Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Sandra Van Schaeybroeck is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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R6416CNR: Phase 1B/II study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor PF-02341066 in KRASMT and KRASWT (with aberrant c-MET) Colorectal Cancer Patients
Van Schaeybroeck, S. (PI), Johnston, P. (CoI), Kennedy, R. (CoI), Lawler, M. (CoI), Longley, D. (CoI), Salto-Tellez, M. (CoI) & Wilson, R. (CoI)
01/08/2013 → …
Project: Research
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R1938CNR: Development of biomarkers for inhibitors of GRP78, the master regulator of the unfolded protein response, for poor prognostic colorectal cancer subgroups.
Van Schaeybroeck, S. (PI) & Kennedy, R. (CoI)
06/09/2018 → 30/09/2020
Project: Research
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R1290CNR: Development of EGFR Targeted Camptothecin-Loaded Nanoparticles for Targeting Kras Wild-Type Colorectal Cancer
Longley, D. (PI), Scott, C. (CoI) & Van Schaeybroeck, S. (CoI)
01/08/2012 → 30/09/2014
Project: Research
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R6383CNR: Apoptosis Modelling for Treatment Decisions in Colorectal Cancer
Van Schaeybroeck, S. (PI), Johnston, P. (CoI) & Longley, D. (CoI)
01/08/2012 → 31/10/2014
Project: Research
Research output
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Immune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma: a translational analysis of the DEBIOC clinical trial
Scanlon, E., Lavery, A., Albraikat, M., Stevenson, L., Kennedy, C., Byrne, R., Walker, A., Mullan-Young, B., McManus, D. T., Virdee, P. S., Elhussein, L., Turbitt, J., Collinson, D., Miedzybrodzka, Z., Van Schaeybroeck, S., McQuaid, S., James, J. A., Craig, S. G., Blayney, J. K. & Petty, R. D. & 6 others, , Nov 2024, In: ESMO Open. 9, 11, 14 p., 103930.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Ruthenium drug BOLD-100 regulates BRAFMT colorectal cancer cell apoptosis through AhR/ROS/ATR signaling axis modulation
Griffin, D., Carson, R., Moss, D., Sessler, T., Lavin, D., Tiwari, V., Karelia, S., Kennedy, R., Savage, K. I., McDade, S., Carie, A., Pankovich, J., Bazett, M. & Van Schaeybroeck, S., 04 Sept 2024, (Early online date) In: Molecular Cancer Research. 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Bcl-xL is a key mediator of apoptosis following KRASG12C inhibition in KRASG12C-mutant colorectal cancer
Khawaja, H., Briggs, R., Latimer, C. H., Rassel, M., Griffin, D., Hanson, L., Bardelli, A., Di Nicolantonio, F., McDade, S. S., Scott, C. J., Lambe, S., Maurya, M., Lindner, A. U., Prehn, J. H. M., Sousa, J., Winnington, C., LaBonte, M. J., Ross, S. & Van Schaeybroeck, S., 01 Jan 2023, In: Molecular Cancer Therapeutics. 22, 1, p. 135–149 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)76 Downloads (Pure) -
USP17 is required for peripheral trafficking of lysosomes
Lin, J., McCann, A., Sereesongsaeng, N., Burden, J., Alsa'd, A. A. M., Burden, R., Micu, I., Williams, R., Van Schaeybroeck, S., Evergren, E., Mullan, P., Scott, C. & Burrows, J., 26 Jan 2022, In: EMBO Reports.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)264 Downloads (Pure) -
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution
Lindner, A. U., Salvucci, M., McDonough, E., Cho, S., Stachtea, X., O'Connell, E. P., Corwin, A. D., Santamaria-Pang, A., Carberry, S., Fichtner, M., Van Schaeybroeck, S., Laurent-Puig, P., Burke, J. P., McNamara, D. A., Lawler, M., Sood, A., Graf, J. F., Rehm, M., Dunne, P. D. & Longley, D. B. & 2 others, , 09 Nov 2021, (Early online date) In: Cell death and differentiation.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)92 Downloads (Pure)
Activities
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Targeting poor prognostic molecular subtypes in colorectal cancer
Van Schaeybroeck, S. (Keynote speaker)
17 May 2019Activity: Talk or presentation types › Invited talk
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Daniel Hochhauser
Van Schaeybroeck, S. (Host)
09 May 2019Activity: Hosting a visitor types › Hosting an academic visitor
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COLOSSUS CRC PPI event at RCSI
Van Schaeybroeck, S. (Keynote speaker)
30 Apr 2019Activity: Talk or presentation types › Invited talk
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Molecular Cancer Therapeutics (Journal)
Van Schaeybroeck, S. (Peer reviewer)
25 Sept 2018Activity: Publication peer-review and editorial work types › Publication peer-review
Press/Media
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Queen’s researchers discover ground-breaking process which destroys bowel cancer cells
Van Schaeybroeck, S., Johnston, P. G., Johnston, P. G. & Johnston, P. G.
06/09/2018
8 items of Media coverage
Press/Media: Research
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RESEARCHERS FIND KEY TO DRUG RESISTANT BOWEL CANCER
08/11/2016
2 items of Media coverage
Press/Media: Research
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Queen’s leads €6million European study to combat bowel cancer
14/12/2013
1 item of Media coverage
Press/Media: Research