• Room 01.019 - Pharmacy & MCI

    United Kingdom

Accepting PhD Students

PhD projects

Open to PhD applications in the field of pharmaceutics, vaccine technology, mucosal and thermal analysis including amorphous and polymorphic systems. - Novel mucosal delivery of biofilm penetrating antibiotics - Vaccine delivery via mucosal routes - Novel spray-dried powders for delivery to the lung

20002019

Research output per year

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Personal profile

Interests

Dr. Kett is a member of the Drug Delivery Research Group. Her research interests lie in the development and characterisation of freeze-dried (lyophilised) formats. Examples of these include

  • freeze-dried tablets for mucosal (nasal, sublingual and vaginal) administration of material including HIV vaccine and microbicides.
  • freeze-dried/spray freeze-dried liposomes for nasal/pulmonary delivery.
  • freeze-dried nanoparticles for delivery to the eye


More fundamental research includes investigation into the mechanisms of protein protection during freeze-drying using thermal analysis techniques (DSC, MTDSC and isothermal microcalorimetry) as well as neutron scattering in collaboration with colleagues at the Rutherford Appleton Laboratory.

She has also worked extensively in the use of thermal techniques to characterise amorphous systems and the detection of polymorphic transitions.

Dr. Kett was involved in the foundation of the Clinical Raman microscopy unit together with colleagues from the schools of chemistry and Medicine, Dentistry & Biomedical Science and has published on the use of this technique for the identification of polymorphic changes in pharmaceutical systems.
In 2002 she was awarded the Royal Society of Chemistry Thermal Methods Group Cyril Keattch award for “The Application of Thermoanalytical Techniques to the Study of the Freeze Drying Process”.

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Projects

Research Output

Development and pharmacokinetics of a combination vaginal ring for sustained release of dapivirine and the protein microbicide 5P12-RANTES

McBride, J. W., Malcolm, R. K., Dias, N., Cameron, D., Offord, R. E., Hartley, O., Kett, V. L., Devlin, B. & Boyd, P., 10 Jun 2019, In : International Journal of Pharmaceutics. 564, p. 207-213 7 p.

Research output: Contribution to journalArticle

  • 2 Citations (Scopus)

    The impact of electronic prescription on reducing medication errors in an Egyptian outpatient clinic

    Kenawy, A. S. & Kett, V., 01 Jul 2019, In : International Journal of Medical Informatics. 127, p. 80-87 8 p.

    Research output: Contribution to journalArticle

  • Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES

    McBride, J. W., Boyd, P., Dias, N., Cameron, D., Offord, R. E., Hartley, O., Kett, V. L. & Malcolm, R. K., 01 Mar 2019, In : Journal of Controlled Release. 298, p. 1-11

    Research output: Contribution to journalArticle

    Open Access
    File
  • 8 Citations (Scopus)
    164 Downloads (Pure)

    DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system.

    Cole, G., Ali, A., McCrudden, C., McBride, J., McCaffrey, J., Robson, T., Kett, V., Dunne, N., Donnelly, R. & McCarthy, H., 03 Mar 2018, In : European Journal of Pharmaceutics and Biopharmaceutics. 127, p. 288-297 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 9 Citations (Scopus)
    145 Downloads (Pure)

    Gene Therapy With RALA/iNOS Composite Nanoparticles Significantly Enhances Survival In A Model Of Metastatic Prostate Cancer

    McCrudden, C., McBride, J., McCaffrey, J., McErlean, E., Dunne, N., Kett, V., Coulter, J., Robson, T. & McCarthy, H., 01 Jun 2018, In : Cancer Nanotechnology.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Citations (Scopus)
    165 Downloads (Pure)

    Prizes

    Invent 2014 Life and Health Category

    Victoria Kett (Recipient), Oct 2014

    Prize: Prize (including medals and awards)

  • QUB Green Fund Award

    Maurice Hall (Recipient), Lezley-Anne Hanna (Recipient), Victoria Kett (Recipient), Tara Brown (Recipient) & Claire Lyttle (Recipient), 12 Dec 2019

    Prize: Prize (including medals and awards)

  • Activities

    External Examiner, PhD

    Victoria Kett (Examiner)
    2015

    Activity: Examination typesPhD external examination

    Invited Talk

    Victoria Kett (Speaker)
    2015

    Activity: Talk or presentation typesInvited talk

    Royal Society of Chemistry, Thermal Methods Group. Thermal Analysis and Calorimetry 2013

    Victoria Kett (Member of the organising committee)
    08 Apr 201310 Apr 2013

    Activity: Participating in or organising an event typesParticipation in conference

    External Examiner PhD, School of Pharmacy, University of East Anglia

    Victoria Kett (Examiner)
    01 Apr 201310 May 2013

    Activity: Examination typesPhD external examination

    External Examiner, PhD School of Pharmacy, University College London

    Victoria Kett (Examiner)
    08 May 2013

    Activity: Examination typesPhD external examination