A comparison of Agiolax and lactulose in elderly patients with chronic constipation

A P Passmore, K W Davies, P G Flanagan, C Stoker, M G Scott

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

In a double-blind crossover study the efficacies of Agiolax, a combination of fibre and senna pod, and lactulose were compared in 77 long-stay elderly patients with chronic constipation. Mean daily bowel frequency, stool consistency and ease of evacuation were significantly greater with Agiolax than lactulose. The recommended dose was exceeded more frequently with lactulose than Agiolax (chi 2 = 8.38, p <0.01). Adverse effects were not different for the 2 treatments. In long-stay elderly patients with chronic constipation Agiolax and lactulose were well tolerated, but Agiolax proved a more effective treatment.
Original languageEnglish
Pages (from-to)249-52
Number of pages4
JournalMolecular Pharmacology
Volume47 Suppl 1
Publication statusPublished - 1993

Fingerprint

Dive into the research topics of 'A comparison of Agiolax and lactulose in elderly patients with chronic constipation'. Together they form a unique fingerprint.

Cite this