Rebecca Coll

Academic Non-Clinical, School of Medicine, Dentistry and Biomedical Sciences
Academic Non-Clinical, Wellcome-Wolfson Institute for Experimental Medicine

https://orcid.org/0000-0002-7359-6023

Phone+44 (0)28 9097 6473
Emailr.coll@qub.ac.uk

Room 01.060 - CEM
United Kingdom

Accepting PhD Students

If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Rebecca Coll is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

10 Similar Profiles

Inflammasomes Medicine & Life Sciences

Interleukin-1 Medicine & Life Sciences

Caspase 1 Medicine & Life Sciences

Chemical activation Chemical Compounds

Inflammation Medicine & Life Sciences

Type 2 Diabetes Mellitus Medicine & Life Sciences

Macrophages Medicine & Life Sciences

Cryopyrin-Associated Periodic Syndromes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2010 2019

16 Article
6 Meeting abstract
6 Comment/debate
4 Abstract
7 More

16 Citations (Scopus)

66 Downloads (Pure)

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Coll, R. C., Hill, J. R., Day, C. J., Zamoshnikova, A., Boucher, D., Massey, N. L., Chitty, J. L., Fraser, J. A., Jennings, M. P., Robertson, A. A. B. & Schroder, K., 01 Jun 2019, In : Nature Chemical Biology. 15, p. 556–559

Research output: Contribution to journal › Article

Open Access

File

Inflammasomes

Hydrolysis

Adenosine Triphosphate

666 Citations (Scopus)

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Coll, R. C., Robertson, A. A. B., Chae, J. J., Higgins, S. C., Muñoz-Planillo, R., Inserra, M. C., Vetter, I., Dungan, L. S., Monks, B. G., Stutz, A., Croker, D. E., Butler, M. S., Haneklaus, M., Sutton, C. E., Núñez, G., Latz, E., Kastner, D. L., Mills, K. H. G., Masters, S. L., Schroder, K. & 2 others, Cooper, M. A. & O'Neill, L. A. J., Mar 2015, In : Nature Medicine. 21, 3, p. 248-55 8 p.

Research output: Contribution to journal › Article

Open Access

Cryopyrin-Associated Periodic Syndromes

Inflammasomes

Molecules

Multiple Sclerosis

Chemical activation

43 Citations (Scopus)

7 Downloads (Pure)

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

Boucher, D., Monteleone, M., Coll, R. C., Chen, K. W., Ross, C. M., Teo, J. L., Gomez, G. A., Holley, C. L., Bierschenk, D., Stacey, K. J., Yap, A. S., Bezbradica, J. S. & Schroder, K., 01 Mar 2018, In : Journal of Experimental Medicine. 215, 3, p. 827-840

Research output: Contribution to journal › Article

Open Access

File

Inflammasomes

Caspase 1

Holoenzymes

Dimerization

Cell Size

14 Citations (Scopus)

1 Downloads (Pure)