Projects per year
Personal profile
Research Focus
I am a Reader in Medical Oncology at the Centre for Public Health, Queen’s University Belfast and an Honorary Consultant at the Northern Ireland Cancer Centre with an interest in oesophago-gastric and pancreatic cancer. Having graduated in medicine from Queen’s University Belfast I began specialty training in Medical Oncology in 2005. In 2007 I was awarded a Cancer Research UK Bobby Moore Clinical Research Fellowship to pursue a PhD in novel drug target discovery in colo-rectal cancer under the supervision of Professor Patrick Johnston. Following completion of my Phd I was appointed as an Academic Clinical Lecturer in the field of oesophago-gastric cancer and in 2013 became a Visiting Research Fellow at the Hutchison/MRC Cancer Unit, University of Cambridge, under the supervision of Professor Rebecca Fitzgerald. My work has been published in high impact journals and in 2014 I received the American Society of Clinical Oncology Merit Award. My principle research interests include oesophago-gastric and pancreatic cancer and the analysis of genomic datasets for the discovery of biomarkers for early detection, treatment response and biological insights of pre-malignant disease and cancer. These discoveries are being translated into clinical advances through the implementation of biomarker-led clinical trials. As part of the upper gastrointestinal cancer team at Queen’s University Belfast I seek to transform the care of oesophago-gastric and pancreatic cancer patients through the integration of laboratory discoveries, translational science and clinical research.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 2 Active
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R2698CNR: Exploiting the Immune Landscape of Oesophageal and Pancreatic Cancer
Turkington, R. (PI), Blayney, J. (CoI) & Savage, K. (CoI)
04/02/2020 → …
Project: Research
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R6547CNR: Training in Cancer Mechanisms and Therapeutics
Turkington, R. (PI) & Blayney, J. (CoI)
29/09/2016 → …
Project: Research
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An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma
Baxter, M. A., Spender, L. C., Cairns, D., Walsh, S., Oparka, R., Porter, R. J., Bray, S., Skinner, G., King, S., Turbitt, J., Collinson, D., Miedzybrodzka, Z. H., Jellema, G., Logan, G., Kennedy, R. D., Turkington, R. C., McLean, M. H., Swinson, D., Grabsch, H. I. & Lord, S. & 3 others, , 13 May 2024, In: ESMO Open. 9, 5, 12 p., 103450.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)12 Downloads (Pure) -
Disentangling oncogenic amplicons in esophageal adenocarcinoma
Ng, A. W. T., McClurg, D. P., Wesley, B., Zamani, S. A., Black, E., Miremadi, A., Giger, O., Hoopen, R. T., Devonshire, G., Redmond, A. M., Grehan, N., Jammula, S., Blasko, A., Li, X., Aparicio, S., Tavaré, S., Edwards, P. A. W., Grehan, N., Nutzinger, B. & Loreno, C. & 31 others, , 14 May 2024, In: Nature Communications. 15, 4074.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure) -
Immune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma: a translational analysis of the DEBIOC clinical trial
Scanlon, E., Lavery, A., Albraikat, M., Stevenson, L., Kennedy, C., Byrne, R., Walker, A., Mullan-Young, B., McManus, D. T., Virdee, P. S., Elhussein, L., Turbitt, J., Collinson, D., Miedzybrodzka, Z., Van Schaeybroeck, S., McQuaid, S., James, J. A., Craig, S. G., Blayney, J. K. & Petty, R. D. & 6 others, , Nov 2024, In: ESMO Open. 9, 11, 14 p., 103930.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Multicentre validation of CT grey-level co-occurrence matrix features for overall survival in primary oesophageal adenocarcinoma
O’Shea, R., Withey, S. J., Owczarczyk, K., Rookyard, C., Gossage, J., Godfrey, E., Jobling, C., Parsons, S. L., Skipworth, R. J. E., Goh, V., Crosby, T. D. L., Bartlett, F., Petty, R. D., Coleman, H., McManus, D., Turkington, R., Grabowska, A., Moorthy, K., Peters, C. J. & Hanna, G. B. & 31 others, , Oct 2024, In: European Radiology. 34, 10, p. 6919-6928 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
Multi-omic analysis of esophageal adenocarcinoma uncovers candidate therapeutic targets and cancer-selective posttranscriptional regulation
Robert O'Neill, J., Mayordomo, M. Y., Mitulović, G., Al Shboul, S., Bedran, G., Faktor, J., Hernychova, L., Uhrik, L., Gómez-Herranz, M., Kocikowski, M., Save, V., Vojtěšek, B., Arends, M. J., Hupp, T., Alfaro, J. A., Fitzgerald, R. C., Edwards, P. A. W., Grehan, N., Nutzinger, B. & Loreno, C. & 31 others, , 19 Jun 2024, In: Molecular and Cellular Proteomics. 23, 6, 100764.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure)
Prizes
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American Society of Clinical Oncology Merit Award- Donna Graham
Graham, D. (Recipient) & Turkington, R. (Recipient), 02 Jun 2017
Prize: Prize (including medals and awards)
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American Society of Clinical Oncology Merit Award- Eileen Parkes
Parkes, E. (Recipient) & Turkington, R. (Recipient), 02 Jun 2017
Prize: Prize (including medals and awards)
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Postgraduate Research Forum Oral Presentation Prize- Niamh McCabe
McCabe, N. (Recipient) & Turkington, R. (Recipient), 07 Nov 2019
Prize: Prize (including medals and awards)
Activities
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National Oncology Trainees Collaborative (NOTCH) Research Symposium
Turkington, R. (Invited speaker)
09 Mar 2023 → 10 Mar 2023Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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59th Irish Association for Cancer Research Conference 2023
Turkington, R. (Member of the organising committee)
22 Feb 2023 → 24 Feb 2023Activity: Participating in or organising an event types › Participation in conference
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DECIPHER clinical trial: Member of the Trial Steering Committee
Turkington, R. (Board member)
01 Feb 2023 → 10 Mar 2023Activity: Other activity types › Other
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PhD Examination- Elizabeth Cartwright at Royal Marsden Hospital, University of London
Turkington, R. (Examiner)
01 Feb 2023Activity: Examination types › PhD external examination
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Cancer Research UK (External organisation)
Turkington, R. (Board Member)
25 Jan 2023 → 10 Mar 2023Activity: Membership types › Membership of national or international committees and working groups
Press/Media
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Breakthrough Cancer Research: Launch of All-Ireland Cancer Network (All CaN) in Oesophageal Cancer
Coleman, H., Turkington, R., Johnson, B. T., Middleton, D., Kunzmann, A., Cairnduff, V., Hamilton, A., McManus, D., Reid, H., Dempster, M., Santin, O., Craig, S., Murray, D., Gavin, A., Bennett, K., Cardwell, C., Bennett, D., O’Sullivan, J., Hussey, J., McManus, D. & Bennett, D.
04/02/2023 → 05/02/2023
6 items of Media coverage
Press/Media: Research
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Launch of first All-Ireland Oesophageal Cancer Research Network
05/02/2023
1 Media contribution
Press/Media: Research
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Launch of Brian Conlon Family Foundation to support oesophageal cancer research
25/04/2022
1 Media contribution
Press/Media: Research
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Cancer Cases Undiagnosed due to Impact of Covid
08/02/2021
1 item of Media coverage
Press/Media: Research
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