Research output per year
Research output per year
- 1 - 50 out of 64 results
Search results
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2024
Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis: the EASI-SWITCH RCT
Coyle, V., Forde, C., Adams, R., Agus, A., Barnes, R., Chau, I., Clarke, M., Doran, A., Grayson, M., McAuley, D., McDowell, C., Phair, G., Plummer, R., Storey, D., Thomas, A., Wilson, R. & McMullan, R., 01 Mar 2024, In: Health Technology Assessment. 28, 14, p. 1-101 101 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Downloads (Pure) -
Early switch to oral antibiotic therapy in patients with low-risk neutropenic sepsis (EASI-SWITCH): a randomized non-inferiority trial
EASI-SWITCH Investigators, Jan 2024, In: Clinical Microbiology and Infection. 30, 1, p. 92-99 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)54 Downloads (Pure) -
2023
Analysis of exhaled breath to identify critically ill patients with ventilator‐associated pneumonia
Felton, T. W., Ahmed, W., White, I. R., van Oort, P., Rattray, N. J. W., Docherty, C., Bannard‐Smith, J., Morton, B., Welters, I., McMullan, R., Roberts, S. A., Goodacre, R., Dark, P. M. & Fowler, S. J., 03 Apr 2023, (Early online date) In: Anaesthesia.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)69 Downloads (Pure) -
biomArker-guided Duration of Antibiotic treatment in hospitalised Patients with suspecTed Sepsis (ADAPT-Sepsis): A protocol for a multicentre randomised controlled trial
Dark, P., Perkins, G. D., McMullan, R., McAuley, D., Gordon, A. C., Clayton, J., Mistry, D., Young, K., Regan, S., McGowan, N., Stevenson, M., Gates, S., Carlson, G. L., Walsh, T., Lone, N. I., Mouncey, P. R., Singer, M., Wilson, P., Felton, T. & Marshall, K. & 2 others, , 25 Apr 2023, (Early online date) In: Journal of the Intensive Care Society.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
BTS clinical statement on aspiration pneumonia
Simpson, A. J., Allen, J.-L., Chatwin, M., Crawford, H., Elverson, J., Ewan, V., Forton, J., McMullan, R., Plevris, J., Renton, K., Tedd, H., Thomas, R. & Legg, J., 01 Feb 2023, In: Thorax. 78, Suppl 1, p. 3–21Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
Cost-effectiveness of therapeutics for COVID-19 patients: a rapid review and economic analysis
Metry, A., Pandor, A., Ren, S., Shippam, A., Clowes, M., Dark, P., McMullan, R. & Stevenson, M., 31 Aug 2023, In: Health technology assessment (Winchester, England). 27, 14, p. 1-92 92 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)1026 Downloads (Pure) -
Modelling the gastrointestinal carriage of Klebsiella pneumoniae infections
Calderon-Gonzalez, R., Lee, A., Lopez-Campos, G., Hancock, S. J., Sa-Pessoa, J., Dumigan, A., McMullan, R., Campbell, E. L. & Bengoechea, J. A., 28 Feb 2023, In: mBio. 14, 1, 19 p., e03121-22.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)105 Downloads (Pure) -
2022
Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia [version 3; peer review: 2 approved]
Navapurkar, V., Bartholdson Scott, J., Maes, M., Hellyer, T. P., Higginson, E., Forrest, S., Pereira-Dias, J., Parmar, S., Heasman-Hunt, E., Polgarova, P., Brown, J., Titti, L., Smith, W. P., Scott, J., Rostron, A., Routledge, M., Sapsford, D., Török, M. E., McMullan, R. & Enoch, D. A. & 8 others, , 12 Oct 2022, In: Wellcome Open Research. 6, 256.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)58 Downloads (Pure) -
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis)
Scott, J., Trevi, L., McNeil, H., Ewen, T., Mawson, P., McDonald, D., Filby, A., Lall, R., Booth, K., Boschman, G., Melkebeek, V., Perkins, G., McMullan, R., McAuley, D. F., McCullagh, I. J., Walsh, T., Rostron, A., Shankar-Hari, M., Dark, P. & Simpson, A. J. & 2 others, , 09 Dec 2022, (Early online date) In: BMJ Open. 12, 12, e068321.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
2021
Reply to Aberegg and Wolfe
Loughlin, L., McAuley, D. F., Simpson, A. J. & McMullan, R., 15 Apr 2021, In: American Journal of Respiratory and Critical Care Medicine. 203, 8, p. 1044-1045 2 p.Research output: Contribution to journal › Article
Open AccessFile27 Downloads (Pure) -
Targeting Candida albicans in dual-species biofilms with antifungal treatment reduces Staphylococcus aureus and MRSA in vitro
Luo, Y., McAuley, D. F., Fulton, C. R., Sá Pessoa, J., McMullan, R. & Lundy, F. T., 08 Apr 2021, In: PLoS ONE. 16, 4, p. e0249547Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)139 Downloads (Pure) -
The utility of 16S rRNA gene sequencing on intraoperative specimens from intracranial infections: an 8-year study in a regional UK neurosurgical unit
Shaw, T. D., Curran, T., Cooke, S., McMullan, R. & Hunter, M., 20 Dec 2021, (Early online date) In: British journal of neurosurgery. p. 1-6Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)73 Downloads (Pure) -
2020
Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation
Hellyer, T. P., McAuley, D. F., Walsh, T. S., Anderson, N. H., Conway Morris, A., Singh, S., Dark, P., Roy, A. I., Perkins, G. D., McMullan, R., Emerson, L., Blackwood, B., Wright, S. E., Kefala, K., O'Kane, C., Baudouin, S. V., Paterson, R. W., Rostron, A. J., Agus, A. & Bannard-Smith, J. & 19 others, , Feb 2020, In: The Lancet Respiratory Medicine. 8, 2, p. 182-191 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile63 Citations (Scopus)191 Downloads (Pure) -
Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis (the EASI-SWITCH trial): study protocol for a randomised controlled trial
Forde, C., McMullan, R., Clarke, M., Wilson, R. H., Plummer, R., Grayson, M., McDowell, C., Agus, A., Doran, A., McAuley, D. F., Thomas, A. L., Barnes, R. A., Adams, R., Chau, I. & Coyle, V., 27 May 2020, In: Trials. 21, 1, 11 p., 431.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)136 Downloads (Pure) -
How to optimise duration of antibiotic treatment in patients with sepsis?
Hellyer, T. P., Mantle, T., McMullan, R. & Dark, P., 23 Nov 2020, In: BMJ (Clinical research ed.). 371, p. m4357Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)41 Downloads (Pure) -
Pulmonary Aspergillosis in Patients with Suspected Ventilator-associated Pneumonia in UK Intensive Care Units
Loughlin, L., Hellyer, T. P., White, P. L., McAuley, D. F., Conway Morris, A., Posso, R. B., Richardson, M. D., Denning, D. W., Simpson, A. J. & McMullan, R., 15 Oct 2020, In: American Journal of Respiratory and Critical Care Medicine. 202, 8Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Citations (Scopus)583 Downloads (Pure) -
2019
Individual risk factors and critical care unit effects on Invasive Candida Infection occurring in critical care units in the UK: A multilevel model
Patterson, L., McMullan, R. & Harrison, D. A., Sept 2019, In: Mycoses. 62, 9, p. 790-795 6 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
2018
Diagnostic accuracy of fungal PCR and β-d-glucan for detection of candidaemia: a preliminary evaluation
McKeating, C., White, P. L., Posso, R., Palmer, M., Johnson, E. & McMullan, R., May 2018, In: Journal of Clinical Pathology. 71, 5, p. 420-424 5 p.Research output: Contribution to journal › Article › peer-review
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Diagnostic accuracy of fungal PCR and β- D -glucan for detection of candidaemia: A preliminary evaluation
McKeating, C., White, P. L., Posso, R., Palmer, M., Johnson, E. & McMullan, R., 01 May 2018, In: Journal of Clinical Pathology. 71, 5, p. 420-424 5 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
The use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism.
Shaw, T., Fairley, D. J., Schneiders, T., Pathiraja, M., Hill, R. L. R., Werner, G., Elborn, J. & McMullan, R., 24 Feb 2018, (Early online date) In: European Journal of Clinical Microbiology and Infectious Diseases. p. 1-9Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)208 Downloads (Pure) -
2017
16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia
Conway Morris, A., Gadsby, N., McKenna, J. P., Hellyer, T. P., Dark, P., Singh, S., Walsh, T. S., McAuley, D. F., Templeton, K., Simpson, A. J. & McMullan, R., Nov 2017, In: Thorax. 72, 11, p. 1046-1048 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)280 Downloads (Pure) -
Peptoid Efficacy against Polymicrobial Biofilms Determined by Using Propidium Monoazide-Modified Quantitative PCR
Luo, Y., Bolt, H. L., Eggimann, G. A., McAuley, D. F., McMullan, R., Curran, T., Zhou, M., Jahoda, C., Cobb, S. L. & Lundy, F. T., 03 Jan 2017, In: ChemBioChem. 18, 1, p. 111-118 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)274 Downloads (Pure) -
The naturally occurring host defense peptide, LL-37, and its truncated mimetics KE-18 and KR-12 have selected biocidal and antibiofilm activities against Candida albicans, Staphylococcus aureus, and Escherichia coli in vitro
Luo, Y., McLean, D. T. F., Linden, G. J., McAuley, D. F., McMullan, R. & Lundy, F. T., 31 Mar 2017, In: Frontiers in Microbiology. 8, MAR, 544.Research output: Contribution to journal › Article › peer-review
Open AccessFile71 Citations (Scopus)381 Downloads (Pure) -
2016
Effectiveness of a biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use: protocol for a randomised controlled trial (VAPrapid-2): study protocol for a randomised controlled trial
Hellyer, T. P., Anderson, N. H., Parker, J., Dark, P., van den Broeck, T., Singh, S., McMullan, R., Agus, A., Emerson, L. M., Blackwood, B., Gossain, S., Walsh, T., Perkins, G., Conway Morris, A., McAuley, D. F. & Simpson, A. J., 16 Jul 2016, In: Trials. 17, 1, 8 p., 318.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)263 Downloads (Pure) -
Low-pathogenicity Mycoplasma spp. alter human monocyte and macrophage function and are highly prevalent among patients with ventilator-acquired pneumonia
Nolan, T. J., Gadsby, N. J., Hellyer, T. P., Templeton, K. E., McMullan, R., McKenna, J., Rennie, J., Robb, C. T., Walsh, T. S., Rossi, A. G., Conway Morris, A. & Simpson, A. J., 01 Jul 2016, In: Thorax. 71, 7, p. 594-600 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)237 Downloads (Pure) -
Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi – a systematic review and economic evaluation
Stevenson, M., Pandor, A., James, M.M.-S., Rafia, R., Uttley, L., Stevens, J., Sanderson, J., Wong, R., Perkins, G. D., McMullan, R. & Dark, P., Jun 2016, In: Health Technology Assessment. 20, 46, p. 1-246 274 p.Research output: Contribution to journal › Article › peer-review
File65 Citations (Scopus)802 Downloads (Pure) -
2015
Burden of fungal disease in Ireland
Dorgan, E., Denning, D. W. & McMullan, R., 01 Apr 2015, In: Journal of Medical Microbiology. 64, 4, p. 423-426 4 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia
Hellyer, T. P., Conway Morris, A., McAuley, D. F., Walsh, T. S., Anderson, N. H., Singh, S., Dark, P., Roy, A. I., Baudouin, S. V., Wright, S. E., Perkins, G. D., Kefala, K., Jeffels, M., McMullan, R., O'Kane, C. M., Spencer, C., Laha, S., Robin, N., Gossain, S. & Gould, K. & 10 others, , Jan 2015, In: Thorax. 70, 1, p. 41-47 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile53 Citations (Scopus)217 Downloads (Pure) -
Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review
Warhurst, G., Dunn, G., Chadwick, P., Blackwood, B., McAuley, D., Perkins, G. D., McMullan, R., Gates, S., Bentley, A., Young, D., Carlson, G. L. & Dark, P., May 2015, In: Health Technology Assessment. 19, 35Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)728 Downloads (Pure) -
2014
Aspergillus infection in pulmonary cavitating lesions with right atrial myxoma
Sharma, D., Dorgan, E., Douglas, H., Trouton, T., McMullan, R. & Parissis, H., Nov 2014, In: Asian cardiovascular & thoracic annals. 22, 9, p. 1090-1092 3 p.Research output: Contribution to journal › Article › peer-review
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Streptococcus bovis bacteraemia: an evaluation of the long-term effect on cardiac outcomes
Fitzmaurice, G. J., McKenna, A. J., Murphy, J., McMullan, R. & O'Donnell, M. E., Mar 2014, In: General Thoracic and Cardiovascular Surgery. 62, 3, p. 142-148 7 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
2013
Tea tree oil (5%) body wash versus standard care (Johnson's Baby Softwash) to prevent colonization with methicillin-resistant Staphylococcus aureus in critically ill adults: a randomized controlled trial
Blackwood, B., Thompson, G., McMullan, R., Stevenson, M., Riley, T. V., Alderdice, F. A., Trinder, T. J., Lavery, G. G. & McAuley, D. F., May 2013, In: Journal of Antimicrobial Chemotherapy. 68, 5, p. 1193-1199Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
2012
Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol
Dark, P., Wilson, C., Blackwood, B., McAuley, D. F., Perkins, G. D., McMullan, R., Gates, S. & Warhurst, G., 12 Jan 2012, (Early online date) In: BMJ Open. 2, 1, 1 p., e000392.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)185 Downloads (Pure) -
2011
Ciprofloxacin use and susceptibility of Gram-negative organisms to quinolone and non-quinolone antibiotics
Troughton, J. A., Millar, G., Smyth, E. T. M., Doherty, L. & McMullan, R., Sept 2011, In: Journal of Antimicrobial Chemotherapy. 66, 9, p. 2152-8 7 p., dkr264.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Long-term gastrointestinal outcomes after Streptococcus bovis bacteraemia
McKenna, A. J., O'Donnell, M. E., McMullan, R. & Irwin, T., Nov 2011, In: International Journal of Clinical Practice. 65, 11, p. 1203-5 3 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
2010
Prior colonisation with Candida species fails to guide empirical therapy for candidaemia in critically ill adults
Troughton, J. A., Browne, G., McAuley, D. F., Walker, M. J., Patterson, C. C. & McMullan, R., 01 Nov 2010, In: Journal of Infection. 61, 5, p. 403-409 7 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus)266 Downloads (Pure) -
The impact of a PCR assay for candidemia on antifungal drug prescribing in critical care: an interrupted time series pilot study.
McMullan, R., Metwally, L., Troughton, J. A., Hedderwick, S., Coyle, P., McAuley, D., McCloskey, B. V., O'Hare, S., Webb, C. H. & Hay, R., Jul 2010, In: Journal of Infection. 61(1), 1, p. 81-85 5 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
2008
A prospective clinical trial of a real-time polymerase chain reaction assay for the diagnosis of candidemia in nonneutropenic, critically ill adults
McMullan, R., Metwally, L., Coyle, P., O'Neill, H., McCloskey, B., Hedderwick, S., Patterson, C., Thompson, G., Webb, C. & Hay, R., 15 Mar 2008, In: Clinical Infectious Diseases. 46, 6, p. 890-896 7 p.Research output: Contribution to journal › Article › peer-review
121 Citations (Scopus)1 Downloads (Pure) -
A randomized controlled trial of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin-resistant Staphylococcus aureus (MRSA) in critically ill adults: research protocol
Thompson, G., Blackwood, B., McMullan, R., Alderdice, F. A., Trinder, T. J., Lavery, G. G. & McAuley, D. F., 28 Nov 2008, In: BMC Infectious Diseases. 8, 161, p. 161-170 9 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Comparison of serum and whole-blood specimens for the detection of Candida DNA in critically ill, non-neutropenic patients
Metwally, L., Fairley, D. J., Coyle, P. V., Hay, R. J., Hedderwick, S., McCloskey, B., O'Neill, H. J., Webb, C. H. & McMullan, R., Oct 2008, In: Journal of Medical Microbiology. 57, Pt 10, p. 1269-72 4 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
Evaluation of the VITEK 2 AST N-054 test card for the detection of extended-spectrum beta-lactamase production in Escherichia coli with CTX-M phenotypes
Donaldson, H., McCalmont, M., Livermore, D. M., Rooney, P. J., Ong, G., McHenry, E., Campbell, R. & McMullan, R., Nov 2008, In: Journal of Antimicrobial Chemotherapy. 62, 5, p. 1015-7 3 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Improving molecular detection of Candida DNA in whole blood: comparison of seven fungal DNA extraction protocols using real-time PCR
Metwally, L., Fairley, D. J., Coyle, P. V., Hay, R. J., Hedderwick, S., McCloskey, B., O'Neill, H. J., Webb, C. H., Elbaz, W. & McMullan, R., Mar 2008, In: Journal of Medical Microbiology. 57, Pt 3, p. 296-303 8 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
2007
Clinico-epidemiological features of infections caused by CTX-M type extended spectrum beta lactamase-producing Escherichia coli in hospitalised patients
McMullan, R., Loughrey, A. C., McCalmont, M. & Rooney, P. J., Jan 2007, In: Journal of Infection. 54, 1, p. 46-52 7 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Food-poisoning and commercial air travel
McMullan, R., Edwards, P. J., Kelly, M. J., Millar, B. C., Rooney, P. J. & Moore, J. E., Sept 2007, In: Travel medicine and infectious disease. 5, 5, p. 276-86 11 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
Rapid differentiation between fluconazole-sensitive and -resistant species of Candida directly from positive blood-culture bottles by real-time PCR
Metwally, L., Hogg, G., Coyle, P. V., O'Neill, H. J., Ong, G. M., Thompson, G., Webb, C. H., McMullan, R., Hay, R. J., Hedderwick, S. & McCloskey, B., 01 Jul 2007, In: Journal of Medical Microbiology. 56, 7, p. 964-970 7 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
Trends in candidemia and antifungal susceptibility in a university hospital in Northern Ireland 2001-2006
Metwally, L., Walker, M. J., Coyle, P. V., O'Neill, H. J., Webb, C. H., McMullan, R., Hay, R. J., Hedderwick, S. & McCloskey, B. V., 01 Aug 2007, In: Journal of Infection. 55, 2, p. 174-178 5 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
2006
Diagnosis and treatment of endogenous fungal endophthalmitis
Williams, M., McMullan, R., Hedderwick, S., Mulholland, D. A. & Best, R. M., 01 Feb 2006, In: Ophthalmologica: International Journal of Ophthalmology. 220, 2, p. 134-136 3 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
The epidemiology of peritonsillar abscess disease in Northern Ireland
Hanna, B. C., McMullan, R., Gallagher, G. & Hedderwick, S., Apr 2006, In: Journal of Infection. 52, 4, p. 247-53 7 p.Research output: Contribution to journal › Article › peer-review
56 Citations (Scopus) -
Trichosporon Asahii. Blood-stream infection in a non-cancer patient receiving combination antifungal therapy
O'Gorman, C., McMullan, R., Webb, C. H. & Bedi, A., 01 Sept 2006, In: The Ulster Medical Journal. 75, 3, p. 226-227 2 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
2005
Frequency and distribution of group I intron genotypes of Candida albicans colonising critically ill patients
Millar, B. C., Xu, J., Moore, J. E., McMullan, R., Walker, M. J. & Hedderwick, S., 01 Jan 2005, In: British Journal of Biomedical Science. 62, 1, p. 24-27 4 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus)