A CRUK first-in-human phase I trial of LY3143921, a novel CDC7 inhibitor, in patients with advanced solid tumors.

Peter F. Gallagher; Gregory Naylor; Saira Bashir; Xiangfei Yan; David Burke; Elizabeth Ruth Plummer; T.R. Jeffry Evans; Victoria M. Coyle; Sally Clive; Lesley McGuigan; Kathrin Heinzmann; Gavin Halbert; Gareth Veal; Eleanor Tiplady; Shelby Barnett; Krishna Yalla; Sue Brook; Nicola Dobbs; Richard H. Wilson

doi:10.1200/jco.2022.40.16_suppl.3103

A CRUK first-in-human phase I trial of LY3143921, a novel CDC7 inhibitor, in patients with advanced solid tumors.

Peter F. Gallagher, Gregory Naylor, Saira Bashir, Xiangfei Yan, David Burke, Elizabeth Ruth Plummer, T.R. Jeffry Evans, Victoria M. Coyle, Sally Clive, Lesley McGuigan, Kathrin Heinzmann, Gavin Halbert, Gareth Veal, Eleanor Tiplady, Shelby Barnett, Krishna Yalla, Sue Brook, Nicola Dobbs, Richard H. Wilson

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Meeting abstract › peer-review

Original language	English
Article number	3103
Journal	Journal of Clinical Oncology
Volume	40
Issue number	16_suppl
DOIs	https://doi.org/10.1200/jco.2022.40.16_suppl.3103
Publication status	Published - 01 Jun 2022
Event	2022 ASCO Annual Meeting - Chicago, United States Duration: 03 Jun 2022 → 07 Jun 2022

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Gallagher, P. F., Naylor, G., Bashir, S., Yan, X., Burke, D., Plummer, E. R., Evans, T. R. J., Coyle, V. M., Clive, S., McGuigan, L., Heinzmann, K., Halbert, G., Veal, G., Tiplady, E., Barnett, S., Yalla, K., Brook, S., Dobbs, N., & Wilson, R. H. (2022). A CRUK first-in-human phase I trial of LY3143921, a novel CDC7 inhibitor, in patients with advanced solid tumors. Journal of Clinical Oncology, 40(16_suppl), Article 3103. https://doi.org/10.1200/jco.2022.40.16_suppl.3103

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title = "A CRUK first-in-human phase I trial of LY3143921, a novel CDC7 inhibitor, in patients with advanced solid tumors.",

author = "Gallagher, {Peter F.} and Gregory Naylor and Saira Bashir and Xiangfei Yan and David Burke and Plummer, {Elizabeth Ruth} and Evans, {T.R. Jeffry} and Coyle, {Victoria M.} and Sally Clive and Lesley McGuigan and Kathrin Heinzmann and Gavin Halbert and Gareth Veal and Eleanor Tiplady and Shelby Barnett and Krishna Yalla and Sue Brook and Nicola Dobbs and Wilson, {Richard H.}",

year = "2022",

month = jun,

day = "1",

doi = "10.1200/jco.2022.40.16_suppl.3103",

language = "English",

volume = "40",

journal = "Journal of Clinical Oncology",

issn = "0732-183X",

publisher = "Lippincott Williams and Wilkins",

number = "16_suppl",

note = "2022 ASCO Annual Meeting ; Conference date: 03-06-2022 Through 07-06-2022",

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Gallagher, PF, Naylor, G, Bashir, S, Yan, X, Burke, D, Plummer, ER, Evans, TRJ, Coyle, VM, Clive, S, McGuigan, L, Heinzmann, K, Halbert, G, Veal, G, Tiplady, E, Barnett, S, Yalla, K, Brook, S, Dobbs, N & Wilson, RH 2022, 'A CRUK first-in-human phase I trial of LY3143921, a novel CDC7 inhibitor, in patients with advanced solid tumors.', Journal of Clinical Oncology, vol. 40, no. 16_suppl, 3103. https://doi.org/10.1200/jco.2022.40.16_suppl.3103

TY - JOUR

T1 - A CRUK first-in-human phase I trial of LY3143921, a novel CDC7 inhibitor, in patients with advanced solid tumors.

AU - Gallagher, Peter F.

AU - Naylor, Gregory

AU - Bashir, Saira

AU - Yan, Xiangfei

AU - Burke, David

AU - Plummer, Elizabeth Ruth

AU - Evans, T.R. Jeffry

AU - Coyle, Victoria M.

AU - Clive, Sally

AU - McGuigan, Lesley

AU - Heinzmann, Kathrin

AU - Halbert, Gavin

AU - Veal, Gareth

AU - Tiplady, Eleanor

AU - Barnett, Shelby

AU - Yalla, Krishna

AU - Brook, Sue

AU - Dobbs, Nicola

AU - Wilson, Richard H.

PY - 2022/6/1

Y1 - 2022/6/1

U2 - 10.1200/jco.2022.40.16_suppl.3103

DO - 10.1200/jco.2022.40.16_suppl.3103

M3 - Meeting abstract

SN - 0732-183X

VL - 40

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

IS - 16_suppl

M1 - 3103

T2 - 2022 ASCO Annual Meeting

Y2 - 3 June 2022 through 7 June 2022

ER -