Tianbao Chen

Professor

  • Room 03.031 - Whitla Medical Building Block 97B MBC Site

    United Kingdom

Accepting PhD Students

20002019
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Research Output 2000 2019

2019
Open Access
File
Bombesin
Smooth Muscle
Muscle
Rats
Skin
Open Access
File
Bradykinin
Anura
Smooth Muscle
Muscle
Skin
Open Access
File
Tarsiidae
Skin
Cells
Cell membranes
Microorganisms

A Novel Kunitzin-Like Trypsin Inhibitor Isolated from Defensive Skin Secretion of Odorrana versabilis

Dong, Y., Shi, D., Ying, Y., Xi, X., Chen, X., Wang, L., Zhou, M., Wu, Q., Ma, C. & Chen, T., 28 Jun 2019, In : Biomolecules. 9, 7, 14 p., 254.

Research output: Contribution to journalArticle

Open Access
File
Trypsin Inhibitors
Trypsin
Skin
Peptides
Bamboo
3 Citations (Scopus)
Methicillin Resistance
Methicillin
Cystic Fibrosis
Anura
Skin
1 Citation (Scopus)

Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and Its Truncated Analogues

Zhou, X., Shi, D., Zhong, R., Ye, Z., Ma, C., Zhou, M., Xi, X., Wang, L., Chen, T. & Kwok, H. F., 25 Jun 2019, In : Biomolecules. 9, 6, 15 p., 249.

Research output: Contribution to journalArticle

Open Access
File
Rana pipiens
Anura
Skin
Peptides
Staphylococcus aureus

Boiling Licorice Produces Self-assembled Protein Nanoparticles: A Novel Source of Bioactive Nanomaterials

Zhou, J., Zhang, J., Gao, G., Wang, H., He, X., Chen, T., Ke, L., Rao, P. & Wang, Q., 24 Jul 2019, In : Journal of Agricultural and Food Chemistry.

Research output: Contribution to journalArticle

Glycyrrhiza
licorice
nanomaterials
Nanostructures
nanoparticles

Cloning of a Novel Trypsin Inhibitor from the Traditional Chinese Medicine Decoction Pieces, Radix Trichosanthis

Sang, M., Ying, Y., Wu, Q., Ma, C., Xi, X., Zhou, M., Wang, L., Bininda-Emonds, O. & Chen, T., 01 Mar 2019, In : Analytical Biochemistry.

Research output: Contribution to journalArticle

Trypsin Inhibitors
Cloning
Chinese Traditional Medicine
Medicine
Organism Cloning
Open Access
File
Cystic Fibrosis
Dimyristoylphosphatidylcholine
Derivatives
Peptides
Hydrophobicity

Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor

Miao, Y., Chen, G., Xi, X., Ma, C., Wang, L., Burrows, J. F., Duan, J., Zhou, M. & Chen, T., 14 Jul 2019, In : Biomolecules. 9, 7, 13 p., 280.

Research output: Contribution to journalArticle

Open Access
File
Protease Inhibitors
Peptides
Trypsin
Skin
Lysine

Effects of TAT-SOD at Acupoints on Essential Hypertension by Monitoring Meridians Electrical Potential

Guo, J., Xu, J., Chen, T., Xu, M., Liu, S., Zhang, C., Ke, L., Zhou, J., Wang, Q. & Rao, P-F., 15 Oct 2019, In : Chinese journal of integrative medicine. 7 p.

Research output: Contribution to journalArticle

Meridians
Acupuncture Points
Blood Pressure
Superoxides
Essential Hypertension
1 Citation (Scopus)
Open Access
File
secretions
Bioactivity
peptides
Skin
membranes

Inhibition of ENaC Activity by Novel Peptide Trypsin-Like Inhibitors Derived from Amphibian Skin Secretions

Carroll, E., Douglas, L., Reihill, J., Zhou, M., Chen, T., McGarvey, L., Lundy, F., Hollywood, M., Lockhart, J. & Martin, L., 01 Apr 2019, In : The FASEB Journal. 33, Suppl. 1, 127.9.

Research output: Contribution to journalMeeting abstract

LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi

Li, B., Lyu, P., Xie, S., Qin, H., Pu, W., Xu, H., Chen, T., Shaw, C., Ge, L. & Kwok, H. F., 21 Jun 2019, In : Biomolecules. 9, 6, 13 p., 242.

Research output: Contribution to journalArticle

Open Access
File
Anura
Skin
Peptides
Bacteria
Amphibians
Open Access
File
Structure-Activity Relationship
Hydrophobic and Hydrophilic Interactions
Peptides
Anti-Bacterial Agents
Skin

Unravelling the Skin Secretion Peptides of the Gliding Leaf Frog, Agalychnis spurrelli (Hylidae)

Proaño-Bolaños, C., Blasco-Zúñiga, A., Rafael Almeida, J., Wang, L., Angel Llumiquinga, M., Rivera, M., Zhou, M., Chen, T. & Shaw, C., 30 Oct 2019, In : Biomolecules. 9, 11, 20 p., 667.

Research output: Contribution to journalArticle

Open Access
File
Anura
Skin
Peptides
Microbial Sensitivity Tests
Candida

Visualising reactive oxygen species in live mammals and revealing of ROS-related system

Guo, J., Xu, H., Wang, Z., Liu, S., Dai, Y., Lu, J., Zheng, S., Xu, D., Zhou, J., Ke, L., Cheng, X., Xu, M., Zhang, X., Guo, Y., Lin, Y., Ding, W., Gao, G., Wang, H., Chen, Q., Yu, X. & 19 othersChen, H., Qin, L., Sun, X., Li, Z., Zheng, S., Wang, J., Cheng, Y., Qiu, S., Hu, Y., Huang, P., Lin, C., Wu, Q., Li, Y., Chen, T., Shaw, C., Ho, S., Wang, Q., Gu, H. & Rao, P., 21 Oct 2019, In : Free Radical Research. 11 p.

Research output: Contribution to journalArticle

Mammals
Reactive Oxygen Species
Electrons
Fascia
Tissue
2018
2 Citations (Scopus)

A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea

Zhang, L., Chen, X., Wu, Y., Zhou, M., Ma, C., Xi, X., Chen, T., Walker, B., Shaw, C. & Wang, L., 11 Apr 2018, In : Scientific Reports. 8, 9 p., 5851.

Research output: Contribution to journalArticle

Open Access
File
Chymotrypsin
Peptides
Proteasome Endopeptidase Complex
Trypsin Inhibitors
Cloning
2 Citations (Scopus)

A novel antimicrobial peptide, Ranatuerin-2PLx (R2PLx), showing therapeutic potential in inhibiting proliferation of cancer cells

Chen, X., Zhang, L., Ma, C., Zhang, Y., Xi, X., Wang, L., Zhou, M., Burrows, J. F. & Chen, T., Dec 2018, In : Bioscience Reports. 38, 6, 11 p., BSR20180710.

Research output: Contribution to journalArticle

Open Access
File
Cells
Cell Proliferation
Peptides
Neoplasms
Ranidae
2 Citations (Scopus)
Open Access
File
Potassium Channels
Insulin
Peptides
Anura
Glucose
3 Citations (Scopus)
Open Access
File
Hydrophobicity
Bioactivity
Hydrophobic and Hydrophilic Interactions
Skin
Peptides

Comparative Profiling of Three Atheris Snake Venoms: A. squamigera, A. nitschei and A. chlorechis

Wang, H., Chen, X., König, E., Zhou, M., Wang, L., Chen, T. & Shaw, C., Aug 2018, In : The Protein Journal. 37, 4, p. 353-360

Research output: Contribution to journalArticle

Open Access
File
Snake Venoms
Venoms
Proteins
Proteomics
Size exclusion chromatography
Cystic Fibrosis
Methicillin-Resistant Staphylococcus aureus
Peptides
Membranes
Biofilms
Dimyristoylphosphatidylcholine
Anura
Bacteria
Skin
Peptides
3 Citations (Scopus)

Discovery of Distinctin-Like-Peptide-PH (DLP-PH) from the Skin Secretion of Phyllomedusa hypochondrialis, a Prototype of a Novel Family of Antimicrobial Peptide

Wu, D., Gao, Y., Tan, Y., Liu, Y., Wang, L., Zhou, M., Xi, X., Ma, C., Bininda-Emonds, O. R. P., Chen, T. & Shaw, C., 23 Mar 2018, In : Frontiers in Microbiology. 9, 11 p., 541.

Research output: Contribution to journalArticle

Open Access
File
Skin
Peptides
Anura
Complementary DNA
distinctin
Open Access
File
Anura
Smooth Muscle
Skin
Peptides
Drug Discovery
2 Citations (Scopus)
Open Access
File
Cytotoxicity
skin (animal)
cytotoxicity
Skin
Fusion reactions
2 Citations (Scopus)
Open Access
File
Ranidae
Bioactivity
Anura
Skin
Peptides
7 Citations (Scopus)

Evaluation of the bioactivity of a mastoparan peptide from wasp venom and of its analogues designed through targeted engineering

Chen, X., Zhang, L., Wu, Y., Wang, L., Ma, C., Xi, X., Bininda-Emonds, O., Shaw, C., Chen, T. & Zhou, M., 01 May 2018, In : International Journal of Biological Sciences. 14, 6, p. 599-607 9 p.

Research output: Contribution to journalArticle

Open Access
File
Wasp Venoms
venom
bioactivity
venoms
wasp
3 Citations (Scopus)
Open Access
File
Rana esculenta
Serine Proteinase Inhibitors
Anura
Peptide Hydrolases
Skin
2 Citations (Scopus)
Open Access
File
Anura
Skin
Bioactivity
Peptides
Bioassay
2 Citations (Scopus)
Open Access
File
Ranidae
Skin
Peptides
Methicillin-Resistant Staphylococcus aureus
Cells
5 Citations (Scopus)
Open Access
File
Bufonidae
Peptides
Water
RNA Sequence Analysis
Anura

Inhibition of ENaC activity by novel peptide trypsin-like inhibitors derived from amphibian skin secretions

Carroll, E. L., Douglas, L. E. J., Reihill, J. A., Zhou, M., Chen, T., McGarvey, L. P., Lundy, F. T., Hollywood, M. A., Crilly, A., Lockhart, J. C. & Martin, S. L., 01 Aug 2018, In : Irish journal of medical science. 187, Suppl 8, p. S250-S251

Research output: Contribution to journalMeeting abstract

2 Citations (Scopus)
Open Access
File
Ranidae
Bacteria
Peptides
Methicillin-Resistant Staphylococcus aureus
Infection
2 Citations (Scopus)

Novel peptide dermaseptin‐PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling

Long, Q., Li, L., Wang, H., Li, M., Wang, L., Zhou, M., Su, Q., Chen, T. & Wu, Y., 21 Nov 2018, In : Journal of Cellular and Molecular Medicine. 23, 2, p. 1300-1312 13 p.

Research output: Contribution to journalArticle

Open Access
File
Apoptosis
Peptides
Cell Membrane
Anura
Neoplasms
1 Citation (Scopus)

Skin secretion transcriptome remains in chromatographic fractions suitable for molecular cloning

Proaño Bolaños, C., Zhou, M., Chen, T. & Shaw, C., 06 Oct 2018, In : Analytical Biochemistry.

Research output: Contribution to journalArticle

Open Access
File
Cloning
Molecular Cloning
Transcriptome
Skin
Amphibians
2017
1 Citation (Scopus)

Antidiabetic Micro-/Nanoaggregates from Ge-Gen-Qin-Lian-Tang Decoction Increase Absorption of Baicalin and Cellular Antioxidant Activity In Vitro

Lin, D., Du, Q., Wang, H., Gao, G., Zhou, J., Ke, L., Chen, T., Shaw, C. & Rao, P., 17 Jul 2017, In : BioMed Research International. 2017, p. 1-8 9217912.

Research output: Contribution to journalArticle

Open Access
File
Hypoglycemic Agents
Antioxidants
Sediments
Pharmacology
Caco-2 Cells
3 Citations (Scopus)

Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats

Liu, S., Long, Q., Xu, Y., Wang, J., Xu, Z., Wang, L., Zhou, M., Wu, Y., Chen, T. & Shaw, C., 30 Nov 2017, In : Oncotarget. 8, 67, p. 111369-111386

Research output: Contribution to journalArticle

Open Access
File
Klebsiella pneumoniae
Wound Healing
Bacteria
Peptides
Re-Epithelialization
8 Citations (Scopus)

A Structural and Functional Analogue of a Bowman Birk-type Protease Inhibitor from Odorrana Schmackeri

Wu, Y., Long, Q., Xu, Y., Guo, S., Chen, T., Wang, L., Zhou, M., Zhang, Y., Shaw, C. & Walker, B., Apr 2017, In : Bioscience Reports. 37, 2

Research output: Contribution to journalArticle

Open Access
File
Tryptases
Protease Inhibitors
Anura
Trypsin
Skin
14 Citations (Scopus)
Open Access
File
Skin
Peptides
Cytotoxicity
Bioactivity
Bacteria
5 Citations (Scopus)
Open Access
File
Bacteria
Skin
Cells
Peptides
Anti-Bacterial Agents
Open Access
File
Antibiotics
Secretion
Conventional
Drugs
Frog
2 Citations (Scopus)

Identification of a Novel Vasodilatory Octapeptide from the Skin Secretion of the African Hyperoliid Frog, Kassina senegalensis

Du, Q., Wang, H., Ma, C., Wu, Y., Xi, X., Zhou, M., Chen, T., Shaw, C. & Wang, L., 19 Jul 2017, In : Molecules. 22, 9 p., 1215.

Research output: Contribution to journalArticle

Open Access
File
Skin
Amides
Peptides
Molecular mass
Muscle
3 Citations (Scopus)

Novel Kazal-type Protease inhibitors from the skin secretion of the Splendid leaf frog, Cruziohyla calcarifer

Proaño Bolaños, C., Li, R., Zhou, M., Wang, L., Xi, X., Tapia, E. E., Coloma, L. A., Chen, T. & Shaw, C., Jun 2017, In : EuPA Open Proteomics. 15, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
File
Protease Inhibitors
Anura
Skin
Biological Phenomena
Cloning
2 Citations (Scopus)
Open Access
File
Bombesin
Muscle
Skin
Peptides
Chromatography
5 Citations (Scopus)
Open Access
File
Biofilms
Cytotoxicity
Skin
Cells
Peptides
2 Citations (Scopus)

Ranatensin-HL: A Bombesin-Related Tridecapeptide from the Skin Secretion of the Broad-Folded Frog, Hylarana latouchii

Lin, Y., Chen, T., Zhou, M., Wang, L., Su, S. & Shaw, C., 04 Jul 2017, In : Molecules. 22, 7, 1110.

Research output: Contribution to journalArticle

Open Access
File
Bombesin
Skin
Peptides
Muscle
Amino Acids