Projects per year
Personal profile
Research Focus
www.atlasilab.com
We are interested in mechanisms of epigenetic regulation in health and disease. We use embryonic stem cells and tissue derived organoids, as two main experimental models, to explore the epigenetic parallels between embryonic, adult, and cancer stem cells. For this aim, we use state-of-the-art genomics and proteomics approaches combined with computational biology to make fundamental discoveries that can ultimately solve important health challenges within society.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 3 Active
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R1109CNR: Mechanisms of chromatin regulation downstream of USP7-PRC1.6 in stem cells and cancer
18/11/2022 → …
Project: Research
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R2867CNR: Identification of enhancer SNPs at 14q24.1 that influence predisposition to male and female breast cancer
24/03/2022 → …
Project: Research
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Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1
Chalkiadaki, K., Hooshmandi, M., Lach, G., Statoulla, E., Simbriger, K., Amorim, I. S., Kouloulia, S., Zafeiri, M., Pothos, P., Bonneil, É., Gantois, I., Popic, J., Kim, S-H., Wong, C., Cao, R., Komiyama, N. H., Atlasi, Y., Jafarnejad, S. M., Khoutorsky, A. & Gkogkas, C. G., 01 May 2023, In: Brain. 146, 5, p. 2175-2190 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency
Mirzadeh Azad, F., Struys, E. A., Wingert, V., Hannibal, L., Mills, K., Jansen, J. H., Longley, D. B., Stunnenberg, H. G. & Atlasi, Y., 18 Aug 2023, In: Science Advances. 9, 33, 14 p., eadg7997.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia
Venney, D., Greenfield, G. M., Cairns, L. V., Strain, P., McGill, Á. E., Morgan, J. J., McAvera, R. M., Mirzadeh, F., Atlasi, Y., Mohd-Sarip, A. & Mills, K. I., 15 Nov 2022, In: Blood. 140, Supplement 1, p. 8702-8703Research output: Contribution to journal › Meeting abstract › peer-review
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CHD4 loss in acute myeloid leukaemia gives rise to altered cell cycle progression and increased sensitivity to hypomethylating agents
Venney, D., Cairns, L., Atlasi, Y., Mohd-Sarip, A. & Mills, K., 18 Oct 2022, In: Experimental Hematology. 111, Supplement, p. S152-S153 3216.Research output: Contribution to journal › Meeting abstract › peer-review
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Functional role of lncRNAs in gastrointestinal malignancies: the peculiar case of small nucleolar RNA host gene family
Saeinasab, M., Atlasi, Y. & Matin, M. M., 14 Nov 2022, (Early online date) In: The FEBS Journal. 33 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile19 Downloads (Pure)
Prizes
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Queen's CATALYST award RGEF20/02
Atlasi, Yaser (Recipient), 01 Mar 2021
Prize: Prize (including medals and awards)
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Young Investigator Award: Iranian Genetic Society
Atlasi, Yaser (Recipient), 2016
Prize: National/international honour
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Cancer Knows No Borders – Celebrating Tripartite Cooperation to Enhance Cancer Research
Yaser Atlasi (Participant)
13 Mar 2023Activity: Participating in or organising an event types › Participation in conference
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Leukaemia Lymphoma NI Patient day
Yaser Atlasi (Recipient)
18 Feb 2023Activity: Other activity types › Other
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Crick Cancer Research Symposium
Yaser Atlasi (Participant)
03 Oct 2022Activity: Participating in or organising an event types › Participation in conference
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Fantastic enhancers and where to find them, a tale of stem cells and cancer
Yaser Atlasi (Advisor)
2022Activity: Talk or presentation types › Invited talk
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Fantastic enhancers and where to find them, a tale of stem cells and cancer
Yaser Atlasi (Advisor)
2022Activity: Talk or presentation types › Invited talk