Research output per year
Research output per year
- 1 - 50 out of 106 results
Search results
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2024
An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma
Baxter, M. A., Spender, L. C., Cairns, D., Walsh, S., Oparka, R., Porter, R. J., Bray, S., Skinner, G., King, S., Turbitt, J., Collinson, D., Miedzybrodzka, Z. H., Jellema, G., Logan, G., Kennedy, R. D., Turkington, R. C., McLean, M. H., Swinson, D., Grabsch, H. I. & Lord, S. & 3 others, , 13 May 2024, In: ESMO Open. 9, 5, 12 p., 103450.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
Ruthenium drug BOLD-100 regulates BRAFMT colorectal cancer cell apoptosis through AhR/ROS/ATR signaling axis modulation
Griffin, D., Carson, R., Moss, D., Sessler, T., Lavin, D., Tiwari, V., Karelia, S., Kennedy, R., Savage, K. I., McDade, S., Carie, A., Pankovich, J., Bazett, M. & Van Schaeybroeck, S., 04 Sept 2024, (Early online date) In: Molecular Cancer Research. 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF
Jurisic, A., Sung, P.-J., Wappett, M., Daubriac, J., Lobb, I. T., Kung, W.-W., Crawford, N., Page, N., Cassidy, E., Feutren-Burton, S., Rountree, J. S. S., Helm, M. D., O'Dowd, C. R., Kennedy, R. D., Gavory, G., Cranston, A. N., Longley, D. B., Jacq, X. & Harrison, T., 11 Apr 2024, In: Clinical and Translational Medicine. 14, 4, 22 p., e1648.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Downloads (Pure) -
2023
Dual prognostic classification of triple-negative breast cancer by DNA damage immune response and homologous recombination deficiency
Stecklein, S. R., Barlow, W., Pusztai, L., Timms, K., Kennedy, R., Logan, G. E., Seitz, R., Badve, S., Gökmen-Polar, Y., Porter, P., Linden, H., Tripathy, D., Hortobagyi, G. N., Godwin, A. K., Thompson, A., Hayes, D. F. & Sharma, P., 16 Nov 2023, In: JCO Precision Oncology. 7, e2300197.Research output: Contribution to journal › Article › peer-review
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Integrated multimodal analyses of DNA damage response and immune markers as predictors of response in metastatic triple-negative breast cancer in the TNT trial (NCT00532727)
Tovey, H., Sipos, O., Parker, J. S., Hoadley, K. A., Quist, J., Kernaghan, S., Kilburn, L., Salgado, R., Loi, S., Kennedy, R. D., Roxanis, I., Gazinska, P., Pinder, S. E., Bliss, J., Perou, C. M., Haider, S., Grigoriadis, A., Tutt, A. & Cheang, M. C. U., 15 Sept 2023, In: Clinical Cancer Research. 29, 18, p. 3691-3705 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)14 Downloads (Pure) -
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
Pencik, J., Philippe, C., Schlederer, M., Atas, E., Pecoraro, M., Grund-Gröschke, S., Li, W., Tracz, A., Heidegger, I., Lagger, S., Trachtová, K., Oberhuber, M., Heitzer, E., Aksoy, O., Neubauer, H. A., Wingelhofer, B., Orlova, A., Witzeneder, N., Dillinger, T. & Redl, E. & 35 others, , 12 Aug 2023, In: Molecular Cancer. 22, 1, 133.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)27 Downloads (Pure) -
2022
A comprehensive systematic review and network meta-analysis: the role of anti-angiogenic agents in advanced epithelial ovarian cancer
Helali, A. E., Choi, H. C. W., Chan, W. W. L., Dickson, N., Siu, S. W. K., Chan, K. K., Ngan, H. Y. S., Ngan, R. K. C. & Kennedy, R. D., 09 Mar 2022, (Early online date) In: Scientific Reports. 12, p. 3803Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)73 Downloads (Pure) -
Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer
Parkes, E. E., Savage, K. I., Lioe, T., Boyd, C., Halliday, S., Walker, S. M., Lowry, K., Knight, L., Buckley, N. E., Grogan, A., Logan, G. E., Clayton, A., Hurwitz, J., Kirk, S. J., Xu, J., Sidi, F. A., Humphries, M. P., Bingham, V., Ang, M. & Askin, C. & 25 others, , 01 Feb 2022, In: British Journal of Cancer. 126, 2, p. 247-258 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)132 Downloads (Pure) -
A first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours
El Helali, A., Plummer, R., Jayson, G. C., Coyle, V. M., Drew, Y., Mescallado, N., Harris, N., Clamp, A. R., McCann, J., Swaisland, H., Kennedy, R. D., Cranston, A. N. & Wilson, R. H., 14 May 2022, (Early online date) In: British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)75 Downloads (Pure) -
Identification of Src as a therapeutic target in oesophageal adenocarcinoma through functional genomic and high-throughput drug screening approaches
McCabe, N. H., Stevenson, L., Scanlon, E., Douglas, R., Kennedy, S., Keminer, O., Windshügel, B., Zisterer, D., Kennedy, R. D., Blayney, J. K. & Turkington, R. C., 30 Jul 2022, In: Cancers. 14, 15, 18 p., 3726.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)94 Downloads (Pure) -
Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
Hollis, R. L., Meynert, A. M., Michie, C. O., Rye, T., Churchman, M., Hallas-Potts, A., Croy, I., McCluggage, W. G., Williams, A. R. W., Bartos, C., Iida, Y., Okamoto, A., Dougherty, B., Barrett, J. C., March, R., Matakidou, A., Roxburgh, P., Semple, C. A., Harkin, D. P. & Kennedy, R. & 2 others, , 15 Aug 2022, In: Clinical Cancer Research. 28, 16, p. 3546-3556 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)69 Downloads (Pure) -
2021
In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer
Malla, S. B., Fisher, D. J., Domingo, E., Blake, A., Hassanieh, S., Redmond, K. L., Richman, S. D., Youdell, M., Walker, S. M., Logan, G. E., Chatzipli, A., Amirkhah, R., Humphries, M. P., Craig, S. G., McDermott, U., Seymour, M. T., Morton, D. G., Quirke, P., West, N. P. & Salto-Tellez, M. & 12 others, , 01 Jan 2021, In: Clinical Cancer Research. 27, p. 288-300 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Robustness of differential gene expression analysis of RNA-seq
Stupnikov, A., McInerney, C. E., Savage, K. I., McIntosh, S. A., Emmert-Streib, F., Kennedy, R., Salto-Tellez, M., Prise, K. M. & McArt, D. G., 26 May 2021, In: Computational and Structural Biotechnology Journal. 19, p. 3470-3481 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)235 Downloads (Pure) -
The clinical and molecular significance associated with STING signaling in breast cancer
Parkes, E. E., Humphries, M. P., Gilmore, E., Sidi, F. A., Bingham, V., Phyu, S. M., Craig, S., Graham, C., Miller, J., Griffin, D., Salto-Tellez, M., Madden, S., Kennedy, R. D., Bakhoum, S. F., McQuaid, S. & Buckley, N. E., 25 Jun 2021, In: npj Breast Cancer. 7, 1, 11 p., 81.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)90 Downloads (Pure) -
Ultra-Low DNA Input into Whole Genome Methylation Assays and Detection of Oncogenic Methylation and Copy Number Variants in Circulating Tumour DNA
S-CORT Consortium, 19 Feb 2021, In: Epigenomes. 5, 1, 6.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)133 Downloads (Pure) -
2020
ATM Kinase Inhibition Preferentially Sensitises PTEN-Deficient Prostate Tumour Cells to Ionising Radiation
Hanna, C., Dunne, V. L., Walker, S. M., Butterworth, K. T., McCabe, N., Waugh, D. J. J., Kennedy, R. D. & Prise, K. M., 30 Dec 2020, In: Cancers. 13, 1Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)68 Downloads (Pure) -
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer
Khawaja, H., Campbell, A., Roberts, J. Z., Javadi, A., O’Reilly, P., McArt, D., Allen, W. L., Majkut, J., Rehm, M., Bardelli, A., Di Nicolantonio, F., Scott, C. J., Kennedy, R., Vitale, N., Harrison, T., Sansom, O. J., Longley, D. B., Evergren, E. & Van Schaeybroeck, S., 29 Oct 2020, (Early online date) In: Cell death and disease. 11, 10, 18 p., 930.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)128 Downloads (Pure) -
Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours
Roberts, C., Strauss, V. Y., Kopijasz, S., Gourley, C., Hall, M., Montes, A., Abraham, J., Clamp, A., Kennedy, R., Banerjee, S., Folkes, L. K., Stratford, M. & Nicum, S., 18 Feb 2020, In: British Journal of Cancer. 122, 4, p. 483-490 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)28 Downloads (Pure) -
2019
A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer
Wilkinson, R., Burden, R., McDowell, S., McArt, D., McQuaid, S., Bingham, V., Williams, R., Cox, O., O'Connor, R., McCabe, N., Kennedy, R., Buckley, N. E. & Scott, C., 28 Jun 2019, In: Journal of Oncology.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)227 Downloads (Pure) -
Defining the molecular evolution of extrauterine high grade serous carcinoma
Beirne, J. P., McArt, D. G., Roddy, A., McDermott, C., Ferris, J., Buckley, N. E., Coulter, P., McCabe, N., Eddie, S. L., Dunne, P. D., O'Reilly, P., Gilmore, A., Feeney, L., Ewing, D. L., Drapkin, R. I., Salto-Tellez, M., Kennedy, R. D., Harley, I. J. G., McCluggage, W. G. & Mullan, P. B., 04 Sept 2019, In: Gynecologic Oncology. 155, 2, p. 305-317 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy
Gilmore, E., McCabe, N., Kennedy, R. & Parkes, E., 19 Jun 2019, In: Journal of Oncology.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)272 Downloads (Pure) -
High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum
Hollis, R. L., Churchman, M., Michie, C. O., Rye, T., Knight, L., McCavigan, A., Perren, T., Williams, A. R. W., McCluggage, W. G., Kaplan, R. S., Jayson, G. C., Oza, A., Harkin, D. P., Herrington, C. S., Kennedy, R. & Gourley, C., 15 Aug 2019, In: Cancer. 125, 16, p. 2772-2781 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)147 Downloads (Pure) -
Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma
Turkington, R., Knight, L., Blayney, J., Secrier, M., Douglas, R., Parkes, E., Sutton, E., Stevenson, L., McManus, D., Halliday, S., McCavigan, A., Logan, G., Walker, S., Steele, C., Perner, J., Bornscein, J., MacRae, S., Miremadi, A., McCarron, E. & McQuaid, S. & 10 others, , 09 Mar 2019, (Early online date) In: Gut. 68, 11, p. 1918-1927 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)342 Downloads (Pure) -
PDLIM2 is a marker of adhesion and β-catenin activity in triple-negative breast cancer
Cox, O., Edmunds, S., Simon-Keller, K., Li, B., Moran, B., Buckley, N. E., Bustamante-Garrido, M., Healy, N., O'Flanagan, C. H., Gallagher, W. M., Kennedy, R., Bernards, R., Caldos, C., Chin, S.-F., Marx, A. & O'Connor, R., 18 Mar 2019, In: Cancer Research. 79, 10, p. 2619Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)158 Downloads (Pure) -
Validation of the DNA damage immune response signature in patients with triple-negative breast cancer from the SWOG 9313c trial
Sharma, P., Barlow, W. E., Godwin, A. K., Parkes, E. E., Knight, L. A., Walker, S. M., Kennedy, R. D., Harkin, D. P., Logan, G. E., Steele, C. J., Lambe, S. M., Badve, S., Gökmen-Polar, Y., Pathak, H. B., Isakova, K., Linden, H. M., Porter, P., Pusztai, L., Thompson, A. M. & Tripathy, D. & 2 others, , 20 Dec 2019, In: Journal of Clinical Oncology. 37, 36, p. 3484-3492Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
2018
Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer
McGivern, N., El-Helali, A., Mullan, P., McNeish, I. A., Paul Harkin, D., Kennedy, R. D. & McCabe, N., 12 Jan 2018, In: Oncotarget. 9, 4, p. 4722-4736 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)277 Downloads (Pure) -
Analytical validation of a prognostic prostate cancer gene expression assay using formalin fixed paraffin embedded tissue
Medlow, P. W., Steele, C. J., McCavigan, A. M., Reardon, W., Brown, C. M., Lambe, S. M., Ishiy, F. A. A., Walker, S. M., Logan, G. E., Raji, O. Y., Berge, V., Katz, B., Kay, E. W., Sheehan, K., Watson, R. W., Harkin, D. P., Kennedy, R. D. & Knight, L. A., 27 Dec 2018, In: BMC Medical Genomics. 11, 1, 11 p., 125.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Downloads (Pure) -
Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer
Humphries, M., Hynes, S., Bingham, V., Cougot, D., James, J., Patel-Socha, F., Parkes, E., Blayney, J., O'Rorke, M., Irwin, G., McArt, D., Kennedy, R., Mullan, P., McQuaid, S., Salto-Tellez, M. & Buckley, N. E., 17 Dec 2018, In: Journal of Oncology. 2018, 14 p., 2937012.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Citations (Scopus)391 Downloads (Pure) -
FES-related tyrosine kinase activates the insulin-like growth factor-1 receptor at sites of cell adhesion
Stanicka, J., Rieger, L., O'Shea, S., Cox, O., Coleman, M., O'Flanagan, C., Addario, B., McCabe, N., Kennedy, R. & O'Connor, R., Jun 2018, In: Oncogene. 37, 23, p. 3131–3150Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)164 Downloads (Pure) -
Glucose Transporter 1 Expression as a Marker of Prognosis in Oesophageal Adenocarcinoma
Blayney, J. K., Cairns, L., Li, G., McCabe, N., Stevenson, L., Peters, C. J., Reid, N. B., Spence, V. J., Chisambo, C., McManus, D., James, J., McQuaid, S., Craig, S., Arthur, K., McArt, D., Ong, C.-A. J., Lao-Sirieix, P., Hamilton, P., Salto-Tellez, M. & Eatock, M. & 4 others, , 06 Apr 2018, (Early online date) In: Oncotarget.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)276 Downloads (Pure) -
The evolutionary landscape of colorectal tumorigenesis
The S:CORT Consortium, 31 Aug 2018, In: Nature Ecology and Evolution. 2, 10, p. 1661-1672 12 p.Research output: Contribution to journal › Article › peer-review
82 Citations (Scopus) -
The musculoskeletal consequences of latissmus dorsi breast reconstruction in women following mastectomy for breast cancer
Blackburn, N. E., Mc Veigh, J. G., Mc Caughan, E. M., Kennedy, R. D., McIntosh, S. A. & Wilson, I. M., 28 Aug 2018, In: PLoS ONE. 13, 8, 17 p., e0202859.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)325 Downloads (Pure) -
2017
Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
Parkes, E. E., Walker, S. M., Taggart, L. E., McCabe, N., Knight, L. A., Wilkinson, R., McCloskey, K., Buckley, N. E., Savage, K. I., Salto-Tellez, M., McQuaid, S., Harte, M. T., Mullan, P. B., Harkin, D. P. & Kennedy, R. D., 01 Jan 2017, In: Journal of the National Cancer Institute. 109, 1, djw199.Research output: Contribution to journal › Article › peer-review
Open AccessFile340 Citations (Scopus)13735 Downloads (Pure) -
Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology
Walker, S. M., Knight, L. A., McCavigan, A. M., Logan, G. E., Berge, V., Sherif, A., Pandha, H., Warren, A. Y., Davidson, C., Uprichard, A., Blayney, J. K., Price, B., Jellema, G. L., Steele, C. J., Svindland, A., McDade, S. S., Eden, C. G., Foster, C., Mills, I. G. & Neal, D. E. & 7 others, , 10 Apr 2017, (Early online date) In: European Urology. 72, 4, p. 509Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)373 Downloads (Pure) -
Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy
Jain, S., Lyons, C. A., Walker, S. M., McQuaid, S., Hynes, S., Mitchell, D., Pang, B., Logan, G. E., McCavigan, A. M., O'Rourke, D., McArt, D., McDade, S., Mills, I., Prise, K. M., Knight, L. A., Steele, C. J., Medlow, P. W., Berge, V., Katz, B. & Loblaw, D. A. & 5 others, , 10 Oct 2017, (Early online date) In: Annals of Oncology. 29, 1, p. 215Research output: Contribution to journal › Article › peer-review
Open AccessFile66 Citations (Scopus)275 Downloads (Pure) -
2016
A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer
Buckley, N. E., Haddock, P., De Matos Simoes, R., Parkes, E., Irwin, G., Emmert-Streib, F., McQuaid, S., Kennedy, R. & Mullan, P., 02 Mar 2016, In: Oncotarget. 7, 15, p. 19884 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)2077 Downloads (Pure) -
An Association of Cancer Physicians' strategy for improving services and outcomes for cancer patients
Baird, R., Banks, I., Cameron, D., Chester, J., Earl, H., Flannagan, M., Januszewski, A., Kennedy, R., Payne, S., Samuel, E., Taylor, H., Agarwal, R., Ahmed, S., Archer, C., Board, R., Carser, J., Copson, E., Cunningham, D., Coleman, R. & Dangoor, A. & 36 others, , 05 Jan 2016, In: ecancer medical science. 10, 608.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)344 Downloads (Pure) -
Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance)
Niedzwiecki, D., Frankel, W. L., Venook, A. P., Ye, X., Friedman, P. N., Goldberg, R. M., Mayer, R. J., Colacchio, T. A., Mulligan, J. M., Davison, T. S., O'Brien, E., Kerr, P., Johnston, P. G., Kennedy, R. D., Harkin, D. P., Schilsky, R. L., Bertagnolli, M. M., Warren, R. S. & Innocenti, F., 18 Jul 2016, (Early online date) In: Journal of Clinical Oncology. 34, 25, p. 3047 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Citations (Scopus)259 Downloads (Pure) -
Clinical Application of Poly(ADP-Ribose) Polymerase Inhibitors in High-Grade Serous Ovarian Cancer
Parkes, E. E. & Kennedy, R. D., 28 Mar 2016, (Early online date) In: The Oncologist.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Delivering a Research-Enabled Multistakeholder Partnership for Enhanced Patient Care at a Population Level: The Northern Ireland Comprehensive Cancer Program
Lawler, M., Gavin, A., Salto-Tellez, M., Kennedy, R. D., Van Schaeybroeck, S., Wilson, R. H., Harkin, D. P., Grayson, M., Boyd, R. E., Hamilton, P. W., McArt, D. G., James, J., Robson, T., Ladner, R. D., Prise, K. M., O'Sullivan, J. M., Harrison, T., Murray, L., Johnston, P. G. & Waugh, D. J., 01 Mar 2016, In: Cancer. 122, 5, p. 664-673 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)382 Downloads (Pure) -
IGF-1R inhibition sensitizes breast cancer cells to ATM-Related Kinase (ATR) inhibitor and cisplatin
O'Flanagan, C. H., O'Shea, S., Lyons, A., Fogarty, F. M., McCabe, N., Kennedy, R. D. & O'Connor, R., 27 Jul 2016, In: Oncotarget. 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)413 Downloads (Pure) -
Molecular Subtypes and Personalized Therapy in Metastatic Colorectal Cancer
Graham, D. M., Coyle, V. M., Kennedy, R. D. & Wilson, R. H., Jun 2016, In: Current Colorectal Cancer Reports. 12, 3, p. 141-150 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)605 Downloads (Pure) -
Prior knowledge transfer across transcriptional data sets and technologies using compositional statistics yields new mislabelled ovarian cell line
Blayney, J. K., Davison, T., McCabe, N., Walker, S., Keating, K., Delaney, T., Greenan, C., Williams, A. R., McCluggage, W. G., Capes-Davis, A., Harkin, D. P., Gourley, C. & Kennedy, R. D., 28 Jun 2016, (Early online date) In: Nucleic Acids Research. 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)290 Downloads (Pure) -
The role of PTEN as a cancer biomarker
McCabe, N., Kennedy, R. D. & Prise, K. M., 03 Mar 2016, In: Oncoscience. 3, 2, p. 54-5 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)285 Downloads (Pure) -
When the guardian becomes the enemy, targeting ATM in PTEN deficient cancers
McCabe, N., Walker, S. M. & Kennedy, R. D., 2016, In: Molecular & Cellular Oncology. 3, 1, 3 p., e1053595 .Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
2015
Clinical Tumor Staging of Adenocarcinoma of the Esophagus and Esophagogastric Junction
Turkington, R. C., Parkes, E., Kennedy, R. D., Eatock, M. M., Harrison, C., McCloskey, P. & Purcell, C., 20 Mar 2015, In: Journal of Clinical Oncology. 33, 9, p. 1088 1 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Integrated molecular pathology: the Belfast model
Salto-Tellez, M. & Kennedy, R. D., Dec 2015, In: Drug Discovery Today. 20, 12Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM
McCabe, N., Hanna, C., Walker, S. M., Gonda, D., Li, J., Wikstrom, K., Savage, K. I., Butterworth, K. T., Chen, C., Harkin, D. P., Prise, K. M. & Kennedy, R. D., 01 Jun 2015, In: Cancer Research. 75, 11, p. 2159-2165 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile58 Citations (Scopus)350 Downloads (Pure) -
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition
Shen, Y., Li, J., Nitta, M., Futalan, D., Steed, T., Treiber, J. M., Taich, Z., Stevens, D., Wykosky, J., Chen, H.-Z., Carter, B. S., Becher, O. J., Kennedy, R., Esashi, F., Sarkaria, J. N., Furnari, F. B., Cavenee, W. K., Desai, A. & Chen, C. C., 20 May 2015, In: Oncotarget. 6, 14, p. 11751-67 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)252 Downloads (Pure) -
PICan: An integromics framework for dynamic cancer biomarker discovery
McArt, D. G., Blayney, J. K., Boyle, D. P., Irwin, G. W., Moran, M., Hutchinson, R. A., Bankhead, P., Kieran, D., Wang, Y., Dunne, P. D., Kennedy, R. D., Mullan, P. B., Harkin, D. P., Catherwood, M. A., James, J. A., Salto-Tellez, M. & Hamilton, P. W., 01 Jun 2015, In: Molecular oncology. 9, 6, p. 1234-1240 7 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus)