• Room 01.060 - CEM

    United Kingdom

Accepting PhD Students

20102019
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Fingerprint Dive into the research topics where Rebecca Coll is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Inflammasomes Medicine & Life Sciences
Interleukin-1 Medicine & Life Sciences
Caspase 1 Medicine & Life Sciences
Chemical activation Chemical Compounds
Inflammation Medicine & Life Sciences
Type 2 Diabetes Mellitus Medicine & Life Sciences
Macrophages Medicine & Life Sciences
Cryopyrin-Associated Periodic Syndromes Medicine & Life Sciences

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Research Output 2010 2019

16 Citations (Scopus)
66 Downloads (Pure)

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Coll, R. C., Hill, J. R., Day, C. J., Zamoshnikova, A., Boucher, D., Massey, N. L., Chitty, J. L., Fraser, J. A., Jennings, M. P., Robertson, A. A. B. & Schroder, K., 01 Jun 2019, In : Nature Chemical Biology. 15, p. 556–559

Research output: Contribution to journalArticle

Open Access
File
Inflammasomes
Hydrolysis
Adenosine Triphosphate
666 Citations (Scopus)

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Coll, R. C., Robertson, A. A. B., Chae, J. J., Higgins, S. C., Muñoz-Planillo, R., Inserra, M. C., Vetter, I., Dungan, L. S., Monks, B. G., Stutz, A., Croker, D. E., Butler, M. S., Haneklaus, M., Sutton, C. E., Núñez, G., Latz, E., Kastner, D. L., Mills, K. H. G., Masters, S. L., Schroder, K. & 2 others, Cooper, M. A. & O'Neill, L. A. J., Mar 2015, In : Nature Medicine. 21, 3, p. 248-55 8 p.

Research output: Contribution to journalArticle

Open Access
Cryopyrin-Associated Periodic Syndromes
Inflammasomes
Molecules
Multiple Sclerosis
Chemical activation
43 Citations (Scopus)
7 Downloads (Pure)

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

Boucher, D., Monteleone, M., Coll, R. C., Chen, K. W., Ross, C. M., Teo, J. L., Gomez, G. A., Holley, C. L., Bierschenk, D., Stacey, K. J., Yap, A. S., Bezbradica, J. S. & Schroder, K., 01 Mar 2018, In : Journal of Experimental Medicine. 215, 3, p. 827-840

Research output: Contribution to journalArticle

Open Access
File
Inflammasomes
Caspase 1
Holoenzymes
Dimerization
Cell Size
14 Citations (Scopus)
1 Downloads (Pure)

Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals

Bezbradica, J. S., Coll, R. C. & Schroder, K., 01 Jan 2017, In : Cellular and Molecular Immunology. 14, 1, p. 118-126 9 p.

Research output: Contribution to journalArticle

Open Access
File
Inflammasomes
Macrophages
Nigericin
Bacterial Toxins
Wounds and Injuries
44 Downloads (Pure)

Questions and controversies in innate immune research: what is the physiological role of NLRP3?

Coll, RC., O’Neill, LAJ. & Schroder, K., 04 Apr 2016, In : Cell death discovery.

Research output: Contribution to journalReview article

Open Access
File

Prizes

Research Australia Griffith University Discovery Award

Rebecca Coll (Recipient), 16 Nov 2016

Prize: Prize (including medals and awards)

patent

Young Investigator Award

Rebecca Coll (Recipient), 2012

Prize: Prize (including medals and awards)

candidacy
poster
student

Best Science Bite at the Lorne Infection and Immunity Conference 2019

Rebecca Coll (Recipient), 22 Feb 2019

Prize: Prize (including medals and awards)

Bites and Stings
Immunity
Research Personnel
Infection

Activities 2013 2019

Inflammasome Therapeutics Summit: Reviewing the Basic Biology & Mechanisms of Action for the Inflammasome

Rebecca Coll (Invited speaker)
30 Oct 2019

Activity: Talk or presentation typesInvited or keynote talk at national or international conference

Greater Manchester Immunology Group seminar series

Rebecca Coll (Invited speaker)
24 Oct 2019

Activity: Talk or presentation typesInvited talk

TCD Biochemical Society seminar series

Rebecca Coll (Invited speaker)
14 Nov 2019

Activity: Talk or presentation typesInvited talk

Immunology & Global Health seminar series

Rebecca Coll (Invited speaker)
22 Oct 2019

Activity: Talk or presentation typesInvited talk

World Congress on Inflammation Afternoon Symposia 5T2: Mechanisms of Inflammation & New Pharmacological Targets

Rebecca Coll (Invited speaker)
17 Sep 2019

Activity: Talk or presentation typesInvited or keynote talk at national or international conference