• Room 01.020 - School of Biological Sciences 19 Chlorine Gardens

    United Kingdom

Accepting PhD Students

1993 …2019
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Personal profile

Research Interests

Our research strategically focuses on deciphering the molecular mechanisms linking nutritional signalling (e.g. high-fat/high-carbohydrate diet and functional foods) with the onset of chronic metabolic disease, including diabetes, non-alcoholic fatty liver disease, cardiovascular disease and inflammatory bowel disease.

We employ a wide range of laboratory approaches from in vivo physiology to molecular biology and cell culture, such as genetically engineered animal models, Crispr/cas9 gene editing, single cell RNA-sequencing and microRNA profiling, to investigate the underlying molecular mechanisms that link lipid/carbohydrate metabolism and gut microbiomes with the pathogenesis of metabolic syndrome. We further investigate the therapeutic potentials of functional food (i.e. Fenugreek) and identify pharmaceutical targets that may lend supports for the prevention and treatment of diabetes, non-alcoholic fatty liver disease and cardiovascular disease. 

Fingerprint Dive into the research topics where Qiaozhu Su is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Liver Medicine & Life Sciences
Insulin Resistance Medicine & Life Sciences
VLDL Lipoproteins Medicine & Life Sciences
Hyperlipidemias Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Carrier Proteins Medicine & Life Sciences
Trigonella Medicine & Life Sciences
Endoplasmic Reticulum Stress Medicine & Life Sciences

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Research Output 1993 2019

  • 21 Article
  • 11 Meeting abstract
  • 6 Review article
  • 1 Chapter (peer-reviewed)

Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Metabolic Syndrome

Su, Q., Mar 2019, Handbook of Mitochondrial Dysfunction . Routledge, Taylor and Francis group, p. 409-422 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Oxidative Stress
Homeostasis
Mitochondria
Sirtuins
Unfolded Protein Response

Bioactive Compounds in Fenugreek Ameliorate ER Stress and VLDL Overproduction via the Mediation of Insig Signaling

Khound, R. & Su, Q., 12 Mar 2018, In : Arteriosclerosis Thrombosis and Vascular Biology. 38, Suppl_1, p. A178 1 p.

Research output: Contribution to journalMeeting abstract

Trigonella
Endoplasmic Reticulum Stress
Seeds
Liver
Sterol Regulatory Element Binding Protein 1
13 Citations (Scopus)

MicroRNAs and Hedgehog Signaling in the Pathogenesis of Progressive Liver Injury from NAFLD to Fibrosis

Cheng, X. & Su, Q., 12 Mar 2018, In : Arteriosclerosis Thrombosis and Vascular Biology. 38, Suppl_1, p. A601 1 p.

Research output: Contribution to journalMeeting abstract

Hedgehogs
MicroRNAs
Fibrosis
Liver Cirrhosis
Liver
12 Citations (Scopus)

MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis

Su, Q., Kumar, V., Sud, N. & Mahato, R. I., Apr 2018, In : Advanced Drug Delivery Reviews. 129, p. 54-63 10 p.

Research output: Contribution to journalReview article

MicroRNAs
Liver Cirrhosis
Liver
Wounds and Injuries
Hepatocytes
2 Citations (Scopus)

Novel peptide dermaseptin‐PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling

Long, Q., Li, L., Wang, H., Li, M., Wang, L., Zhou, M., Su, Q., Chen, T. & Wu, Y., 21 Nov 2018, In : Journal of Cellular and Molecular Medicine. 23, 2, p. 1300-1312 13 p.

Research output: Contribution to journalArticle

Open Access
File
Apoptosis
Peptides
Cell Membrane
Anura
Neoplasms

Activities 2014 2019

British Journal of Nutrition (Journal)

Qiaozhu Su (Peer reviewer)
21 Apr 2019

Activity: Publication peer-review and editorial work typesPublication peer-review

The Journal of Nutrition (Journal)

Qiaozhu Su (Peer reviewer)
22 Jan 2018

Activity: Publication peer-review and editorial work typesPublication peer-review

MicroRNA-378 in metabolic inflammatory stress and hepatic insulin resistance.

Qiaozhu Su (Invited speaker)
23 Aug 2017

Activity: Talk or presentation typesInvited or keynote talk at national or international conference

International Journal of Obesity (Journal)

Qiaozhu Su (Peer reviewer)
23 Oct 2017

Activity: Publication peer-review and editorial work typesPublication peer-review