Projects per year
Personal profile
Research Interests
Dr Shu Li's research interests cover the development of novel pharmaceutical dosage forms via innovative manufacturing. Shu specialises particularly in the use of continuous manufacturing techniques, such as hot-melt extrusion, multilayer co-extrusion to enhance the bioavailability of poorly absorbed drugs in order to increase their clinical efficacy when administered orally. Formulation strategies familiar to Dr Li include the design and preparation of amorphous solid dispersions and novel multi-component pharmaceutical materials (such as pharmaceutical cocrystals). She is also interested in extending her field of research to enabling formulations with customisable platform designs, such as flexible-dose combination products, for stratefied treatment and precision medicine. This includes understanding and determination of multi-component behaviour and interactions as well as understanding and predicting the influences such inter-species network may exert on the bioavailability and efficacy of the final dosage forms. To achieve high level of comprehension, a number of analytical techniques are routinely used including thermal analysis (DSC, TGA, DMA), vibrational spectroscopy, X-ray diffraction, thermo and polarised-light microscopy, High Performance Liquid Chromatography, Gas Chromatography, vapour sorption, Nuclear Magnetic Resonance spectroscopy and theoretical modelling.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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S2412PMY: KTP/Devenish Nutrition Ltd
Andrews, G. (CoI), Jones, D. (CoI), Li, S. (CoI) & Tian, J. (CoI)
01/05/2017 → …
Project: ktp
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Hot melt extruded amorphous solid dispersions containing lumefantrine and Soluplus
Li, S., Zhang, Z., Gu, W., Gallas, M., Jones, D., Boulet, P., Johnson, L. M., de Margerie, V. & Andrews, G. P., 08 Sept 2024, (Early online date) In: International Journal of Pharmaceutics. 124676.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure) -
In situ eutectic formation in a polymeric matrix via hot-melt reactive extrusion and the use of partial least squares regression modeling for reaction yield determination
Andrews, G. P., Culkin, A., Jones, D. S. & Li, S., 13 Aug 2024, (Early online date) In: Molecular Pharmaceutics. 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
Spectroscopic and thermal characterisation of interpenetrating hydrogel networks (IHNs) based on polymethacrylates and Pluronics, and their physicochemical stability under aqueous conditions
Jones, D. S., Westwood, M., Li, S. & Andrews, G. P., 01 Oct 2024, In: Polymers. 16, 19, 19 p., 2796.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Towards a greater understanding of the deep eutectic phenomenon through examination of the lidocaine-NSAID therapeutic deep eutectic systems
Li, S., Abdelquader, M. M., Andrews, G. P. & Jones, D. S., Jul 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 200, 114329.Research output: Contribution to journal › Article › peer-review
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A new mathematical model derived from transient (creep) analysis to estimate the vaginal retention of semi-solid dosage forms
Jones, D. S., Yu, T., Li, S., Pick, L. & Andrews, G. P., 05 Feb 2023, In: International Journal of Pharmaceutics. 632, 13 p., 122521.Research output: Contribution to journal › Article › peer-review
Activities
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Therapeutic Delivery (Journal)
Li, S. (Editorial board member)
14 Jan 2020 → …Activity: Publication peer-review and editorial work types › Editorial activity
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Lead for CQC Exchange Programme
Irwin, N. (Organiser) & Li, S. (Organiser)
13 Jan 2020 → 19 Feb 2020Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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International Journal of Pharmaceutics (Journal)
Li, S. (Peer reviewer)
2020 → …Activity: Publication peer-review and editorial work types › Publication peer-review
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Recommendation Board for Candidate Nomination for the Chinese Government Award for Outstanding Self-financed Students Abroad.
Li, S. (Board member)
19 Sept 2019Activity: Other activity types › Other
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QUB Open Day
Li, S. (Host)
05 Sept 2019Activity: Other activity types › Hosting a school group or open day