• Room 02.012 - Clinical Science B

    United Kingdom

1986 …2020
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Research Output 1986 2020

2020
1 Downloads (Pure)

Improving medicines management for people with dementia in primary care: a qualitative study of healthcare professionals to develop a theory-informed intervention

Barry, H. E., Bedford, L. E., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., 14 Feb 2020, In : BMC Health Services Research. 20, 13 p., 120 .

Research output: Contribution to journalArticle

Open Access
File
Dementia
Primary Health Care
Pharmacists
Delivery of Health Care
General Practitioners
2019
1 Citation (Scopus)
86 Downloads (Pure)

Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery

Pan, X., Cunningham, E. L., Passmore, A. P., McGuinness, B., McAuley, D. F., Beverland, D., O'Brien, S., Mawhinney, T., Schott, J. M., Zetterberg, H. & Green, B. D., 12 Mar 2019, In : Scientific Reports. 9, 1, 9 p., 4191.

Research output: Contribution to journalArticle

Open Access
File
Putrescine
Spermidine
Delirium
Glutamine
Orthopedics

Development of a theory-based intervention to improve medicines management for people with dementia in primary care

Barry, H. E., Bedford, L., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Feb 2019, In : International Journal of Clinical Pharmacy. 41, 1, p. 290 1 p.

Research output: Contribution to journalMeeting abstract

3 Citations (Scopus)
144 Downloads (Pure)
Open Access
File
Alzheimer disease
Alzheimer Disease
inflammation
cognition
Cognition

Electrophysiological Signatures of Cognitive Impairment in Parkinson’s Disease – A Machine Learning Approach

Sweeney, A., Devereux, B., Ong, C., McKinley, J., Foy, J., Murphy, B., McGuinness, B. & Passmore, A., 02 Sep 2019.

Research output: Contribution to conferenceAbstract

83 Citations (Scopus)
230 Downloads (Pure)

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Kunkle, B. W., Grenier-Boley, B., Sims, R., Bis, J. C., Damotte, V., Naj, A. C., Boland, A., Vronskaya, M., van der Lee, S. J., Amlie-Wolf, A., Bellenguez, C., Frizatti, A., Chouraki, V., Martin, E. R., Sleegers, K., Badarinarayan, N., Jakobsdottir, J., Hamilton-Nelson, K. L., Moreno-Grau, S., Olaso, R. & 448 others, Raybould, R., Chen, Y., Kuzma, A. B., Hiltunen, M., Morgan, T., Ahmad, S., Vardarajan, B. N., Epelbaum, J., Hoffmann, P., Boada, M., Beecham, G. W., Garnier, J. G., Harold, D., Fitzpatrick, A. L., Valladares, O., Moutet, M. L., Gerrish, A., Smith, A. V., Qu, L., Bacq, D., Denning, N., Jian, X., Zhao, Y., Del Zompo, M., Fox, N. C., Choi, S. H., Mateo, I., Hughes, J. T., Adams, H. H., Malamon, J., Sanchez-Garcia, F., Patel, Y., Brody, J. A., Dombroski, B. A., Naranjo, M. C. D., Daniilidou, M., Eiriksdottir, G., Mukherjee, S., Wallon, D., Uphill, J., Aspelund, T., Cantwell, L. B., Garzia, F., Galimberti, D., Hofer, E., Butkiewicz, M., Fin, B., Scarpini, E., Sarnowski, C., Bush, W. S., Meslage, S., Kornhuber, J., White, C. C., Song, Y., Barber, R. C., Engelborghs, S., Sordon, S., Voijnovic, D., Adams, P. M., Vandenberghe, R., Mayhaus, M., Cupples, L. A., Albert, M. S., De Deyn, P. P., Gu, W., Himali, J. J., Beekly, D., Squassina, A., Hartmann, A. M., Orellana, A., Blacker, D., Rodriguez-Rodriguez, E., Lovestone, S., Garcia, M. E., Doody, R. S., Munoz-Fernadez, C., Sussams, R., Lin, H., Fairchild, T. J., Benito, Y. A., Holmes, C., Karamujić-Čomić, H., Frosch, M. P., Thonberg, H., Maier, W., Roschupkin, G., Ghetti, B., Giedraitis, V., Kawalia, A., Li, S., Huebinger, R. M., Kilander, L., Moebus, S., Hernández, I., Kamboh, M. I., Brundin, R. M., Turton, J., Yang, Q., Katz, M. J., Concari, L., Lord, J., Beiser, A. S., Keene, C. D., Helisalmi, S., Kloszewska, I., Kukull, W. A., Koivisto, A. M., Lynch, A., Tarraga, L., Larson, E. B., Haapasalo, A., Lawlor, B., Mosley, T. H., Lipton, R. B., Solfrizzi, V., Gill, M., Longstreth, W. T., Montine, T. J., Frisardi, V., Diez-Fairen, M., Rivadeneira, F., Petersen, R. C., Deramecourt, V., Alvarez, I., Salani, F., Ciaramella, A., Boerwinkle, E., Reiman, E. M., Fievet, N., Rotter, J. I., Reisch, J. S., Hanon, O., Cupidi, C., Andre Uitterlinden, A. G., Royall, D. R., Dufouil, C., Maletta, R. G., de Rojas, I., Sano, M., Brice, A., Cecchetti, R., George-Hyslop, P. S., Ritchie, K., Tsolaki, M., Tsuang, D. W., Dubois, B., Craig, D., Wu, C. K., Soininen, H., Avramidou, D., Albin, R. L., Fratiglioni, L., Germanou, A., Apostolova, L. G., Keller, L., Koutroumani, M., Arnold, S. E., Panza, F., Gkatzima, O., Asthana, S., Hannequin, D., Whitehead, P., Atwood, C. S., Caffarra, P., Hampel, H., Quintela, I., Carracedo, Á., Lannfelt, L., Rubinsztein, D. C., Barnes, L. L., Pasquier, F., Frölich, L., Barral, S., McGuinness, B., Beach, T. G., Johnston, J. A., Becker, J. T., Passmore, P., Bigio, E. H., Schott, J. M., Bird, T. D., Warren, J. D., Boeve, B. F., Lupton, M. K., Bowen, J. D., Proitsi, P., Boxer, A., Powell, J. F., Burke, J. R., Kauwe, J. S. K., Burns, J. M., Mancuso, M., Buxbaum, J. D., Bonuccelli, U., Cairns, N. J., McQuillin, A., Cao, C., Livingston, G., Carlson, C. S., Bass, N. J., Carlsson, C. M., Hardy, J., Carney, R. M., Bras, J., Carrasquillo, M. M., Guerreiro, R., Allen, M., Chui, H. C., Fisher, E., Masullo, C., Crocco, E. A., DeCarli, C., Bisceglio, G., Dick, M., Ma, L., Duara, R., Graff-Radford, N. R., Evans, D. A., Hodges, A., Faber, K. M., Scherer, M., Fallon, K. B., Riemenschneider, M., Fardo, D. W., Heun, R., Farlow, M. R., Kölsch, H., Ferris, S., Leber, M., Foroud, T. M., Heuser, I., Galasko, D. R., Giegling, I., Gearing, M., Hüll, M., Geschwind, D. H., Gilbert, J. R., Morris, J. C., Green, R. C., Mayo, K., Growdon, J. H., Feulner, T., Hamilton, R. L., Harrell, L. E., Drichel, D., Honig, L. S., Cushion, T. D., Huentelman, M. J., Hollingworth, P., Hulette, C. M., Hyman, B. T., Marshall, R., Jarvik, G. P., Meggy, A., Abner, E., Menzies, G. E., Jin, L. W., Leonenko, G., Real, L. M., Jun, G. R., Baldwin, C. T., Grozeva, D., Karydas, A., Russo, G., Kaye, J. A., Kim, R., Jessen, F., Kowall, N. W., Vellas, B., Kramer, J. H., Vardy, E., LaFerla, F. M., Jöckel, K. H., Lah, J. J., Dichgans, M., Leverenz, J. B., Mann, D., Levey, A. I., Pickering-Brown, S., Lieberman, A. P., Klopp, N., Lunetta, K. L., Wichmann, H. E., Lyketsos, C. G., Morgan, K., Marson, D. C., Brown, K., Martiniuk, F., Medway, C., Mash, D. C., Nöthen, M. M., Masliah, E., Hooper, N. M., McCormick, W. C., Daniele, A., McCurry, S. M., Bayer, A., McDavid, A. N., Gallacher, J., McKee, A. C., van den Bussche, H., Mesulam, M., Brayne, C., Miller, B. L., Riedel-Heller, S., Miller, C. A., Miller, J. W., Al-Chalabi, A., Morris, J. C., Shaw, C. E., Myers, A. J., Wiltfang, J., O’Bryant, S., Olichney, J. M., Alvarez, V., Parisi, J. E., Singleton, A. B., Paulson, H. L., Collinge, J., Perry, W. R., Mead, S., Peskind, E., Cribbs, D. H., Rossor, M., Pierce, A., Ryan, N. S., Poon, W. W., Nacmias, B., Potter, H., Sorbi, S., Quinn, J. G., Sacchinelli, E., Raj, A., Spalletta, G., Raskind, M., Caltagirone, C., Bossù, P., Orfei, M. D., Reisberg, B., Clarke, R., Reitz, C., Smith, A. D., Ringman, J. M., Warden, D., Roberson, E. D., Wilcock, G., Rogaeva, E., Bruni, A. C., Rosen, H. J., Gallo, M., Rosenberg, R. N., Ben-Shlomo, Y., Sager, M. A., Mecocci, P., Saykin, A. J., Pastor, P., Cuccaro, M. L., Vance, J. M., Schneider, J. A., Schneider, L. S., Slifer, S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tang, M., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Saba, Y., Pilotto, A., Bullido, M. J., Peters, O., Crane, P. K., Bennett, D., Bosco, P., Coto, E., Boccardi, V., De Jager, P. L., Lleo, A., Warner, N., Lopez, O. L., Ingelsson, M., Deloukas, P., Cruchaga, C., Graff, C., Gwilliam, R., Fornage, M., Goate, A. M., Sanchez-Juan, P., Kehoe, P. G., Amin, N., Ertekin-Taner, N., Berr, C., Debette, S., Love, S., Launer, L. J., Younkin, S. G., Dartigues, J. F., Corcoran, C., Ikram, M. A., Dickson, D. W., Nicolas, G., Campion, D., Tschanz, J. A., Schmidt, H., Hakonarson, H., Clarimon, J., Munger, R., Schmidt, R., Farrer, L. A., Van Broeckhoven, C., C. O’Donovan, M., DeStefano, A. L., Jones, L., Haines, J. L., Deleuze, J. F., Owen, M. J., Gudnason, V., Mayeux, R., Escott-Price, V., Psaty, B. M., Ramirez, A., Wang, L. S., Ruiz, A., van Duijn, C. M., Holmans, P. A., Seshadri, S., Williams, J., Amouyel, P., Schellenberg, G. D., Lambert, J. C. & Pericak-Vance, M. A., 28 Feb 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

Open Access
File
Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein

Perspectives of community-dwelling people with dementia and their carers about medicines management: a qualitative study

Barry, H. E., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., 03 Apr 2019, In : International Journal of Pharmacy Practice. 27, S2, p. 15-16

Research output: Contribution to journalMeeting abstract

24 Downloads (Pure)
Open Access
File
Xanthophylls
Glomerular Filtration Rate
Kidney
Lutein
Tocopherols
140 Downloads (Pure)

Souvenaid in the management of mild cognitive impairment: An expert consensus opinion

Cummings, J., Passmore, P., McGuinness, B., Mok, V., Chen, C., Engelborghs, S., Woodward, M., Manzano, S., Garcia-Ribas, G., Cappa, S., Bertolucci, P. & Chu, L. W., 17 Aug 2019, In : Alzheimer's Research and Therapy. 11, 1, 73.

Research output: Contribution to journalReview article

Open Access
File
Expert Testimony
Consensus
Life Style
Early Diagnosis
Alzheimer Disease

Testing the feasibility of a community pharmacy-based intervention to improve medicines management for people with dementia in primary care

Barry, H. E., Bedford, L., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., 17 Sep 2019, In : European Geriatric Medicine. 10, S1, p. 62-63 2 p.

Research output: Contribution to journalMeeting abstract

The development of a comprehensive medicines management approach for persons with dementia in primary care: Full academic report

Hughes, C. M., Barry, H. E., Bedford, L. E., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M. & Buchanan, H., Mar 2019, 323 p.

Research output: Book/ReportCommissioned report

Open Access
2 Citations (Scopus)
27 Downloads (Pure)

The development of a Core Outcome Set for medicines management interventions for people with dementia in primary care

McGrattan, M., Barry, H. E., Ryan, C., Cooper, J. A., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Mar 2019, In : Age and Ageing. 48, 2, p. 260-266

Research output: Contribution to journalArticle

Open Access
File

The feasibility of mobile-EEG to profile cognitive impairment in Parkinson's disease and early-stage dementia

Sweeney, A., Devereux, B., Kearney, S., McKinley, J., Ong, C. W., Anderson, J., Murphy, B., McGuinness, B. & Passmore, A., 14 Apr 2019.

Research output: Contribution to conferenceAbstract

2018
253 Citations (Scopus)

Analysis of shared heritability in common disorders of the brain

Passmore, P., 22 Jun 2018, In : Science. 360, 6395, 12 p., eaap8757.

Research output: Contribution to journalArticle

Brain Diseases
Genome-Wide Association Study
Psychiatry
Comorbidity

A qualitative study of healthcare professionals’ perceptions of barriers and facilitators to successful medicines management for people with dementia in primary care.

Barry, H. E., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Apr 2018, In : International Journal of Pharmacy Practice. 26, S1, p. 31-32 2 p.

Research output: Contribution to journalMeeting abstract

Open Access
2 Citations (Scopus)
67 Downloads (Pure)

CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study

Cunningham, E. L., McGuinness, B., McAuley, D. F., Toombs, J., Mawhinney, T., O'Brien, S., Beverland, D., Schott, J. M., Lunn, M. P., Zetterberg, H. & Passmore, A. P., 02 Feb 2018, In : Annals of Surgery.

Research output: Contribution to journalArticle

Open Access
File
Delirium
Arthroplasty
Observational Studies
Cerebrospinal Fluid
Cohort Studies
6 Citations (Scopus)

Development of Telementoring to Enhance Assessment and Management of Pain in Advanced Dementia (TEAM Pain AD) teleECHO© Clinics for Healthcare Professionals in Primary, Secondary, Nursing Home and Hospice Settings

De Witt Jansen, B., Brazil, K., Passmore, P., Buchanan, H., Maxwell, D., McIlfatrick, S., Morgan, S., Watson, M. & Parsons, C., 01 May 2018, In : Palliative Medicine. 32, 1_suppl, p. 257 1 p.

Research output: Contribution to journalMeeting abstract

3 Citations (Scopus)
184 Downloads (Pure)
Open Access
File
Self Efficacy
Dementia
Technology
Delivery of Health Care
Pain
4 Citations (Scopus)
135 Downloads (Pure)

Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer’s Disease (AD) Pathology Than in Severe AD Pathology

Bin Nasaruddin, M., Pan, X., McGuinness, B., Passmore, A., Kehoe, P. G., Holscher, C., Graham, S. & Green, B., 26 Oct 2018, In : Metabolites. 8, 4

Research output: Contribution to journalArticle

Open Access
File
Parietal Lobe
Pathology
Alzheimer Disease
Fatty Acids
Lewy Bodies
5 Citations (Scopus)
165 Downloads (Pure)

The experiences and preparedness of family carers for best interest decision-making of a relative living with advanced dementia: A qualitative study

Carter, G., McLaughlin, D., Kernohan, G., Hudson, P., Clarke, M., Froggatt, K., Passmore, A. & Brazil, K., Jul 2018, In : Journal of Advanced Nursing. 74, 7, p. 1595-1604 10 p.

Research output: Contribution to journalArticle

Open Access
File
Caregivers
Dementia
Decision Making
Nursing Staff
Nursing Homes
3 Citations (Scopus)
157 Downloads (Pure)
Open Access
File
Dementia
Nurses
Physicians
Pain
Pain Measurement
2017
1 Citation (Scopus)
207 Downloads (Pure)

A feasibility study of a theory-based intervention to improve appropriate polypharmacy for older people in primary care

Cadogan, C. A., Ryan, C., Gormley, G., Francis, J., Passmore, P., Kerse, N. & Hughes, C. M., 20 Jul 2017, In : Pilot and Feasibility Studies. 4, 23, p. 23

Research output: Contribution to journalArticle

Open Access
File
Polypharmacy
Feasibility Studies
Primary Health Care
Referral and Consultation
General Practitioners
127 Downloads (Pure)

Beta-atrophy in Alzheimer's disease

McCague, W., Silvestri, V., Passmore, A., Silvestri, G. & Williams, M., Sep 2017, In : Eye. 31, p. 1381-1381 1 p.

Research output: Contribution to journalLetter

Open Access
File

CSF Aβ42 CONCENTRATION INDEPENDENTLY PREDICTS POSTOPERATIVE DELIRIUM IN AN ELDERLY ELECTIVE ARTHROPLASTY POPULATION

McGuinness, B., McAuley, D. F., Passmore, A. P., Cunningham, E. L., Lunn, M., Beverland, D., Mawhinney, T., Schott, J. M., Zetterberg, H., O'Brien, S. & Toombs, J., 20 Oct 2017, In : Alzheimers & dementia. 13, 7, p. P390 P1-348.

Research output: Contribution to journalMeeting abstract

15 Citations (Scopus)
439 Downloads (Pure)

Effectiveness of advance care planning with family carers in dementia nursing homes: A paired cluster randomized controlled trial

Brazil, K., Carter, G., Cardwell, C., Clarke, M., Hudson, P., Froggatt, K., McLaughlin, D., Passmore, A. & Kernohan, G., 15 Aug 2017, In : Palliative Medicine.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
203 Downloads (Pure)
Open Access
File
Northern Ireland
Glomerular Filtration Rate
Alzheimer Disease
Dementia
clopidogrel
16 Citations (Scopus)
589 Downloads (Pure)

Exploring healthcare assistants' role and experience in pain assessment and management for people with advanced dementia towards the end of life: a qualitative study

De Witt Jansen, B., Brazil, K., Passmore, P., Buchanan, H., Maxwell, D., McIlfatrick, S. J., Morgan, S. M., Watson, M. & Parsons, C., 2017, In : BMC palliative care. 16, 11 p., 6.

Research output: Contribution to journalArticle

Open Access
File
Allied Health Personnel
Pain Measurement
Pain Management
Dementia
Pain
8 Citations (Scopus)
215 Downloads (Pure)
Open Access
File
Primary Health Care
Medication Adherence
Focus Groups
Social Support
Pharmacies
18 Citations (Scopus)
131 Downloads (Pure)

Metabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer's Disease

Pan, X., Elliott, C. T., McGuinness, B., Passmore, P., Kehoe, P. G., Hölscher, C., McClean, P. L., Graham, S. F. & Green, B. D., 17 Jun 2017, In : Metabolites. 7, 2, 12 p., 28.

Research output: Contribution to journalArticle

Open Access
File
Metabolomics
Bile Acids and Salts
Alzheimer Disease
Brain
Taurocholic Acid
5 Citations (Scopus)

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array

Barber, I. S., Braae, A., Clement, N., Patel, T., Guetta-Baranes, T., Brookes, K., Medway, C., Chappell, S., Guerreiro, R., Bras, J., Hernandez, D., Singleton, A. B., Hardy, J., Mann, D. M., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R. & 16 others, Kölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Pickering-Brown, S., Snowden, J., Richardson, A., Jones, M., Neary, D., Harris, J., Lowe, J., Smith, A. D., Wilcock, G., Warden, D., Holmes, C. & Morgan, K., 01 Jan 2017, In : Neurobiology of Aging. 49, p. 215.e1-215.e8

Research output: Contribution to journalArticle

Parkinson Disease
Alzheimer Disease
Mutation
Genes
7 Citations (Scopus)
3308 Downloads (Pure)

Nurses' experiences of pain management for people with advanced dementia approaching the end of life: a qualitative study

De Witt Jansen, B., Brazil, K., Passmore, P., Buchanan, H., Maxwell, D., Mcilfatrick, S. J., Morgan, S. M., Watson, M. & Parsons, C., 05 Apr 2017, In : Journal of Clinical Nursing. 26, 9-10, p. 1234-1244 11 p.

Research output: Contribution to journalArticle

Open Access
File
Pain Management
Dementia
Nurses
Nursing Homes
Hospice and Palliative Care Nursing
5 Citations (Scopus)
106 Downloads (Pure)
Open Access
File
Delirium
Apolipoproteins E
Arthroplasty
Observational Studies
Cohort Studies

Pharmacists’ perceptions of the barriers and facilitators to successful medicines management for people with dementia in primary care

McGrattan, M., Barry, H., Ryan, C., Cooper, J., Passmore, A. P., Robinson, A. L., Molloy, G., Darcy, C., Buchanan, H. & Hughes, C., Apr 2017, In : International Journal of Pharmacy Practice. 25, S1, p. 15-16

Research output: Contribution to journalMeeting abstract

1 Citation (Scopus)

Pisa syndrome due to donepezil: pharmacokinetic interactions to blame?

Pollock, D., Cunningham, E., McGuinness, B. & Passmore, A. P., 24 Jan 2017, In : Age and Ageing. 46, 3, p. 529-530 2 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Cholinesterase Inhibitors
Caregivers
donepezil
208 Citations (Scopus)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

ARUK Consortium, 17 Jul 2017, In : Nature Genetics. 49, 9, p. 1373-1384

Research output: Contribution to journalArticle

Innate Immunity
Alzheimer Disease
Odds Ratio
Microglia
Genotype
12 Citations (Scopus)
138 Downloads (Pure)
Open Access
File
Carotenoids
Vitamin E
Case-Control Studies
Alzheimer Disease
Tocopherols

Supporting family carers in best interest decision-making in dementia care at the end of life: Findings from a cluster randomised control trial

Brazil, K., Carter, G., Cardwell, C., Clarke, M., Hudson, P., Froggatt, K., McLaughlin, D., Passmore, A. & Kernohan, W. G., 01 Sep 2017, In : BMJ Supportive and Palliative Care. 7, 3, 1 p., A347.

Research output: Contribution to journalMeeting abstract

3 Citations (Scopus)
439 Downloads (Pure)

“There’s a Catch-22”. The complexities of pain management for people with advanced dementia nearing the end of life: a qualitative exploration of physicians’ perspectives

De Witt Jansen, B., Brazil, K., Passmore, P., Buchanan, H., Maxwell, D., McIlfatrick, S. J., Morgan, S. M., Watson, M. & Parsons, C., 01 Sep 2017, In : Palliative Medicine. 31 , 8, p. 734-742 9 p.

Research output: Contribution to journalArticle

Open Access
File
Pain Management
Dementia
Physicians
Palliative Care
Hospice Care
2016
40 Citations (Scopus)
258 Downloads (Pure)

Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome

Pan, X., Bin Nasaruddin, M., Elliott, C. T., McGuinness, B., Passmore, A. P., Kehoe, P. G., Holscher, C., McClean, P. L., Graham, S. F. & Green, B. D., Feb 2016, In : Neurobiology of Aging. 38, p. 151-163 13 p.

Research output: Contribution to journalArticle

Open Access
File
Metabolome
Alzheimer Disease
Pathology
Brain
Branched Chain Amino Acids
3 Citations (Scopus)
120 Downloads (Pure)

A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol

Greenan, C., Murphy, L., Yu, L-M., Kehoe, P. G., Coulthard, E., Bath, P., Stewart, R., Jones, R., Corbett, A., Thomas, A., Connelly, P., Arrojo, F., Canning, R., Wallach, S., Henderson, C., McGuinness, B., O'Sullivan, M., Holmes, C., Knapp, M., Ballard, C. & 2 others, Passmore, P. & AFFECT Investigators, 18 Jul 2016, In : Trials. 17, 324, 12 p.

Research output: Contribution to journalArticle

Open Access
File
Amlodipine
Vascular Dementia
Calcium Channels
Randomized Controlled Trials
Therapeutics
169 Downloads (Pure)

"A Tool Doesn't Add Anything" Physicians' Perceptions and Use of Pain Assessment Tools with People with Advanced Dementia Approaching the End of Life

De Witt Jansen, B., Brazil, K., Passmore, A., Buchanan, H., Maxwell, D., McIlfatrick, S., Morgan, S., Watson, M. & Parsons, C., Jun 2016, In : Palliative Medicine. 30, 6, p. NP37 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
File
9 Citations (Scopus)
237 Downloads (Pure)

A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort

Skrobot, O. A., McKnight, A. J., Passmore, P. A., Seripa, D., Mecocci, P., Panza, F., Kalaria, R., Wilcock, G., Munafò, M., Erkinjuntti, T., Karhunen, P., Pessi, T., Martiskainen, M., Love, S., Kehoe, P. G. & Genetic and Environmental Risk for Alzheimer’s disease Consortium (GERAD1), 15 Jun 2016, In : Journal of Alzheimer's disease : JAD.

Research output: Contribution to journalArticle

Open Access
File
Validation Studies
Blood Vessels
Meta-Analysis
Vascular Dementia
Alleles

Considerations on the feasibility and acceptability of an advance care planning intervention for dementia residents in UK care homes

Brazil, K., Carter, G., McLaughlin, D., Kernohan, G., Hudson, P., Clarke, M., Passmore, A. & Froggart, K., 06 Oct 2016, p. S108. 1 p.

Research output: Contribution to conferencePoster

8 Citations (Scopus)
193 Downloads (Pure)

Development of an intervention to improve appropriate polypharmacy in older people in primary care using a theory-based method

Cadogan, C. A., Ryan, C., Francis, J. J., Gormley, G., Passmore, P., Kerse, N. & Hughes, C. M., 16 Nov 2016, In : BMC Health Services Research. 16, 1, 10 p., 661.

Research output: Contribution to journalArticle

Open Access
File
Polypharmacy
Primary Health Care
General Practitioners
Pharmacists
Feasibility Studies
69 Downloads (Pure)

Development of a primary care-based intervention to improve appropriate polypharmacy in older people using a systematic and theory-based method.

Cadogan, C. A., Ryan, C., Francis, J. J., Gormley, G., Passmore, A., Kerse, N. & Hughes, C., 16 Nov 2016, In : International Journal of Pharmacy Practice. 24, p. 16-17

Research output: Contribution to journalMeeting abstract

Open Access
File
Polypharmacy
Primary Health Care
General Practitioners
Testing
Taxonomies

Evaluation of an advance care planning intervention in dementia care homes: aspects of feasibility and acceptability

Brazil, K., Carter, G., McLaughlin, D., Kernohan, G., Hudson, P., Clarke, M., Passmore, A. & Froggart, K., Nov 2016.

Research output: Contribution to conferencePoster

12 Citations (Scopus)
Independent Living
dementia
cross-sectional study
Dementia
pain
26 Citations (Scopus)
129 Downloads (Pure)

"I Don't Need a Piece of Paper with Scores to Tell Me that Somebody's in Pain and I Need to Do Something about it". Nurses' and Healthcare Assistants' Perspectives on and Use of Pain Assessment Tools with People Dying with Advanced Dementia

De Witt Jansen, B., Brazil, K., Passmore, A., Buchanan, H., Maxwell, D., McIlfatrick, S., Morgan, S., Watson, M. & Parsons, C., Jun 2016, In : Palliative Medicine. 30, 6, p. NP45-NP46 2 p.

Research output: Contribution to journalMeeting abstract

Open Access
File
9 Citations (Scopus)
132 Downloads (Pure)

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer’s Disease

Sassi, C., Ridge, P. G., Nalls, M. A., Gibbs, R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Lord, J., Turton, J., Morgan, K., Powell, J. F., Kauwe, J. S. K., Cruchaga, C., Bras, J., Goate, A. M., Singleton, A. B. & 18 others, Guerreiro, R., Hardy, J., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R., Kölsch, H., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Mann, D. M., Lowe, J., David Smith, A., Wilcock, G., Warden, D. & Holmes, C., 01 Jun 2016, In : PLoS ONE. 11, 6, e0150079.

Research output: Contribution to journalArticle

Open Access
File
Serum Amyloid A Protein
Amyloid beta-Protein Precursor
Staphylococcal Protein A
amyloid
Alzheimer disease