Projects per year
Personal profile
Research Statement
The Stratified Medicine Group focuses on the following areas:
1) Characterisation of a molecular group in solid cancers that represents an innate immune response to DNA damage through the STING pathway.
2) Development of a biomarker for anti-angiogenic agents
3) Development of a biomarker for MEKK pathway activation
4) Identification of a prognostic biomarker for early prostate cancer
5) Development of new cell lines for pre-clinical modelling of ovarian and prostate cancer.
Other
Linked in Profile:
https://www.linkedin.com/in/profkennedy/
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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R3005CNR: Establishing a Precision Medicine Catapult Centre of Excellence in Northern Ireland
Salto-Tellez, M., Gonzalez de Castro, D., James, J., Kennedy, R., McArt, D. & Waugh, D.
01/12/2017 → …
Project: Research
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R6416CNR: Phase 1B/II study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor PF-02341066 in KRASMT and KRASWT (with aberrant c-MET) Colorectal Cancer Patients
Van Schaeybroeck, S., Johnston, P., Kennedy, R., Lawler, M., Longley, D., Salto-Tellez, M. & Wilson, R.
01/08/2013 → …
Project: Research
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R1005PMY: Artificial Intelligence Enables Clinical Decision Making in the Digital Healthcare Era
McArt, D., Kennedy, R. & Salto-Tellez, M.
12/02/2019 → 30/09/2020
Project: Research
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Dual prognostic classification of triple-negative breast cancer by DNA damage immune response and homologous recombination deficiency
Stecklein, S. R., Barlow, W., Pusztai, L., Timms, K., Kennedy, R., Logan, G. E., Seitz, R., Badve, S., Gökmen-Polar, Y., Porter, P., Linden, H., Tripathy, D., Hortobagyi, G. N., Godwin, A. K., Thompson, A., Hayes, D. F. & Sharma, P., 16 Nov 2023, In: JCO Precision Oncology. 7, e2300197.Research output: Contribution to journal › Article › peer-review
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Integrated multimodal analyses of DNA damage response and immune markers as predictors of response in metastatic triple-negative breast cancer in the TNT trial (NCT00532727)
Tovey, H., Sipos, O., Parker, J. S., Hoadley, K. A., Quist, J., Kernaghan, S., Kilburn, L., Salgado, R., Loi, S., Kennedy, R. D., Roxanis, I., Gazinska, P., Pinder, S. E., Bliss, J., Perou, C. M., Haider, S., Grigoriadis, A., Tutt, A. & Cheang, M. C. U., 15 Sep 2023, In: Clinical Cancer Research. 29, 18, p. 3691-3705 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
Pencik, J., Philippe, C., Schlederer, M., Atas, E., Pecoraro, M., Grund-Gröschke, S., Li, W., Tracz, A., Heidegger, I., Lagger, S., Trachtová, K., Oberhuber, M., Heitzer, E., Aksoy, O., Neubauer, H. A., Wingelhofer, B., Orlova, A., Witzeneder, N., Dillinger, T., Redl, E., & 35 others , 12 Aug 2023, In: Molecular Cancer. 22, 1, 133.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
A comprehensive systematic review and network meta-analysis: the role of anti-angiogenic agents in advanced epithelial ovarian cancer
Helali, A. E., Choi, H. C. W., Chan, W. W. L., Dickson, N., Siu, S. W. K., Chan, K. K., Ngan, H. Y. S., Ngan, R. K. C. & Kennedy, R. D., 09 Mar 2022, (Early online date) In: Scientific Reports. 12, p. 3803Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Downloads (Pure) -
Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer
Parkes, E. E., Savage, K. I., Lioe, T., Boyd, C., Halliday, S., Walker, S. M., Lowry, K., Knight, L., Buckley, N. E., Grogan, A., Logan, G. E., Clayton, A., Hurwitz, J., Kirk, S. J., Xu, J., Sidi, F. A., Humphries, M. P., Bingham, V., Ang, M., Askin, C., & 25 others , 01 Feb 2022, In: British Journal of Cancer. 126, 2, p. 247-258 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile90 Downloads (Pure)
Prizes
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Queen’s University of Belfast Vice Chancellor Award for Innovation
Kennedy, Richard (Recipient), 2013
Prize: Prize (including medals and awards)
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St Luke’s Medal for Cancer Research. Royal College of Medicine, Ireland
Kennedy, Richard (Recipient), 2015
Prize: Prize (including medals and awards)
Press/Media
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Targetable Immune Biology Found in Some Patients With Early-Stage Prostate Cancer
26/03/2018
1 Media contribution
Press/Media: Research
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Behind the Science. 30 minute TV programme on Cancer Research at QUB/Almac
13/12/2017
1 Media contribution
Press/Media: Public Engagement Activities
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High-tech disease profiling is the next stage in the fight against cancer
30/10/2017
1 Media contribution
Press/Media: Research
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A visit to the Doctor in 2013. Public lecture.
10/10/2017
1 item of Media coverage
Press/Media: Public Engagement Activities
Impact
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Development and Commercialization of a Technology Platform to Enable Biomarker Discovery and Validation
Richard Kennedy (Participant), Denis Harkin (Participant), Patrick Johnston (Participant), Alison Hosey (Participant), Julia Miskelly (Participant), Margaret Murray (Participant), Jennifer Quinn (Participant), Colin James (Participant), Jude Mulligan (Participant), Peter Daly (Participant), Paul Mullan (Participant), Julie Mussen (Participant), Ultan McDermott (Participant), Richard Wilson (Participant) & Daniel Longley (Participant)
Impact: Health Impact, Quality of Life Impact