Projects per year
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Interests
Ryan Donnelly graduated with a BSc (1st Class) in Pharmacy from Queen's University Belfast in 1999. Following a year of Pre-Registration training spent in Community Pharmacy, he returned to the School of Pharmacy to undertake a PhD in Pharmaceutics. He graduated in 2003 and, after a short period of post-doctoral research, was appointed to a Lectureship in Pharmaceutics in January 2004. He was promoted to Senior Lecturer in 2009, Reader in 2011 and, in 2013, to a Chair in Pharmaceutical Technology.
Professor Donnelly's research is centred on design and physicochemical characterisation of advanced polymeric drug delivery systems for transdermal and topical drug delivery, with a strong emphasis on improving therapeutic outcomes for patients. His bioadhesive patch design was used in successful photodynamic therapy of over 100 patients with neoplastic and dysplastic gynaecological conditions and the patent subsequently out-licensed.
Currently, Professor Donnelly's research is focussed on novel polymeric microneedle arrays for transdermal administration of "difficult-to-deliver" drugs and intradermal delivery of vaccines and photosensitisers. His work is funded by BBSRC, EPSRC, MRC, The Wellcome Trust, The Royal Society and the pharmaceutical and medical devices industries.
He has authored over 600 peer-reviewed publications, including several granted patents, 6 textbooks and approximately 260 full papers. He has been an invited speaker at numerous national and international conferences. Professor Donnelly is the Europe/Africa Editor of Drug Delivery & Translational Research and a member of the Editorial Advisory Boards of Journal of Controlled Release, Micromachines and Expert Review of Medical Devices and is a Visiting Scientist at the Norwegian Institute for Cancer Research, where he is an Associate Member of the Radiation Biology Group. He is a Board Member of the Academy of Pharmaceutical Sciences and the Communications Chair of the Controlled Release Society. His work has attracted numerous awards, including the Academy of Pharmaceutical Sciences Innovative Science Award in 2020, the Controlled Release Society Young Investigator Award in 2016, BBSRC Innovator of the Year in 2013, the GSK Emerging Scientist Award in 2012 and the Royal Pharmaceutical Society Science Award in 2011.
Click on the links below to watch videos about Professor Donnelly's research:
https://www.youtube.com/watch?v=0IVz_Lfz-2k
http://www.youtube.com/watch?v=cNwVvcXLiWc
http://www.bbc.co.uk/programmes/p048hs6x
http://www.bbc.co.uk/news/health-30333844
https://vimeo.com/232688480
http://www.youtube.com/watch?v=IJmQiS0qXCI
https://www.youtube.com/watch?v=OgyyyKv4Ouk&list=UUmW-7ioJrpEbEUbsbNXlC1A
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Network
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R6617PMY: Ocular Research By Integrated Training And Learning
Singh, T. R. R., Donnelly, R. & Larrañeta, E.
03/05/2019 → …
Project: Research
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R1040PMY: Nanoengineered microneedle arrays for enhanced delivery of long-acting HIV medicines
27/03/2019 → …
Project: Research
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R1105PMY: Industrial scale microneedle design and manufacture and microneedle applicator design
01/08/2011 → …
Project: Research
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R1046PMY: In vitro and vivo safety investigations to support the commercialisation of novel mirroneedle arrays for transdermal drug delivery
Donnelly, R. & Woolfson, D.
01/08/2009 → …
Project: Research
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3D-printed implantable devices with biodegradable rate-controlling membrane for sustained delivery of hydrophobic drugs
Picco, C. J., Domínguez-Robles, J., Utomo, E., Paredes, A. J., Volpe-Zanutto, F., Malinova, D., Donnelly, R. F. & Larrañeta, E., 01 Apr 2022, In: Drug Delivery. 29, 1, p. 1038-1048 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Downloads (Pure) -
3D-printed reservoir-type implants containing poly(lactic acid)/poly(caprolactone) porous membranes for sustained drug delivery
Korelidou, A., Domínguez-Robles, J., Magill, E., Eleftheriadou, M., Cornelius, V. A., Donnelly, R. F., Margariti, A. & Larrañeta, E., 09 Jul 2022, (Early online date) In: Biomaterials Advances. 213024.Research output: Contribution to journal › Article › peer-review
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A New and Sensitive HPLC-UV Method for Rapid and Simultaneous Quantification of Curcumin and D-Panthenol: Application to In Vitro Release Studies of Wound Dressings
Anjani, Q. K., Utomo, E., Domínguez-Robles, J., Detamornrat, U., Donnelly, R. F. & Larrañeta, E., 08 Mar 2022, In: Molecules. 27, 6, 1759.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Downloads (Pure) -
A Novel In Vitro Approach to Investigate the Effect of Food Intake on Release Profile of Valsartan in Solid Dispersion-Floating Gel In-Situ Delivery System
Himawan, A., Djide, N. J. N., Mardikasari, S. A., Utami, R. N., Arjuna, A., Donnelly, R. F. & Permana, A. D., Jan 2022, In: European journal of pharmaceutical sciences. 168, 106057.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Downloads (Pure) -
Beneath the Skin: A Review of Current Trends and Future Prospects of Transdermal Drug Delivery Systems
Alkilani, A. Z., Nasereddin, J., Hamed, R., Nimrawi, S., Hussein, G., Abo-Zour, H. & Donnelly, R. F., Jun 2022, In: Pharmaceutics. 14, 6, 1152.Research output: Contribution to journal › Review article › peer-review
Open AccessFile12 Downloads (Pure)
Datasets
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Dataset for "Enzyme triggered L-α/D-peptide hydrogels as a long-acting injectable delivery platform for HIV/AIDS"
Coulter, S. (Data Collector), Pentlavalli, S. (Data Collector), Cross, E. (Data Collector), An, Y. (Data Collector), Vora, L. (Contributor), Peng, K. (Contributor), McAulay, K. (Contributor), Schweins, R. (Contributor), Donnelly, R. (Contributor), McCarthy, H. (Contributor) & Laverty, G. (Creator), Queen's University Belfast, 11 Jul 2022
DOI: 10.17034/67d0cd6f-5bed-4148-b986-f43975b0392c
Dataset
Prizes
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Best Paper Award of Pharmaceutics Special Issue on 3D Printing of Pharmaceuticals and Drug Delivery Devices
Dominguez Robles, Juan (Recipient), Martin, N. K. (Recipient), Fong, M. L. (Recipient), Stewart, S. (Recipient), Irwin, N. (Recipient), Rial, I. (Recipient), Donnelly, Ryan (Recipient) & Larrañeta, Eneko (Recipient), 2020
Prize: Other distinction
Activities
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Hydrogel-forming microneedles for the long-acting delivery of a model hydrophobic drug.
Yara Naser (Advisor), Ismaiel Tekko (Advisor), Qonita Anjani (Advisor) & Ryan Donnelly (Advisor)
Jul 2021Activity: Talk or presentation types › Invited talk
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International Journal of Pharmaceutics (Journal)
Ryan Donnelly (Guest editor), Dimitrios Lamprou (Guest editor) & Eneko Larrañeta (Guest editor)
22 May 2020 → 31 Mar 2021Activity: Publication peer-review and editorial work types › Editorial activity
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Science vs. Microbes
Johanne Barry (Invited speaker), Sara Cordeiro (Chair), Emma McAlister (Organiser), Ryan Donnelly (Invited speaker), Brendan Gilmore (Invited speaker) & Aaron Brady (Invited speaker)
20 Feb 2020Activity: Talk or presentation types › Public lecture/debate/seminar
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15TH EUROPEAN SYMPOSIUM ON CONTROLLED DRUG DELIVERY
Thakur Raghu Raj Singh (Participant), Ryan Donnelly (Participant) & Samer Adwan (Participant)
11 Apr 2018 → 13 Apr 2018Activity: Participating in or organising an event types › Participation in conference
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Controlled Release Society
Thakur Raghu Raj Singh (Participant), Samer Adwan (Participant) & Ryan Donnelly (Participant)
21 Jul 2018 → 24 Jul 2018Activity: Participating in or organising an event types › Participation in conference