Projects per year
Personal profile
Research Statement
The research interests of my lab are in utilising integrative genomic strategies to define genome wide targets, mechanism of action and consequences of deregualtion of transcription factors in cancer with a particular emphasis on the p53 family. Our ultimate goal is to identify genes or processes altered as a consequence of mutation or de-regulation which could be exploited for diagnostic or therapeutic application.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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R6840CNR: ONEHEALTH - Artificial Intelligence for Human, Animal, and Environmental
Lawler, M. (PI), Devereux, B. (CoI), Hardiman, G. (CoI), McCabe, C. (CoI), McDade, S. (CoI), Miller, P. (CoI), O'Connell, N. (CoI), Overton, I. (CoI), Scollan, N. (CoI), Styles, I. (CoI) & Wang, H. (CoI)
02/02/2026 → …
Project: Research
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R1300CNR: Future Medicines Institute
Scott, C. (PI), Bruce, I. (CoI), Burden, R. (CoI), Burrows, J. (CoI), Collins, B. (CoI), Harrison, T. (CoI), James, J. (CoI), Kennedy, R. (CoI), Lawler, M. (CoI), Longley, D. (CoI), Maguire, S. (CoI), Malinova, D. (CoI), Maule, A. (CoI), McCloskey, K. (CoI), McDade, S. (CoI), Salto-Tellez, M. (CoI), Savage, K. (CoI), Stitt, A. (CoI) & Williams, R. (CoI)
15/10/2024 → …
Project: Research
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R6749CNR: eHealth Hub: All Island Research Hub for Federated Analysis of Cancer Data
Lawler, M. (PI), James, J. (CoI), McDade, S. (CoI) & Overton, I. (CoI)
19/09/2022 → …
Project: Research
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R1049CNR: The cell death regulator FLIP: evaluation of novel inhibitors in colorectal cancer
Longley, D. (PI), Dunne, P. (CoI), Harrison, T. (CoI), Kerr, E. (CoI) & McDade, S. (CoI)
29/03/2019 → …
Project: Research
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R1135CNR: Exploiting the cancer epigenome to develop a common cancer vaccine
McDade, S. (PI), Jafarnejad, S. M. (CoI) & Scott, C. (CoI)
10/01/2020 → 30/06/2022
Project: Research
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Latent world recovery for multimodal learning with missing modalities
Wang, H., Ren, T., Butler, J., Baker, C., Rafferty, K. & McDade, S., 10 Jun 2026, 26 p.Research output: Working paper
File34 Downloads (Pure) -
Mitochondrial metabolism determines chemotherapy sensitivity in colorectal cancer
Moss, D. Y., Brown, C. N., Shaw, A. M., McCann, C., Lewis, N., Downs, M., Wurelly, R., Cunningham, C., Philips, A., Doherty, N., Gallagher, S., McDaid, W. J., Roe, A., Coughlan, A. Y., Cavanagh, B., Ormsby, C., Falcone, F., McCole, R., Monteith, S. & Rogan, E. & 29 others, , 23 Jul 2026, (Early online date) In: Nature Metabolism. 36 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)9 Downloads (Pure) -
Spatial analyses implicate high stromal tumour-infiltrating CD8 + lymphocytes as a negative predictive marker for chemotherapy in estrogen receptor-positive breast cancer
Kinsella, Z., Jahangir, C. A., Nyarko, H. N., Kalinska-Lysiak, D., Gonzalez, C. A., Murphy, V., O’Grady, T., Fay, J., Sheehan, K., Rahman, A., Crown, J. P., Kelly, C. M., McDade, S. S., Woods, I., Connolly, N. M. C., Prehn, J. H. M., Gallagher, W. M. & O’Connor, D. P., 23 Jun 2026, In: Nature Communications. 17, 19 p., 4863.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)18 Downloads (Pure) -
High-resolution spatial proteomics characterises colorectal cancer consensus molecular subtypes
Kisakol, B., Sturrock, A., Cho, S., Azimi, M., Lindner, A. U., Salvucci, M., McDonough, E., Fay, J., O'Grady, T., McCawley, N., Burke, J. P., McNamara, D. A., Graf, J., McDade, S., Longley, D. B., Ginty, F. & Prehn, J. H. M., 08 Jul 2025, BioRxiv, 25 p.Research output: Working paper
File120 Downloads (Pure) -
ClassifieR 2.0: expanding interactive gene expression-based stratification to prostate and high-grade serous ovarian cancer
McCabe, A., Quinn, G. P., Jain, S., Ó Dálaigh, M., Dean, K., Murphy, R. G. & McDade, S. S., 21 Nov 2024, In: BMC Bioinformatics. 25, 13 p., 362.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)36 Downloads (Pure)
Prizes
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Department for the Economy (DfE) Higher Education Research Capital Grant Funding
Ward, C. (Recipient), Maguire, S. (Recipient), McDade, S. (Recipient) & Simpson, D. (Recipient), 2023
Prize: Other distinction
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Activities
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All-Island Cancer Data Forum
Overton, I. (Member of the organising committee), Lawler, M. (Chair), Kowalczyk, A. (Organiser), Boakye Duah, K. (Organiser), Taggart, F. (Organiser), McDade, S. (Member of the organising committee) & Lawler, M. (Member of the organising committee)
26 Jan 2026 → 27 Jan 2026Activity: Participating in or organising an event types › Participation in conference
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PhD External Examiner
McDade, S. (Examiner)
04 Nov 2024Activity: Examination types › PhD external examination
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AICC Annual Meeting Galway 2024
McDade, S. (President)
25 May 2024Activity: Participating in or organising an event types › Participation in conference
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UK oncology diagnostics hub meeting
McDade, S. (Participant)
07 Mar 2024Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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EACR-AACR-IACR 2024:
McDade, S. (Participant)
27 Feb 2024 → 29 Feb 2024Activity: Participating in or organising an event types › Participation in conference
Press/Media
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Prostate cancer: QUB donation to 'transform' research
25/10/2022
1 Media contribution
Press/Media: Research
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Award of Prostate Cancer UK Resaerch Innovation Award (RIA)
McDade, S. & LaBonte Wilson, M.
04/11/2021
2 Media contributions
Press/Media: Research
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Queen's University receives huge grant to boost research into prostate cancer
McDade, S., Coulter, J. & LaBonte Wilson, M.
04/11/2021
1 item of Media coverage
Press/Media: Research
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Queen’s University receives huge grants to boost prostate cancer research
McDade, S., Coulter, J. & LaBonte Wilson, M.
02/11/2021
1 item of Media coverage
Press/Media: Research
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Impacts
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Implementation of HPV-specific testing in addition to assessment of p16 expression in oropharyngeal squamous cell carcinoma
Craig, S. (Participant), Anderson, L. (Participant), Schache, A. (Participant), Moran, M. (Participant), Graham, L. (Participant), Currie, K. (Participant), Rooney, K. (Participant), Robinson, M. (Participant), Upile, N. (Participant), Brooker, R. (Participant), Mesri, M. (Participant), Bingham, V. (Participant), Cuschieri, K. (Participant), McQuaid, S. (Participant), Jones, T. (Participant), McCance, D. (Participant), Salto-Tellez, M. (Participant), McDade, S. (Participant) & James, J. (Participant)
Impact: Health Impact, Quality of Life Impact