Projects per year
Personal profile
Research Interests
I am an ambitious and compassionate Professor and Honorary Consultant of Clinical Oncology, an international authority in the management of prostate cancer with advanced radiotherapy and systemic therapies. I am a Co-Director for the Belfast Manchester FASTMAN Movember/ Prostate Cancer UK Centre of Excellence programme.
My clinical academic focus is localised and advanced prostate cancer. I am very interested in hypofractionated radiotherapy as a means to escalate radiation dose to tumour and improve outcomes for men with locally advanced prostate cancer. This radiotherapy can be optimally delivered with High Dose Rate brachytherapy or with Image Guided Stereotactic Ablative Radiotherapy (SABR). I am the Chief Investigator on a clinical-translational study of prostate SABR and two studies in prostate cancer. I have been local PI on 17 clinical trials, I'm a member of 9 Trial Mangement Groups.
Translational Research
I collaborate extensively with an interdisciplinary group of academics aimed at modelling modern radiotherapy treatments in vitro and in vivo. We have been comparing different methods of delivering high dose hypofractionated radiotherapy for the treatment of prostate cancer.
I am also interested in biomarkers and the utilisation of nanotechnology to enhance the effects of radiation therapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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R6633CNR: ORIGIN: Optical fibRe dose ImaGINg for adaptive brachytherapy
Prise, K. (PI) & Jain, S. (CoI)
11/11/2019 → …
Project: Research
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R4684CNR: Movember COE
Jain, S. (PI), Cole, A. (CoI), O'Sullivan, J. (CoI) & Prise, K. (CoI)
31/07/2014 → 31/03/2024
Project: Research
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R2116CNR: MOVEMBER CENTRE OF EXCELLENCE
O'Sullivan, J. (PI), Jain, S. (CoI), Kennedy, R. (CoI), McDade, S. (CoI), Prise, K. (CoI), Salto-Tellez, M. (CoI) & Waugh, D. (CoI)
21/05/2014 → 30/06/2019
Project: Research
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A modified Delphi consensus regarding the clinical utility of triplet therapy in patients with metastatic hormone-sensitive prostate cancer patients in the UK
Glen, H., Bahl, A., Fleure, L., Clarke, N., Jain, S., Kalsi, T., Khoo, V. & Mobeen, J., 26 Nov 2024, In: BMJ Open. 14, 11, e090013.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
A multimodality assessment of the protective capacity of statin therapy in a mouse model of radiation cardiotoxicity
Walls, G. M., Ghita, M., Herron, B., Edgar, K. S., Kuburas, R., Watson, C. J., Grieve, D. J., Cole, A. J., Jain, S. & Butterworth, K. T., Jan 2024, In: Radiotherapy and Oncology. 190, 8 p., 110004.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)42 Downloads (Pure) -
A potential biomarker of radiosensitivity in metastatic hormone sensitive prostate cancer patients treated with combination external beam radiotherapy and radium-223
Redmond, K. M., Turner, P. G., Cole, A., Jain, S., Prise, K. M. & O'Sullivan, J. M., Feb 2024, In: Radiotherapy and Oncology. 191, 9 p., 110063.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Downloads (Pure) -
Associations of prostate tumor immune landscape with vigorous physical activity and prostate cancer progression
Huang, L., Winter, S. J., Olsson, L. T., Hamilton, A. M., Halliday, S. R., Kirk, E. L., Farnan, L., Gerstel, A., Craig, S. G., Finn, S. P., LaBonte Wilson, M., Jain, S., Troester, M. A., Butler, E. N., Bensen, J. T., Wobker, S. E. & Allott, E. H., 01 Dec 2024, In: Cancer Epidemiology Biomarkers & Prevention. 33, 12, p. 1623-1632Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure) -
Baseline cardiac parameters as biomarkers of radiation cardiotoxicity in lung cancer: an NI-HEART analysis
Walls, G. M., Hill, N., McMahon, M., Kearney, B. Ó., McCann, C., McKavanagh, P., Giacometti, V., Cole, A. J., Jain, S., McGarry, C. K., Butterworth, K., McAleese, J., Harbinson, M. & Hanna, G. G., 20 Aug 2024, In: JACC: CardioOncology. 6, 4, p. 529-540 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)9 Downloads (Pure)
Prizes
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3rd Year PhD symposium prize - Charles Haughey
Jain, S. (Recipient), 13 Jun 2019
Prize: Other distinction
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CCRCB Student of the Year - Charles Haughey
Jain, S. (Recipient), 13 Jan 2020
Prize: Other distinction
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Activities
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2020 National Cancer Research Institute Cancer Conference
Jain, S. (Organiser)
02 Nov 2020 → 04 Nov 2020Activity: Participating in or organising an event types › Participation in conference
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Stereotactic radiotherapy with hydrogel spacing
Jain, S. (Invited speaker)
05 Apr 2020Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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PGJCCR Open Day
Jain, S. (Participant)
15 Feb 2020Activity: Participating in or organising an event types › Participation in Festival/Exhibition
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University of Limerick (External organisation)
Jain, S. (Advisor)
06 Feb 2020 → 07 Feb 2020Activity: Membership types › Membership of network
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Advanced radiotherapy for prostate cancer
Jain, S. (Invited speaker)
04 Feb 2020Activity: Talk or presentation types › Invited or keynote talk at national or international conference
Press/Media
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Prostate Cancer Centre of Excellence
Jain, S., Cole, A. & O'Sullivan, J.
21/10/2022
1 item of Media coverage
Press/Media: Public Engagement Activities
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Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial.
10/12/2019
1 Media contribution
Press/Media: Research
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CT Radiomics in Prostate Cancer
28/09/2019 → 01/12/2019
1 item of Media coverage, 1 Media contribution
Press/Media: Public Engagement Activities
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Belfast trials aim for improved prostate cancer treatment
08/08/2018
1 item of Media coverage
Press/Media: Research
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Prostate cancer treatment breakthrough at Queen's University of Belfast
08/08/2018
1 item of Media coverage
Press/Media: Research