Projects per year
Personal profile
Research Statement
The Stratified Medicine Group focuses on the following areas:
1) Characterisation of a molecular group in solid cancers that represents an innate immune response to DNA damage through the STING pathway.
2) Development of a biomarker for anti-angiogenic agents
3) Development of a biomarker for MEKK pathway activation
4) Identification of a prognostic biomarker for early prostate cancer
5) Development of new cell lines for pre-clinical modelling of ovarian and prostate cancer.
Other
Linked in Profile:
https://www.linkedin.com/in/profkennedy/
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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R3005CNR: Establishing a Precision Medicine Catapult Centre of Excellence in Northern Ireland
Salto-Tellez, M., Gonzalez de Castro, D., James, J., Kennedy, R., McArt, D. & Waugh, D.
01/12/2017 → …
Project: Research
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R6416CNR: Phase 1B/II study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor PF-02341066 in KRASMT and KRASWT (with aberrant c-MET) Colorectal Cancer Patients
Van Schaeybroeck, S., Johnston, P., Kennedy, R., Lawler, M., Longley, D., Salto-Tellez, M. & Wilson, R.
01/08/2013 → …
Project: Research
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R1005PMY: Artificial Intelligence Enables Clinical Decision Making in the Digital Healthcare Era
McArt, D., Kennedy, R. & Salto-Tellez, M.
12/02/2019 → 30/09/2020
Project: Research
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A comprehensive systematic review and network meta-analysis: the role of anti-angiogenic agents in advanced epithelial ovarian cancer
Helali, A. E., Choi, H. C. W., Chan, W. W. L., Dickson, N., Siu, S. W. K., Chan, K. K., Ngan, H. Y. S., Ngan, R. K. C. & Kennedy, R. D., 09 Mar 2022, (Early online date) In: Scientific Reports. 12, p. 3803Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Downloads (Pure) -
Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer
Parkes, E. E., Savage, K. I., Lioe, T., Boyd, C., Halliday, S., Walker, S. M., Lowry, K., Knight, L., Buckley, N. E., Grogan, A., Logan, G. E., Clayton, A., Hurwitz, J., Kirk, S. J., Xu, J., Sidi, F. A., Humphries, M. P., Bingham, V., Ang, M., Askin, C., & 25 others, 01 Feb 2022, In: British Journal of Cancer. 126, 2, p. 247-258 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile84 Downloads (Pure) -
A first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours
El Helali, A., Plummer, R., Jayson, G. C., Coyle, V. M., Drew, Y., Mescallado, N., Harris, N., Clamp, A. R., McCann, J., Swaisland, H., Kennedy, R. D., Cranston, A. N. & Wilson, R. H., 14 May 2022, (Early online date) In: British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Downloads (Pure) -
Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches
McCabe, N. H., Stevenson, L., Scanlon, E., Douglas, R., Kennedy, S., Keminer, O., Windshügel, B., Zisterer, D., Kennedy, R. D., Blayney, J. K. & Turkington, R. C., Aug 2022, In: Cancers. 14, 15, 3726.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Downloads (Pure) -
Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
Hollis, R. L., Meynert, A. M., Michie, C. O., Rye, T., Churchman, M., Hallas-Potts, A., Croy, I., McCluggage, W. G., Williams, A. R. W., Bartos, C., Iida, Y., Okamoto, A., Dougherty, B., Barrett, J. C., March, R., Matakidou, A., Roxburgh, P., Semple, C. A., Harkin, D. P., Kennedy, R., & 2 others, 15 Aug 2022, In: Clinical Cancer Research. 28, 16, p. 3546-3556 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Downloads (Pure)
Prizes
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Queen’s University of Belfast Vice Chancellor Award for Innovation
Kennedy, Richard (Recipient), 2013
Prize: Prize (including medals and awards)
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St Luke’s Medal for Cancer Research. Royal College of Medicine, Ireland
Kennedy, Richard (Recipient), 2015
Prize: Prize (including medals and awards)
Press/Media
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Targetable Immune Biology Found in Some Patients With Early-Stage Prostate Cancer
26/03/2018
1 Media contribution
Press/Media: Research
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Behind the Science. 30 minute TV programme on Cancer Research at QUB/Almac
13/12/2017
1 Media contribution
Press/Media: Public Engagement Activities
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High-tech disease profiling is the next stage in the fight against cancer
30/10/2017
1 Media contribution
Press/Media: Research
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A visit to the Doctor in 2013. Public lecture.
10/10/2017
1 item of Media coverage
Press/Media: Public Engagement Activities
Impact
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Development and Commercialization of a Technology Platform to Enable Biomarker Discovery and Validation
Richard Kennedy (Participant), Denis Harkin (Participant), Patrick Johnston (Participant), Alison Hosey (Participant), Julia Miskelly (Participant), Margaret Murray (Participant), Jennifer Quinn (Participant), Colin James (Participant), Jude Mulligan (Participant), Peter Daly (Participant), Paul Mullan (Participant), Julie Mussen (Participant), Ultan McDermott (Participant), Richard Wilson (Participant) & Daniel Longley (Participant)
Impact: Health Impact, Quality of Life Impact