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Research Output 1986 2020

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2020
4 Downloads (Pure)

Improving medicines management for people with dementia in primary care: a qualitative study of healthcare professionals to develop a theory-informed intervention

Barry, H. E., Bedford, L. E., McGrattan, M., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., 14 Feb 2020, In : BMC Health Services Research. 20, 13 p., 120 .

Research output: Contribution to journalArticle

Open Access
File
Dementia
Primary Health Care
Pharmacists
Delivery of Health Care
General Practitioners
2019
1 Citation (Scopus)
86 Downloads (Pure)

Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery

Pan, X., Cunningham, E. L., Passmore, A. P., McGuinness, B., McAuley, D. F., Beverland, D., O'Brien, S., Mawhinney, T., Schott, J. M., Zetterberg, H. & Green, B. D., 12 Mar 2019, In : Scientific Reports. 9, 1, 9 p., 4191.

Research output: Contribution to journalArticle

Open Access
File
Putrescine
Spermidine
Delirium
Glutamine
Orthopedics
90 Citations (Scopus)
236 Downloads (Pure)

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Kunkle, B. W., Grenier-Boley, B., Sims, R., Bis, J. C., Damotte, V., Naj, A. C., Boland, A., Vronskaya, M., van der Lee, S. J., Amlie-Wolf, A., Bellenguez, C., Frizatti, A., Chouraki, V., Martin, E. R., Sleegers, K., Badarinarayan, N., Jakobsdottir, J., Hamilton-Nelson, K. L., Moreno-Grau, S., Olaso, R. & 448 others, Raybould, R., Chen, Y., Kuzma, A. B., Hiltunen, M., Morgan, T., Ahmad, S., Vardarajan, B. N., Epelbaum, J., Hoffmann, P., Boada, M., Beecham, G. W., Garnier, J. G., Harold, D., Fitzpatrick, A. L., Valladares, O., Moutet, M. L., Gerrish, A., Smith, A. V., Qu, L., Bacq, D., Denning, N., Jian, X., Zhao, Y., Del Zompo, M., Fox, N. C., Choi, S. H., Mateo, I., Hughes, J. T., Adams, H. H., Malamon, J., Sanchez-Garcia, F., Patel, Y., Brody, J. A., Dombroski, B. A., Naranjo, M. C. D., Daniilidou, M., Eiriksdottir, G., Mukherjee, S., Wallon, D., Uphill, J., Aspelund, T., Cantwell, L. B., Garzia, F., Galimberti, D., Hofer, E., Butkiewicz, M., Fin, B., Scarpini, E., Sarnowski, C., Bush, W. S., Meslage, S., Kornhuber, J., White, C. C., Song, Y., Barber, R. C., Engelborghs, S., Sordon, S., Voijnovic, D., Adams, P. M., Vandenberghe, R., Mayhaus, M., Cupples, L. A., Albert, M. S., De Deyn, P. P., Gu, W., Himali, J. J., Beekly, D., Squassina, A., Hartmann, A. M., Orellana, A., Blacker, D., Rodriguez-Rodriguez, E., Lovestone, S., Garcia, M. E., Doody, R. S., Munoz-Fernadez, C., Sussams, R., Lin, H., Fairchild, T. J., Benito, Y. A., Holmes, C., Karamujić-Čomić, H., Frosch, M. P., Thonberg, H., Maier, W., Roschupkin, G., Ghetti, B., Giedraitis, V., Kawalia, A., Li, S., Huebinger, R. M., Kilander, L., Moebus, S., Hernández, I., Kamboh, M. I., Brundin, R. M., Turton, J., Yang, Q., Katz, M. J., Concari, L., Lord, J., Beiser, A. S., Keene, C. D., Helisalmi, S., Kloszewska, I., Kukull, W. A., Koivisto, A. M., Lynch, A., Tarraga, L., Larson, E. B., Haapasalo, A., Lawlor, B., Mosley, T. H., Lipton, R. B., Solfrizzi, V., Gill, M., Longstreth, W. T., Montine, T. J., Frisardi, V., Diez-Fairen, M., Rivadeneira, F., Petersen, R. C., Deramecourt, V., Alvarez, I., Salani, F., Ciaramella, A., Boerwinkle, E., Reiman, E. M., Fievet, N., Rotter, J. I., Reisch, J. S., Hanon, O., Cupidi, C., Andre Uitterlinden, A. G., Royall, D. R., Dufouil, C., Maletta, R. G., de Rojas, I., Sano, M., Brice, A., Cecchetti, R., George-Hyslop, P. S., Ritchie, K., Tsolaki, M., Tsuang, D. W., Dubois, B., Craig, D., Wu, C. K., Soininen, H., Avramidou, D., Albin, R. L., Fratiglioni, L., Germanou, A., Apostolova, L. G., Keller, L., Koutroumani, M., Arnold, S. E., Panza, F., Gkatzima, O., Asthana, S., Hannequin, D., Whitehead, P., Atwood, C. S., Caffarra, P., Hampel, H., Quintela, I., Carracedo, Á., Lannfelt, L., Rubinsztein, D. C., Barnes, L. L., Pasquier, F., Frölich, L., Barral, S., McGuinness, B., Beach, T. G., Johnston, J. A., Becker, J. T., Passmore, P., Bigio, E. H., Schott, J. M., Bird, T. D., Warren, J. D., Boeve, B. F., Lupton, M. K., Bowen, J. D., Proitsi, P., Boxer, A., Powell, J. F., Burke, J. R., Kauwe, J. S. K., Burns, J. M., Mancuso, M., Buxbaum, J. D., Bonuccelli, U., Cairns, N. J., McQuillin, A., Cao, C., Livingston, G., Carlson, C. S., Bass, N. J., Carlsson, C. M., Hardy, J., Carney, R. M., Bras, J., Carrasquillo, M. M., Guerreiro, R., Allen, M., Chui, H. C., Fisher, E., Masullo, C., Crocco, E. A., DeCarli, C., Bisceglio, G., Dick, M., Ma, L., Duara, R., Graff-Radford, N. R., Evans, D. A., Hodges, A., Faber, K. M., Scherer, M., Fallon, K. B., Riemenschneider, M., Fardo, D. W., Heun, R., Farlow, M. R., Kölsch, H., Ferris, S., Leber, M., Foroud, T. M., Heuser, I., Galasko, D. R., Giegling, I., Gearing, M., Hüll, M., Geschwind, D. H., Gilbert, J. R., Morris, J. C., Green, R. C., Mayo, K., Growdon, J. H., Feulner, T., Hamilton, R. L., Harrell, L. E., Drichel, D., Honig, L. S., Cushion, T. D., Huentelman, M. J., Hollingworth, P., Hulette, C. M., Hyman, B. T., Marshall, R., Jarvik, G. P., Meggy, A., Abner, E., Menzies, G. E., Jin, L. W., Leonenko, G., Real, L. M., Jun, G. R., Baldwin, C. T., Grozeva, D., Karydas, A., Russo, G., Kaye, J. A., Kim, R., Jessen, F., Kowall, N. W., Vellas, B., Kramer, J. H., Vardy, E., LaFerla, F. M., Jöckel, K. H., Lah, J. J., Dichgans, M., Leverenz, J. B., Mann, D., Levey, A. I., Pickering-Brown, S., Lieberman, A. P., Klopp, N., Lunetta, K. L., Wichmann, H. E., Lyketsos, C. G., Morgan, K., Marson, D. C., Brown, K., Martiniuk, F., Medway, C., Mash, D. C., Nöthen, M. M., Masliah, E., Hooper, N. M., McCormick, W. C., Daniele, A., McCurry, S. M., Bayer, A., McDavid, A. N., Gallacher, J., McKee, A. C., van den Bussche, H., Mesulam, M., Brayne, C., Miller, B. L., Riedel-Heller, S., Miller, C. A., Miller, J. W., Al-Chalabi, A., Morris, J. C., Shaw, C. E., Myers, A. J., Wiltfang, J., O’Bryant, S., Olichney, J. M., Alvarez, V., Parisi, J. E., Singleton, A. B., Paulson, H. L., Collinge, J., Perry, W. R., Mead, S., Peskind, E., Cribbs, D. H., Rossor, M., Pierce, A., Ryan, N. S., Poon, W. W., Nacmias, B., Potter, H., Sorbi, S., Quinn, J. G., Sacchinelli, E., Raj, A., Spalletta, G., Raskind, M., Caltagirone, C., Bossù, P., Orfei, M. D., Reisberg, B., Clarke, R., Reitz, C., Smith, A. D., Ringman, J. M., Warden, D., Roberson, E. D., Wilcock, G., Rogaeva, E., Bruni, A. C., Rosen, H. J., Gallo, M., Rosenberg, R. N., Ben-Shlomo, Y., Sager, M. A., Mecocci, P., Saykin, A. J., Pastor, P., Cuccaro, M. L., Vance, J. M., Schneider, J. A., Schneider, L. S., Slifer, S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tang, M., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Saba, Y., Pilotto, A., Bullido, M. J., Peters, O., Crane, P. K., Bennett, D., Bosco, P., Coto, E., Boccardi, V., De Jager, P. L., Lleo, A., Warner, N., Lopez, O. L., Ingelsson, M., Deloukas, P., Cruchaga, C., Graff, C., Gwilliam, R., Fornage, M., Goate, A. M., Sanchez-Juan, P., Kehoe, P. G., Amin, N., Ertekin-Taner, N., Berr, C., Debette, S., Love, S., Launer, L. J., Younkin, S. G., Dartigues, J. F., Corcoran, C., Ikram, M. A., Dickson, D. W., Nicolas, G., Campion, D., Tschanz, J. A., Schmidt, H., Hakonarson, H., Clarimon, J., Munger, R., Schmidt, R., Farrer, L. A., Van Broeckhoven, C., C. O’Donovan, M., DeStefano, A. L., Jones, L., Haines, J. L., Deleuze, J. F., Owen, M. J., Gudnason, V., Mayeux, R., Escott-Price, V., Psaty, B. M., Ramirez, A., Wang, L. S., Ruiz, A., van Duijn, C. M., Holmans, P. A., Seshadri, S., Williams, J., Amouyel, P., Schellenberg, G. D., Lambert, J. C. & Pericak-Vance, M. A., 28 Feb 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

Open Access
File
Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein
28 Downloads (Pure)
Open Access
File
Xanthophylls
Glomerular Filtration Rate
Kidney
Lutein
Tocopherols
2 Citations (Scopus)
29 Downloads (Pure)

The development of a Core Outcome Set for medicines management interventions for people with dementia in primary care

McGrattan, M., Barry, H. E., Ryan, C., Cooper, J. A., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., Mar 2019, In : Age and Ageing. 48, 2, p. 260-266

Research output: Contribution to journalArticle

Open Access
File
2018
259 Citations (Scopus)

Analysis of shared heritability in common disorders of the brain

Passmore, P., 22 Jun 2018, In : Science. 360, 6395, 12 p., eaap8757.

Research output: Contribution to journalArticle

Brain Diseases
Genome-Wide Association Study
Psychiatry
Comorbidity
2 Citations (Scopus)
69 Downloads (Pure)

CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study

Cunningham, E. L., McGuinness, B., McAuley, D. F., Toombs, J., Mawhinney, T., O'Brien, S., Beverland, D., Schott, J. M., Lunn, M. P., Zetterberg, H. & Passmore, A. P., 02 Feb 2018, In : Annals of Surgery.

Research output: Contribution to journalArticle

Open Access
File
Delirium
Arthroplasty
Observational Studies
Cerebrospinal Fluid
Cohort Studies
5 Citations (Scopus)
188 Downloads (Pure)
Open Access
File
Self Efficacy
Dementia
Technology
Delivery of Health Care
Pain
4 Citations (Scopus)
139 Downloads (Pure)

Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer’s Disease (AD) Pathology Than in Severe AD Pathology

Bin Nasaruddin, M., Pan, X., McGuinness, B., Passmore, A., Kehoe, P. G., Holscher, C., Graham, S. & Green, B., 26 Oct 2018, In : Metabolites. 8, 4

Research output: Contribution to journalArticle

Open Access
File
Parietal Lobe
Pathology
Alzheimer Disease
Fatty Acids
Lewy Bodies
6 Citations (Scopus)
165 Downloads (Pure)

The experiences and preparedness of family carers for best interest decision-making of a relative living with advanced dementia: A qualitative study

Carter, G., McLaughlin, D., Kernohan, G., Hudson, P., Clarke, M., Froggatt, K., Passmore, A. & Brazil, K., Jul 2018, In : Journal of Advanced Nursing. 74, 7, p. 1595-1604 10 p.

Research output: Contribution to journalArticle

Open Access
File
Caregivers
Dementia
Decision Making
Nursing Staff
Nursing Homes
3 Citations (Scopus)
165 Downloads (Pure)
Open Access
File
Dementia
Nurses
Physicians
Pain
Pain Measurement
2017
1 Citation (Scopus)
211 Downloads (Pure)

A feasibility study of a theory-based intervention to improve appropriate polypharmacy for older people in primary care

Cadogan, C. A., Ryan, C., Gormley, G., Francis, J., Passmore, P., Kerse, N. & Hughes, C. M., 20 Jul 2017, In : Pilot and Feasibility Studies. 4, 23, p. 23

Research output: Contribution to journalArticle

Open Access
File
Polypharmacy
Feasibility Studies
Primary Health Care
Referral and Consultation
General Practitioners
15 Citations (Scopus)
450 Downloads (Pure)

Effectiveness of advance care planning with family carers in dementia nursing homes: A paired cluster randomized controlled trial

Brazil, K., Carter, G., Cardwell, C., Clarke, M., Hudson, P., Froggatt, K., McLaughlin, D., Passmore, A. & Kernohan, G., 15 Aug 2017, In : Palliative Medicine.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
207 Downloads (Pure)
Open Access
File
Northern Ireland
Glomerular Filtration Rate
Alzheimer Disease
Dementia
clopidogrel
16 Citations (Scopus)
595 Downloads (Pure)

Exploring healthcare assistants' role and experience in pain assessment and management for people with advanced dementia towards the end of life: a qualitative study

De Witt Jansen, B., Brazil, K., Passmore, P., Buchanan, H., Maxwell, D., McIlfatrick, S. J., Morgan, S. M., Watson, M. & Parsons, C., 2017, In : BMC palliative care. 16, 11 p., 6.

Research output: Contribution to journalArticle

Open Access
File
Allied Health Personnel
Pain Measurement
Pain Management
Dementia
Pain
8 Citations (Scopus)
222 Downloads (Pure)
Open Access
File
Primary Health Care
Medication Adherence
Focus Groups
Social Support
Pharmacies
18 Citations (Scopus)
135 Downloads (Pure)

Metabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer's Disease

Pan, X., Elliott, C. T., McGuinness, B., Passmore, P., Kehoe, P. G., Hölscher, C., McClean, P. L., Graham, S. F. & Green, B. D., 17 Jun 2017, In : Metabolites. 7, 2, 12 p., 28.

Research output: Contribution to journalArticle

Open Access
File
Metabolomics
Bile Acids and Salts
Alzheimer Disease
Brain
Taurocholic Acid
6 Citations (Scopus)

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array

Barber, I. S., Braae, A., Clement, N., Patel, T., Guetta-Baranes, T., Brookes, K., Medway, C., Chappell, S., Guerreiro, R., Bras, J., Hernandez, D., Singleton, A. B., Hardy, J., Mann, D. M., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R. & 16 others, Kölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Pickering-Brown, S., Snowden, J., Richardson, A., Jones, M., Neary, D., Harris, J., Lowe, J., Smith, A. D., Wilcock, G., Warden, D., Holmes, C. & Morgan, K., 01 Jan 2017, In : Neurobiology of Aging. 49, p. 215.e1-215.e8

Research output: Contribution to journalArticle

Parkinson Disease
Alzheimer Disease
Mutation
Genes
7 Citations (Scopus)
3327 Downloads (Pure)

Nurses' experiences of pain management for people with advanced dementia approaching the end of life: a qualitative study

De Witt Jansen, B., Brazil, K., Passmore, P., Buchanan, H., Maxwell, D., Mcilfatrick, S. J., Morgan, S. M., Watson, M. & Parsons, C., 05 Apr 2017, In : Journal of Clinical Nursing. 26, 9-10, p. 1234-1244 11 p.

Research output: Contribution to journalArticle

Open Access
File
Pain Management
Dementia
Nurses
Nursing Homes
Hospice and Palliative Care Nursing
5 Citations (Scopus)
110 Downloads (Pure)
Open Access
File
Delirium
Apolipoproteins E
Arthroplasty
Observational Studies
Cohort Studies
2 Citations (Scopus)

Pisa syndrome due to donepezil: pharmacokinetic interactions to blame?

Pollock, D., Cunningham, E., McGuinness, B. & Passmore, A. P., 24 Jan 2017, In : Age and Ageing. 46, 3, p. 529-530 2 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Cholinesterase Inhibitors
Caregivers
donepezil
209 Citations (Scopus)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

ARUK Consortium, 17 Jul 2017, In : Nature Genetics. 49, 9, p. 1373-1384

Research output: Contribution to journalArticle

Innate Immunity
Alzheimer Disease
Odds Ratio
Microglia
Genotype
12 Citations (Scopus)
142 Downloads (Pure)
Open Access
File
Carotenoids
Vitamin E
Case-Control Studies
Alzheimer Disease
Tocopherols
3 Citations (Scopus)
443 Downloads (Pure)

“There’s a Catch-22”. The complexities of pain management for people with advanced dementia nearing the end of life: a qualitative exploration of physicians’ perspectives

De Witt Jansen, B., Brazil, K., Passmore, P., Buchanan, H., Maxwell, D., McIlfatrick, S. J., Morgan, S. M., Watson, M. & Parsons, C., 01 Sep 2017, In : Palliative Medicine. 31 , 8, p. 734-742 9 p.

Research output: Contribution to journalArticle

Open Access
File
Pain Management
Dementia
Physicians
Palliative Care
Hospice Care
2016
42 Citations (Scopus)
263 Downloads (Pure)

Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome

Pan, X., Bin Nasaruddin, M., Elliott, C. T., McGuinness, B., Passmore, A. P., Kehoe, P. G., Holscher, C., McClean, P. L., Graham, S. F. & Green, B. D., Feb 2016, In : Neurobiology of Aging. 38, p. 151-163 13 p.

Research output: Contribution to journalArticle

Open Access
File
Metabolome
Alzheimer Disease
Pathology
Brain
Branched Chain Amino Acids
3 Citations (Scopus)
126 Downloads (Pure)

A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol

Greenan, C., Murphy, L., Yu, L-M., Kehoe, P. G., Coulthard, E., Bath, P., Stewart, R., Jones, R., Corbett, A., Thomas, A., Connelly, P., Arrojo, F., Canning, R., Wallach, S., Henderson, C., McGuinness, B., O'Sullivan, M., Holmes, C., Knapp, M., Ballard, C. & 2 others, Passmore, P. & AFFECT Investigators, 18 Jul 2016, In : Trials. 17, 324, 12 p.

Research output: Contribution to journalArticle

Open Access
File
Amlodipine
Vascular Dementia
Calcium Channels
Randomized Controlled Trials
Therapeutics
9 Citations (Scopus)
243 Downloads (Pure)

A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort

Skrobot, O. A., McKnight, A. J., Passmore, P. A., Seripa, D., Mecocci, P., Panza, F., Kalaria, R., Wilcock, G., Munafò, M., Erkinjuntti, T., Karhunen, P., Pessi, T., Martiskainen, M., Love, S., Kehoe, P. G. & Genetic and Environmental Risk for Alzheimer’s disease Consortium (GERAD1), 15 Jun 2016, In : Journal of Alzheimer's disease : JAD.

Research output: Contribution to journalArticle

Open Access
File
Validation Studies
Blood Vessels
Meta-Analysis
Vascular Dementia
Alleles
8 Citations (Scopus)
197 Downloads (Pure)

Development of an intervention to improve appropriate polypharmacy in older people in primary care using a theory-based method

Cadogan, C. A., Ryan, C., Francis, J. J., Gormley, G., Passmore, P., Kerse, N. & Hughes, C. M., 16 Nov 2016, In : BMC Health Services Research. 16, 1, 10 p., 661.

Research output: Contribution to journalArticle

Open Access
File
Polypharmacy
Primary Health Care
General Practitioners
Pharmacists
Feasibility Studies
13 Citations (Scopus)
Independent Living
dementia
cross-sectional study
Dementia
pain
9 Citations (Scopus)
135 Downloads (Pure)

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer’s Disease

Sassi, C., Ridge, P. G., Nalls, M. A., Gibbs, R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Lord, J., Turton, J., Morgan, K., Powell, J. F., Kauwe, J. S. K., Cruchaga, C., Bras, J., Goate, A. M., Singleton, A. B. & 18 others, Guerreiro, R., Hardy, J., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R., Kölsch, H., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Mann, D. M., Lowe, J., David Smith, A., Wilcock, G., Warden, D. & Holmes, C., 01 Jun 2016, In : PLoS ONE. 11, 6, e0150079.

Research output: Contribution to journalArticle

Open Access
File
Serum Amyloid A Protein
Amyloid beta-Protein Precursor
Staphylococcal Protein A
amyloid
Alzheimer disease
5 Citations (Scopus)
135 Downloads (Pure)
Open Access
File
Amyloid Precursor Protein Secretases
Longitudinal Studies
Dementia
Blood Platelets
Alzheimer Disease
11 Citations (Scopus)
817 Downloads (Pure)

Potentially inappropriate prescribing among people with dementia in primary care: a retrospective cross-sectional study using the Enhanced Prescribing Database

Barry, H. E., Cooper, J. A., Ryan, C., Passmore, A. P., Robinson, A. L., Molloy, G. J., Darcy, C. M., Buchanan, H. & Hughes, C. M., 2016, In : Journal of Alzheimer's disease : JAD. 52, 4, p. 1503-1513

Research output: Contribution to journalArticle

Open Access
File
Inappropriate Prescribing
Polypharmacy
Dementia
Primary Health Care
Cross-Sectional Studies
4 Citations (Scopus)
223 Downloads (Pure)
Open Access
File
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Dementia
Quality of Life
Blood Vessels
Polypharmacy
2015
6 Citations (Scopus)

Age-Related Macular Degeneration-Associated Genes in Alzheimer Disease

Williams, M. A., McKay, G. J., Carson, R., Craig, D., Silvestri, G. & Passmore, P., Dec 2015, In : The American Journal of Geriatric Psychiatry. 23, 12, p. 1290-1296 6 p.

Research output: Contribution to journalArticle

Macular Degeneration
Alzheimer Disease
Single Nucleotide Polymorphism
Haplotypes
Genes
301 Downloads (Pure)

Aspirin and anti-inflammatory drugs for the prevention of dementia

Jordan, F., McGuinness, B., Murphy, K., Passmore, P., Kelly, J. P. & Devane, D., 08 Jan 2015, In : Cochrane Database of Systematic Reviews. 2015, 1, p. 1-12

Research output: Contribution to journalArticle

Open Access
File
Non-Steroidal Anti-Inflammatory Agents
Primary Prevention
Secondary Prevention
Aspirin
Dementia
1 Citation (Scopus)

Blood type gene locus has no influence on ACE association with Alzheimer's disease

Braae, A., Medway, C., Carrasquillo, M., Younkin, S., Alzheimer's Research UK (ARUK) Consortium, Kehoe, P. G., Morgan, K., Passmore, P., Craig, D., Johnston, J. & McGuinness, B., 01 Apr 2015, In : Neurobiology of Aging. 36, 4, p. 1767.e1-1767.e2

Research output: Contribution to journalArticle

Peptidyl-Dipeptidase A
Alzheimer Disease
Genes
Genetic Predisposition to Disease
Blood Group Antigens
105 Citations (Scopus)

Common polygenic variation enhances risk prediction for Alzheimer's disease.

Escott-Price, V., Sims, R., Bannister, C., Harold, D., Vronskaya, M., Majounie, E., Badarinarayan, N., Morgan, K., Passmore, P., Holmes, C., Powell, J., Brayne, C., Gill, M., Mead, S., Goate, A., Cruchaga, C., Lambert, J-C., Van Dujin, C., Maier, W., Ramirez, A. & 7 others, Holmans, P., Jones, L., Hardy, J., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., Dec 2015, In : Brain. 138, p. 3673-84 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Genomics
Area Under Curve
Logistic Models
Genotype
101 Citations (Scopus)

Convergent genetic and expression data implicate immunity in Alzheimer's disease

Jones, L., Lambert, J-C., Wang, L-S., Choi, S-H., Harold, D., Vedernikov, A., Escott-Price, V., Stone, T., Richards, A., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Gerrish, A., Craig, D., Johnston, J. A., McGuinness, B., Todd, S. & Passmore, P., Jun 2015, In : Alzheimers & dementia. 11, 6, p. 658-671 14 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
76 Downloads (Pure)

Dementia

Cunningham, E. L., McGuinness, B., Herron, B. & Passmore, A. P., May 2015, In : Ulster Medical Journal. 84, 2, p. 79-87

Research output: Contribution to journalArticle

Open Access
File
Dementia
Memantine
Lewy Body Disease
Northern Ireland
Frontotemporal Dementia
11 Citations (Scopus)
214 Downloads (Pure)
Open Access
File
Feasibility Studies
Dementia
Consensus
Nursing Homes
Northern Ireland
15 Citations (Scopus)
255 Downloads (Pure)
Open Access
File
Polypharmacy
Primary Health Care
Pharmacists
General Practitioners
Pharmacies
6 Citations (Scopus)

Plasma Complement factor H in Alzheimer's Disease.

Williams, M. A., Haughton, D., Stevenson, M., Craig, D., Passmore, A. P. & Silvestri, G., 2015, In : Journal of Alzheimer's disease : JAD. 45, 2, p. 369-372 4 p.

Research output: Contribution to journalArticle

Complement Factor H
Alzheimer Disease
Biomarkers
Complement Activation
Immunodiffusion
13 Citations (Scopus)
235 Downloads (Pure)
Open Access
File
Cluster Analysis
Dementia
Aptitude
Cognitive Dysfunction
Education
5 Citations (Scopus)
Lewy Bodies
Alzheimer Disease
Brain
Genotype
Ions
3 Citations (Scopus)

Reciting the months of the year backwards: what is a 'normal' score?

Cunningham, EL., Passmore, AP., McAuley, DF. & McGuinness, B., May 2015, In : Age and Ageing. 44, 3, p. 537-538 2 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
219 Downloads (Pure)

Retinal microvascular network attenuation in Alzheimer's disease

Williams, M. A., McGowan, A. J., Cardwell, C. R., Cheung, C. Y., Craig, D., Passmore, P., Silvestri, G., Maxwell, A. P. & McKay, G. J., Jun 2015, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 1, 2, p. 229-235 7 p.

Research output: Contribution to journalArticle

Open Access
File
Microvessels
Social Adjustment
Fractals
Alzheimer Disease
Odds Ratio
47 Citations (Scopus)
233 Downloads (Pure)
Open Access
File
Plasma (human)
Metabolomics
Polyamines
metabolomics
Alzheimer disease
2014
30 Citations (Scopus)

Age-Associated Changes of Brain Copper, Iron, and Zinc in Alzheimer's Disease and Dementia with Lewy Bodies

Graham, S. F., Nasaruddin, M. B., Carey, M., Holscher, C., McGuinness, B., Kehoe, P. G., Love, S., Passmore, P., Elliott, C. T., Meharg, A. A. & Green, B. D., 13 Oct 2014, In : Journal of Alzheimer's disease : JAD. 42, 4, p. 1407-1413

Research output: Contribution to journalArticle

Lewy Bodies
Zinc
Copper
Alzheimer Disease
Iron
8 Citations (Scopus)

Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

Proitsi, P., Lupton, M. K., Velayudhan, L., Hunter, G., Newhouse, S., Lin, K., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Craig, D., Todd, S., Johnston, J. A., McGuinness, B., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Passmore, P. A., Sims, R. & 6 others, Williams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S. & Powell, J. F., Dec 2014, In : Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Alzheimer Disease
Alleles
Genotype
Odds Ratio
22 Citations (Scopus)

Assessment of factors that influence physician decision making regarding medication use in patients with dementia at the end of life

Parsons, C., McCorry, N., Murphy, K., Byrne, S., O'Sullivan, D., O'Mahony, D., Passmore, P., Patterson, S. & Hughes, C., Mar 2014, In : International Journal of Geriatric Psychiatry. 29, 3, p. 281-290

Research output: Contribution to journalArticle

Dementia
Decision Making
Physicians
Northern Ireland
Ireland