A Concise Approach to a Gelsemine Core Structure using an Oxygen to Carbon Bridge Swapping Strategy

Kirill Tchabanenko, Nigel S. Simpkins, Louise Male

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

A tricyclic core structure related to gelsemine was synthesized from an oxabicyclo[3.2.1]octanone by a three-step bridge swapping strategy involving elimination of the bridging ether oxygen and intramolecular Michael addition of a tethered cyanoacetamide unit.
Original languageEnglish
Pages (from-to)4747-4750
Number of pages4
JournalOrganic Letters
Volume10
Issue number21
Early online date07 Oct 2008
DOIs
Publication statusPublished - 06 Nov 2008

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Physical and Theoretical Chemistry

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