3D printing in ophthalmology: from medical implants to personalised medicine

Greymi Tan; Nicole Ioannou; Essyrose  Mathew; Aristides D. Tagalakis; Dimitrios A. Lamprou; Cynthia Yu-Wai-Man

doi:10.1016/j.ijpharm.2022.122094

3D printing in ophthalmology: from medical implants to personalised medicine

Greymi Tan, Nicole Ioannou, Essyrose Mathew, Aristides D. Tagalakis, Dimitrios A. Lamprou^*, Cynthia Yu-Wai-Man^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Review article › peer-review

33 Citations (Scopus)

110 Downloads (Pure)

Abstract

3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. These advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits.

Original language	English
Article number	122094
Number of pages	8
Journal	International Journal of Pharmaceutics
Volume	625
Early online date	11 Aug 2022
DOIs	https://doi.org/10.1016/j.ijpharm.2022.122094
Publication status	Published - 25 Sept 2022

Keywords

3D Printing
Ophthalmology
implants
Drug delivery
Personalised Medicine
Bioprinting
Additive Manufacturing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ijpharm.2022.122094Licence: CC BY

3D printing in ophthalmology: from medical implants to personalised medicine
Copyright 2022 The Authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 1.29 MBLicence: CC BY

Novel systems for transdermal and intradermal drug delivery
Mathew, E. (Author), Lamprou, D. (Supervisor), Donnelly, R. (Supervisor) & Larraneta Landa, E. (Supervisor), Jul 2023
Student thesis: Doctoral Thesis › Doctor of Philosophy

Cite this

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title = "3D printing in ophthalmology: from medical implants to personalised medicine",

abstract = "3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. These advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits.",

keywords = "3D Printing, Ophthalmology, implants, Drug delivery, Personalised Medicine, Bioprinting, Additive Manufacturing",

author = "Greymi Tan and Nicole Ioannou and Essyrose Mathew and Tagalakis, {Aristides D.} and Lamprou, {Dimitrios A.} and Cynthia Yu-Wai-Man",

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doi = "10.1016/j.ijpharm.2022.122094",

language = "English",

volume = "625",

journal = "International Journal of Pharmaceutics",

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T1 - 3D printing in ophthalmology: from medical implants to personalised medicine

AU - Tan, Greymi

AU - Ioannou, Nicole

AU - Mathew, Essyrose

AU - Tagalakis, Aristides D.

AU - Lamprou, Dimitrios A.

AU - Yu-Wai-Man, Cynthia

PY - 2022/9/25

Y1 - 2022/9/25

N2 - 3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. These advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits.

AB - 3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. These advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits.

KW - 3D Printing

KW - Ophthalmology

KW - implants

KW - Drug delivery

KW - Personalised Medicine

KW - Bioprinting

KW - Additive Manufacturing

U2 - 10.1016/j.ijpharm.2022.122094

DO - 10.1016/j.ijpharm.2022.122094

M3 - Review article

SN - 0378-5173

VL - 625

JO - International Journal of Pharmaceutics

JF - International Journal of Pharmaceutics

M1 - 122094

ER -

3D printing in ophthalmology: from medical implants to personalised medicine

Abstract

Keywords

UN SDGs

Access to Document

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Student theses

Novel systems for transdermal and intradermal drug delivery

Cite this