• Room 01.065 - Pharmacy & MCI

    United Kingdom

Accepting PhD Students

PhD projects

Open to PhD applications in the field of multi-component pharmaceutical materials (including pharmaceutical cocrystals), mechanochemical synthesis, enabling formulation strategies and medical device preparation via hot-melt extrusion.

20092020

Research output per year

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Personal profile

Research Interests

Dr Shu Li's research interests cover the development of novel pharmaceutical dosage forms via innovative manufacturing. Shu specialises particularly in the use of continuous manufacturing techniques, such as hot-melt extrusion, multilayer co-extrusion to enhance the bioavailability of poorly absorbed drugs in order to increase their clinical efficacy when administered orally. Formulation strategies familiar to Dr Li include the design and preparation of amorphous solid dispersions and novel multi-component pharmaceutical materials (such as pharmaceutical cocrystals). She is also interested in extending her field of research to enabling formulations with customisable platform designs, such as flexible-dose combination products, for stratefied treatment and precision medicine. This includes understanding and determination of multi-component behaviour and interactions as well as understanding and predicting the influences such inter-species network may exert on the bioavailability and efficacy of the final dosage forms. To achieve high level of comprehension, a number of analytical techniques are routinely used including thermal analysis (DSC, TGA, DMA), vibrational spectroscopy, X-ray diffraction, thermo and polarised-light microscopy, High Performance Liquid Chromatography, Gas Chromatography, vapour sorption, Nuclear Magnetic Resonance spectroscopy and theoretical modelling. 

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Projects

Research Output

  • 2 Citations (Scopus)

    Co-extruded Fixed Dose Combination Products with Enabled Properties for the Treatment of Cardiovascular Diseases

    Almajaan, A., Li, S., Gilvary, G. C., Senta Loys, Z., Tian, Y., Kelleher, J., Healy, A-M., Jones, D. & Andrews, G., 03 Apr 2019.

    Research output: Contribution to conferencePaper

    Open Access
  • Activities

    International Journal of Pharmaceutics (Journal)

    Shu Li (Peer reviewer)

    2020 → …

    Activity: Publication peer-review and editorial work typesPublication peer-review

    Lead for CQC Exchange Programme

    Nicola Irwin (Organiser), & Shu Li (Organiser)

    13 Jan 202019 Feb 2020

    Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

    Therapeutic Delivery (Journal)

    Shu Li (Editorial board member)

    14 Jan 2020 → …

    Activity: Publication peer-review and editorial work typesEditorial activity

    Mechanochemical Synthesis of a Multicomponent Complex Containing Albendazole and Maleic Acid for Improved Physiochemical Propertie

    Alice Culkin (Presenter), , Gavin Andrews (Advisor), & Shu Li (Advisor)

    17 Apr 201918 Apr 2019

    Activity: Talk or presentation typesOral presentation

    Journal of Drug Delivery Science and Technology (Journal)

    Shu Li (Peer reviewer)

    2019 → …

    Activity: Publication peer-review and editorial work typesPublication peer-review