A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions

Conor McGarry, Craig McCreery, Prakash Jeevanandam, Raymond King, Alan Hounsell, Suneil Jain, Fraser Buchanan

Research output: Contribution to conferenceAbstract

Abstract

Introduction Patients with prostate cancer are increasingly receiving a boost dose to dominant intra-prostatic lesions (DILs) as part of their radiotherapy treatment. Validation of the dose to the boost region is challenging due to the small volume. The aim of this investigation was to 3D print a patient-specific phantom to validate prostate SABR boost plan. Method The patient outline and bone structure were segmented on their CT scan using the treatment planning system. A cylindrical module positioned at the location of the prostate was added and used to encapsulate dosimeters (film and pinpoint ionization chamber (PP)). Each element was printed using a RepRap X400 3D printer. The bone was printed using Stonefil filament with variable infill. The pelvis and dosimetry inserts were printed using PETG as shells and filled with water. A SABR plan was delivered to the phantom with film placed through the boost region and a PP placed at positions within the prostate and boost regions. The films were compared to the dose calculation using the FilmProQA with global gamma analysis performed using a 2%/2mm criteria and 10% threshold. The plans were recalculated on the phantom and directly compared with the original patient plan using the Verisoft software (global gamma analysis at 1%/1mm and 10% threshold). Results Outlines of the external contour and the bones were consistent between the phantom and patient CT scans. Dose comparisons between the phantom and patient plan calculation revealed 99.0±0.3% of pixels were within 1%/1mm. Prostate and boost point doses were within ±1.5% of expected. Pass rates for film were > 91% at 2%/2mm and > 98.5% at 3%/3mm. Areas of failure coincided with air gaps between the slices of the phantom. Conclusions A bespoke pelvic phantom was designed, constructed and validated to ensure the safe delivery of SABR prostate boost plans.
LanguageEnglish
Publication statusPublished - 27 Jun 2019
EventPathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery: Programme: IAS workshop 26th to 27th June 2019 - Surrey, United Kingdom
Duration: 26 Jun 201927 Jun 2019
http://www.ias.surrey.ac.uk/workshops/3ddose/

Conference

ConferencePathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery
CountryUnited Kingdom
CitySurrey
Period26/06/201927/06/2019
Internet address

Fingerprint

Pelvis
Prostate
Bone and Bones
Prostatic Neoplasms
Radiotherapy
Software
Air
Water
Therapeutics

Cite this

McGarry, C., McCreery, C., Jeevanandam, P., King, R., Hounsell, A., Jain, S., & Buchanan, F. (2019). A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions. Abstract from Pathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery, Surrey, United Kingdom.
McGarry, Conor ; McCreery, Craig ; Jeevanandam, Prakash ; King, Raymond ; Hounsell, Alan ; Jain, Suneil ; Buchanan, Fraser. / A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions. Abstract from Pathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery, Surrey, United Kingdom.
@conference{0d17c1d662294cb1b82cf146a4f3ec0b,
title = "A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions",
abstract = "Introduction Patients with prostate cancer are increasingly receiving a boost dose to dominant intra-prostatic lesions (DILs) as part of their radiotherapy treatment. Validation of the dose to the boost region is challenging due to the small volume. The aim of this investigation was to 3D print a patient-specific phantom to validate prostate SABR boost plan. Method The patient outline and bone structure were segmented on their CT scan using the treatment planning system. A cylindrical module positioned at the location of the prostate was added and used to encapsulate dosimeters (film and pinpoint ionization chamber (PP)). Each element was printed using a RepRap X400 3D printer. The bone was printed using Stonefil filament with variable infill. The pelvis and dosimetry inserts were printed using PETG as shells and filled with water. A SABR plan was delivered to the phantom with film placed through the boost region and a PP placed at positions within the prostate and boost regions. The films were compared to the dose calculation using the FilmProQA with global gamma analysis performed using a 2{\%}/2mm criteria and 10{\%} threshold. The plans were recalculated on the phantom and directly compared with the original patient plan using the Verisoft software (global gamma analysis at 1{\%}/1mm and 10{\%} threshold). Results Outlines of the external contour and the bones were consistent between the phantom and patient CT scans. Dose comparisons between the phantom and patient plan calculation revealed 99.0±0.3{\%} of pixels were within 1{\%}/1mm. Prostate and boost point doses were within ±1.5{\%} of expected. Pass rates for film were > 91{\%} at 2{\%}/2mm and > 98.5{\%} at 3{\%}/3mm. Areas of failure coincided with air gaps between the slices of the phantom. Conclusions A bespoke pelvic phantom was designed, constructed and validated to ensure the safe delivery of SABR prostate boost plans.",
author = "Conor McGarry and Craig McCreery and Prakash Jeevanandam and Raymond King and Alan Hounsell and Suneil Jain and Fraser Buchanan",
year = "2019",
month = "6",
day = "27",
language = "English",
note = "Pathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery : Programme: IAS workshop 26th to 27th June 2019 ; Conference date: 26-06-2019 Through 27-06-2019",
url = "http://www.ias.surrey.ac.uk/workshops/3ddose/",

}

McGarry, C, McCreery, C, Jeevanandam, P, King, R, Hounsell, A, Jain, S & Buchanan, F 2019, 'A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions' Pathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery, Surrey, United Kingdom, 26/06/2019 - 27/06/2019, .

A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions. / McGarry, Conor; McCreery, Craig; Jeevanandam, Prakash ; King, Raymond; Hounsell, Alan; Jain, Suneil; Buchanan, Fraser.

2019. Abstract from Pathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery, Surrey, United Kingdom.

Research output: Contribution to conferenceAbstract

TY - CONF

T1 - A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions

AU - McGarry, Conor

AU - McCreery, Craig

AU - Jeevanandam, Prakash

AU - King, Raymond

AU - Hounsell, Alan

AU - Jain, Suneil

AU - Buchanan, Fraser

PY - 2019/6/27

Y1 - 2019/6/27

N2 - Introduction Patients with prostate cancer are increasingly receiving a boost dose to dominant intra-prostatic lesions (DILs) as part of their radiotherapy treatment. Validation of the dose to the boost region is challenging due to the small volume. The aim of this investigation was to 3D print a patient-specific phantom to validate prostate SABR boost plan. Method The patient outline and bone structure were segmented on their CT scan using the treatment planning system. A cylindrical module positioned at the location of the prostate was added and used to encapsulate dosimeters (film and pinpoint ionization chamber (PP)). Each element was printed using a RepRap X400 3D printer. The bone was printed using Stonefil filament with variable infill. The pelvis and dosimetry inserts were printed using PETG as shells and filled with water. A SABR plan was delivered to the phantom with film placed through the boost region and a PP placed at positions within the prostate and boost regions. The films were compared to the dose calculation using the FilmProQA with global gamma analysis performed using a 2%/2mm criteria and 10% threshold. The plans were recalculated on the phantom and directly compared with the original patient plan using the Verisoft software (global gamma analysis at 1%/1mm and 10% threshold). Results Outlines of the external contour and the bones were consistent between the phantom and patient CT scans. Dose comparisons between the phantom and patient plan calculation revealed 99.0±0.3% of pixels were within 1%/1mm. Prostate and boost point doses were within ±1.5% of expected. Pass rates for film were > 91% at 2%/2mm and > 98.5% at 3%/3mm. Areas of failure coincided with air gaps between the slices of the phantom. Conclusions A bespoke pelvic phantom was designed, constructed and validated to ensure the safe delivery of SABR prostate boost plans.

AB - Introduction Patients with prostate cancer are increasingly receiving a boost dose to dominant intra-prostatic lesions (DILs) as part of their radiotherapy treatment. Validation of the dose to the boost region is challenging due to the small volume. The aim of this investigation was to 3D print a patient-specific phantom to validate prostate SABR boost plan. Method The patient outline and bone structure were segmented on their CT scan using the treatment planning system. A cylindrical module positioned at the location of the prostate was added and used to encapsulate dosimeters (film and pinpoint ionization chamber (PP)). Each element was printed using a RepRap X400 3D printer. The bone was printed using Stonefil filament with variable infill. The pelvis and dosimetry inserts were printed using PETG as shells and filled with water. A SABR plan was delivered to the phantom with film placed through the boost region and a PP placed at positions within the prostate and boost regions. The films were compared to the dose calculation using the FilmProQA with global gamma analysis performed using a 2%/2mm criteria and 10% threshold. The plans were recalculated on the phantom and directly compared with the original patient plan using the Verisoft software (global gamma analysis at 1%/1mm and 10% threshold). Results Outlines of the external contour and the bones were consistent between the phantom and patient CT scans. Dose comparisons between the phantom and patient plan calculation revealed 99.0±0.3% of pixels were within 1%/1mm. Prostate and boost point doses were within ±1.5% of expected. Pass rates for film were > 91% at 2%/2mm and > 98.5% at 3%/3mm. Areas of failure coincided with air gaps between the slices of the phantom. Conclusions A bespoke pelvic phantom was designed, constructed and validated to ensure the safe delivery of SABR prostate boost plans.

UR - http://www.ias.surrey.ac.uk/workshops/3ddose/

M3 - Abstract

ER -

McGarry C, McCreery C, Jeevanandam P, King R, Hounsell A, Jain S et al. A bespoke modular 3D printed pelvis phantom for validation of prostate SABR with dominant intra-prostatic lesion (DIL) boost regions. 2019. Abstract from Pathways to in-vivo 3D dosimetry measurements for adaptive radiation delivery, Surrey, United Kingdom.