• Room 03.013 - Pharmacy & MCI

    United Kingdom

Accepting PhD Students

PhD projects

Open to PhD applications in the following areas: Biology and genomics of bacteriophages and viruses of archaea; Metatranscriptomics of biofilms; Horizontal gene transfer in biofilms; Antimicrobial discovery; Discovery and engineering of biocatalysts.

20142019
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Research Output 2014 2019

2019
16 Downloads (Pure)

Bacteriophages against Proteus mirabilis Biofilms

Rice, C., Ganacias, C. J., Chai, Z., Flynn, P. B., Gilmore, B. F., Jones, B. V., Irwin, N., Kulakov, L. A. & Skvortsov, T., 20 Sep 2019. 1 p.

Research output: Contribution to conferencePoster

File
Proteus mirabilis
Biofilms
Ammonia
Bacteriophages
Urine
14 Downloads (Pure)

Bacteriophages for Biofilm Eradication

Rice, C., Skvortsov, T., Kumaresan, D., Flynn, P., Gilmore, B. & Kulakov, L., 20 Sep 2019.

Research output: Contribution to conferencePoster

File
Biofilms
Bacteriophages
Stenotrophomonas maltophilia
Proteus mirabilis
Anti-Infective Agents
antibiotic resistance
halite
Triassic
biodiversity
antibiotics
2 Citations (Scopus)
98 Downloads (Pure)
Open Access
File
Transaminases
Salts
Enzymes
Haloferax
Biocatalysis
3 Citations (Scopus)
29 Downloads (Pure)

Effect of soil horizon stratigraphy on the microbial ecology of alpine paleosols

Young, J. M., Skvortsov, T., Kelleher, B. P., Mahaney, W. C., Somelar, P. & Allen, C. C. R., 20 Mar 2019, In : Science of the Total Environment. 657, p. 1183-1193

Research output: Contribution to journalArticle

Open Access
File
Stratigraphy
microbial ecology
Ecology
soil horizon
paleosol

Isolation of Novel Bacteriophages against Cystic Fibrosis-associated Bacteria

Chai, Z., Rice, C., Ganacias, C. J., O'Brien, S., Sherrard, L., Gilmore, B. & Skvortsov, T., 2019.

Research output: Contribution to conferencePoster

Leveraging Structural Relationships as a Novel Mode of Viral Classification

Magill, D., Skvortsov, T., Vincent, OF. & McGrath, J., 2019, p. 42-42. 1 p.

Research output: Contribution to conferencePoster

phylogenetics
protein
gene
holistic approach
bacteriophage

Microbial Stabilization and Kinetic Enhancement of Marine Methane Hydrates

Ghaani, M. R., Allen, C. C. R., Young, J. M., Nandi, P. K., Dandare, S. U., Skvortsov, T. & English, N. J., 26 Nov 2019, In : Geomicrobiology Journal.

Research output: Contribution to journalArticle

Methane
Hydrates
stabilization
Stabilization
methane

Poster abstract: Leveraging structural relationships as a novel mode of viral classification

Magill, D., Skvortsov, T., O’Flaherty, V. & McGrath, J., 01 Mar 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access
phylogenetics
protein
gene
holistic approach
bacteriophage

Poster abstract: Understanding the evolution and metabolic capabilities of the Butyrivibrio group

Pidcock, S., Skvortsov, T., Santos, F., Ting, K. S., Creevey, C. & Huws, S., 01 Mar 2019, In : Access Microbiology. 1, 1A, 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
Butyrivibrio
Pseudobutyrivibrio
genome
glycosidases
biohydrogenation

Profiling the microbial community of a Triassic halite deposit in Northern Ireland: an environment with significant potential for biodiscovery

Megaw, J., Kelly, S. A., Thompson, T. P., Skvortsov, T. & Gilmore, B. F., 28 Nov 2019, In : FEMS Microbiology Letters. 366, 22, 11 p., fnz242.

Research output: Contribution to journalArticle

Northern Ireland
Microbiota
Metagenome
Metagenomics
Culture Techniques
25 Downloads (Pure)

Understanding autotrophic bacterial community structure and function along a naturally occurring iron deposit gradient

Cunningham, M., Macintosh, K. A., Chiang, Y-C., Seetaloo, N., Dandare, S., Rice, C., Skvortsov, T., Griffiths, D., McGrath, J. & Kumaresan, D., 08 Apr 2019.

Research output: Contribution to conferencePoster

File

Understanding the evolution and metabolic capabilities of the Butyrivibrio group

Pidcock, S., Skvortsov, T., Godoy Santos, F., Siu-Ting, K., Creevey, C. & Huws, S., 2019, p. 270-270. 1 p.

Research output: Contribution to conferencePoster

Butyrivibrio
Pseudobutyrivibrio
genome
glycosidases
biohydrogenation
2018
1 Citation (Scopus)
66 Downloads (Pure)

Characterization of a novel ω-transaminase from a Triassic salt mine metagenome

Kelly, S. A., Skvortsov, T., Magill, D., Quinn, D. J., McGrath, J. W., Allen, C. C. R., Moody, T. S. & Gilmore, B. F., 01 Sep 2018, In : Biochemical and Biophysical Research Communications. 503, 4, p. 2936-2942 7 p.

Research output: Contribution to journalArticle

Open Access
File
Salt mines
Metagenome
Transaminases
Salts
Metagenomics
202 Downloads (Pure)

Draft genome sequence of Rhodococcus sp. strain NCIMB 12038, a naphthalene-degrading bacterium

Dandare, S. U., Skvortsov, T., Arkhipova, K. & Allen, C. C. R., 04 Jan 2018, In : Genome Announcements. 6, 1, e01420-17.

Research output: Contribution to journalArticle

Open Access
File
Rhodococcus
Biotransformation
Genome
Bacteria
Genes
1 Citation (Scopus)
190 Downloads (Pure)

Draft genome sequence of the predatory marine bacterium Halobacteriovorax sp. strain JY17

Young, J. M., Skvortsov, T., Arkhipova, K. & Allen, C. C. R., 01 Jan 2018, In : Genome Announcements. 6, 1, p. 1-2 e01416-17.

Research output: Contribution to journalArticle

Open Access
File
Genome
Bacteria
Metagenomics
Transfer RNA
rRNA Genes
1 Citation (Scopus)
123 Downloads (Pure)

Draft genome sequences of Pseudomonas putida UV4 and UV4/95, toluene dioxygenaseexpressing producers of cis-1,2-dihydrodiols

Skvortsov, T., Hoering, P., Arkhipova, K., Whitehead, R. C., Boyd, D. R. & Allen, C. C. R., 04 Jan 2018, In : Genome Announcements. 6, 1, p. 1-2 e01419-17.

Research output: Contribution to journalArticle

Open Access
File
Pseudomonas putida
Phenols
Toluene
Alkenes
Biotransformation

Investigating the evolutionary divergence of the Butyrivibrio group

Pidcock, S., Skvortsov, T., Godoy Santos, F., Siu Ting, K., Creevey, C. & Huws, S., 2018.

Research output: Contribution to conferencePoster

Investigating the metabolic function of the Butyrivibrio group

Pidcock, S., Godoy Santos, F., Siu Ting, K., Skvortsov, T., Creevey, C. & Huws, S., 2018.

Research output: Contribution to conferencePoster

2 Citations (Scopus)
140 Downloads (Pure)

Spatial requirement for phenylacetone monooxygenases for transformation of non-native linear substrates

Carvalho, A., Dourado, D., Skvortsov, T., Miguel, D. A., Ferguson, L., Quinn, D., Moody, T. & Huang, M., 03 Jan 2018, In : Physical Chemistry Chemical Physics. p. 1-32

Research output: Contribution to journalArticle

Open Access
File
Mixed Function Oxygenases
requirements
Substrates
mutations
Oxygenation
2017
5 Citations (Scopus)
139 Downloads (Pure)

Catalytic mechanism of Phenylacetone monooxygenases for non-native linear substrates: implications on rational engineering of BVMOs to expand the substrate specificity

Carvalho, A. T. P., Dourado, D. F. A. R., Skvortsov, T., de Abreu, M., Ferguson, L., Quinn, D. J., Moody, T. S. & Huang, M., 07 Sep 2017, In : Physical Chemistry Chemical Physics. 19, 39, p. 26851-26861 11 p.

Research output: Contribution to journalArticle

Open Access
File
Mixed Function Oxygenases
engineering
Substrates
Quantum theory
quantum mechanics

Mining for ancient sirtuins in alpine paleosols

Mackle, J., Skvortsov, T., Allen, C. & Hyland, E. M., 2017.

Research output: Contribution to conferenceAbstract

7 Citations (Scopus)
159 Downloads (Pure)

Temporal dynamics of uncultured viruses: a new dimension in viral diversity

Arkhipova, K., Skvortsov, T., Quinn, J., McGrath, J., Allen, C., Dutilh, B., McElarney, Y. R. & Kulakov, L., 13 Oct 2017, In : The ISME Journal.

Research output: Contribution to journalArticle

Open Access
File
Viral Genome
Metagenomics
virus
genome
Lakes
2016
29 Citations (Scopus)
221 Downloads (Pure)

Metagenomic characterisation of the viral community of lough neagh, the largest freshwater lake in Ireland

Skvortsov, T., De Leeuwe, C., Quinn, J. P., McGrath, J. W., Allen, C. C. R., McElarney, Y., Watson, C., Arkhipova, K., Lavigne, R. & Kulakov, L. A., 29 Feb 2016, In : PLoS ONE. 11, 2, 19 p., e0150361.

Research output: Contribution to journalArticle

Open Access
File
Metagenomics
Caudovirales
Lakes
Fresh Water
Ireland
24 Citations (Scopus)
183 Downloads (Pure)

Rational design of a (S)-selective-Transaminase for asymmetric synthesis of (1S)-1-(1,1'-biphenyl 2-yl)ethanamine

Dourado, D. F. A. R., Pohle, S., Carvalho, A. T. P., Dheeman, D. S., Caswell, J. M., Skvortsov, T., Miskelly, I., Brown, R. T., Quinn, D. J., Allen, C. C. R., Kulakov, L., Huang, M. & Moody, T. S., 04 Oct 2016, In : ACS Catalysis.

Research output: Contribution to journalArticle

Open Access
File
Transaminases
Amines
Ketones
Catalyst activity
Enzymes

Succession of viral species in freshwater lake: a yearlong study

Arkhipova, K., Skvortsov, T., Quinn, J., McGrath, J., Allen, C., Lavigne, R. & Kulakov, L., 2016.

Research output: Contribution to conferenceAbstract

What the lough whispers: detecting the viral gene expression signals in microbial metatranscriptomes

Skvortsov, T., Arkhipova, K., Quinn, J., McGrath, J., Allen, C., Lavigne, R. & Kulakov, L., 2016.

Research output: Contribution to conferenceAbstract

2015
16 Citations (Scopus)
150 Downloads (Pure)

Dormant non-culturable Mycobacterium tuberculosis retains stable low-abundant mRNA

Ignatov, D. V., Salina, E. G., Fursov, M. V., Skvortsov, T. A., Azhikina, T. L. & Kaprelyants, A. S., 16 Nov 2015, In : BMC Genomics. 16, 1, 954.

Research output: Contribution to journalArticle

Open Access
File
Mycobacterium tuberculosis
Bacillus
Messenger RNA
Rifampin
Transcriptome

Evidence of specialised transduction events in the viral population of a freshwater lake.

Arkhipova, K., Skvortsov, T., Quinn, J., McGrath, J., Allen, C., Lavigne, R. & Kulakov, L., 2015.

Research output: Contribution to conferenceAbstract

Metagenomic analysis of microbial and viral communities within a freshwater lake in Northern Ireland

de Leeuwe, C., Skvortsov, T., Quinn, J., McGrath, J., Allen, C., McElarney, Y. R., Watson, C. & Kulakov, L., 2015.

Research output: Contribution to conferenceAbstract

Partial assembly and analysis of bacteriophage genomes from Lough Neagh viromes

de Leeuwe, C., Skvortsov, T., Quinn, J., McGrath, J., Allen, C., McElarney, Y. R., Watson, C. & Kulakov, L., 2015.

Research output: Contribution to conferenceAbstract

2014
1 Citation (Scopus)
144 Downloads (Pure)

Differences in brain transcriptomes of closely related baikal coregonid species

Bychenko, O. S., Sukhanova, L. V., Azhikina, T. L., Skvortsov, T. A., Belomestnykh, T. V. & Sverdlov, E. D., 29 Jan 2014, In : BioMed Research International. 2014, 857329.

Research output: Contribution to journalArticle

Open Access
File
Salmonidae
Transcriptome
Brain
Genes
Fishes
1 Citation (Scopus)

Expression of Small RNAs of Mycobacterium tuberculosis in Murine Models of Tuberculosis Infection

Ignatov, D. V., Timoshina, O. Y., Logunova, N. N., Skvortsov, T. A. & Azhikina, T. L., Mar 2014, In : Russian Journal of Bioorganic Chemistry. 40, 2, p. 233-235 3 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Tuberculosis
RNA
Bacteria
Infection

Using bacterial sequences present in the phage metagenome to assess horizontal gene transfer in industrial and natural water environments

Kulakov, L., Skvortsov, T., De Leeuwe, C., Flanagan, P., Larkin, M., Allen, C. & Quinn, J., 14 Jul 2014.

Research output: Contribution to conferenceAbstract