Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Projects
- 3 Active
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R1365CNR: Development of a Chemoproteomics Centre of Excellence: A Prosperity Partnership for Drug Discovery in Northern Ireland
Scott, C. (PI), Coll, R. (CoI), Collins, B. (CoI), Graham, B. (CoI) & Longley, D. (CoI)
08/11/2023 → …
Project: Research
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R1127BSC: Establishment of mass spectrometry based proteomic capabilities at Queen's University Belfast
Graham, B. (PI), Coll, R. (CoI), Collins, B. (CoI), Graham, C. (CoI), Huws, S. (CoI), Malinova, D. (CoI), McMullan, G. (CoI), Mousley, A. (CoI), Panov, K. (CoI), Quinn, B. (CoI) & Schroeder, G. N. (CoI)
04/07/2023 → …
Project: Research
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R1544CEM: Investigating the thermal biology of inflammasomes – is NLRP3 a thermosensor?
Coll, R. (PI), Collins, B. (CoI) & Margariti, A. (CoI)
25/06/2021 → …
Project: Research
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MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
Coll, R. C., Hill, J. R., Day, C. J., Zamoshnikova, A., Boucher, D., Massey, N. L., Chitty, J. L., Fraser, J. A., Jennings, M. P., Robertson, A. A. B. & Schroder, K., 01 Jun 2019, In: Nature Chemical Biology. 15, p. 556–559Research output: Contribution to journal › Article › peer-review
Open AccessFile627 Citations (Scopus)3500 Downloads (Pure) -
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Coll, R. C., Robertson, A. A. B., Chae, J. J., Higgins, S. C., Muñoz-Planillo, R., Inserra, M. C., Vetter, I., Dungan, L. S., Monks, B. G., Stutz, A., Croker, D. E., Butler, M. S., Haneklaus, M., Sutton, C. E., Núñez, G., Latz, E., Kastner, D. L., Mills, K. H. G., Masters, S. L. & Schroder, K. & 2 others, , Mar 2015, In: Nature Medicine. 21, 3, p. 248-55 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2018 Citations (Scopus) -
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
Boucher, D., Monteleone, M., Coll, R. C., Chen, K. W., Ross, C. M., Teo, J. L., Gomez, G. A., Holley, C. L., Bierschenk, D., Stacey, K. J., Yap, A. S., Bezbradica, J. S. & Schroder, K., 01 Mar 2018, In: Journal of Experimental Medicine. 215, 3, p. 827-840Research output: Contribution to journal › Article › peer-review
Open AccessFile402 Citations (Scopus)163 Downloads (Pure) -
Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals
Bezbradica, J. S., Coll, R. C. & Schroder, K., 01 Jan 2017, In: Cellular and Molecular Immunology. 14, 1, p. 118-126 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Citations (Scopus)60 Downloads (Pure) -
Questions and controversies in innate immune research: what is the physiological role of NLRP3?
Coll, R., O’Neill, L. & Schroder, K., 04 Apr 2016, In: Cell death discovery.Research output: Contribution to journal › Review article › peer-review
Open AccessFile50 Citations (Scopus)173 Downloads (Pure)
Prizes
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Research Australia Griffith University Discovery Award
Coll, R. (Recipient), 16 Nov 2016
Prize: Prize (including medals and awards)
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2021 ICIS Regeneron New Investigator Award Winner for Excellence in Cytokine & Interferon Research
Coll, R. (Recipient), 2021
Prize: Prize (including medals and awards)
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Best Science Bite at the Lorne Infection and Immunity Conference 2019
Coll, R. (Recipient), 22 Feb 2019
Prize: Prize (including medals and awards)
Activities
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Inflammasome Therapeutics Summit: Reviewing the Basic Biology & Mechanisms of Action for the Inflammasome
Coll, R. (Invited speaker)
30 Oct 2019Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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Greater Manchester Immunology Group seminar series
Coll, R. (Invited speaker)
24 Oct 2019Activity: Talk or presentation types › Invited talk
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TCD Biochemical Society seminar series
Coll, R. (Invited speaker)
14 Nov 2019Activity: Talk or presentation types › Invited talk
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Immunology & Global Health seminar series
Coll, R. (Invited speaker)
22 Oct 2019Activity: Talk or presentation types › Invited talk
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World Congress on Inflammation Afternoon Symposia 5T2: Mechanisms of Inflammation & New Pharmacological Targets
Coll, R. (Invited speaker)
17 Sept 2019Activity: Talk or presentation types › Invited or keynote talk at national or international conference