Projects per year
Personal profile
Research Focus
www.atlasilab.com
We are interested in mechanisms of epigenetic regulation in health and disease. We use embryonic stem cells and tissue derived organoids, as two main experimental models, to explore the epigenetic parallels between embryonic, adult, and cancer stem cells. For this aim, we use state-of-the-art genomics and proteomics approaches combined with computational biology to make fundamental discoveries that can ultimately solve important health challenges within society.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 3 Active
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R1109CNR: Mechanisms of chromatin regulation downstream of USP7-PRC1.6 in stem cells and cancer
Atlasi, Y. (PI)
18/11/2022 → …
Project: Research
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R2943CNR: Deciphering the role of USP7 and EED in drug resistant Non-Hodgkin lymphomas: a novel approach to patient treatment.
Atlasi, Y. (PI) & Mills, K. (CoI)
01/11/2022 → …
Project: Research
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R2867CNR: Identification of enhancer SNPs at 14q24.1 that influence predisposition to male and female breast cancer
Orr, N. (PI) & Atlasi, Y. (CoI)
24/03/2022 → …
Project: Research
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The epigenetic landscape in intestinal stem cells and its deregulation in colorectal cancer
Larue, A. E. M. & Atlasi, Y., Jun 2024, In: Stem Cells. 42, 6, p. 509–525 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure) -
Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain
Lister, K. C., Wong, C., Uttam, S., Parisien, M., Stecum, P., Brown, N., Cai, W., Hooshmandi, M., Gu, N., Amiri, M., Beaudry, F., Jafarnejad, S. M., Tavares-Ferreira, D., Inturi, N. N., Mazhar, K., Zhao, H. T., Fitzsimmons, B., Gkogkas, C. G., Sonenberg, N. & Price, T. J. & 4 others, , 28 Jun 2024, 37 p.Research output: Working paper
File12 Downloads (Pure) -
Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1
Chalkiadaki, K., Hooshmandi, M., Lach, G., Statoulla, E., Simbriger, K., Amorim, I. S., Kouloulia, S., Zafeiri, M., Pothos, P., Bonneil, É., Gantois, I., Popic, J., Kim, S.-H., Wong, C., Cao, R., Komiyama, N. H., Atlasi, Y., Jafarnejad, S. M., Khoutorsky, A. & Gkogkas, C. G., 01 May 2023, In: Brain. 146, 5, p. 2175-2190 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)30 Downloads (Pure) -
Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency
Mirzadeh Azad, F., Struys, E. A., Wingert, V., Hannibal, L., Mills, K., Jansen, J. H., Longley, D. B., Stunnenberg, H. G. & Atlasi, Y., 18 Aug 2023, In: Science Advances. 9, 33, 14 p., eadg7997.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)34 Downloads (Pure) -
CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia
Venney, D., Greenfield, G. M., Cairns, L. V., Strain, P., McGill, Á. E., Morgan, J. J., McAvera, R. M., Mirzadeh, F., Atlasi, Y., Mohd-Sarip, A. & Mills, K. I., 15 Nov 2022, In: Blood. 140, Supplement 1, p. 8702-8703Research output: Contribution to journal › Meeting abstract › peer-review
Prizes
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Queen's CATALYST award RGEF20/02
Atlasi, Y. (Recipient), 01 Mar 2021
Prize: Prize (including medals and awards)
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Young Investigator Award: Iranian Genetic Society
Atlasi, Y. (Recipient), 2016
Prize: National/international honour
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WntUK at Crick Institute
Atlasi, Y. (Participant)
29 Apr 2024Activity: Participating in or organising an event types › Participation in conference
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Joint BSDB / Genetics Society Spring Meeting on Developmental Genetics
Atlasi, Y. (Speaker)
15 Apr 2024Activity: Participating in or organising an event types › Participation in conference
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Joost Gribnau
Atlasi, Y. (Host)
11 Apr 2024Activity: Hosting a visitor types › Hosting an academic visitor
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AI for De-coding the Enhancer Language
Rafiee, R. (Organiser) & Atlasi, Y. (Speaker)
09 Apr 2024Activity: Other activity types › Other
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Harvard Rare Disease Hackathon
Atlasi, Y. (Organiser)
02 Mar 2024Activity: Participating in or organising an event types › Participation in conference