A concise and convergent (formal) total synthesis of huperzine A

John Mann, C. Lucey, S. Kelly

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The first convergent synthesis of the tricyclic skeleton of huperzine A is described and includes, as the key step, an efficient regioselective intramolecular Heck reaction of 2-(tert-butyldimethylsillyoxymethyl)-6-(2-methoxy-5-bromopyridin-6-yl)methylcyclohex-2-enol.
Original languageEnglish
Pages (from-to)301-306
Number of pages6
JournalOrganic and Biomolecular Chemistry
Volume5(2)
Issue number2
DOIs
Publication statusPublished - Jan 2007

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)

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