Personal profile
Interests
Ryan Donnelly graduated with a BSc (1st Class) in Pharmacy from Queen's University Belfast in 1999. Following a year of Pre-Registration training spent in Community Pharmacy, he returned to the School of Pharmacy to undertake a PhD in Pharmaceutics. He graduated in 2003 and, after a short period of post-doctoral research, was appointed to a Lectureship in Pharmaceutics in January 2004. He was promoted to Senior Lecturer in 2009, Reader in 2011 and, in 2013, to a Chair in Pharmaceutical Technology.
Professor Donnelly's research is centred on design and physicochemical characterisation of advanced polymeric drug delivery systems for transdermal and topical drug delivery, with a strong emphasis on improving therapeutic outcomes for patients. His bioadhesive patch design was used in successful photodynamic therapy of over 100 patients with neoplastic and dysplastic gynaecological conditions and the patent subsequently out-licensed.
Currently, Professor Donnelly's research is focussed on novel polymeric microneedle arrays for transdermal administration of "difficult-to-deliver" drugs and intradermal delivery of vaccines and photosensitisers. His work is funded by BBSRC, EPSRC, MRC, The Wellcome Trust, The Royal Society and the pharmaceutical and medical devices industries.
He has authored over 600 peer-reviewed publications, including several granted patents, 6 textbooks and approximately 260 full papers. He has been an invited speaker at numerous national and international conferences. Professor Donnelly is the Europe/Africa Editor of Drug Delivery & Translational Research and a member of the Editorial Advisory Boards of Journal of Controlled Release, Micromachines and Expert Review of Medical Devices and is a Visiting Scientist at the Norwegian Institute for Cancer Research, where he is an Associate Member of the Radiation Biology Group. He is a Board Member of the Academy of Pharmaceutical Sciences and the Communications Chair of the Controlled Release Society. His work has attracted numerous awards, including the Academy of Pharmaceutical Sciences Innovative Science Award in 2020, the Controlled Release Society Young Investigator Award in 2016, BBSRC Innovator of the Year in 2013, the GSK Emerging Scientist Award in 2012 and the Royal Pharmaceutical Society Science Award in 2011.
Click on the links below to watch videos about Professor Donnelly's research:
https://www.youtube.com/watch?v=0IVz_Lfz-2k
http://www.youtube.com/watch?v=cNwVvcXLiWc
http://www.bbc.co.uk/programmes/p048hs6x
http://www.bbc.co.uk/news/health-30333844
https://vimeo.com/232688480
http://www.youtube.com/watch?v=IJmQiS0qXCI
https://www.youtube.com/watch?v=OgyyyKv4Ouk&list=UUmW-7ioJrpEbEUbsbNXlC1A
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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R6617PMY: Ocular Research By Integrated Training And Learning
Singh, T. R. R. (PI), Donnelly, R. (CoI) & Larrañeta, E. (CoI)
03/05/2019 → …
Project: Research
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R1040PMY: Nanoengineered microneedle arrays for enhanced delivery of long-acting HIV medicines
Donnelly, R. (PI) & Larrañeta, E. (CoI)
27/03/2019 → 30/09/2023
Project: Research
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R2435PMY: 3D bioprinting for enhanced biosensing, regenerative medicine and pharmaceutical manufacture
Donnelly, R. (PI), Andrews, G. (CoI), Bell, S. (CoI), Boyd, P. (CoI), Buchanan, F. (CoI), Cao, C. (CoI), Gilmore, B. (CoI), Larrañeta, E. (CoI), Longley, D. (CoI), O'Kane, C. (CoI), Scott, C. (CoI) & Singh, T. R. R. (CoI)
12/09/2017 → 27/03/2023
Project: Research
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R1530PMY: Delivery of novel peptide drugs for the purpose of modulating immune responses in disease and vaccines
Donnelly, R. (PI), Kissenpfennig, A. (CoI), Scott, C. (CoI) & Woolfson, D. (CoI)
15/05/2015 → 31/08/2016
Project: Research
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R1442PMY: MRC CiC 2013
Donnelly, R. (PI), Kissenpfennig, A. (CoI) & Woolfson, D. (CoI)
01/07/2014 → 31/08/2015
Project: Research
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Assessment of leachables and extractables in “super-swelling” hydrogel-forming microarray patches
Anjani, Q. K., McKenna, P. E., Larrañeta, E., Manesiotis, P., Luo, Y., Adhami, M., Volpe-Zanutto, F., Orr, G., Roussel, S. & Donnelly, R. F., Jan 2026, In: Drug Delivery and Translational Research. 16, 1, p. 397-409 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)113 Downloads (Pure) -
Assessment of microneedle array insertion into skin using Raman spectroscopic techniques
Jamaledin, R., Zarmpi, P., Alambiaga-Caravaca, A. M., Tyagi, V., Anjani, Q. K., Larrañeta, E., Donnelly, R. F., Belsey, N. A., Guy, R. H. & Delgado-Charro, M. B., 13 Jan 2026, (Early online date) In: Drug Delivery and Translational Research. 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Correction to: Rapidly dissolving polymeric microneedles for minimally invasive intraocular drug delivery
Thakur, R. R. S., Tekko, I. A., Al-Shammari, F., Ali, A. A., McCarthy, H. & Donnelly, R. F., 20 Feb 2026, (Early online date) In: Drug Delivery and Translational Research.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Corrigendum to "Dissolvable microarray patches of levodopa and carbidopa for Parkinson's disease management" [Eur. J. Pharm. Biopharm. 199 (2024) 114304]
Anjani, Q. K., Moreno-Castellanos, N., Li, Y., Sabri, A. H. B. & Donnelly, R. F., 01 Jan 2026, In: European Journal of Pharmaceutics and Biopharmaceutics. 218, 2 p., 114928.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Corrigendum to "Enhancement in site-specific delivery of carvacrol for potential treatment of infected wounds using infection responsive nanoparticles loaded into dissolving microneedles: a proof of concept study." [Eur. J. Pharm. Biopharm. 147 (2020) 57-68]
Mir, M., Permana, A. D., Ahmed, N., Khan, G. M., Rehman, A. U. & Donnelly, R. F., 01 Jan 2026, In: European Journal of Pharmaceutics and Biopharmaceutics. 218, 2 p., 114927.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Dataset for "Enzyme triggered L-α/D-peptide hydrogels as a long-acting injectable delivery platform for HIV/AIDS"
Coulter, S. (Data Collector), Pentlavalli, S. (Data Collector), Cross, E. (Data Collector), An, Y. (Data Collector), Vora, L. (Contributor), Peng, K. (Contributor), McAulay, K. (Contributor), Schweins, R. (Contributor), Donnelly, R. (Contributor), McCarthy, H. (Contributor) & Laverty, G. (Creator), Queen's University Belfast, 11 Jul 2022
DOI: 10.17034/67d0cd6f-5bed-4148-b986-f43975b0392c
Dataset
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Dataset for "Polymeric microarray patches for transdermal delivery of amodiaquine and artesunate: A novel strategy against Plasmodium falciparum"
Anjani, Q. K. (Creator), ZANUTTO, F. V. (Contributor), Miatmoko, A. (Contributor), Moreno-Castellanos, N. (Contributor), Novais, J. T. (Contributor), Gaitán, X. A. (Contributor), Hariawan, B. S. (Contributor), Cahyani, D. M. (Contributor), Octavia, R. T. (Contributor), Mubarok, A. S. (Contributor), Setyaningsih, W. A. W. (Contributor), Johnston, C. (Contributor), Bargieri, D. Y. (Contributor) & Donnelly, R. (Creator), Queen's University Belfast, 06 Nov 2025
DOI: 10.17034/2dd2723f-ccd5-4e56-bc2d-c405323a25df
Dataset
Prizes
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2022 AAPS Pharmaceutical Research Meritorious Manuscript Award
Vora, L. (Recipient) & Donnelly, R. (Recipient), 2022
Prize: Prize (including medals and awards)
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Best Paper Award of Pharmaceutics Special Issue on 3D Printing of Pharmaceuticals and Drug Delivery Devices
Dominguez Robles, J. (Recipient), Martin, N. K. (Recipient), Fong, M. L. (Recipient), Stewart, S. (Recipient), Irwin, N. (Recipient), Rial, I. (Recipient), Donnelly, R. (Recipient) & Larrañeta, E. (Recipient), 2020
Prize: Other distinction
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Most Cited Paper Award 2023
Vora, L. (Recipient), Paredes, A. (Recipient), Donnelly, R. (Recipient), VOLPE ZANUTTO, F. (Recipient), Singh, T. R. R. (Recipient) & Mishra, D. (Recipient), Mar 2024
Prize: Prize (including medals and awards)
Activities
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Hydrogel-forming microneedles for the long-acting delivery of a model hydrophobic drug.
Naser, Y. (Advisor), Tekko, I. (Advisor), Anjani, Q. (Advisor) & Donnelly, R. (Advisor)
Jul 2021Activity: Talk or presentation types › Invited talk
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International Journal of Pharmaceutics (Journal)
Donnelly, R. (Guest editor), Lamprou, D. (Guest editor) & Larrañeta, E. (Guest editor)
22 May 2020 → 31 Mar 2021Activity: Publication peer-review and editorial work types › Editorial activity
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Science vs. Microbes
Barry, J. (Invited speaker), Cordeiro, S. (Chair), McAlister, E. (Organiser), Donnelly, R. (Invited speaker), Gilmore, B. (Invited speaker) & Brady, A. (Invited speaker)
20 Feb 2020Activity: Talk or presentation types › Public lecture/debate/seminar
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Controlled Release Society
Singh, T. R. R. (Participant), Adwan, S. (Participant) & Donnelly, R. (Participant)
21 Jul 2018 → 24 Jul 2018Activity: Participating in or organising an event types › Participation in conference
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15TH EUROPEAN SYMPOSIUM ON CONTROLLED DRUG DELIVERY
Singh, T. R. R. (Participant), Donnelly, R. (Participant) & Adwan, S. (Participant)
11 Apr 2018 → 13 Apr 2018Activity: Participating in or organising an event types › Participation in conference
Press/Media
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Researchers develop new 3D ring technology which could offer solution for HIV management
09/03/2023
1 item of Media coverage
Press/Media: Research