20102019

Research output per year

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Research Output

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Coll, R. C., Hill, J. R., Day, C. J., Zamoshnikova, A., Boucher, D., Massey, N. L., Chitty, J. L., Fraser, J. A., Jennings, M. P., Robertson, A. A. B. & Schroder, K., 01 Jun 2019, In : Nature Chemical Biology. 15, p. 556–559

Research output: Contribution to journalArticle

Open Access
File
  • 24 Citations (Scopus)
    178 Downloads (Pure)

    A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

    Coll, R. C., Robertson, A. A. B., Chae, J. J., Higgins, S. C., Muñoz-Planillo, R., Inserra, M. C., Vetter, I., Dungan, L. S., Monks, B. G., Stutz, A., Croker, D. E., Butler, M. S., Haneklaus, M., Sutton, C. E., Núñez, G., Latz, E., Kastner, D. L., Mills, K. H. G., Masters, S. L., Schroder, K. & 2 others, Cooper, M. A. & O'Neill, L. A. J., Mar 2015, In : Nature Medicine. 21, 3, p. 248-55 8 p.

    Research output: Contribution to journalArticle

    Open Access
  • 696 Citations (Scopus)

    Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

    Boucher, D., Monteleone, M., Coll, R. C., Chen, K. W., Ross, C. M., Teo, J. L., Gomez, G. A., Holley, C. L., Bierschenk, D., Stacey, K. J., Yap, A. S., Bezbradica, J. S. & Schroder, K., 01 Mar 2018, In : Journal of Experimental Medicine. 215, 3, p. 827-840

    Research output: Contribution to journalArticle

    Open Access
    File
  • 46 Citations (Scopus)
    8 Downloads (Pure)

    Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals

    Bezbradica, J. S., Coll, R. C. & Schroder, K., 01 Jan 2017, In : Cellular and Molecular Immunology. 14, 1, p. 118-126 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 15 Citations (Scopus)
    1 Downloads (Pure)

    Questions and controversies in innate immune research: what is the physiological role of NLRP3?

    Coll, RC., O’Neill, LAJ. & Schroder, K., 04 Apr 2016, In : Cell death discovery.

    Research output: Contribution to journalReview article

    Open Access
    File
    69 Downloads (Pure)

    Prizes

    Research Australia Griffith University Discovery Award

    Rebecca Coll (Recipient), 16 Nov 2016

    Prize: Prize (including medals and awards)

  • Young Investigator Award

    Rebecca Coll (Recipient), 2012

    Prize: Prize (including medals and awards)

  • Best Science Bite at the Lorne Infection and Immunity Conference 2019

    Rebecca Coll (Recipient), 22 Feb 2019

    Prize: Prize (including medals and awards)

  • Activities

    Inflammasome Therapeutics Summit: Reviewing the Basic Biology & Mechanisms of Action for the Inflammasome

    Rebecca Coll (Invited speaker)
    30 Oct 2019

    Activity: Talk or presentation typesInvited or keynote talk at national or international conference

    Greater Manchester Immunology Group seminar series

    Rebecca Coll (Invited speaker)
    24 Oct 2019

    Activity: Talk or presentation typesInvited talk

    TCD Biochemical Society seminar series

    Rebecca Coll (Invited speaker)
    14 Nov 2019

    Activity: Talk or presentation typesInvited talk

    Immunology & Global Health seminar series

    Rebecca Coll (Invited speaker)
    22 Oct 2019

    Activity: Talk or presentation typesInvited talk

    World Congress on Inflammation Afternoon Symposia 5T2: Mechanisms of Inflammation & New Pharmacological Targets

    Rebecca Coll (Invited speaker)
    17 Sep 2019

    Activity: Talk or presentation typesInvited or keynote talk at national or international conference