Discovery of an integrated risk profile for chronic kidney disease and development of a clinical biomarker panel for personalising medicine (Stratified medicine for chronic kidney disease)

McKnight, Amy Jayne (PI)
Maxwell, Peter (CoI)

School of Medicine, Dentistry and Biomedical Sciences

Acronym	R3789CPH
Status	Finished
Effective start/end date	15/06/2016 → 31/12/2023

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

21 Article
5 Abstract
2 Chapter
2 Chapter (peer-reviewed)
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Harnessing genomic analysis to explore the role of telomeres in the pathogenesis and progression of diabetic kidney disease
Hill, C., Duffy, S., Coulter, T., Maxwell, A. P. & McKnight, A. J., 28 Feb 2023, In: Genes. 14, 3, 609.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
6 Citations (Scopus)

77 Downloads (Pure)
Longitudinal epigenome-wide analysis of kidney transplant recipients pretransplant and posttransplant
Smyth, L. J., Kerr, K. R., Kilner, J., McGill, Á. E., Maxwell, A. P. & McKnight, A. J., 01 Feb 2023, In: Kidney International Reports. 8, 2, p. 330-340 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
6 Citations (Scopus)

86 Downloads (Pure)
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K.-H. H., Ntalla, I., Hui, Q. & Klarin, D. & 31 others, Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Havulinna, A. S., Veturi, Y., Pacheco, J. A., Weir, D. R., Brown, M. R., Smyth, L. J., Cañadas-Garre, M., Li, X., Nelson, C. P., McKnight, A. J., Kee, F., Wilson, P., Brown, C. D. & Million Veterans Program, 04 Aug 2022, In: The American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
21 Citations (Scopus)

37 Downloads (Pure)

JDRF Diabetic Nephropathy Collaborative Research Initiative GWAS in the T2D Knowledge Portal
McKnight, A. J. (Creator), Queen's University Belfast, Dec 2018
DOI: 10.17034/0bb13952-988a-46ae-a5f4-b76f78f6f6ba, http://type2diabetesgen-qasrvr.elasticbeanstalk.com/informational/data
Dataset

4 Invited talk
3 Participation in workshop, seminar, course
3 Invited or keynote talk at national or international conference
2 Contribution to the work of national or international committees and working groups
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European Diabetic Nephropathy Study Group - 36th Annual Meeting
McKnight, A. J. (Chair)
17 May 2024 → 18 May 2024
Activity: Participating in or organising an event types › Participation in conference
Invited member of MRC Prevention Task and Finish Group
McKnight, A. J. (Member)
01 Oct 2023 → 01 Feb 2024
Activity: Consultancy types › Contribution to the work of national or international committees and working groups
Diabetes: Nature or Nurture
McKnight, A. J. (Keynote speaker)
26 Apr 2023 → 28 Apr 2023
Activity: Talk or presentation types › Invited or keynote talk at national or international conference

Albert Nelson Marquis Lifetime Achievement Award
McKnight, A. J. (Recipient), 2019
Prize: Prize (including medals and awards)
Expert in diabetic nephropathy
McKnight, A. J. (Recipient), 30 Dec 2018
Prize: Prize (including medals and awards)
Leader in Diabetes Complications
McKnight, A. J. (Recipient), 07 Feb 2019
Prize: Prize (including medals and awards)

Hamilton announces £3.6 million investment in research funding
McKnight, A. J.
08/09/2016
1 Media contribution
Press/Media: Other

Discovery of an integrated risk profile for chronic kidney disease and development of a clinical biomarker panel for personalising medicine (Stratified medicine for chronic kidney disease)

Project Details

UN Sustainable Development Goals

Fingerprint

Harnessing genomic analysis to explore the role of telomeres in the pathogenesis and progression of diabetic kidney disease

Longitudinal epigenome-wide analysis of kidney transplant recipients pretransplant and posttransplant

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

JDRF Diabetic Nephropathy Collaborative Research Initiative GWAS in the T2D Knowledge Portal

European Diabetic Nephropathy Study Group - 36th Annual Meeting

Invited member of MRC Prevention Task and Finish Group

Diabetes: Nature or Nurture

Albert Nelson Marquis Lifetime Achievement Award

Expert in diabetic nephropathy

Leader in Diabetes Complications

Hamilton announces £3.6 million investment in research funding

Discovery of an integrated risk profile for chronic kidney disease and development of a clinical biomarker panel for personalising medicine (Stratified medicine for chronic kidney disease)

Project Details

UN Sustainable Development Goals

Fingerprint

Research output

Datasets

Activities

Prizes

Press/Media