• Room 03.010 - CCRCB

    United Kingdom

Accepting PhD Students

PhD projects

Dr. Van Schaeybroeck is interested in PhD applications from candidates with a basic science or clinical background in the fields of; - Laboratory based investigations into molecular mechanisms including altered pro-survival signaling pathways in RASMT and BRAFMT CRC - Discovery of novel resistance mechanisms to therapy mechanisms in RASMT and BRAFMT CRC - Innovative biomarker development using samples from RASMT and BRAFMT CRC patients


Research output per year

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Research Output

A Machine Learning Platform to Optimize the Translation of Personalized Network Models to the Clinic

Salvucci, M., Rahman, A., Resler, A. J., Udupi, G. M., McNamara, D. A., Kay, E. W., Laurent-Puig, P., Longley, D. B., Johnston, P. G., Lawler, M., Wilson, R., Salto-Tellez, M., Van Schaeybroeck, S., Rafferty, M., Gallagher, W. M., Rehm, M. & Prehn, J. H. M., 17 Apr 2019, In : JCO Clinical Cancer Informatics. 17 p.

Research output: Contribution to journalArticle

Open Access
  • 56 Downloads (Pure)

    Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours

    McDaid, W. J., Greene, M. K., Johnston, M. C., Pollheimer, E., Smyth, P., McLaughlin, K., Van Schaeybroeck, S., Straubinger, R. M., Longley, D. B. & Scott, C. J., 18 Oct 2019, In : Nanoscale. 13 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    A phase I dose escalation multi-centre study of crizotinib (MET inhibitor) combined with binimetinib (MEK inhibitor) in patients with advanced solid tumours

    Wilson, R., Dass, P. H., Van Schaeybroeck, S., Elez, E., Quinton, A., Jones, R., Houlden, J., Collins, L., Roberts, C., Love, S., Lawler, M., Di Nicolantonio, F., Grayson, M., Bardelli, A., Laurent=puig, P., Maughan, T., Tabernero, J., Peeters, M., Middleton, M. & Rolfo, C., Nov 2018, In : European Journal of Cancer. 103, Suppl 1, p. e140-e141

    Research output: Contribution to journalMeeting abstract

    Corrigendum: Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges

    Bradley, C. A., Salto-Tellez, M., Laurent-Puig, P., Bardelli, A., Rolfo, C., Tabernero, J., Khawaja, H. A., Lawler, M., Johnston, P. G., Van Schaeybroeck, S. & MErCuRIC consortium, 23 Jan 2018, In : Nature reviews. Clinical oncology. 15, 3, p. 150 1 p.

    Research output: Contribution to journalArticle

  • Targeting the dopamine receptor 2 in BRAF mutant colorectal cancer

    Javadi, A., Forsythe, N., Refaat, A., Weir, J-A., Khawaja, H., Waugh, D., Tarapore, R., Allen, J. E., Johnston, P. & Van Schaeybroeck, S., Jul 2018, In : Cancer Research. 78, Issue 13 Supplement, 1 p., Abstract 3448.

    Research output: Contribution to journalMeeting abstract



    Sandra Van Schaeybroeck (Keynote speaker)

    30 Apr 2019

    Activity: Talk or presentation typesInvited talk

    Internal examiner

    Sandra Van Schaeybroeck (Examiner)


    Activity: Examination typesOther examination

    Daniel Hochhauser

    Sandra Van Schaeybroeck (Host)

    09 May 2019

    Activity: Hosting a visitor typesHosting an academic visitor

    Targeting poor prognostic molecular subtypes in colorectal cancer

    Sandra Van Schaeybroeck (Keynote speaker)

    17 May 2019

    Activity: Talk or presentation typesInvited talk

    Molecular Cancer Therapeutics (Journal)

    Sandra Van Schaeybroeck (Peer reviewer)

    25 Sep 2018

    Activity: Publication peer-review and editorial work typesPublication peer-review

    Press / Media

    Queen’s researchers discover ground-breaking process which destroys bowel cancer cells

    Sandra Van Schaeybroeck, P.G. Johnston, P.G. Johnston & P.G. Johnston


    8 items of Media coverage

    Press/Media: Research


    Interpreting transcriptional signatures and their relevance to disease biology, prognosis and treatment resistance in colorectal cancer

    Author: Hoare, O., Jul 2020

    Supervisor: Lawler, M. (Supervisor), Dunne, P. (Supervisor) & Van Schaeybroeck, S. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy