Stuart Elborn


  • 90 Lisburn Road

    United Kingdom

1991 …2020

Research output per year

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Personal profile

Research Statement

My main focus is Cystic Fibrosis focused on understanding pathophysiology of infection and inflammation and the translation of new therapies into clinical practice. This programme of work is undertaken with laboratory and clinical collaborators in QUB. This includes a significant commitment from the NICRN (Respiratory Health) where I am PI on 6 current clinical trials. I have smaller programmes with others in COPD, bronchiectasis, lung cancer including clinical trials. My research is funded by grants from government agencies, charitable bodies, industry and money raised from clinical trials. I have developed a clinical trials network for Respiratory Health funded by the Northern Ireland Research and Development Office.

In all my research I endeavour to bring scientists and clinicians together to promote inter-disciplinary research. I have been successful in developing programmes of research across disciplines, hospitals and universities in Northern Ireland and across the UK and Europe.

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Research Output

A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation

Ramsey, B. W., Davies, J., McElvaney, N. G., Tullis, E., Bell, S. C., Drevinek, P., Griese, M., McKone, E. F., Wainwright, C. E., Konstan, M. W., Moss, R., Ratjen, F., Sermet-Gaudelus, I., Rowe, S. M., Dong, Q., Rodriguez, S., Yen, K., Ordonez, C. & Elborn, J. S., 03 Nov 2011, In : New England Journal of Medicine. 365, 18, p. 1663-1672 10 p.

Research output: Contribution to journalArticle

Open Access
  • 1213 Citations (Scopus)
    428 Downloads (Pure)

    Detection of Anaerobic Bacteria in High Numbers in Sputum from Patients with Cystic Fibrosis

    Tunney, M. M., Field, T. R., Moriarty, T. F., Patrick, S., Doering, G., Muhlebach, M. S., Wolfgang, M. C., Boucher, R., Gilpin, D. F., McDowell, A. & Elborn, J. S., 01 May 2008, In : American Journal of Respiratory and Critical Care Medicine. 177, 9, p. 995-1001 7 p.

    Research output: Contribution to journalArticle

  • 317 Citations (Scopus)

    Use of culture and molecular analysis to determine the effect of antibiotic treatment on microbial community diversity and abundance during exacerbation in patients with cystic fibrosis

    Tunney, M. M., Klem, E. R., Fodor, A. A., Gilpin, D. F., Moriarty, T. F., McGrath, S. J., Muhlebach, M. S., Boucher, R. C., Cardwell, C., Doering, G., Elborn, J. S. & Wolfgang, M. C., Jul 2011, In : Thorax. 66, 7, p. 579-584 6 p.

    Research output: Contribution to journalArticle

  • 127 Citations (Scopus)
    4 Downloads (Pure)

    Incidence and risk factors for pulmonary exacerbation treatment failures in cystic fibrosis patients chronically infected with Pseudomonas aeruginosa

    Parkins, M. D., Rendall, J. C. & Elborn, S., Feb 2012, In : Chest. 141, 2, p. 485-493 9 p.

    Research output: Contribution to journalArticle

  • 72 Citations (Scopus)

    Lung function and microbiota diversity in cystic fibrosis

    Cuthbertson, L., Walker, A. W., Oliver, A. E., Rogers, G. B., Rivett, D. W., Hampton, T. H., Ashare, A., Elborn, J. S., De Soyza, A., Carroll, M. P., Hoffman, L. R., Lanyon, C., Moskowitz, S. M., O'Toole, G. A., Parkhill, J., Planet, P. J., Teneback, C. C., Tunney, M. M., Zuckerman, J. B., Bruce, K. D. & 1 others, Van Der Gast, C. J., 02 Apr 2020, In : Microbiome. 8, 13 p., 45.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Citations (Scopus)
    105 Downloads (Pure)


    Improving outcomes for people with cystic fibrosis through evidence based clinical trials

    Stuart Elborn (Participant), Lorraine Martin (Participant), Damian Downey (Participant), Simon Brockbank (Participant) & Madeleine Ennis (Participant)

    Impact: Health Impact, Quality of Life Impact


    Infection, inflammation and biomarkers in Cystic Fibrosis

    Author: Addy, C., Jul 2019

    Supervisor: Downey, D. (Supervisor), Elborn, S. (Supervisor) & Bradley, J. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    Nutrition, Inflammation and Lung Function in Middle-aged Men

    Author: Cullen, K., Jul 2010

    Supervisor: Elborn, S. (Supervisor), Kee, F. (Supervisor) & Young, I. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy