α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion

Imre Lengyel; Kerry A. Nichol; Max R. Bennett; John W. Heath; Gerald J. Little; John A P Rostas

α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion

Imre Lengyel, Kerry A. Nichol, Max R. Bennett, John W. Heath, Gerald J. Little, John A P Rostas^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

THE ciliary ganglion of the chicken contains only two types of neurons. Using monoclonal antibodies against the α and the β subunits of Ca²⁺/calmodulin-stimulated protein kinase II (CaMPK-II) we found that the α-subunit was localized to the choroid neurons while β subunit was associated with the ciliary neurons. As both neurons receive their inputs from the oculomotor nerve, while their postganglionic axons leave via different nerves, the ciliary ganglion of the chicken is a neuronal system in which the functional differences between a and β CaMPK-II homopolymers in the regulation of synaptic transmission can be investigated.

Original language	English
Pages (from-to)	2753-2755
Number of pages	3
Journal	Neuroreport
Volume	9
Issue number	12
Publication status	Published - 24 Aug 1998
Externally published	Yes

Keywords

Ca/calmodulin-dependent protein kinase II
Ciliary ganglion
Protein phosphorylation
Synaptic transmission

ASJC Scopus subject areas

General Neuroscience

Cite this

@article{174af907eea04f47ac523674429eaffc,

title = "α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion",

abstract = "THE ciliary ganglion of the chicken contains only two types of neurons. Using monoclonal antibodies against the α and the β subunits of Ca2+/calmodulin-stimulated protein kinase II (CaMPK-II) we found that the α-subunit was localized to the choroid neurons while β subunit was associated with the ciliary neurons. As both neurons receive their inputs from the oculomotor nerve, while their postganglionic axons leave via different nerves, the ciliary ganglion of the chicken is a neuronal system in which the functional differences between a and β CaMPK-II homopolymers in the regulation of synaptic transmission can be investigated.",

keywords = "Ca/calmodulin-dependent protein kinase II, Ciliary ganglion, Protein phosphorylation, Synaptic transmission",

author = "Imre Lengyel and Nichol, {Kerry A.} and Bennett, {Max R.} and Heath, {John W.} and Little, {Gerald J.} and Rostas, {John A P}",

year = "1998",

month = aug,

day = "24",

language = "English",

volume = "9",

pages = "2753--2755",

journal = "Neuroreport",

issn = "0959-4965",

publisher = "Lippincott Williams & Wilkins",

number = "12",

}

TY - JOUR

T1 - α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion

AU - Lengyel, Imre

AU - Nichol, Kerry A.

AU - Bennett, Max R.

AU - Heath, John W.

AU - Little, Gerald J.

AU - Rostas, John A P

PY - 1998/8/24

Y1 - 1998/8/24

N2 - THE ciliary ganglion of the chicken contains only two types of neurons. Using monoclonal antibodies against the α and the β subunits of Ca2+/calmodulin-stimulated protein kinase II (CaMPK-II) we found that the α-subunit was localized to the choroid neurons while β subunit was associated with the ciliary neurons. As both neurons receive their inputs from the oculomotor nerve, while their postganglionic axons leave via different nerves, the ciliary ganglion of the chicken is a neuronal system in which the functional differences between a and β CaMPK-II homopolymers in the regulation of synaptic transmission can be investigated.

AB - THE ciliary ganglion of the chicken contains only two types of neurons. Using monoclonal antibodies against the α and the β subunits of Ca2+/calmodulin-stimulated protein kinase II (CaMPK-II) we found that the α-subunit was localized to the choroid neurons while β subunit was associated with the ciliary neurons. As both neurons receive their inputs from the oculomotor nerve, while their postganglionic axons leave via different nerves, the ciliary ganglion of the chicken is a neuronal system in which the functional differences between a and β CaMPK-II homopolymers in the regulation of synaptic transmission can be investigated.

KW - Ca/calmodulin-dependent protein kinase II

KW - Ciliary ganglion

KW - Protein phosphorylation

KW - Synaptic transmission

UR - http://www.scopus.com/inward/record.url?scp=0032563589&partnerID=8YFLogxK

M3 - Article

C2 - 9760115

AN - SCOPUS:0032563589

SN - 0959-4965

VL - 9

SP - 2753

EP - 2755

JO - Neuroreport

JF - Neuroreport

IS - 12

ER -

α and β subunits of CaM-kinase II are localized in different neurons in chick ciliary ganglion

Abstract

Keywords

ASJC Scopus subject areas

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