited talk
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Combretum Retina Club, South Africa. Activity: Giving lectures as single and only guest speaker of the meeting on different Retina topics
Lois, N. (Member)
15 Aug 2012 → 19 Aug 2012Activity: Talk or presentation types › Invited talk
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Valencia Ophthalmology Society, Valencia, Spain: Giving guest speaker lecture at the meeting
Lois, N. (Speaker)
16 Apr 2011Activity: Talk or presentation types › Invited talk
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Invited lectures at the 13th International AMD and Retina Congress, Dublin, Ireland
Lois, N. (Speaker)
31 Oct 2005Activity: Talk or presentation types › Invited talk