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Ryan Donnelly graduated with a BSc (1st Class) in Pharmacy from Queen's University Belfast in 1999. Following a year of Pre-Registration training spent in Community Pharmacy, he returned to the School of Pharmacy to undertake a PhD in Pharmaceutics. He graduated in 2003 and, after a short period of post-doctoral research, was appointed to a Lectureship in Pharmaceutics in January 2004. He was promoted to Senior Lecturer in 2009, Reader in 2011 and, in 2013, to a Chair in Pharmaceutical Technology.
Professor Donnelly's research is centred on design and physicochemical characterisation of advanced polymeric drug delivery systems for transdermal and topical drug delivery, with a strong emphasis on improving therapeutic outcomes for patients. His bioadhesive patch design was used in successful photodynamic therapy of over 100 patients with neoplastic and dysplastic gynaecological conditions and the patent subsequently out-licensed.
Currently, Professor Donnelly's research is focussed on novel polymeric microneedle arrays for transdermal administration of "difficult-to-deliver" drugs and intradermal delivery of vaccines and photosensitisers. His work is funded by BBSRC, EPSRC, MRC, The Wellcome Trust, The Royal Society and the pharmaceutical and medical devices industries.
He has authored over 600 peer-reviewed publications, including several granted patents, 5 textbooks and approximately 160 full papers. He has been an invited speaker at numerous national and international conferences. Professor Donnelly is the Editor-in-Chief of Recent Patents on Drug Delivery & Formulation and a member of the Editorial Advisory Boards of Micromachines, Pharmaceutical Technology Europe, Expert Review of Medical Devices and Journal of Pharmacy & Bioallied Sciences and is a Visiting Scientist at the Norwegian Institute for Cancer Research, where he is an Associate Member of the Radiation Biology Group. His work has attracted numerous awards, including the Controlled Release Society Young Investigator Award in 2016, BBSRC Innovator of the Year in 2013, the GSK Emerging Scientist Award in 2012 and the Royal Pharmaceutical Society Science Award in 2011.
Click on the links below to watch videos about Professor Donnelly's research:
https://www.youtube.com/watch?v=0IVz_Lfz-2k
http://www.youtube.com/watch?v=cNwVvcXLiWc
http://www.bbc.co.uk/programmes/p048hs6x
http://www.bbc.co.uk/news/health-30333844
https://vimeo.com/232688480
http://www.youtube.com/watch?v=IJmQiS0qXCI
https://www.youtube.com/watch?v=OgyyyKv4Ouk&list=UUmW-7ioJrpEbEUbsbNXlC1A
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Projects
R6617PMY: Ocular Research By Integrated Training And Learning
Singh, T. R. R., Donnelly, R. & Larrañeta, E.
03/05/2019 → …
Project: Research
R1040PMY: Nanoengineered microneedle arrays for enhanced delivery of long-acting HIV medicines
27/03/2019 → …
Project: Research
R1105PMY: Industrial scale microneedle design and manufacture and microneedle applicator design
01/08/2011 → 17/12/2019
Project: Research
Research Output
A novel transdermal protein delivery strategy via electrohydrodynamic coating of PLGA microparticles onto microneedles
Angkawinitwong, U., Courtenay, A. J., Rodgers, A., Larraneta, E., McCarthy, H. O., Brocchini, S., Donnelly, R. F. & Williams, G. R., 18 Feb 2020, In : ACS Applied Materials and Interfaces.Research output: Contribution to journal › Article
Cellulose Nanofibers and Other Biopolymers for Biomedical Applications. A Review
Moohan, J., Stewart, S. A., Espinosa, E., Rosal, A., Rodríguez, A., Larrañeta, E., Donnelly, R. F. & Domínguez-Robles, J., Jan 2020, In : Applied Sciences. 10, 1, 25 p., 65.Research output: Contribution to journal › Literature review
Open Access
File
Development of a Biodegradable Subcutaneous Implant for Prolonged Drug Delivery Using 3D Printing
Stewart, S. A., Domínguez-Robles, J., McIlorum, V. J., Mancuso, E., Lamprou, D. A., Donnelly, R. F. & Larrañeta, E., 28 Jan 2020, In : Pharmaceutics. 12, 2, 16 p., 105.Research output: Contribution to journal › Article
Open Access
File
Enhancement in site-specific delivery of carvacrol for potential treatment of infected wounds using infection responsive nanoparticles loaded into dissolving microneedles: A proof of concept study
Mir, M., Permana, A. D., Ahmed, N., Khan, G. M., Rehman, A. U. & Donnelly, R. F., 16 Dec 2020, (Accepted) In : European Journal of Pharmaceutics and Biopharmaceutics. 147, p. 57-68 12 p.Research output: Contribution to journal › Article
Open Access
File
Evaluation of the clinical impact of repeat application of hydrogel-forming microneedle array patches
Al-Kasasbeh, R., Brady, A. J., Courtenay, A. J., Larrañeta, E., McCrudden, M. T. C., O'Kane, D., Liggett, S. & Donnelly, R. F., 26 Feb 2020, In : Drug Delivery and Translational Research.Research output: Contribution to journal › Article
Open Access
File
Activities
Science vs. Microbes
Johanne Barry (Invited speaker), Sara Cordeiro (Chair), Emma McAlister (Organiser), Ryan Donnelly (Invited speaker), Brendan Gilmore (Invited speaker), Aaron Brady (Invited speaker)20 Feb 2020
Activity: Talk or presentation types › Public lecture/debate/seminar
Controlled Release Society
Thakur Raghu Raj Singh (Participant), Samer Adwan (Participant), Ryan Donnelly (Participant)21 Jul 2018 → 24 Jul 2018
Activity: Participating in or organising an event types › Participation in conference
15TH EUROPEAN SYMPOSIUM ON CONTROLLED DRUG DELIVERY
Thakur Raghu Raj Singh (Participant), Ryan Donnelly (Participant), Samer Adwan (Participant)11 Apr 2018 → 13 Apr 2018
Activity: Participating in or organising an event types › Participation in conference
Fractional Er:YAG Laser as a Novel Method for Enhancing Ocular Drug Permeation
Samer Adwan (Speaker), Thakur Raghu Raj Singh (Advisor), Ryan Donnelly (Advisor)2017 → …
Activity: Talk or presentation types › Oral presentation