Personal profile
Interests
My main research interests are in relation interventions to improve maternal and neonatal outcomes, with a particular interest in the impact of educational resources and lifestyle interventions among women with diabetes. Research interests also include investigating biomarkers for the prediction of pre-eclampsia among women with complex pregnancies.
Research Statement
Primary research interests:
• Developing and evaluating educational resources and complex lifestyle interventions in relation to improving maternal and neonatal outcomes for women with complex pregnancies, with a particular interest in the field of diabetes.
• Investigating risk and prophylaxis of pre-eclampsia in women with diabetes and exploring biomarkers for prediction of the condition.
Current projects are funded by a BRIDGES grant from the International Diabetes Federation (supported by an educational grant from Lilly Diabetes), Diabetes UK, The Big Lottery and the Public Health Agency / R&D Office Northern Ireland.
Teaching
Module Coordinator for SSC Lifestyle Through The Life Cycle (1st Year Medical Students)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Collaborations and top research areas from the last five years
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Carbohydrate quantity is more closely associated with glycaemic control than weight in pregnant women with type 1 diabetes: insights from the Diabetes and Pre-eclampsia Intervention Trial (DAPIT)
Hill, A. J., Patterson, C., Young, I. S., Holmes, V. A. & McCance, D. R., 25 May 2022, (Early online date) In: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Link opens in a new tab Citations (Scopus)87 Downloads (Pure) -
FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function
Alqudah, A., Eastwood, K.-A., Jerotic, D., Todd, N., Hoch, D., McNally, R., Obradovic, D., Dugalic, S., Hunter, A. J., Holmes, V. A., McCance, D. R., Young, I. S., Watson, C. J., Robson, T., Desoye, G., Grieve, D. J. & McClements, L., 02 Jun 2021, In: Frontiers in Endocrinology. 12, 650328.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Link opens in a new tab Citations (Scopus)111 Downloads (Pure) -
Role of a novel angiogenesis FKBPL-CD44 pathway in preeclampsia risk stratification and mesenchymal stem cell treatment
Todd, N., McNally, R., Alqudah, A., Jerotic, D., Suvakov, S., Obradovic, D., Hoch, D., Hombrebueno, J. R., Campos, G. L., Watson, C. J., Gojnic-Dugalic, M., Simic, T. P., Krasnodembskaya, A., Desoye, G., Eastwood, K.-A., Hunter, A. J., Holmes, V. A., McCance, D. R., Young, I. S. & Grieve, D. J. & 4 others, , 02 Jan 2021, In: The Journal of Clinical Endocrinology & Metabolism. 106, 1, p. 26-41 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Link opens in a new tab Citations (Scopus)110 Downloads (Pure) -
FKBPL and SIRT-1, key angiogenesis proteins, are downregulated by diabetes in pregnancy
Alqudah, A., Eastwood, K. A., Jerotic, D., Todd, N., Hoch, D., McNally, R., Obradovic, D., Dugalic, S., Hunter, A. J., Holmes, V. A., McCance, D. R., Young, I. S., Watson, C. J., Robson, T., Desoye, G., Grieve, D. J. & McClements, L., 08 Oct 2020, medRxiv, (medRxiv).Research output: Working paper
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Text messaging to help women with overweight or obesity lose weight after childbirth: the intervention adaptation and SMS feasibility RCT
McGirr, C., Rooney, C., Gallagher, D., Dombrowski, S. U., Anderson, A. S., Cardwell, C., Free, C., Hoddinott, P., Holmes, V., McIntosh, E., Somers, C., Woodside, J., Young, I., Kee, F. & McKinley, M., 25 Mar 2020, In: Public Health Research. 8, 4, 186 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile455 Downloads (Pure)
Prizes
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Diabetes UK Education award - Runner Up
Holmes, V. (Recipient), Mar 2014
Prize: Prize (including medals and awards)
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Quality in Care Diabetes Award, UK, for Best Improvement Programme for Pregnancy and Maternity, 2013
Holmes, V. (Recipient), 2013
Prize: Prize (including medals and awards)
Activities
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Eurocat – Primary Prevention of Congenital Anomalies.
Holmes, V. (Invited speaker)
25 Jun 2014Activity: Participating in or organising an event types › Participation in conference
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14th Bergmeyer Conference “Women’s Health”
Holmes, V. (Invited speaker)
04 Mar 2014Activity: Participating in or organising an event types › Participation in conference
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QIC Diabetes Webinar: Improving Patient Care.
Holmes, V. (Invited speaker)
06 Feb 2014Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Northern Ireland Obstetric Ultrasound Forum, 4th Annual Meeting. Newtownabbey.
Holmes, V. (Invited speaker)
Oct 2013Activity: Participating in or organising an event types › Participation in conference
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2nd National Diabetes and Pregnancy Conference, UK
Holmes, V. (Invited speaker)
May 2013Activity: Participating in or organising an event types › Participation in workshop, seminar, course