A European perspective on progress in moving away from the mouse bioassay for marine-toxin analysis

Katrina Campbell, N. Vilarino, L.M. Botana, Christopher Elliott

Research output: Contribution to journalArticlepeer-review

56 Citations (Scopus)

Abstract

This review considers the ethical and technical problems currently associated with employing mouse bioassays for marine-toxin analysis and the challenges and the difficulties that alternative methods must overcome before being deemed applicable for implementation into a regulatory monitoring regime. We discuss proposed alternative methods, classified as functional, immunological and analytical, for well-established European toxins as well as emerging toxins in European waters, highlighting their advantages and disadvantages. We also consider emerging tools and technologies for future toxin analysis.
Original languageEnglish
Pages (from-to)239-253
Number of pages15
JournalTRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume30
Issue number2
DOIs
Publication statusPublished - Feb 2011

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Environmental Chemistry

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