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Simon McDade

Dr

 https://orcid.org/0000-0002-3024-4773

  • Room 01.004 - CCRCB

    United Kingdom

Accepting PhD Students

PhD projects

Dr McDade functional genomics (FGG) lab, utilises a range of genomic technologies (RNA-seq, ChIP-seq, CRISPR screen) and integrative data analysis tools to identify novel treatment strategies to improve treatment of cancer patients outcomes. The labs field of interest include: - Transcription factor dysfunction in cancer - Epigenetic lab and data analysis tool development - Colorectal, Prostate and Squamous cancer - Data analysis and Shiny app development We are open to wide ranging lab and data analysis projects from those with a background biology, genomics, data analysis and computational backgrounds. Previous research experience is desirable although not essential

20052020

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Research Statement

The research interests of my lab are in utilising integrative genomic strategies to define genome wide targets, mechanism of action and consequences of deregualtion of transcription factors in cancer with a particular emphasis on the p53 family.  Our ultimate goal is to identify genes or processes altered as a consequence of mutation or de-regulation which could be exploited for diagnostic or therapeutic application. 

 

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  • 44 Article
  • 1 Chapter (peer-reviewed)
  • 1 Meeting abstract
  • 1 Other contribution
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