Paul McVeigh

2024

Neoblast-like stem cells of Fasciola hepatica

McCusker, P., Clarke, N. G., Gardiner, E., Armstrong, R., McCammick, E. M., McVeigh, P., Robb, E., Wells, D., Nowak-Roddy, M., Albaqami, A., Mousley, A., Coulter, J. A., Harrington, J., Marks, N. J. & Maule, A. G., 28 May 2024, In: PLoS Pathogens. 20, 5, 23 p., e1011903.

Research output: Contribution to journal › Article › peer-review

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24 Downloads (Pure)

Strongyloides questions-a research agenda for the future.

Al-Jawabreh, R., Anderson, R., Atkinson, L. E., Bickford-Smith, J., Bradbury, R. S., Breloer, M., Bryant, A. S., Buonfrate, D., Cadd, L. C., Crooks, B., Deiana, M., Grant, W., Hallem, E., Hedtke, S. M., Hunt, V., Khieu, V., Kikuchi, T., Kounosu, A., Lastik, D. & van Lieshout, L. & 14 others, Liu, Y., McSorley, H. J., McVeigh, P., Mousley, A., Murcott, B., Nevin, W. D., Nosková, E., Pomari, E., Reynolds, K., Ross, K., Streit, A., Suleiman, M., Tiberti, N. & Viney, M., 15 Jan 2024, In: Philosophical Transactions of the Royal Society B. 379, 1894, 8 p., 20230004.

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

2023

Discovery of long non-coding RNAs in the liver fluke, Fasciola hepatica

McVeigh, P., McCammick, E., Robb, E., Brophy, P., Morphew, R. M., Marks, N. J. & Maule, A. G., 28 Sept 2023, In: PLoS Neglected Tropical Diseases. 17, 9, 22 p., e0011663.

Research output: Contribution to journal › Article › peer-review

Open Access

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2 Citations (Scopus)

28 Downloads (Pure)

2022

Developmental Regulation and Functional Prediction of microRNAs in an Expanded Fasciola hepatica miRNome

Herron, C. M., O'Connor, A., Robb, E., McCammick, E., Hill, C., Marks, N. J., Robinson, M. W., Maule, A. G. & McVeigh, P., 10 Feb 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 811123.

Research output: Contribution to journal › Article › peer-review

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9 Citations (Scopus)

130 Downloads (Pure)

Developmental Regulation and Functional Prediction of microRNAs in an Expanded Fasciola hepatica miRNome

Herron, C. & McVeigh, P., 22 Mar 2022.

Research output: Contribution to conference › Poster

Pan-phylum in silico analyses of nematode endocannabinoid signalling systems highlight novel opportunities for parasite drug target discovery

Crooks, B. A., Mckenzie, D., Cadd, L. C., McCoy, C. J., McVeigh, P., Marks, N. J., Maule, A. G., Mousley, A. & Atkinson, L. E., 01 Jul 2022, In: Frontiers in Endocrinology. 13, 16 p., 892758.

Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

109 Downloads (Pure)

Transcriptomic analysis supports a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles

Robb, E., McCammick, E. M., Wells, D., McVeigh, P., Gardiner, E., Armstrong, R., McCusker, P., Mousley, A., Clarke, N., Marks, N. J. & Maule, A. G., 07 Nov 2022, In: PLoS Neglected Tropical Diseases. 16, 11, 28 p., e0010854.

Research output: Contribution to journal › Article › peer-review

Open Access

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7 Citations (Scopus)

143 Downloads (Pure)

2021

Applying 'omics' technologies to understand Fasciola spp. biology

Cwiklinski, K., Verissimo, C. D. M., McVeigh, P., Donnelly, S. & Dalton, J. P., 01 Jan 2021, Fasciolosis. 2nd ed. CABI, p. 338-378 41 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

5 Citations (Scopus)

In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles

Davey, S. D., Chalmers, I. W., Fernandez-Fuentes, N., Swain, M. T., Smith, D., Abbas Abidi, S. M., Saifullah, M. K., Raman, M., Ravikumar, G., McVeigh, P., Maule, A. G., Brophy, P. M. & Morphew, R. M., 08 Nov 2021, (Early online date) In: Molecular Omics.

Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

67 Downloads (Pure)

Phylum-spanning neuropeptide GPCR identification and prioritization: shaping drug target discovery pipelines for nematode parasite control

Atkinson, L. E., Mc Coy, C. J., Crooks, B. A., McKay, F. M., McVeigh, P., Mckenzie, D., Irvine, A., Harrington, J., Rosa, B. A., Mitreva, M., Marks, N. J., Maule, A. G. & Mousley, A., 30 Sept 2021, In: Frontiers in Endocrinology. 12, 12 p., 718363.

Research output: Contribution to journal › Article › peer-review

Open Access

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10 Citations (Scopus)

108 Downloads (Pure)

2020

Molecular characterisation and vaccine efficacy of two novel developmentally regulated surface tegument proteins of Fasciola hepatica

McCusker, P., Toet, H., Rathinasamy, V., Young, N., Beddoe, T., Anderson, G., Dempster, R., McVeigh, P., McCammick, E., Wells, D., Mousley, A., Marks, N. J., Maule, A. G. & Spithill, T. W., Oct 2020, In: Veterinary Parasitology. 286, 109244.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Post-genomic progress in helminth parasitology

McVeigh, P. (Editor), 01 Jul 2020, In: Parasitology. 147, Special Issue 8

Research output: Contribution to journal › Special issue › peer-review

Post-genomic progress in helminth parasitology

McVeigh, P., Jul 2020, In: Parasitology. 147, 8, p. 835 - 840

Research output: Contribution to journal › Editorial › peer-review

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21 Citations (Scopus)

30 Downloads (Pure)

RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development

McCusker, P., Hussain, W., McVeigh, P., McCammick, E., Clarke, N. G., Robb, E., McKay, F. M., Brophy, P. M., Timson, D. J., Mousley, A., Marks, N. J. & Maule, A. G., Dec 2020, In: International Journal for Parasitology - drugs & drug resistance. 14, p. 46-55 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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4 Citations (Scopus)

113 Downloads (Pure)

2019

Tropical diseases: Can CRISPR help in the fight against parasitic worms?

McVeigh, P. & Maule, A. G., 31 Jan 2019, In: eLife. 8, 3 p., e44382.

Research output: Contribution to journal › Article › peer-review

Open Access

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14 Citations (Scopus)

13 Downloads (Pure)

2018

Infection by the helminth parasite Fasciola hepatica requires rapid regulation of metabolic, virulence, and invasive factors to adjust to its mammalian host

Cwiklinski, K., Jewhurst, H., McVeigh, P., Barbour, T., Maule, A., Tort, J. F., O'Neill, S. M., Robinson, M., Donnelly, S. M. & Dalton, J., 10 Jan 2018, (Early online date) In: Molecular & cellular proteomics : MCP. 17, 4, p. 1-58

Research output: Contribution to journal › Article › peer-review

Open Access

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73 Citations (Scopus)

478 Downloads (Pure)

In silico analyses of protein glycosylating genes in the helminth Fasciola hepatica (liver fluke) predict protein-linked glycan simplicity and reveal temporally-dynamic expression profiles

McVeigh, P., Cwiklinski, K., Garcia-Campos, A., Mulcahy, G., O'Neill, S. M., Maule, A. & Dalton, J., 03 Aug 2018, In: Scientific Reports.

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Next-generation neuropeptide biology in liver fluke

McVeigh, P., Marks, N. & Wells, D., 30 Jan 2018.

Research output: Contribution to conference › Poster

Profiling G protein coupled receptors in Fasciola hepatica.

McVeigh, P. & Marks, N., 2018.

Research output: Contribution to conference › Paper

Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes

McVeigh, P., McCammick, E., McCusker, P., Wells, D., Hodgkinson, J. E., Paterson, S., Mousley, A., Marks, N. & Maule, A., 01 Apr 2018, In: International Journal for Parasitology - drugs & drug resistance. 8, 1, p. 87-103 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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24 Citations (Scopus)

429 Downloads (Pure)

Reasons to Be Nervous about Flukicide Discovery

McVeigh, P., McCusker, P., Robb, E., Wells, D., Gardiner, E., Mousley, A., Marks, N. J. & Maule, A. G., 01 Mar 2018, In: Trends in Parasitology. 34, 3, p. 184-196 13 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Tissue-specific transcriptome analyses provide new insights into GPCR signalling in adult Schistosoma mansoni

Hahnel, S., Wheeler, N., Lu, Z., Wangwiwatsin, A., McVeigh, P., Maule, A., Berriman, M., Day, T., Ribeiro, P. & Grevelding, C. G., 18 Jan 2018, In: PLoS Pathogens. 14, 1, 13 p., e1006718.

Research output: Contribution to journal › Review article › peer-review

Open Access

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23 Citations (Scopus)

262 Downloads (Pure)

2017

Flatworm neurobiology in the post-genomic era

McVeigh, P. & Maule, A. G., 10 Aug 2017, The Oxford handbook of invertebrate neurobiology. Byrne, J. H. (ed.). Oxford University Press, p. 219–244

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

Open Access

Profiling putative flukicide targets uncovers expansion of flatworm-expanded GPCR clusters.

McVeigh, P. & Marks, N., 2017.

Research output: Contribution to conference › Paper

Profiling putative flukicide targets uncovers expansion of flatworm-expanded GPCR clusters.

McVeigh, P. & Marks, N., 2017.

Research output: Contribution to conference › Paper

2016

Calmodulin disruption impacts growth and motility in juvenile liver fluke

McCammick, E. M., McVeigh, P., McCusker, P., Timson, D. J., Morphew, R. M., Brophy, P. M., Marks, N. J., Mousley, A. & Maule, A. G., 27 Jan 2016, In: Parasites and Vectors. 9

Research output: Contribution to journal › Article › peer-review

Open Access

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20 Citations (Scopus)

298 Downloads (Pure)

Exploring and Expanding the Fatty-Acid-Binding Protein Superfamily in Fasciola Species

Morphew, R. M., Wilkinson, T. J., Mackintosh, N., Jahndel, V., Paterson, S., McVeigh, P., Abbas Abidi, S. M., Saifullah, K. M., Raman, M., Ravikumar, G., LaCourse, J., Maule, A. & Brophy, P. M., 05 Aug 2016, In: Journal of Proteome Research. 15, 9, p. 3308-21 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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25 Citations (Scopus)

200 Downloads (Pure)

Stimulating Neoblast-Like Cell Proliferation in Juvenile Fasciola hepatica Supports Growth and Progression towards the Adult Phenotype In Vitro

McCusker, P., McVeigh, P., Rathinasamy, V., Toet, H., McCammick, E., O'Connor, A., Marks, N. J., Mousley, A., Brennan, G. P., Halton, D. W., Spithill, T. W. & Maule, A. G., 13 Sept 2016, In: PLoS Neglected Tropical Diseases. 10, 9, 26 p., e0004994.

Research output: Contribution to journal › Article › peer-review

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38 Citations (Scopus)

364 Downloads (Pure)

2014

A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress

Paul, S., Alegre, K. O., Holdsworth, S. R., Rice, M., Brown, J. A., McVeigh, P., Kelly, S. M. & Law, C. J., May 2014, In: Molecular Microbiology. 92, 4, p. 872-884 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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40 Citations (Scopus)

230 Downloads (Pure)

New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches

McCoy, C. J., Atkinson, L. E., Zamanian, M., McVeigh, P., Day, T. A., Kimber, M. J., Marks, N. J., Maule, A. G. & Mousley, A., Jun 2014, In: EuPA Open Proteomics. 3, p. 262-272 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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31 Citations (Scopus)

354 Downloads (Pure)

RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro

McVeigh, P., McCammick, E. M., McCusker, P., Morphew, R. M., Mousley, A., Abidi, A., Saifullah, K. M., Muthusamy, R., Gopalakrishnan, R., Spithill, T. W., Dalton, J. P., Brophy, P. M., Marks, N. J. & Maule, A. G., Sept 2014, In: PLoS Neglected Tropical Diseases. 8, 9, 13 p., e3185.

Research output: Contribution to journal › Article › peer-review

Open Access

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42 Citations (Scopus)

397 Downloads (Pure)

Time-dependent tegumental surface changes in juvenile Fasciola gigantica in response to triclabendazole treatment in goat

Shareef, P. A. A., Brennan, G. P., McVeigh, P., Khan, M. A. H., Morphew, R. M., Mousley, A., Marks, N. J., Saifullah, M. K., Brophy, P. M., Maule, A. G. & Abidi, S. M. A., Aug 2014, In: Acta Tropica. 136, p. 108-17 10 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

2013

Development and validation of RNA interference methods in juvenile Fasciola hepatica.

McVeigh, P. & Marks, N., 2013.

Research output: Contribution to conference › Paper

RNAi transcript and protein dynamics in juvenile Fasciola hepatica

Marks, N. & McVeigh, P., 2013.

Research output: Contribution to conference › Paper

2012

A reverse genetics approach to control target discovery in liver fluke.

McVeigh, P. & Marks, N., 2012.

Research output: Contribution to conference › Paper

A reverse genetics approach to control target discovery in liver fluke.

McVeigh, P. & Marks, N., 2012.

Research output: Contribution to conference › Paper

Considering RNAi experimental design in parasitic helminths.

Dalzell, J. J., Warnock, N. D., McVeigh, P., Marks, N. J., Mousley, A., Atkinson, L. & Maule, A. G., Apr 2012, In: Parasitology. 139, 5, p. 589-604 16 p.

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective.

McVeigh, P., Maule, A., Dalton, J. & Robinson, M., Apr 2012, In: Microbes and infection / Institut Pasteur. 14(4), 4, p. 301-310 10 p.

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptor

Zamanian, M., Agbedanu, P. N., Wheeler, N. J., McVeigh, P., Kimber, M. J. & Day, T. A., 18 Jul 2012, In: PLOS ONE. 7, 7, 10 p., e40787.

Research output: Contribution to journal › Article › peer-review

Open Access

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16 Citations (Scopus)

1 Downloads (Pure)

Parasite neuropeptide biology: Seeding rational drug target selection?

McVeigh, P., Atkinson, L., Marks, N. J., Mousley, A., Dalzell, J. J., Sluder, A., Hammerland, L. & Maule, A. G., Dec 2012, In: International Journal for Parasitology - drugs & drug resistance. 2, p. 76-91 16 p.

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Proteomics and in silico approaches to extend understanding of the glutathione transferase superfamily of the tropical liver fluke Fasciola gigantica

Morphew, R. M., Eccleston, N., Wilkinson, T. J., McGarry, J., Perally, S., Prescott, M., Ward, D., Williams, D., Paterson, S., Raman, M., Ravikumar, G., Khalid Saifullah, M., Abbas Abidi, S. M., McVeigh, P., Maule, A. G., Brophy, P. M. & LaCourse, E. J., 07 Dec 2012, In: Journal of Proteome Research. 11, 12, p. 5876-89 14 p.

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

2011

An eye on RNAi in nematode parasites

Maule, A., McVeigh, P., Dalzell, E., Atkinson, L., Mousley, A. & Marks, N., Nov 2011, In: Trends in Parasitology. 27, 11, p. 505-513 9 p.

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Development of RNAi-based gene silencing methodology in Fasciola spp. liver flukes.

McVeigh, P. & Marks, N., 2011.

Research output: Contribution to conference › Paper

Genomic insights into the origin of parasitism in the emerging plant pathogen Bursaphelenchus xylophilus

Kikuchi, T., Cotton, J. A., Dalzell, J. J., Hasegawa, K., Kanzaki, N., McVeigh, P., Takanashi, T., Tsai, I. J., Assefa, S. A., Cock, P. J. A., Otto, T. D., Hunt, M., Reid, A. J., Sanchez-Flores, A., Tsuchihara, K., Yokoi, T., Larsson, M. C., Miwa, J., Maule, A. G. & Sahashi, N. & 2 others, Jones, J. T. & Berriman, M., 01 Sept 2011, In: PLoS Pathogens. 7, 9, 17 p., e1002219.

Research output: Contribution to journal › Article › peer-review

Open Access

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350 Citations (Scopus)

9 Downloads (Pure)

108 Citations (Scopus)

Schistosome I/Lamides - A new family of bioactive helminth neuropeptides

McVeigh, P., Mair, G. R., Novozhilova, E., Day, A., Zamanian, M., Marks, N., Kimber, M. J., Day, T. & Maule, A., 08 Jul 2011, In: International Journal for Parasitology. 41, 8, p. 905-913 9 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterranea

Zamanian, M., Kimber, M. J., McVeigh, P., Carlson, S. A., Maule, A. G. & Day, T. A., 06 Dec 2011, In: BMC Genomics. 12, null, 21 p., 596.

Research output: Contribution to journal › Article › peer-review

Open Access

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72 Citations (Scopus)

13 Downloads (Pure)

2010

A PAL for Schistosoma mansoni PHM.

Atkinson, L., McVeigh, P., Kimber, M., Marks, N., Eipper, B., Mains, R., Day, T. & Maule, A., Oct 2010, In: Molecular and Biochemical Parasitology. 173(2), 2, p. 97-106 10 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Paul McVeigh

Research output

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