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Dive into the research topics where Seyed Mehdi Jafarnejad is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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R2862CNR: Uncovering the mechanism of resistance to RNA-incorporating drugs in cancer
Jafarnejad, S. M. (PI)
10/02/2022 → …
Project: Research
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R1606CNR: A microRNA conundrum: to degrade or keep a translationally repressed target mRNA?
Jafarnejad, S. M. (PI)
20/12/2021 → …
Project: Research
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R1135CNR: Exploiting the cancer epigenome to develop a common cancer vaccine
McDade, S. (PI), Jafarnejad, S. M. (CoI) & Scott, C. (CoI)
10/01/2020 → 30/06/2022
Project: Research
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Dysregulated ribosome quality control in human diseases
McGirr, T., Onar, O. & Jafarnejad, S. M., 01 Mar 2025, In: The FEBS Journal. 292, 5, p. 936-959 24 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile9 Citations (Scopus)128 Downloads (Pure) -
No evidence that human GIGYF2 interacts with GRB10: implications for human disease
Choi, J.-H., Shpilman, I., Mahmood, N., Farhangmehr, S., Braunschweig, U., Cruz, N. G., Luo, J., Ladak, R. J., Pistofidis, A., Ragoussis, J., Schmeing, T. M., Jafarnejad, S. M., Blencowe, B. J. & Sonenberg, N., 17 Sept 2025, In: Life Science Alliance. 8, 9, e202503334.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction
Choi, J.-H., Luo, J., Hesketh, G. G., Guo, S., Pistofidis, A., Ladak, R. J., An, Y., Naeli, P., Alain, T., Schmeing, T. M., Gingras, A.-C., Duchaine, T., Zhang, X., Sonenberg, N. & Jafarnejad, S. M., 19 Jul 2024, In: Science Advances. 10, 29, 18 p., eadl5638.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)77 Downloads (Pure) -
Ribosome quality control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil
Chatterjee, S., Naeli, P., Onar, O., Simms, N., Garzia, A., Hackett, A., Coyle, K., Harris Snell, P., McGirr, T., Sawant, T. N., Dang, K., Stoichkova, Z. V., Azam, Y., Saunders, M. P., Braun, M., Alain, T., Tuschl, T., McDade, S. S., Longley, D. B. & Gkogkas, C. G. & 3 others, , 11 Nov 2024, In: Nucleic Acids Research. 52, 20, p. 12534-12548 15 p., gkae849.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)90 Downloads (Pure) -
The 4EHP-mediated translational repression of cGAS impedes the host immune response against DNA viruses
Ladak, R. J., Choi, J.-H., Luo, J., Chen, O. J., Mahmood, N., He, A. J., Naeli, P., Snell, P. H., Bayani, E., Hoang, H.-D., Alain, T., Teodoro, J. G., Wang, J., Zhang, X., Jafarnejad, S. M. & Sonenberg, N., 19 Nov 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 48, e2413018121.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)14 Downloads (Pure)
Activities
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Biochemical Society (External organisation)
Jafarnejad, S. M. (Advisor)
24 Apr 2021 → 31 Mar 2024Activity: Membership types › Membership of external research organisation
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Queen's University Belfast (Organisational unit)
Jafarnejad, S. M. (Advisor)
30 Mar 2021 → …Activity: Membership types › Membership of board
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Queen's University Belfast (Organisational unit)
Jafarnejad, S. M. (Advisor)
01 Mar 2021 → 04 Jun 2021Activity: Membership types › Membership of public/government advisory/policy group or panel
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UKRI Early Career Researcher Forum (External organisation)
Jafarnejad, S. M. (Advisor)
01 Feb 2021 → …Activity: Membership types › Membership of external research organisation
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University of Lethbridge (External organisation)
Jafarnejad, S. M. (Advisor)
01 Jul 2020 → …Activity: Membership types › Membership of external research organisation