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PhD projects

Tandem [3,3] Sigmatropic Rearrangements for Bioactive Alkaloid Synthesis.

1982 …2019

Research output per year

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Research Output

2019

Chemoenzymatic Synthesis of (-)-Ribisins A and B from Dibenzo[b,d]furan

Boyd, D. R., Sharma, N. D., McGivern, C. J., Stevenson, P. J., Hoering, P. & Allen, C. C. R., 06 Dec 2019, In : Journal of Organic Chemistry. 84, p. 15165- 15172 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

cis‐Dihydroxylation of Tricyclic Arenes and Heteroarenes Catalyzed by Toluene Dioxygenase: A Molecular Docking Study and Experimental Validation

Boyd, D., Sharma, N. D., Brannigan, I., McGivern, C., Nockemann, P., Stevenson, P., McRoberts, C., Hoering, P. & Allen, C. C. R., 18 Mar 2019, In : Advanced Synthesis & Catalysis.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
19 Downloads (Pure)
2018

De Vries liquid crystals based on a chiral 5-phenylpyrimidine benzoate core with a tri- and tetra-carbosilane backbone

Sreenilayam, S. P., Rodriguez-Lojo, D., Agra-Kooijman, D. M., Vij, J. K., Panov, V. P., Panov, A., Fisch, M. R., Kumar, S. & Stevenson, P. J., 26 Feb 2018, In : Physical Review Materials. 2, 2, 025603.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
20 Downloads (Pure)

Enantiopurity and absolute configuration determination of arene cis-dihydrodiol metabolites and derivatives using chiral boronic acids

Boyd, D. R., Sharma, N. D., Goodrich, P. A., Malone, J. F., McConville, G., Harrison, J. S., Stevenson, P. J. & Allen, C. C. R., Jan 2018, In : Chirality. 30, 1, p. 5-18

Research output: Contribution to journalArticle

1 Citation (Scopus)

The effect of chiral doping in achiral smectic liquid crystals on the de Vries characteristics: smectic layer thickness, electro-optics and birefringence

Swaminathan, V., Panov, V. P., Panarin, Y. P., Sreenilayam, S. P., Vij, J. K., Panov, A., Rodriguez-Lojo, D., Stevenson, P. J. & Gorecka, E., 16 Mar 2018, In : Liquid Crystals. 45, 4, p. 513-521 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2017

Chiral smectic-A and smectic-C phases with de Vries characteristics

Stevenson, P., 21 Jun 2017, In : Physical Review E. 95, 6, 9 p., 062704.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
201 Downloads (Pure)

Design and investigation of de Vries liquid crystals based on 5-phenyl-pyrimidine and (R,R)-2,3-epoxyhexoxy backbone

Sreenilayam, S. P., Rodriguez-Lojo, D., Panov, V. P., Swaminathan, V., Vij, J. K., Panarin, Y. P., Gorecka, E., Panov, A. & Stevenson, P. J., 03 Oct 2017, In : Physical Review E. 96, 4, 13 p., 042701.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Enzyme-Catalysed Synthesis of Cyclohex-2-en-1-one cis-Diols from Substituted Phenols, Anilines and Derived 4-Hydroxycyclohex-2-en-1-ones

Boyd, D. R., Sharma, N. D., McIntyre, P. B. A., Stevenson, P. J., McRoberts, W. C., Gohil, A., Hoering, P. & Allen, C., 23 Nov 2017, In : Advanced Synthesis and Catalysis. 359, 22, p. 4002-4014 13 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
203 Downloads (Pure)

Observation of the de Vries behavior in SmA∗ phase of a liquid crystal using polarised Raman scattering and infrared spectroscopy

Kocot, A., Vij, J. K., Perova, T. S., Merkel, K., Swaminathan, V., Sreenilayam, S. P., Yadav, N., Panov, V. P., Stevenson, P. J., Panov, A. & Rodriguez-Lojo, D., 01 Sep 2017, In : Journal of Chemical Physics. 147, 9, 094903.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
175 Downloads (Pure)

Phase behavior and characterization of heptamethyltrisiloxane-based de Vries smectic liquid crystal by electro-optics, x rays, and dielectric spectroscopy

Sreenilayam, S. P., Agra-Kooijman, D. M., Panov, V. P., Swaminathan, V., Vij, J. K., Panarin, Y. P., Kocot, A., Panov, A., Rodriguez-Lojo, D., Stevenson, P. J., Fisch, M. R. & Kumar, S., 10 Mar 2017, In : Physical Review E. 95, 3, 11 p., 032701.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2016

Anomalous temperature dependence of layer spacing of de Vries liquid crystals: Compensation model

Merkel, K., Kocot, A., Vij, J. K., Stevenson, P. J., Panov, A. & Rodriguez, D., 13 Jun 2016, In : Applied Physics Letters. 108, 24, 243301.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
159 Downloads (Pure)
2015

Arene cis-Diol Dehydrogenase-Catalysed Regio- and Stereoselective Oxidation of Arene-, Cycloalkane- and Cycloalkene-cis-diols to Yield Catechols and Chiral α-Ketols

Boyd, D. R., Sharma, N. D., Berberian, M. V., Cleij, M., Hardacre, C., Ljubez, V., McConville, G., Stevenson, P. J., Kulakov, L. A. & Allen, C. C. R., 26 May 2015, In : Advanced Synthesis and Catalysis. 357, 8, p. 1881-1894 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1 Citation (Scopus)
202 Downloads (Pure)

Toluene Dioxygenase Catalysed synthesis and reactions of cis-diol metabolites derived from 2 and 3-methoxy phenols

Boyd, D. R., Sharma, N. D., Malone, J. F., McIntyre, P. B. A., McRoberts, C., Floyd, S., Allen, C. C. R., Gohil, A., Coles, S. J., Horton, P. N. & Stevenson, P. J., 2015, In : Journal of Organic Chemistry. 80, 7, p. 3429-3429 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Convergence of products from Povarov and von Miller reactions: approaches to helquinoline

Stevenson, P. J., He, P. & Daly, B., 07 Oct 2014, In : Tetrahedron. 70, 40, p. 7350-7357 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Reactions of enantiopure cyclic diols with sulfuryl chloride

Boyd, D. R., Sharma, N. D., Kaik, M., McIntyre, P. B. A., Malone, J. F. & Stevenson, P. J., 26 Feb 2014, In : Organic and Biomolecular Chemistry. 12, 13, p. 2128-2136 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013

Chemoenzymatic synthesis of monocyclic arene oxides and arene hydrates from substituted benzene substrates

Boyd, D. R., Sharma, N. D., Ljubez, V., McGeehin, P. K. M., Stevenson, P. J., Blain, M. & Allen, C. C. R., 26 Mar 2013, In : Organic and Biomolecular Chemistry. 11, 18, p. 3020-3029

Research output: Contribution to journalArticle

5 Citations (Scopus)

Chiral thiouronium salts: synthesis, characterisation and application in NMR enantio-discrimination of chiral oxoanions

Foreiter, M. B., Gunaratne, H. Q. N., Nockemann, P., Seddon, K. R., Stevenson, P. J. & Wassell, D. F., Feb 2013, In : New journal of chemistry. 37, 2, p. 515-533

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
362 Downloads (Pure)

Reactions of nitrogen nucleophiles with enantiopure cyclohexenyl electrophiles: a stereo- and regio- selective study

Boyd, D. R., Sharma, N. D., Belhocine, T., Malone, J. F., McGregor, S. T., Atchison, J., McIntyre, P. A. B. & Stevenson, P. J., Dec 2013, In : Journal of Physical Organic Chemistry. 26, 12, p. 997-1008 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2012

Chemoenzymatic formal synthesis of (-)- and (+)-epibatidine

Boyd, D. R., D. Sharma, N., Kaik, M., McIntyre, P. B. A., Stevenson, P. J. & Allen, C. C. R., 2012, In : Organic and Biomolecular Chemistry. 10, 14, p. 2774-2779 6 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
190 Downloads (Pure)

Chemoenzymatic synthesis of a mixed phosphine-phosphine oxide catalyst and its application to asymmetric allylation of aldehydes and hydrogenation of alkenes

Boyd, D. R., Bell, M., Dunne, K. S., Kelly, B., Stevenson, P. J., Malone, J. F. & Allen, C., 21 Feb 2012, In : Organic and Biomolecular Chemistry. 10, 7, p. 1388-1395 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Overcoming Equilibrium Issues with Carbonyl Reductase Enzymes

Calvin, S. J., Mangan, D., Miskelly, I., Moody, T. S. & Stevenson, P. J., 20 Jan 2012, In : Organic Process Research & Development. 16, 1, p. 82-86 5 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Structure, stereochemistry and synthesis of enantiopure cyclohexenone cis-diol bacterial metabolites derived from phenols

Boyd, D. R., Sharma, N. D., Malone, J. F., McIntyre, P. M. A., Stevenson, P. J., Allen, C. C. R., Kwit, M. & Gawronski, J., 2012, In : Organic and Biomolecular Chemistry. 10, 30, p. 6217-6229 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Toluene dioxygenase-catalyzed cis-dihydroxylation of benzo[b]thiophenes and benzo[b]furans: synthesis of benzo[b]thiophene 2,3-oxide

Boyd, D. R., Sharma, N. D., Brannigan, I. N., Evans, T. A., Haughey, S. A., McMurray, B. T., Malone, J. F., McIntyre, P. B. A., Stevenson, P. J. & Allen, C. C. R., Sep 2012, In : Organic & biomolecular chemistry. 10, 36, p. 7292-7304 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2011

Cycloalkenyl Halide Substitution Reactions of Enantiopure Arene cis-Tetrahydrodiols with Boron, Nitrogen and Phosphorus Nucleophiles

Boyd, D. R., Sharma, N. D., Kaik, M., Bell, M., Berberian, M. V., McIntyre, P. B. A., Kelly, B., Hardacre, C., Stevenson, P. J. & Allen, C. C. R., Sep 2011, In : Advanced Synthesis & Catalysis. 353, 13, p. 2455-2465 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
23 Citations (Scopus)
26 Citations (Scopus)

Dioxygenase-catalysed cis-dihydroxylation of meta-substituted phenols to yield cyclohexenone cis-diol and derived enantiopure cis-triol metabolites

Boyd, D., Sharma, N., Stevenson, P., Blain, M., McRoberts, C., Hamilton, J., Argudo, J. M., Mundi, H., Kulakov, L. & Allen, C., 01 Mar 2011, In : Organic and Biomolecular Chemistry. 9, 5, p. 1479-1490 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Second-order NMR spectra at high field of common organic functional groups

Stevenson, P., 07 Apr 2011, In : Organic and Biomolecular Chemistry. 9, 7, p. 2078-2084 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2010

Chemoenzymatic Synthesis of Carbasugars (+)-Pericosines A-C from Diverse Aromatic cis-Dihydrodiol Precursors

Boyd, D., Sharma, N., Acaru, C., Malone, J., O'Dowd, C., Allen, C. & Stevenson, P., 21 May 2010, In : Organic Letters. 12, 10, p. 2206-2209 4 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Chemoenzymatic synthesis of the carbasugars carba-beta-L-galactopyranose, carba-beta-L-talopyranose and carba-alpha-L-talopyranose from methyl benzoate

Boyd, D., Sharma, N., Bowers, N. I., Coen, G. B., Malone, J., O'Dowd, C., Stevenson, P. & Allen, C., 21 Mar 2010, In : Organic and Biomolecular Chemistry. 8, 6, p. 1415-1423 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Synthesis and Reactions of Enantiopure Substituted Benzene cis-Hexahydro-1,2-diols

Boyd, D., Sharma, N., Berberian, V., Dunne, K. S., Hardacre, C., Kaik, M., Kelly, B., Malone, J., McGregor, S. T. & Stevenson, P., 22 Mar 2010, In : Advanced Synthesis & Catalysis. 352, 5, p. 855-868 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2009

Palladium-mediated reductive coupling, a stereoselective approach to the 8-dehydropumiliotoxin skeleton

Feutran, S. A., McAlonan, H., Stevenson, P. & Walker, A. D., 01 Jul 2009, In : Tetrahedron Letters. 50, 26, p. 3669-3671 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2008

Facile synthesis of two diastereomeric indolizidines corresponding to the postulated structure of alkaloid 5,9E-259B from a Bufonid toad (Melanophryniscus)

Nelson, A., Garraffo, H. M., Spande, T. F., Daly, J. W. & Stevenson, P. J., 21 Jan 2008, In : Beilstein Journal of Organic Chemistry . 4, 6, 7 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
192 Downloads (Pure)
2007

Cyclic Monoarylamines

Stevenson, P., 2007, Science of Synthesis. Ramsden, C. A. (ed.). Thieme, p. 1885-1938 54 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Multi component coupling reactions of N-acetyl-2-azetine

Stevenson, P., Nieuwenhuyzen, M. & Osborne, D., 2007, In : Arkivoc. 11, 11, p. 129-144 16 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2006

Synthesis of the heterocyclic core of martinelline and martinellic acid

Hadden, M., Nieuwenhuyzen, M., Osborne, D., Stevenson, P. J., Thompson, N. & Walker, A. D., 24 Apr 2006, In : Tetrahedron. 62, 17, p. 3977-3984 8 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Synthesis of the heterocyclic core of the alkaloids Martine line and Martinellic acid

Stevenson, P., Hadden, M., Nieuwenhuyzen, M., Osborne, D. & Thompson, N., 2006, In : Tetrahedron. 42, p. 6417-6419 3 p.

Research output: Contribution to journalArticle

2005

Acylsilicon, germanium or boron Functions

Stevenson, P., 2005, Comprehensive Organic Functional Group Transformations. Katritzky, A. R., Taylor, R. J. K. & Jones, R. C. F. (eds.). Elsevier, p. 375-398 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

A revised structure for alkaloid 235C isolated from skin extracts of mantellid (Mantella) frogs of Madagascar

Andriamaharavo, N. R., Andriantsiferana, M., Stevenson, P., O'Mahony, G., Yeh, H. J. C., Kaneko, T., Garraffo, H. M., Spande, T. F. & Daly, J. W., Dec 2005, In : Journal of Natural Products. 68, 12, p. 1743-1748 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Stereoselective synthesis of (8R,8aS)-8-methylhexahydroindolizin-5-one

Armstrong, P., O'Mahony, G., Stevenson, P. & Walker, A. D., 21 Nov 2005, In : Tetrahedron Letters, ISSN. 46, 47, p. 8109-8111 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Use of cis-cyclohexanediols in synthesis.

Graham, I. P., Stevenson, P. & Boyd, D., 2005, In : Abstracts Of Papers Of The American Chemical Society. 229, p. U345-U345 1 p.

Research output: Contribution to journalArticle

2004

Acylsilicon, -germanium, or -boron functions

Stevenson, P. J., 01 Dec 2004, Comprehensive Organic Functional Group Transformations II. Elsevier Ltd, Vol. 5. p. 375-398 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rapid stereoselective access to key pumiliotoxin precursors from a common intermediate

Stevenson, P., Armstrong, P., O'Mahoney, G. & Nieuwenhuyzen, M., 28 Apr 2004, In : Journal of Organic Chemistry. 69(11), 11, p. 3968-3971 4 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Synthesis of the putative structures of homopumiliotoxins 235C and 233F

Armstrong, P., Feutren, S., McAlonan, H., O'Mahony, G. & Stevenson, P., 16 Feb 2004, In : Tetrahedron Letters. 45, 8, p. 1627-1630 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2003

Unprecedented regio and stereocontrol in Povarov reaction ofbenzylidene-(3-nitrophenyl)amine

Stevenson, P. J. & Graham, I., 01 Dec 2003, In : Arkivoc. 2003, 7, p. 139-144 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Unprecedented regio and stereocontrol in Povarov reaction of benzylidene-(3-nitrophenyl) amine

Stevenson, P. & Graham, I., 2003, In : Arkivoc. 7, p. 139-144 6 p.

Research output: Contribution to journalArticle

2002

4-Phenyloxazolidin-2-ones and isoindolin-1-ones; chiral auxiliaries for Diels-Alder reactions of N-substituted 1,3-dienes.

Stevenson, P., McAlonan, H., Murphy, J. P., Nieuwenhuyzen, M., Reynolds, K., Sarma, P. K. S. & Thompson, N., Jan 2002, In : Journal of the Chemical Society - Perkin Transactions 1. 1, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)