• Room 02.063 - CEM

    United Kingdom

Accepting PhD Students

PhD projects

Dr Medina offers research projects investigating vascular stem cell biology with focus on vascular ageing, cellular therapies, and diabetic vasculopathy.

20032020

Research output per year

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Research Output

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Abstract
2018

NADPH oxidase 4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes postischemic revascularisation

O'Neill, K., Campbell, D., Edgar, K., Moez, A., McLoughlin, K., O'Neill, C., Dellett, M., Hargey, C., Abudalo, R., Gill, E., Doyle, P., Toh, T., Khoo, J., McCrudden, C., Brunssen, C., Morawietz, H., Yoder, M. C., Stitt, A., Margariti, A., Medina, R. & 1 others, Grieve, D., 03 Feb 2018.

Research output: Contribution to conferenceAbstract

REDUCED PRO-ANGIOGENIC FUNCTION OF CORD BLOOD ENDOTHELIAL COLONY-FORMING CELLS IN HYPERGLYCAEMIA IS MEDIATED BY NOX4

Toh, T., O'Neill, K., Campbell, D., Yoder, M. C., Medina, R. & Grieve, D., 10 Sep 2018.

Research output: Contribution to conferenceAbstract

2015

CD362+ stromal stem cells (SSCs) promote revascularisation of the retina in a paracrine manner

Wong, V., Medina, R., Allen, L-D., Medina Acuna, C., Elliman, S., Loftus, P., O'Flynn, L. & Stitt, A., May 2015.

Research output: Contribution to conferenceAbstract

CD362+ stromal stem cells (SSCs) promote revascularisation of the retina in a paracrine manner.

Wong, V., Allen, L-D., Medina, R., Elliman, S. & Stitt, A., Apr 2015.

Research output: Contribution to conferenceAbstract

IL8 is a key component of the senescence-associated secretome in human endothelial colony-forming cells

Medina, R., O'Neill, C., Chambers, S., Guduric-Fuchs, J. & Stitt, A., Jul 2015, p. 2343-2344. 2 p.

Research output: Contribution to conferenceAbstract

Mir-130 increases the vasculogenic properties of human endothelial colony-forming cells under hypoxic conditions

Medina, R., Guduric-Fuchs, J., O'Neill, C., Chambers, S. & Stitt, A., 24 Jun 2015, p. F-1152, 444-5.

Research output: Contribution to conferenceAbstract

NADPH Oxidase Influences the Angiogenic Function of Endothelial Colony-Forming Cells

Campbell, DC., Medina, RJ., Stitt, AW. & Grieve, DJ., 08 Sep 2015, p. A10. 1 p.

Research output: Contribution to conferenceAbstract

The cellular density of Circulating Angiogenic Cells (CACs) dictates their angiogenic function

O'Neill, C., O'Doherty, M., Chambers, S., Guduric-Fuchs, J., Bottazzi, B., Medina, R. & Stitt, A., Apr 2015, p. 45.

Research output: Contribution to conferenceAbstract

The cellular density of Myeloid Angiogenic Cells (MACs) dictates their angiogenic function

O'Neill, C., O'Doherty, M., Chambers, S., Guduric-Fuchs, J., Bottazzi, B., Stitt, A. & Medina, R., Jun 2015.

Research output: Contribution to conferenceAbstract

Vasculogenic properties of endothelial colony forming cells (ECFCS) in hypoxia are regulated by MIR-130

Guduric-Fuchs, J., O'Neill, C., Bojdo, J., Chambers, S., Medina, R. & Stitt, A., Jun 2015, p. 30.

Research output: Contribution to conferenceAbstract

Vasoreparative potential of a unique population of stromal stem cells (SSCs) in ischaemic retina.

Wong, V., Allen, L-D., Medina, R., Elliman, S., Loftus, P. & Stitt, A., Jun 2015.

Research output: Contribution to conferenceAbstract

Vasoreparative potential of endothelial progenitor cells is enhanced by a novel erythropoietin (EPO) mimetic peptide.

O'Leary, O., Brazil, D., Brines, M., Cerami, A., Medina, R. & Stitt, A., Apr 2015.

Research output: Contribution to conferenceAbstract

2014

Characterization of Microvascular Changes and Retinal Pathology in a Mouse Model of Laser-induced Retinal Vein Occlusion

Reid, E., Bojdo, J., Lois, N., Medina, R. & Stitt, A., May 2014, p. 2092-2.

Research output: Contribution to conferenceAbstract

2013

Ex-vivo expansion of human endothelial progenitor cells leads to cellular senescence

Medina, R., Guduric-Fuchs, J., O'Neill, C., Chambers, S. & Stitt, A., 2013.

Research output: Contribution to conferenceAbstract

Isolation, expansion, and characterisation of human endothelial progenitors

Medina, R., Reid, E., Chambers, S., Guduric-Fuchs, J., O'Neill, C. & Stitt, A., 2013.

Research output: Contribution to conferenceAbstract

Senescence of endothelial progenitor cells during ex-vivo expansion is mediated by inflammatory cytokines

Medina, R., Guduric-Fuchs, J., Chambers, S., O'Neill, C. & Stitt, A., 2013.

Research output: Contribution to conferenceAbstract

Senescent endothelial progenitor cells show impaired vasoregenerative capacity in the ischemic retina

Reid, E., Medina, R., O'Doherty, M., O'Neill, C., Chambers, S., Guduric-Fuchs, J., Stitt, A. & Simpson, D., 2013, p. 4539-40.

Research output: Contribution to conferenceAbstract

2012

Early endothelial progenitor cells act as alternative M2 macrophages

O'Neill, C., Medina, R., Guduric-Fuchs, J., Simpson, D. & Stitt, A., 2012.

Research output: Contribution to conferenceAbstract

High glucose induces cellular dysfunction and premature senescence in endothelial progenitor cells (EPCs)

O'Neill, C., Medina, R., Chambers, S., O'Doherty, M. & Stitt, A., 2012, p. 65.

Research output: Contribution to conferenceAbstract

High Glucose induces cellular dysfunction and premature senescence in Endothelial Progenitor Cells (EPCs)

Stitt, A., Chambers, S., Medina, R., O'Neill, C. & O'Doherty, M., 2012.

Research output: Contribution to conferenceAbstract

The angiogenic potential of myeloid angiogenic cells (MACs) is regulated by cell density and associated alterations in the secretome

Medina, R., O'Neill, C., O'Doherty, M., Chambers, S., Guduric-Fuchs, J. & Stitt, A., 2012, p. 69.

Research output: Contribution to conferenceAbstract

2011

Activation of ACE2/Angiotensin-(1-7)/Mas Receptor Axis Enhances Vasoreparative Function of Diabetic Endothelial Progenitors

Jarajapu, Y. P. R., Bhatwadekar, A., Nikonova, E., Kent, D., Medina, R., Thut, C., Stitt, A., Boulton, M. E., Raizada, M. K. & Grant, M. B., 2011, p. 52(14):3576.

Research output: Contribution to conferenceAbstract

Circulating Angiogenic Cells (CACs) Promote Retinal Angiogenesis, A Response Mediated By Paracrine Release Of Interleukin-8 (IL-8)

O'Doherty, M., Medina, R., Knott, H., Guduric-Fuchs, J., Gardiner, T. & Stitt, A., 2011, p. 52(14):3184.

Research output: Contribution to conferenceAbstract

Early endothelial progenitor cells act as alternative M2 macrophages with pro-angiogenic properties mediated by IL-8.

O'Neill, C., Medina, R., Knott, H., Guduric-Fuchs, J., Gardiner, T., O'Doherty, M. & Stitt, A., 2011.

Research output: Contribution to conferenceAbstract

Endothelial progenitor cells contribute to vascular repair in the ischaemic retina

Medina, R., Guduric-Fuchs, J., O'Neill, C., O'Doherty, M. & Stitt, A., 2011.

Research output: Contribution to conferenceAbstract

Gene Expression Profiling In Endothelial Progenitor Cells (EPCs) Identifies Novel Transcripts Upregulated In Diabetic Patients Protected From Development Of Diabetic Retinopathy (DR)

S. Jadhao, C., Bhatwadekar, A., Yan, Y., Kent, D., Medina, R., Stitt, A., Thut, C., Smith, L., Boulton, M. E. & Grant, M. B., 2011, p. 52(14):2578.

Research output: Contribution to conferenceAbstract

2010

Outgrowth Endothelial Cells Potential for Reversing Ischaemic Retinopathy

Stitt, A., Medina, R., O'Neill, C., Humphries, M. & Gardiner, T., 2010, p. 51(13):3155.

Research output: Contribution to conferenceAbstract