Research output per year
Research output per year
- 26 results
Search results
-
2022
Defective antifungal immunity in patients with COVID-19
Morton, C. O., Griffiths, J. S., Loeffler, J., Orr, S. & White, P. L., 30 Nov 2022, (Early online date) In: Frontiers in Immunology. 13, 1080822.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
The use of host biomarkers for the management of invasive fungal disease
Griffiths, J. S., Orr, S. J., Morton, C. O., Loeffler, J. & White, P. L., 16 Dec 2022, In: Journal of Fungi. 8, 12, 16 p., 1307.Research output: Contribution to journal › Review article › peer-review
Open AccessFile45 Downloads (Pure) -
2021
A Human Dectin-2 Deficiency Associated With Invasive Aspergillosis
Griffiths, J. S., White, P. L., Czubala, M. A., Simonazzi, E., Bruno, M., Thompson, A., Rizkallah, P. J., Gurney, M., da Fonseca, D. M., Naglik, J. R., Ingram, W., Wilson, K., van de Veerdonk, F. L., Barnes, R., Taylor, P. R. & Orr, S. J., 18 Mar 2021, (Early online date) In: The Journal of Infectious Diseases.Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Downloads (Pure) -
A Novel Strategy to Identify Haematology Patients at High Risk of Developing Aspergillosis
Griffiths, J. S., White, P. L., Thompson, A., da Fonseca, D. M., Pickering, R. J., Ingram, W., Wilson, K., Barnes, R., Taylor, P. R. & Orr, S. J., 16 Dec 2021, (Early online date) In: Frontiers in Immunology. 12, p. 780160Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Downloads (Pure) -
Dependence on Mincle and Dectin-2 Varies With Multiple Candida Species During Systemic Infection
Thompson, A., da Fonseca, D. M., Walker, L., Griffiths, J. S., Taylor, P. R., Gow, N. A. R. & Orr, S. J., 25 Feb 2021, In: Frontiers in Microbiology. 12, p. 633229Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Downloads (Pure) -
2020
Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway
Ipseiz, N., Pickering, R., Rosas, M., Tyrrell, V., Davis, L., Orr, S., Czubala, M., Fathalla, D., Robertson, A., Bryant, C., O'Donnell, V. & taylor, P., 02 Jun 2020, In: The EMBO Journal.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)131 Downloads (Pure) -
2019
Dependence on Dectin-1 Varies With Multiple Candida Species
Thompson, A., Griffiths, J. S., Walker, L., da Fonseca, D. M., Lee, K. K., Taylor, P. R., Gow, N. A. R. & Orr, S. J., 06 Aug 2019, In: Frontiers in Microbiology. 10, 1800.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)30 Downloads (Pure) -
IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine.
McLaren, JE., Clement, M., Marsden, M., Miners, KL., Llewellyn-Lacey, S., Grant, EJ., Rubina, A., Gimeno, B. S., Gostick, E., Stacey, MA., Orr, SJ., Stanton, RJ. & Humphreys, IR., 01 Feb 2019, In: Journal of Immunology. 202, 3, p. 943-955Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)220 Downloads (Pure) -
The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors
Thompson, A., Davies, L., Liao, C-T., da Fonseca, D., Griffiths, J., Andrews, R., Jones, A., Clement, M., Brown, G., Humphreys, I., Taylor, P. & Orr, S., 26 Jun 2019, In: PLoS Pathogens. 15, 6, p. e1007850Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)186 Downloads (Pure) -
2018
Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases.
Griffiths, JS., Thompson, A., Stott, M., Benny, A., Lewis, NA., Taylor, PR., Forton, J., Herrick, S., Orr, SJ. & McGreal, EP., 01 Jun 2018, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32, 6Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)339 Downloads (Pure) -
Emerging IL-12 family cytokines in the fight against fungal infections.
Thompson, A. & Orr, SJ., May 2018, In: Cytokine.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)158 Downloads (Pure) -
Pattern recognition receptors in fungal immunity.
Patin, EC., Thompson, A. & Orr, SJ., 31 Mar 2018, In: Seminars in cell & developmental biology. p. 24-33Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)60 Downloads (Pure) -
2017
Macrophage Inducible C-Type Lectin As a Multifunctional Player in Immunity.
Patin, EC., Orr, SJ. & Schaible, UE., 25 Jul 2017, In: Frontiers in Immunology. 8, 10 p., 861.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)171 Downloads (Pure) -
2016
IL-27 Induced by Select Candida spp. via TLR7/NOD2 Signaling and IFN-β Production Inhibits Fungal Clearance.
Patin, EC., Jones, AV., Thompson, A., Clement, M., Liao, CT., Griffiths, JS., Wallace, LE., Bryant, CE., Lang, R., Rosenstiel, P., Humphreys, IR., Taylor, PR., Jones, GW. & Orr, SJ., 01 Jun 2016, In: Journal of Immunology. 197, 1, p. 208Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)118 Downloads (Pure) -
Mincle-mediated anti-inflammatory IL-10 response counter-regulates IL-12 in vitro.
Patin, EC., Willcocks, S., Orr, S., Ward, TH., Lang, R. & Schaible, UE., 01 Apr 2016, In: Innate Immunity.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)108 Downloads (Pure) -
Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity.
Burg, AR., Quigley, L., Jones, AV., O'Connor, GM., Boelte, K., McVicar, DW. & Orr, SJ., 21 Jun 2016, In: SpringerPlus.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)100 Downloads (Pure) -
2015
International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease.
Bryant, CE., Orr, S., Ferguson, B., Symmons, MF., Boyle, JP. & Monie, TP., 2015, In: Pharmacological Reviews.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
2014
Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.
Cardone, M., Dzutsev, AK., Li, H., Riteau, N., Gerosa, F., Shenderov, K., Winkler-Pickett, R., Provezza, L., Riboldi, E., Leighty, RM., Orr, SJ., Steinhagen, F., Wewers, MD., Sher, A., Anderson, SK., Goldszmid, R., McVicar, DW., Lyakh, L. & Trinchieri, G., 2014, In: PLoS ONE.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
2013
LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells.
Orr, SJ., Burg, AR., Chan, T., Quigley, L., Jones, GW., Ford, JW., Hodge, D., Razzook, C., Sarhan, J., Jones, YL., Whittaker, GC., Boelte, KC., Lyakh, L., Cardone, M., O'Connor, GM., Tan, C., Li, H., Anderson, SK., Jones, SA. & Zhang, W., May 2013, In: PLoS Pathogens.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
2012
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.
Karsten, CM., Pandey, MK., Figge, J., Kilchenstein, R., Taylor, PR., Rosas, M., McDonald, JU., Orr, SJ., Berger, M., Petzold, D., Blanchard, V., Winkler, A., Hess, C., Reid, DM., Majoul, IV., Strait, RT., Harris, NL., Köhl, G., Wex, E. & Ludwig, R., Sep 2012, In: Nature Medicine.Research output: Contribution to journal › Article › peer-review
272 Citations (Scopus) -
2011
LAB/NTAL/Lat2: a force to be reckoned with in all leukocytes?
Orr, SJ. & McVicar, DW., Jan 2011, In: Journal of Leukocyte Biology.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
2010
Implications for gene therapy-limiting expression of IL-2R gamma c delineate differences in signaling thresholds required for lymphocyte development and maintenance.
Orr, SJ., Roessler, S., Quigley, L., Chan, T., Ford, JW., O'Connor, GM. & McVicar, DW., Aug 2010, In: Journal of Immunology.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
The linker for activation of B cells (LAB)/non-T cell activation linker (NTAL) regulates triggering receptor expressed on myeloid cells (TREM)-2 signaling and macrophage inflammatory responses independently of the linker for activation of T cells.
Whittaker, GC., Orr, SJ., Quigley, L., Hughes, L., Francischetti, IM., Zhang, W. & McVicar, DW., Jan 2010, In: Journal of Biological Chemistry.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
2009
In vivo expression of signaling proteins in reconstituted NK cells.
Orr, SJ., Quigley, L. & McVicar, DW., Jan 2009, In: Journal of Immunological Methods.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
2008
Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire.
Whittaker, GC., Burshtyn, DN., Orr, SJ., Quigley, L., Hodge, DL., Pascal, V., Zhang, W. & McVicar, DW., Oct 2008, In: Blood.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles.
Scott, CJ., Marouf, WM., Quinn, DJ., Buick, RJ., Orr, SJ., Donnelly, RF. & McCarron, PA., Jan 2008, In: Pharmaceutical Research.Research output: Contribution to journal › Article › peer-review