Projects per year
Personal profile
Research Interests
Current position: Professor of Ophthalmology at the The Wellcome-Wolfson Institute for Experimental Medicine (WWIEM), Queen’s University Belfast (QUB), and Honorary Consultant Ophthalmologist and Vitreoretinal Surgeon, The Belfast Health and Social Care Trust (BHSCT)
https://pure.qub.ac.uk/en/persons/noemi-lois
ORCID: 0000-0003-2666-2937
Overview:
I am a clinical academic working in a large Department of Ophthalmology (0.5 FTE), serving a population of 1.4 million people. My clinical, surgical and research activity is focused on diabetic retinopathy and vitreoretinal surgery.
My academic portfolio includes a range of translational activities investigating mechanisms of diabetic eye disease and novel therapeutic targets. I also have expertise in technology assessment, including primary and secondary research.
Academic activities and outputs:
I have received public research funds from NIHR-HTA, MRC, EU Horizon 2020, Wellcome Trust, and several charities for a total of over £19m, since becoming an Academic in 2013.
I have published over 160 peer-reviewed papers, over > 20 book chapters, and edited three books (one is on its second edition). My work has been cited over 7000 times. My current Scopus h-index is 47.
I have been guest speaker at numerous National and International meetings taking place in Canada, China, Denmark. Germany, India, Indonesia, Ireland, Italy, Japan, Malaysia, Pakistan, Singapore, South Africa, Spain, Switzerland, USA and the UK.
I am supervisor of PhD, MSc and BSc students as well as of medical students. I am principal coordinator of a Student Selected Component Course (SSC) for first year QUB Medical Students, and I teach at this course.
I as a member of the Evidence Review Groups (ERGs) of the University of Aberdeen, the British Medical Journal, and the University of Warwick, in 10 Single Technology Appraisals (STAs) for the National Institute for Health and Care Excellence (NICE), UK, on new therapies for retinal diseases.
I was a member of the NICE committee that developed the guideline for diabetic retinopathy (https://www.nice.org.uk/guidance/ng242).
Member of the Editorial Board of the Cochrane Eyes and Vision Group.
Named lectures and awards
- King James IV Professorship, awarded by the Royal College of Surgeons of Edinburgh in 2024.
- Meyer-Schwickerath Lecture at the 36th International Congress of German Ophthalmic Surgeons (DOC) in Nuremberg, Germany, 2024.
- Mila Oh’s Memorial Lecture at the 2025 annual meeting of the Canadian Retina Society, Vancouver, Canada, 2025.
Recent publicly funded grants:
- Treatment of severe Diabetic macular oedema with Anti-vascular endothelial growth factor (anti-VEGF) monotherapy versus treatment with Anti-VEGF followed by subthreshold Micropulse lasEr when the thickness of the central retina goes below 400 microns: a pragmatic randomised equivalence trial (DAME). Funded by the HTA-NIHR (NIHR157427); Start/End dates 01/04/2024-9/30/2028; £2,060,563.00; Chief Investigator.
- Clinical- and cost-effectiveness, safety, and acceptability of COMBined phacovitrectomy, versus sequentiAl viTrectomy and cataract surgery, for the management of rhegmatogenous retinal detachment: A Randomised Equivalence Clinical Trial (COMBAT). Funded by the HTA-NIHR (NIHR161891), Start/End dates 1/11/2024-10/31/2028 £2,507,530.00 ; Chief Investigator.
- Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia (RECOGNISED): Funded by EU H2020 with € 5.9m; start date 1 January 2020. Co-Lead and Co-Coordinator of the consortium and co-applicant.
- Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative age-Related macular degeneration (TIGER): a European randomised controlled surgical trial. Funded by EURETINA-Fight for Sight with £1,799,779. Co-applicant. 1st Jan 2020 to end Dec 2024.
- EMERALD: HTA Project: 15/42/08 - Effectiveness of Multimodal imaging for the Evaluation of Retinal oedema And New vesseLs in Diabetic retinopathy (EMERALD). Funded by the NIHR with £807,895.53; 2017-2020; Chief Investigator
- DIAMONDS: Diabetic Macular Oedema aNd Diode Subthreshold micropulse laser. Funded by the National Institute for Health Research (NIHR) with £1,086,490.56; 2016-2021; Chief Investigator
- PEARL: Performance of Early Retinal Laser (PEARL) for Diabetic Retinopathy. Funded by the Medical Research Council with £127,978.00; 01/09/2016 → 31/08/2018; co-applicant.
- Ophthalmic Anatomy and Cellular Biology (Doctorate - PHD - Meiaad Dahmi A Khayat - K1452). Funded by the Royal Embassy of Saudi Arabia: £101,716.00 (2017-2020).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
R6636CEM: Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia (RECOGNISED)
Lois, N. (PI) & Stitt, A. (CoI)
18/12/2019 → …
Project: Research
-
R1607CPH: Performance of EArly Retinal Laser (PEARL)
Congdon, N. (PI), Clarke, M. (CoI) & Lois, N. (CoI)
08/03/2016 → 31/03/2019
Project: Research
-
R1553CII: A GMP cell therapy facility to test cell based therapies
McAuley, D. (PI), Elborn, S. (CoI), Johnston, P. (CoI), Lois, N. (CoI) & McGarvey, L. (CoI)
17/08/2014 → 31/03/2018
Project: Research
-
R1437CEM: Stratifying treatment for diabetic macular oedema using induced plurlpotent stem cells
Stitt, A. (PI), Lois, N. (CoI) & Margariti, A. (CoI)
21/07/2014 → 31/08/2015
Project: Research
-
R8335CEM: Targeting STAT3 for the management of diabetic retinopathy
Xu, H. (PI), Chen, M. (CoI), Lois, N. (CoI) & Lyons, T. (CoI)
27/03/2014 → 31/12/2016
Project: Research
-
Epigenetic regulation by HDAC11-driven STAT3 activation promotes pro-inflammatory cytokine production and endothelial dysfunction upon bacterial infection in diabetes
Setyaningsih, W. A. W., Naderi-Meshkin, H., Yacoub, A., Cornelius, V. A., Silva, J. D., Fitriawan, A. S., Guduric-Fuchs, J., Tashkandi, A. J. A., Kuburas, R., Zampetaki, A., Lois, N., Stitt, A. W., Valvano, M. A., Grieve, D. J., Atlasi, Y., Krasnodembskaya, A. & Margariti, A., 10 Feb 2026, (Early online date) In: Cell Communication and Signaling.Research output: Contribution to journal › Article › peer-review
Open Access -
Relationship between retinal neurodysfunction and cognitive impairment in type 2 diabetes: results of the RECOGNISED cross-sectional study
Simó, R., Hernández, C., Frontoni, S., Sbraccia, P., Schlingemann, R., Valldeperas, X., Vujosevic, S., Marques, I., Cunha-Vaz, J., Grauslund, J., Pedersen, F. N., Barahona, M.-J., Popovic, N., Zerbini, G., Ciudin, A., Perez-Hoyos, S., Exalto, L., Biessels, G. J. & Lois, N., 29 Jan 2026, (Early online date) In: Diabetologia. 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A Markov model assessing the cost-effectiveness of various anti-vascular endothelial growth factor drugs and panretinal photocoagulation for the treatment of proliferative diabetic retinopathy
Luckham, K., Tebbs, H., Claxton, L., Burgess, P., Dinah, C., Lois, N. & Mohiuddin, S., May 2025, In: Eye. 39, 7, p. 1364–1372 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)23 Downloads (Pure) -
Association between retinal microvasculature and cerebral small vessel function in type 2 diabetes: An ultrahigh field MRI study
de Leijer, J. F., Pham, S. D. T., Vissers, T. A. C. M., Exalto, L. G., Schlingemann, R. O., Siero, J. S. W., Zwanenburg, J. J. M., Simó, R., Lois, N., van Sloten, T. T., Biessels, G. J. & RECOGNISED consortium, 19 Jun 2025, (Early online date) In: Diabetes, Obesity & Metabolism.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
Cost-effectiveness of anti-vascular endothelial growth factor and macular laser treatments for people with centre-involving diabetic macular oedema and central retinal thickness of at least 400 micrometres
Luckham, K., Tebbs, H., Dadswell, C., Yosef, A., Claxton, L., Kelley, K., Taske, N., Burgess, P. I., Dinah, C., Lois, N. & Mohiuddin, S., 19 Sept 2025, (Early online date) In: Eye.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure)
Activities
- 4 Invited talk
-
Venice Ophthalmology Summer School, Venice, Italy. Activity: Giving lectures and commenting on case presentations
Lois, N. (Speaker)
10 Jul 2013 → 13 Jul 2013Activity: Talk or presentation types › Invited talk
-
Combretum Retina Club, South Africa. Activity: Giving lectures as single and only guest speaker of the meeting on different Retina topics
Lois, N. (Member)
15 Aug 2012 → 19 Aug 2012Activity: Talk or presentation types › Invited talk
-
Valencia Ophthalmology Society, Valencia, Spain: Giving guest speaker lecture at the meeting
Lois, N. (Speaker)
16 Apr 2011Activity: Talk or presentation types › Invited talk
-
Invited lectures at the 13th International AMD and Retina Congress, Dublin, Ireland
Lois, N. (Speaker)
31 Oct 2005Activity: Talk or presentation types › Invited talk