A European perspective on progress in moving away from the mouse bioassay for marine-toxin analysis

Katrina Campbell; N. Vilarino; L.M. Botana; Christopher Elliott

doi:10.1016/j.trac.2010.10.010

A European perspective on progress in moving away from the mouse bioassay for marine-toxin analysis

Katrina Campbell, N. Vilarino, L.M. Botana, Christopher Elliott

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

76 Citations (Scopus)

Abstract

This review considers the ethical and technical problems currently associated with employing mouse bioassays for marine-toxin analysis and the challenges and the difficulties that alternative methods must overcome before being deemed applicable for implementation into a regulatory monitoring regime. We discuss proposed alternative methods, classified as functional, immunological and analytical, for well-established European toxins as well as emerging toxins in European waters, highlighting their advantages and disadvantages. We also consider emerging tools and technologies for future toxin analysis.

Original language	English
Pages (from-to)	239-253
Number of pages	15
Journal	TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/j.trac.2010.10.010
Publication status	Published - Feb 2011

ASJC Scopus subject areas

Analytical Chemistry
Spectroscopy
Environmental Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.trac.2010.10.010

Cite this

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abstract = "This review considers the ethical and technical problems currently associated with employing mouse bioassays for marine-toxin analysis and the challenges and the difficulties that alternative methods must overcome before being deemed applicable for implementation into a regulatory monitoring regime. We discuss proposed alternative methods, classified as functional, immunological and analytical, for well-established European toxins as well as emerging toxins in European waters, highlighting their advantages and disadvantages. We also consider emerging tools and technologies for future toxin analysis.",

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AB - This review considers the ethical and technical problems currently associated with employing mouse bioassays for marine-toxin analysis and the challenges and the difficulties that alternative methods must overcome before being deemed applicable for implementation into a regulatory monitoring regime. We discuss proposed alternative methods, classified as functional, immunological and analytical, for well-established European toxins as well as emerging toxins in European waters, highlighting their advantages and disadvantages. We also consider emerging tools and technologies for future toxin analysis.

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JO - TRAC-TRENDS IN ANALYTICAL CHEMISTRY

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A European perspective on progress in moving away from the mouse bioassay for marine-toxin analysis

Abstract

ASJC Scopus subject areas

UN SDGs

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