Projects per year
Personal profile
Research Statement
My research is centred on promoting bone repair and in developing novel biomaterials for bone graft replacement. My current research projects include investigating novel bioactives from marine organisms to stimulate bone formation, controling the resorption of orthopaedic implants and investigating predictors of the adult progenitor cell reserve.
Other
Leadership Roles (QUB)
Chair of the Animal Welfare and Ethical Review Board (current)
Chair of QUB Athena SWAN Network (2015-2020)
School Athena SWAN Co-Champion (2014-2020)
Module co-ordinator for Evidence Based Nursing 2
Leadership Roles (External)
Member of the National Athena SWAN PTO Staff Subgroup (current)
Chair of the Regional AWERB Hub (current)
Founder member of the Athena SWAN Network for Nursing and Midwifery (current)
Treasurer of the Northern Ireland Biomedical Engineering Society
Teaching
Undergraduate modules
Evidence Based Nursing 2, BSc Nursing
Applied Life Science, Year 2, BSc Nursing
Essentials of Pharmacology, Year 2, BSc Nursing
Other
Current Graduate Supervision
Steven McKelvey, Nichola Ejaz, Abdulaziz Alanazi, Mona Alradhdi, Anushree Gastidar (School of Mechanical and Aerospace Eningeering)
Research Interests
Currently Funded Projects
1. Unravelling patient predictors of stem cell expansion in an orthopaedic setting. SA Clarke. DfE and NICRF seed funding.
2. Controlled strontium release from resorbable devices to improve osteoporotic fracture fixation. FJ Buchanan, SA Clarke. Dunhill Medical Trust.
Completed Research Projects
1. Demonstrating superior performance of novel medical implants. FJ Buchanan, SA Clarke. INVEST NI Proof of Concept Phase 2 and PoC Plus extension.
2. Potential osteogenicity of marine extracts from Irish waters: screening for bioactivity. SA Clarke
3. Marine inspired biosilica-filled adhesive complex coacervates: DimDOM. Personal fellowship for PJ Walsh. Co-applicants: J Bothwell, SA Clarke. Marie Curie Outgoing Fellowship, EU funded Programme.
4. Evaluation of the osteogenic properties of a marine based tricomposite. H McMahon, SA Clarke. MSc Bursary, Insitute of Technology Tralee.
5. Computer simulation of biodegradation scaffolds: Validation against experiments and implementation for tissue engineering. P Prendergast, F Buchanan, N Dunne, SA Clarke.Science Foundation Ireland funding- North-Supplement scheme
6. Simulation of cell mediated bioresorption of calcium phosphate bone substitutes. FJ Buchanan, NJ Dunne, SA Clarke, Robert Mathys Foundation
7. Calcium Phosphate Cements for Bone Augmentation through Vertebroplasty R Wilcox, F Buchanan, N Dunne, SA Clarke, J Orr, D Barton EPSRC
8. Changes in the Osteogenic potential of Bone Marrow Stromal Cells with ageing. SA Clarke, DR Marsh. Smith and Nephew Orthopaedics
9. Gene Therapy for Osteogenesis Imperfecta. G J Farrar, S Millington-Ward, GR Jordan, SA Clarke, DR Marsh. Ireland-Northern Ireland Co-operation – Research Project Grants, R&D Office.
10. The stimulation of new bone formation around a tibial implant using simvastatin. N Rushton and SA Clarke. Arthritis Research Campaign
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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R6371BSC: DiaDom EU FP7 2011-IOF-302494
Clarke, S. (PI) & Walsh, P. (CoI)
01/08/2011 → 13/03/2015
Project: Research
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R1819MEE: Calcium phosphate cements for bone augmentation through vertebroplasty<MECH&AERO/MED&DENT>
Buchanan, F. (PI), Clarke, S. (CoI), Dunne, N. (CoI) & Orr, J. (CoI)
01/08/2006 → 31/12/2010
Project: Research
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3D-printing of dipyridamole/thermoplastic polyurethane materials for bone regeneration
Adhami, M., Dastidar, A. G., Anjani, Q. K., Detamornrat, U., Tarrés, Q., Delgado-Aguilar, M., Acheson, J. G., Manda, K., Clarke, S. A., Moreno-Castellanos, N., Larrañeta, E. & Domínguez-Robles, J., 22 Nov 2024, (Early online date) In: Drug Delivery and Translational Research. 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)17 Downloads (Pure) -
Marine-derived materials for hard tissue repair and regeneration
Clarke, S. A. & Walsh, P. J., 17 Jul 2024, Handbook of the extracellular matrix: biologically-derived materials. Maia, F. R., Oliveira, J. M. & Reis, R. L. (eds.). Springer, p. 1207–1230Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
9 Downloads (Pure) -
Development of a novel marine-derived tricomposite biomaterial for bone regeneration
Aslam, B., Augustyniak, A., Clarke, S. A. & McMahon, H., Sept 2023, In: Marine Drugs. 21, 9, 473.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)41 Downloads (Pure) -
Investigating the regenerative potential of 3D-printed PLLGA/alginate composite scaffolds for the treatment of articular cartilage defect
Ghosh Dastidar, A., Clarke, S., Larrañeta, E., Buchanan, F., Rana, S., J Kelly, D. & Manda, K., 04 Sept 2023.Research output: Contribution to conference › Abstract › peer-review
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In vitro degradation of 3D-printed poly(L-lactide-co-glycolic acid) scaffolds for tissue engineering applications
Ghosh Dastidar, A., Clarke, S. A., Larrañeta, E., Buchanan, F. & Manda, K., 09 Sept 2023, In: Polymers. 15, 18, 18 p., 3714.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)48 Downloads (Pure)
Prizes
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Awarded "Best Paper of 2016" by the editors of Journal of Materials Science: Materials in Medicine
Clarke, S. (Recipient) & Buchanan, F. (Recipient), 06 Sept 2017
Prize: Prize (including medals and awards)
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Inaugural BORS/ORS Travelling Fellowship
Clarke, S. (Recipient), Oct 2007
Prize: Prize (including medals and awards)
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Lilian Bradley Award for Best Oral Presentation
Clarke, S. (Recipient), Mar 2010
Prize: Prize (including medals and awards)
Activities
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SistersIN Mentoring training
Moran, C. (Speaker) & Clarke, S. (Speaker)
17 Oct 2024Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Invited Seminar at Dept of Biomedical Engineering
Clarke, S. (Advisor)
18 Apr 2024Activity: Talk or presentation types › Invited talk
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The Diversity Data Gap
Clarke, S. (Invited speaker)
27 Jan 2024Activity: Talk or presentation types › Invited or keynote talk at national or international conference
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Bioengineering in Ireland 2024: 29th annual conference
Clarke, S. (Organiser)
26 Jan 2024Activity: Participating in or organising an event types › Participation in conference
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European Cells and Materials (ECM) (Journal)
Clarke, S. (Peer reviewer)
06 Jan 2024Activity: Publication peer-review and editorial work types › Publication peer-review