• Room 02.004 - David Keir Building

    United Kingdom

Accepting PhD Students

PhD projects

1) Synthesis of antimicrobial peptides 2) Structural and mechanistic studies on antimicrobial peptides 3) Development of chemical probes to study novel antimicrobial targets

20112020

Research output per year

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Personal profile

Research Interests

Our lab uses the tools of organic synthesis, genetic engineering and molecular biology to study novel enzymatic processes, antimicrobial resistance mechanisms and the mechanism of action of antimicrobial and anticancer peptides

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Research Output

Breaking down the cell wall: strategies for antibiotic discovery targeting bacterial transpeptidases

Cochrane, S. & Lohans, C. T., 19 Mar 2020, (Accepted) In : European journal of medicinal chemistry.

Research output: Contribution to journalReview article

  • Observation of the Unbiased Conformers of Putative DNA-Scaffold Ribosugars

    Calabrese, C., Uriarte, I., Vallejo-Lopez, M., Basterretxea, F., Cochrane, S., Davis, B., Corzana, F. & Cocinero, E. J., 2020, In : ACS Central Science. 6, 2, p. 293-303 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 20 Downloads (Pure)

    A Chemical-Intervention Strategy to Circumvent Peptide Hydrolysis by D-Stereoselective Peptidases

    Bann, S., Ballantine, R., Li, Y-X., Qian, P-Y. & Cochrane, S., 27 Nov 2019, In : Journal of Medicinal Chemistry. 62, 22, p. 10466-10472

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    61 Downloads (Pure)

    Dissecting the binding interactions of teixobactin with the bacterial cell wall precursor lipid II

    Chiorean, S., Antwi, I., Carney, D., Kotsogianni, I., Giltrap, A., Alexander, F. M., Cochrane, S. A., Payne, R., Martin, N., Henninot, A. & Vederas, J., 24 Sep 2019, In : ChemBioChem. 6 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Tridecaptin-Inspired Antimicrobial Peptides with Activity Against Multidrug-Resistant Gram-Negative Bacteria

    Ballantine, R., McCallion, C. E., Nassour, E., Tokajian, S. & Cochrane, S., 12 Mar 2019, In : Med Chem Commun. 10, 3, p. 484-487 4 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Citations (Scopus)
    137 Downloads (Pure)

    Prizes

    Sir Henry Wellcome Postdoctoral Fellowship

    Cochrane, Stephen (Recipient), 23 Nov 2015

    Prize: Fellowship awarded competitively

    Thieme Chemistry Journals Award

    Cochrane, Stephen (Recipient), 27 Nov 2018

    Prize: Prize (including medals and awards)

  • Activities

    School of Chemistry UCAS Applicants Open Day

    Stephen Cochrane (Organiser)

    01 Feb 2020

    Activity: Participating in or organising an event typesParticipation in Festival/Exhibition

    Journal of Medicinal Chemistry (Journal)

    Stephen Cochrane (Peer reviewer)

    27 May 2020

    Activity: Publication peer-review and editorial work typesPublication peer-review

    External Examiner

    Stephen Cochrane (Examiner)

    22 May 2020

    Activity: Examination typesPGT external examination

    Peer Review of EPSRC Standard Grant Application

    Stephen Cochrane (Reviewer)

    26 May 2020

    Activity: Other activity typesOther

    2020 Chemical Biology and Bio-Organic Group (CBBG) Forum

    Stephen Cochrane (Participant)

    10 Jan 2020

    Activity: Participating in or organising an event typesParticipation in conference