3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)

D.G. Smith; M. Buffet; A.E. Fenwick; David Haigh; R.J. Ife; M. Saunders; B.P. Slingsby; R. Stacey; R.W. Ward

3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)

D.G. Smith
, M. Buffet
, A.E. Fenwick
, David Haigh
, R.J. Ife
, M. Saunders
, B.P. Slingsby
, R. Stacey
, R.W. Ward

Research output: Contribution to journal › Article › peer-review

Abstract

Potent 3-anilino-4-arylmaleimide glycogen synthase kinase-3 (GSK-3) inhibitors have been prepared using automated array methodology. A number of these are highly selective, having little inhibitory potency against more than 20 other protein kinases. (C) 2001 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	635-639
Number of pages	5
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	11
Issue number	5
Publication status	Published - 12 Mar 2001

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Organic Chemistry
Drug Discovery
Pharmaceutical Science

Cite this

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title = "3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)",

abstract = "Potent 3-anilino-4-arylmaleimide glycogen synthase kinase-3 (GSK-3) inhibitors have been prepared using automated array methodology. A number of these are highly selective, having little inhibitory potency against more than 20 other protein kinases. (C) 2001 Elsevier Science Ltd. All rights reserved.",

author = "D.G. Smith and M. Buffet and A.E. Fenwick and David Haigh and R.J. Ife and M. Saunders and B.P. Slingsby and R. Stacey and R.W. Ward",

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AU - Smith, D.G.

AU - Buffet, M.

AU - Fenwick, A.E.

AU - Haigh, David

AU - Ife, R.J.

AU - Saunders, M.

AU - Slingsby, B.P.

AU - Stacey, R.

AU - Ward, R.W.

PY - 2001/3/12

Y1 - 2001/3/12

N2 - Potent 3-anilino-4-arylmaleimide glycogen synthase kinase-3 (GSK-3) inhibitors have been prepared using automated array methodology. A number of these are highly selective, having little inhibitory potency against more than 20 other protein kinases. (C) 2001 Elsevier Science Ltd. All rights reserved.

AB - Potent 3-anilino-4-arylmaleimide glycogen synthase kinase-3 (GSK-3) inhibitors have been prepared using automated array methodology. A number of these are highly selective, having little inhibitory potency against more than 20 other protein kinases. (C) 2001 Elsevier Science Ltd. All rights reserved.

UR - https://www.scopus.com/pages/publications/0035848403

M3 - Article

SN - 1464-3405

VL - 11

SP - 635

EP - 639

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

IS - 5

ER -

3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)

Abstract

ASJC Scopus subject areas

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