• Room 06.327 - Medical Biology Centre

    United Kingdom

Accepting PhD Students

20012023

Research activity per year

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Personal profile

Research Statement

My research is centred on promoting bone repair and in developing novel biomaterials for bone graft replacement. My current research projects include investigating novel bioactives from marine organisms to stimulate bone formation, controling the resorption of orthopaedic implants and investigating predictors of the adult progenitor cell reserve.

Other

Leadership Roles (QUB)

Chair of the Animal Welfare and Ethical Review Board (current)

Chair of QUB Athena SWAN Network (2015-2020)

School Athena SWAN Co-Champion (2014-2020)

Module co-ordinator for Evidence Based Nursing 2

 

Leadership Roles (External)

Member of the National Athena SWAN PTO Staff Subgroup (current)

Chair of the Regional AWERB Hub (current)

Founder member of the Athena SWAN Network for Nursing and Midwifery (current)

Treasurer of the Northern Ireland Biomedical Engineering Society

Teaching

Undergraduate modules

Evidence Based Nursing 2, BSc Nursing
Applied Life Science, Year 2, BSc Nursing
Essentials of Pharmacology, Year 2, BSc Nursing

Other

Current Graduate Supervision

Steven McKelvey, Nichola Ejaz, Abdulaziz Alanazi, Mona Alradhdi, Anushree Gastidar (School of Mechanical and Aerospace Eningeering)

Research Interests

Currently Funded Projects

1. Unravelling patient predictors of stem cell expansion in an orthopaedic setting. SA Clarke. DfE and NICRF seed funding.

2. Controlled strontium release from resorbable devices to improve osteoporotic fracture fixation. FJ Buchanan, SA Clarke. Dunhill Medical Trust.

 

Completed Research Projects

1. Demonstrating superior performance of novel medical implants. FJ Buchanan, SA Clarke. INVEST NI Proof of Concept Phase 2 and PoC Plus extension.

2. Potential osteogenicity of marine extracts from Irish waters: screening for bioactivity. SA Clarke

3. Marine inspired biosilica-filled adhesive complex coacervates: DimDOM. Personal fellowship for PJ Walsh. Co-applicants: J Bothwell, SA Clarke. Marie Curie Outgoing Fellowship, EU funded Programme. 

4. Evaluation of the osteogenic properties of a marine based tricomposite. H McMahon, SA Clarke. MSc Bursary, Insitute of Technology Tralee.

5. Computer simulation of biodegradation scaffolds: Validation against experiments and implementation for tissue engineering. P Prendergast, F Buchanan, N Dunne, SA Clarke.Science Foundation Ireland funding- North-Supplement scheme

6. Simulation of cell mediated bioresorption of calcium phosphate bone substitutes. FJ Buchanan, NJ Dunne, SA Clarke, Robert Mathys Foundation

7. Calcium Phosphate Cements for Bone Augmentation through Vertebroplasty R Wilcox, F Buchanan, N Dunne, SA Clarke, J Orr, D Barton EPSRC

8. Changes in the Osteogenic potential of Bone Marrow Stromal Cells with ageing. SA Clarke, DR Marsh. Smith and Nephew Orthopaedics

9. Gene Therapy for Osteogenesis Imperfecta.  G J Farrar, S Millington-Ward, GR Jordan, SA Clarke, DR Marsh. Ireland-Northern Ireland Co-operation – Research Project Grants, R&D Office.

10. The stimulation of new bone formation around a tibial implant using simvastatin. N Rushton and SA Clarke. Arthritis Research Campaign   

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water
  • SDG 15 - Life on Land
  • SDG 16 - Peace, Justice and Strong Institutions

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