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Research Output 2014 2019

2019
1 Citation (Scopus)
52 Downloads (Pure)

Therapies for Type 1 Diabetes: Current Scenario and Future Perspectives

Pathak, V., Pathak, N. M., O’Neill, C. L., Guduric-Fuchs, J. & Medina, R. J., 03 May 2019, In : Clinical Medicine Insights: Endocrinology and Diabetes. 12, 13 p.

Research output: Contribution to journalReview article

Open Access
File
Type 1 Diabetes Mellitus
Islets of Langerhans Transplantation
Islets of Langerhans
Diabetes Complications
Insulin
Cell- and Tissue-Based Therapy
Blood Vessels
Regeneration
Pathologic Neovascularization
Ischemic Optic Neuropathy
2017
2 Citations (Scopus)

Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice

Pathak, N. M., Millar, P. J. B., Pathak, V., Flatt, P. R. & Gault, V. A., 01 Aug 2017, In : Molecular and Cellular Endocrinology. 9 p.

Research output: Contribution to journalArticle

Fats
Insulin
Medical problems
Glucagon-Like Peptide 1
Glucose
14 Citations (Scopus)
125 Downloads (Pure)

Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice

Millar, P., Pathak, N. M., Parthsarathy, V., Bjourson, A., O'Kane, M., Moffett, R. C., Flatt, P. R. & Pathak, V., 13 Jun 2017, In : Journal of Endocrinology.

Research output: Contribution to journalArticle

Open Access
File
Neuroprotective Agents
Glucose
Glucagon-Like Peptide 1
Insulin
Energy Intake
2016

(D-Ser2)Oxm[Lys38-γ-glu-PAL] improves hippocampal gene expression and cognition in a mouse model of type 1 diabetes

Pathak, N. M., Irwin, N., Pathak, V. & Flatt, P. R., 31 Mar 2016, In : Journal of Experimental and Integrative Medicine. 6, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Oxyntomodulin
Type 1 Diabetes Mellitus
Cognition
Gene Expression
Streptozocin
13 Citations (Scopus)

Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice

Millar, P. J. B., Pathak, V., Moffett, R. C., Pathak, N. M., Bjourson, A. J., O'Kane, M. J., Flatt, P. R. & Gault, V. A., 15 Jan 2016, In : Molecular and Cellular Endocrinology. 420, p. 37-45 9 p.

Research output: Contribution to journalArticle

Sodium-Glucose Transport Proteins
Fats
Glucose
Peptides
Insulin
2015
33 Citations (Scopus)
Glucagon-Like Peptide 1
Fats
Glucose
Peptides
Cholecystokinin
25 Citations (Scopus)
Gastric Inhibitory Polypeptide
Lipoylation
Obesity
Fats
Insulin
17 Citations (Scopus)

Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice

Pathak, V., Vasu, S., Gault, V. A., Flatt, P. R. & Irwin, N., Sep 2015, In : Diabetologia. 58, 9, p. 2144-2153

Research output: Contribution to journalArticle

Gastric Inhibitory Polypeptide
Glucagon-Like Peptide 1
Peptides
Insulin
Glucose
14 Citations (Scopus)

Stable oxyntomodulin analogues exert positive effects on hippocampal neurogenesis and gene expression as well as improving glucose homeostasis in high fat fed mice

Pathak, N. M., Pathak, V., Lynch, A. M., Irwin, N., Gault, V. A. & Flatt, P. R., 05 Sep 2015, In : Molecular and Cellular Endocrinology. 412, p. 95-103 9 p.

Research output: Contribution to journalArticle

Oxyntomodulin
Neurogenesis
Gene expression
Homeostasis
Fats
7 Citations (Scopus)

Sustained treatment with a stable long-acting oxyntomodulin analogue improves metabolic control and islet morphology in an experimental model of type 1 diabetes

Irwin, N., Pathak, V., Pathak, N. M., Gault, V. A. & Flatt, P. R., Sep 2015, In : Diabetes, Obesity and Metabolism. 17, 9, p. 887-895

Research output: Contribution to journalArticle

Oxyntomodulin
Type 1 Diabetes Mellitus
Theoretical Models
Insulin
Streptozocin
2014
16 Citations (Scopus)

A novel DPP IV-resistant C-terminally extended glucagon analogue exhibits weight-lowering and diabetes-protective effects in high-fat-fed mice mediated through glucagon and GLP-1 receptor activation

Lynch, A. M., Pathak, N., Pathak, V., O'Harte, F. P. M., Flatt, P. R., Irwin, N. & Gault, V. A., Sep 2014, In : Diabetologia. 57, 9, p. 1927-1936 10 p.

Research output: Contribution to journalArticle

Glucagon
Fats
Weights and Measures
Insulin
Glucagon-Like Peptide-1 Receptor
14 Citations (Scopus)

Characterisation of the biological activity of xenin-25 degradation fragment peptides

Martin, C. M. A., Parthsarathy, V., Pathak, V., Gault, V. A., Flatt, P. R. & Irwin, N., May 2014, In : The Journal of endocrinology. 221, 2, p. 193-200

Research output: Contribution to journalArticle

Peptide Fragments
Glucose
Peptides
Insulin
xenin 25
9 Citations (Scopus)
Incretins
Glucagon-Like Peptide 1
Nonesterified Fatty Acids
Gene Expression
Glucose